"Now, remember son: stay in school, eat your veggies, and burn everything but Shakespeare."
The main protagonist of the film. He is a chameleon with aspirations for the stage and stardom, but most of all desires companionship. After being accidentally thrown out of his owner's car, he starts his journey towards his destiny.
A ranch owner, this desert iguana found Rango and brought him to Dirt. She suspects that something has happened to the water supply of the town, that someone is throwing the water out into the desert.
A young cactus mouse (or, if you believe Verbinski, an aye-aye) in the town of Dirt. At first she dismisses Rango as "funny-lookin'", she grows to admire him near the end. She has her own pair of revolvers, seems a little too excited about violence and death, and likes to make fun of strangers.
He is the mayor of the town of Dirt, who appoints Rango as the sheriff after killing the hawk
. He is the wealthiest citizen in Dirt, and is a polite gentleman
to the townsfolk, supporting their wishes of a better life. Early in the film, he is the only character with access to the town's supply of water, which makes Beans particularly suspicious. He's also responsible for sealing the water from getting it to the town, which is part of his grand plan to construct a more modern city outside the borders of Dirt (implied to be inspired by seeing the Las Vegas cityscape), which would eventually make it obsolete and the townsfolk forced to move or to face death
Voiced by: Ned Beatty
"You got killer in your eyes, son? I don't see it."
A fearsome, ferocious desert rattlesnake with a gatling gun for a tail and the secondary
antagonist. He is called the Grim Reaper and lauded by many as a ruthless killer who "doesn't leave a town without taking a soul." He secretly worked for the Mayor until near the end when the Mayor turned on Jake.
Voiced by Bill Nighy.
Part of the posse
. A horned toad with a simpleton personality and less than appropriate amount of teeth. Regarding to his official information, he writes "surprisingly bad haiku."
Voiced by James "Jim" Ward Byrkit
- Abusive Parents: His father made him cough up marshmallows he had eaten the last evening for breakfast.
- Cloud Cuckoolander: Although everybody (sans Rango, Beans and Wounded Bird) in the town could be considered this, Waffles is perhaps the most prominent example.
- The Fool
- Friendly Enemy: Acts as one towards one of the inbred rodents for a very brief moment, warning him that he's about to hit his head.
- Kindhearted Simpleton
- Manchild: Waffles has a childlike personality and matching intelligence.
Part of the posse
and Rango's deputy. A Native American raven who is a quiet bystander and uses a crutch of some sort to help himself walk. His general information from the movie's website states that his tracking skills are legendary and that he's big in Finland for reasons unknown.
Voiced by Gil Birmingham
Part of the posse
. An owl of some sort, dresses like a gentleman and, according to his official information, is a professional gambler and can speak in 12 languages.
Voiced by Ian Abercrombie
The Mariachi Owls
Rock-Eye the Toad
- Necessary Evil: The townsfolk of Dirt are frightened of the hawk, but if it dies, Rattlesnake Jake might show up. Nobody wants that.
- Silent Snarker: Has no dialogue outside of screeching, but smirks at Rango while operating the vending machine.
Mr. Johannes "Fluffy Joe" Merrimack III