These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Breather Boss: Morpheel. The fight is sandwiched between a very frustrating dungeon and the emotional/plotline climax of the first half of the game. If anything, the fight is more finnicky than hard. In fact, you have to really try in order to take damage from the second form, despite the fact that if the game actually obeyed the laws of physics, Link would probably die quickly just from the pressure waves caused by something that huge swimming around.
Armogohma. The first phase of the battle is incredibly straightforward and the second phase is literally a joke. As with Morpheel, you really have to try in order to get hurt in this fight.
Breather Level: The entire second half of the game after the lost woods. With no more Twilight realms, the ability to transform into a wolf at will, and the fact that you've grown stronger at a much faster rate than your adversaries, life is good.
A common criticism of this game is that it's an It's the Same, so It Sucks rehash of the games that came before it. Meanwhile defenders will point out that the game is still a well made installment that adds more original elements than it's often given credit for, and that it is part of a series that, as a whole, was Strictly Formula to begin with.
One that is debated among both detractors and fans is Ganondorf's appearance. It is either one of the series' greatest Boss Battles or an unnecessary Ass Pull which undermines Zant's character.
Demonic Spiders: The ReDeads in this game are some of the hardest enemies to deal with, since if you get in certain range of it, it instantly does its infamous shriek, then it hit you with its BFS and takes off a big portion of your health.
Ilia. Link/Zelda and Link/Midna shippers blow her overreaction to Epona's minor injury out of proportion until she is a complete Jerkass, even though Ilia herself admitted she overreacted and apologized to Link for it.
There's some, but not quite as much, of this toward Zelda. Generally though, the more mature Link/Zelda and Link/Midna shippers tend to get along.
Mortal Draw. It takes a little practice, but is by no means difficult — if you can perfect re-sheathing your sword mid-battle, you can oneshot any regular enemy, and kill bosses in three or four hits. And you can get it about midway through the game.
Ooccoo within the dungeons. There is a trick that if you warp out of the dungeon and then save, you can go back to the exact same spot you warped from after saving. This is especially useful if you're short on time and don't want to go all the way through the dungeon again.
It only works in the second dungeon, but switching out the boots just before landing on a magnetized surface allows you to walk at normal speed across the ceiling (putting them back on and off to drop). You can't roll or use items, but it is a lot faster (and quieter).
There's also the glitch that allows you to use infinite bombs and arrows (and thus infinite bomb arrows) through exploiting the minigames on Zora's River.
Those on the "They changed it" side complain that Twilight Princess is not 'Zelda' enough due to being somewhat linear in comparison, especially towards the beginning where is has to open the sandbox ([[Fandumb though this one's a bit silly considering that most Zelda games, including Ocarina and Wind Waker are guilty of this]])
Memetic Mutation: Just as this was invoked in-universe, the Malo Mart dance also became a meme online — see here and here.
Earlier than that Zant mortally wounds Midna, who while still jerk had grown on the player by that point. You then have to carry her to Zelda as she begs you to hurry. When you reach Zelda, you learn it was so Zelda could help you not her. You then watch as Zelda sacrifices herself for Midna, despite her pleads not to.
Les Yay: Midna and Zelda exchange plenty of meaningful dialogue and looks and are very motivated in helping one another, to the point of Heroic Sacrifice. Midna often gives Zelda a grin. Also a little questionable is that Midna call Zelda 'Twilight Princess' when that's her title. How do you think she could also be called that?
Scrappy Mechanic: Some players aren't too fond of the "put rupees back in chests if wallet can't hold them all" mechanic.
That One Sidequest: Bringing a barrel of springwater across Hyrule Field. Not only is the barrel a One Hitpoint Wonder that doesn't survive being hit by enemies or thrown, the enemies are Giant Fliers (who flap in very close, making it difficult to see what's going on), plants (who circle around you in ever-tighter circles), and Bulbins (who shoot your barrel full of arrows). And to top it all off, it's a Timed Mission, killing all enemies before moving on only ensures the water cools down and therefore useless. Fortunately, you get a piece of heart out of it.
The fandom has tons of it for this game, especially since (except for the ones listed under Happily Married) there are no Official Couples. The Link/Midna shippers equal, if not outnumber, the Link/Zelda shippers. Of course, then there's the Link/Zelda/Midna threesome option. And then of course there's Ilia to factor in to the equation....
Shad's also very popular with the shippers, being the only other Bishōnen in the game. He's paired with both Zelda and Midna as often as Link, and also with fellow La Résistance member Ashei. Yaoi fans also enjoy slashing him with Link.
That One Level: The Lost Woods. A twisting labyrinth of samey-looking chambers and passageways where you have to chase after the Skull Kid while fending off the endless Deku Puppets he summons. The first time you're forced to get through it as a wolf and the second time the Skull Kid isn't carrying a lantern, requiring you to track him down by sound alone.
Uncanny Valley: Ooccoo, who is basically a chicken with a human head. Much more unsettling than it sounds. Her son, Ooccoo Jr., who is a child's disembodied head with wings on the sides, is even worse.
Zant. During the boss battle with him, and the scene immediately before, he twists into various unnatural positions, and makes some very odd high-pitched noises. He is possibly even more creepy-looking when he's not wearing his huge robe and helmet, due to his creepy eyes and proportions being easier to see.
Midna's true form is certainly quite beautiful, but hearing that same childish voice coming out of that Amazon body? REALLY unsettling.
Vindicated by History: When this game came out, it became socially acceptable not only to like Wind Waker, but to start comparing it to Twilight Princess favorably. Now, once Skyward Sword came out, suddenly the same happened to this game. By the time the next Zelda game is released, everybody will probably lighten up to Skyward Sword too.