A dying woman gives one to the eponymous Paranoia Agent, Lil Slugger. He can't take it, busts a wall and a bunch of stuff, and runs.
Dewey Novak gives one to Holland in Eureka Seven that ranges from how he's utterly failed at what he was trying to accomplish to that no one reads the Gekko State's self-published magazine ray=out. Immediately followed by a Shut Up, Hannibal! moment when Dewey is shocked by the sight of Renton and Eureka piloting Nirvash, and Holland points out Renton has accomplished what he and Dewey failed to do.
Shin of Fist of the North Star coolly chastises Kenshiro after crippling him and taking the love of his life away: "The thing you lacked that caused your defeat at my hands? It's desire and ambition."
Mazinger Z: In the manga episodes penned by Gosaku Ota, during the final battle Big Bad Dr. Hell orders Count Brocken -one of his CoDragons- go and battle Mazinger... in spite of Brocken was a normal-sized human and he had no weapons to take down a Humongous Mecha! Brocken reluctantly agrees... but before leaving he tells EXACTLY what he thinks of Hell, calling him out on all his failures and flaws, blaming him for their defeats, bitterly stating he does not care his troops risk their lives everyday, and making very clear he served Hell out of gratitude -for saving his life- but he never wanted working for such an inept. Then he announces if he survives he will return to Germany before leaving to fight as Hell threw a fit. It was a Crowning Moment of Awesome for Brocken.
Tengen Toppa Gurren Lagann: It turns out that the Antispiral's method of dealing with potentially reality-rending amounts of accumulating Spiral Energy without outright killing its hosts (at least initially) is to simply suppress their fighting spirit by making them live hopeless lives. In Simon and crew's last battle against the Antispiral King, said Big Bad constantly taunts them with the potential implications of their actions, and debates out loud if they truly have the ambition, determination, and resolve to go through with their plans. He does so while beating the shit out of them, saying they've reached their limit.
Sousuke attempts to give one to Takuma during the Behemoth Arc in the Full Metal Panic novels. Takuma failed his overall mission, had his Humongous Mecha destroyed, was slowly dying a painful death, and his only sister that he loved died. When he bemoaned his fate and asked why he failed, Sousuke took the question literally and tactlessly started telling him why he sucked. Kaname tells him to shut up, and Tessa resumes comforting Takuma.
Near's final speech to Light Yagami in Death Note. Also a Kirk Summation, as he responds to Light's claim that he is God of the new world and that no one else could carry out justice like he does by saying that he's nothing more than a murderer, and in believing himself a god who can decide what is just and what is not, he is arguably even worse than those who would use the notebook for personal gain.
The Spider Queen in xXxholic gives one to Watanuki about being overly willing to throw away his own life for others,
Spider Queen: "You're giving yourself away too easily. Do you really think I would accept something that you would throw away so lightly? Zashiri-Warashi tried so hard to get your sight back, and now you just gave it away, just like that. You must think she's a fool, to go through so much effort for something you treat like garbage."
"Immaculate being, was it? In this secular existence, perfection is an illusion. Regardless of all those who utter the contrary, this is the reality. Common man seeks it out. They aspire to achieve it, as if it were some tangible thing. But the fact of the matter is perfection is a hollow shell. It is devoid of any substance. I spit on perfection! Perfection, after all, implies you've reached the summit: no trial and error...no ability to conceptualize. An omniscient being would have no need for such superfluous things. Am I making myself clear? For those who dabble in the sciences, such as ourselves, perfection would render us obsolete. Many magnificent things have been, and will continue to come into existence, and yet every last one of them will fall short of perfection's finish line. Our function as men of science relies on their many shortcomings. Then, and only then, can we apply the fruits of our labour. To put it simply, as soon as you began spouting that nonsense about being an immaculate being, your fate was sealed.HOW DARE YOU CALL YOURSELF A MAN OF SCIENCE!"
Isshin Kurosaki's short explanation to Grand Fisher about why he had to lose.
Gin gives one to Ichigo in chapter 406 when the latter seems to be in Heroic BSOD and/or easily distracted, which disgusts Gin. It was actually a Stealth Mentor's advice. Gin wanted Ichigo to break out of his Heroic BSOD to fight Aizen.
Gin: "Sure it's okay to be looking behind when I'm standing in front of you like this? That's it for you, man. You aren't a warrior anymore. Not a shinigami, nor a Hollow. Not even a person. You think you, standing here in such a half-assed state like that, are gonna be able to stand up to an opponent that those three have lost to?"
Ichigo himself gives a few early in the series. One example is an exchange between him and Grand Fisher.
Grand Fisher: You're dead, sonny! But I'll say this for your sake. Of all I've faced... you were the youngest, the most reckless, the weakest Soul Reaper ever! (gets stabbed in the shoulder) Hey...
A member of Squad 0 gives a delightful one to Soi-Fon when she forgets who she's speaking to:
"Quit fucking around? You took the words right out of my mouth. Remember what you are? YOU'RE a part of the Gotei 13. That ring a bell? The imperial Special Forces' job is to protect the Spirit Palace. The Gotei 13's job is to protect Soul Society. As someone who bears the name Gotei... don't come crying to us 'bout how help didn't come because you couldn't do shit. You're a disgrace to your title!"
Fate: "...Jack Rakan. Even now I do not understand his words, but, I do understand that your fist is not as heavy as his. Why is it, Quintum? Why is your fist, so very light?"
After Negi starts to crack after one of Fate's speeches, Asuna gives Negi her own "The Reason You Suck" Speech, the point being that he's an idiot for even considering what Fate is saying. The next time Fate attempts one of these, he gets a punch in the gut and a Shut Up, Hannibal! for his trouble.
Yue also gave one to Kotarou in the school festival arc.
Askeladd gives this to Thorfinn at least once in Vinland Saga. He basically tells him that his whole quest is pointless, and that he always loses because he's too thickheaded and stubborn in battle. He is also too thickheaded and stubborn to listen to this advice.
Possibly in Gundam 00 this was delivered from Nena Trinity to Wang Liu Mei, telling the latter about how she was becoming an overly greedy, high and mighty Smug Snake, thus robbing her off her soul and the former thinks people like that are better off dead. Cue to Evil Laugh as the former shoots down the ship where the latter was located, with all the controls and maneuver locked by the former, as the latter had an epic Oh Crap planted on her face.
Subverted when Nena gets a Reason You Suck Speech from Ribbons then Louise Halevy right before the latter finally exacts her revenge on Nena while she is under similar conditions.
Hallelujah loves these, seriously he dishes them out like it's going out of style
Hallelujah: "How does it feel to have your life slowly ground away by one sided violence?""There's no possible way you can defeat us AS YOU RELY ON VEDA TOO MUCH!"
Naruto, Sasuke gives two of these to Orochimaru after he betrays him, stating that his attempts at achieving power are revolting and cannot put him on the same level as the Uchihas, whose power he covets.
Earlier then that Neji, before his Heel Face Turn enjoyed telling this to his opponents (Hinata and Naruto respectively) just because they didn't fit his view of following fate. In both cases they pretty much turned it back on him completely. Kabuto also did this to Naruto during their fight right before Naruto drove a Rasengan into his stomach.
Neji also gives some to Lee, saying someone without ninjutsu cannot surpass him as a ninja. Lee doesn't do as well at retorting as Hinata and Naruto do.
Neji: You nitwit. If you can't use ninjutsu or genjutsu, then you can hardly call yourself a ninja, can you? Do you remember when they told you you were the first person to graduate who could only use taijutsu? They weren't saying that because it was impressive. They only meant that it was unusual.
Sasuke much later gets one directed at himself by Danzo, telling him that he's just trying to take out of his hate on someone even if it makes his clan's and especially his brother's death completely meaningless.
It arguably even acts as something of an Ironic Echo of Sasuke's earlier speech, highlighting the Motive Decay both fell to.
Sasuke, to Orochimaru: What do you hope to accomplish? Scurrying from one hideout to the next, conducting your pathetic experiments, using up people's lives one after the other, trying to unlock the mysteries of nature. You toy with people's lives for the sake of this vain and ridiculous cause of yours. You disgust me!
Danzo, to Sasuke: You have the same eyes as Itachi, but not his perception. The truth doesn't mean anything to you. You simply writhe in the grip of your hate, just wanting to lash out at everything. You have wasted the Uchihas' sacrifice.
Kin gives one of these to Sakura as she's keeping her restrained by the hair. "My my, what soft and shiny hair. But you know what? If you spent a little less time shampooing, and a little more time practicing your jutsu, you might not be in this fix! Hey Zaku, I know what would be fun. Let's make Ms. Beauty Queen watch while you finish off that Sasuke guy!"
Sakura's Shut Up, Hannibal! moment shortly thereafter, where she cuts her own hair off to free herself, is thereby made much more awesome.
Shikamaru gives one of these to Hidan shortly before blowing him up.
Shikamaru: You and your god don't frighten me. You see, you and I believe in different things. You wanna know what I believe in? The Will of Fire. Right now, the god you should be worried about isn't your stupid Jashin or anyone else. It's me... because I'm the one who's about to pass judgement!"
Hashirama gives one to Madara after he had stabbed him in the back after fooling Madara with the most basic trick in Naruto's handbook, the Clone Feint:
[[spoiler: —>Madara: A...Mokuton Bushin...*looks down at the sword in his chest* when did you...maneuver...behind my back?
Akainu gives one regarding Whitebeard, saying that he is a failure of a pirate who couldn't become King of the Pirates and that his "family" is worthless, especially considering that he is going to die to protect one of his "sons" who was tricked into stabbing him (as part of Akainu's plan).
Luffy gives them to Kuro and Wapol, saying that they don't have what it takes to be real pirates, as the former tried to escape his reputation as a pirate while the latter had no respect for Hiruluk's Jolly Roger and only pretended to be a pirate.
Hell, Luffy does this just about every time he fights the main villain of an arc.
Luffy gives himself one while fighting Arlong, listing all the things his crew could do that he couldn't. He finishes though, by stating the one thing he could do... kick Arlong's ass.
Franky and the rest of his Family give Usopp one after stealing his money, ridiculing him as weak and ridiculing the crew for having him protect the money. It ultimately influences his decision to temporarily quit the crew.
More like a Reason You Suck Debate between the both of them, the one that Shinigami-sama shares with Ashura near the end of the Soul Eater anime counts:
Shinigami: This is how you've been as long as I've known you. Hiding cowardice behind cunning. You were always riddled with insecurities and plagued by fears, unable to relax until you'd hidden them all! In an effort to escape your petty fear, you partnered with Vajra. You should have fought alongside me, but you were too weak for that! In the end, you betrayed not only innocent humans, but your own Weapon Partner as well! Ashura: Ya know, for a Grim Reaper you're impressively naive. Following the rules doesn't guarantee and escape from fea—- Shinigami-sama: And insanity does?! Even if you bury your fears and madness, new fears will only surface!! Are you truly so lost already that you can't understand that simple fact!?! I you continue along the path you've chosen, the world will sink into despair!! Even a child would see the heartless evil in that!! Ashura: Don't you see how empty and meaningless the authority you impose is? That's not how the truth is found. You make your followers feel safe by offering white lies and comforting words. Don't you know that only harms them more? Shinigami: There's no hope for you!! You are behind saving!! Ashura: Do you find creating the illusion of peace for people that noble of a job? Shinigami: It's far more noble than seeking to destroy them with blind insanity like you intend to!! Ashura: Have you even listened to a word I've said old man!?! What's wrong with surrendering to madness? That's where the true peace is... Shinigami: So you keep saying; but that's because you're not strong enough for sanity!!! Ashura:I'm plenty strong. You'll find out soon enough that YOU'RE the weak one Reaper.
Heroic example: In GaoGaiGar Final, after Guy powers up the Genesic GaoGaiGar, while beating the shit out of Palparepa, he delivers this speech, saying that the reason the 11 Soul Masters: tried to immobilize GGG, destroyed Gao Figh Gar, didn't attack them on Earth, was because they feared their power.
Professor Satou to Judai in Yu-Gi-Oh! GX. Judai is having all his monsters turned against him and is told the whole reason he's losing is because he actually enjoys dueling, so when the fun goes away he has no motivation. And why is he getting in Judai's way and putting his life on the line? Because Judai was sleeping in class. Which Judai comes to realize might not have meant anything to him, but was basically ruining Satou's life since most other students were following Judai's example.
Right before defeating Judai earlier in the season, Edo gives one of these to him.
In the manga, Judai gives one to Ryuga, a Smug Snake teacher candidate who looks down on Osiris Reds and confiscates their cards after they lose to him (and Judai doesn't even know that Ryuga is also cheating and scheming to take over Duel Academy), telling Ryuga he's a "disgrace" and that he refuses to consider him a duelist.
Seto Kaiba of the original Yu-Gi-Oh! seldom met one of these he didn't like.
He's at the receiving end of one from Tea in the Duelist Kingdom arc, after forcing Yugi forfeit by threatening to jump off a ledge if he attacked—and sending Yugi into Heroic BSOD. Capped off by an Armor-Piercing Question.
Tea: What do you have? What do you have at the end of the day? Tell me! TELL ME!
Yugi himself gives Marik an epic variation of this trope near the end of the duel against the brainwashed Jyounouchi, claiming that Marik will be the loser in the end.
Yugi also gives one to Noah after he defeats Kaiba with his deck master, Shinato, claiming that he is heartless and barren, which makes Kaiba better than him.
Touma at several points gives one of these, one as early as the 4th episode to Kanzaki Kaori, who just trashed him. He points out that their 'new policy' towards Index is incredibly selfish and that, well, she sucks.
Last Order takes this trope and reverses it, by giving Accelerator a "the reason you don't suck" speech. Accelerator himself isn't sure how to respond to that.
Alucard from Hellsing does this to people/vampires who make him sick due to their pretentiousness and how pathetic they are.
Often when they failed to kill him and just realize that they probably just can't. Though he is much more pissed in certaincircumstances.
He also recalled when he got one of these from Abraham Van Helsing.
In Code Geass, Bismarck gives a short one of these to Suzaku, basically calling him out on his Chronic Backstabbing Disorder and Motive Decay, pointing out that the very things he's abandoned in his quest for power were what made him strong in the first place. Predictably, Bismarck won that fight, even if Suzaku escaped thanks to a coincidental distraction from Lelouch. The Emperor also does it several times, once when Lelouch was a kid and twice after, though at least the latter two times Lelouch knows enough to shoot it down.
Lelouch, being frustrated for the last failed attempt to kill him, also gives one to Rollo, and it's particularly dramatic since Rollo ends up being really shocked by it, in spite of the fact that he would still be able to kill Lelouch in that very instant.
Lelouch gives one to his parents as they are being absorbed by the Collective Unconscious. He calls them out on turning their back on the future by pursuing the Ragnarok Connection and their selfishness in choosing to sacrifice their children, content with the belief that Utopia Justifies the Means.
In Black Lagoon, Rock gives one to Revy when he for the first time had enough of her behavior. It was so effective, it almost made her cry. Even more impressive considering her initial response was to pull a gun on him, and he just pulled it away before she put one between his eyes.
Revy gets to deliver one to Chaka during their second fight.
Balalaika: As I said, the end of the line. If you were able to think rationally it would have been obvious to you, that as you pursued us you were being led to your death. Take a look at yourself now: a pathetic little brat who's beyond all repair. And like it or not, this is where you're gonna die. Hansel/Gretel: ...Heh. You're funny, lady. But what are you talking about? I'm not going to die. I can't die. Because... I killed so many people in my life. We've killed many... Many... Many... Many people. It means we get to live on for... That much longer. We can add on to our lives... So we're never going to die. That's right. We are eternal. Balalaika: That's quite the interesting religion. It's a wonderful thought, I suppose. However, I'm afraid that Oingo Boingo said it best: "No One Lives Forever", that's just the way it goes. Now then, I suppose I could be cruel and torture you before I kill you — considering what you did to my comrade, there's no question that it would be appropriate. But unfortunately, I am not as vulgar as you; it would bring me no satisfaction. So I think I'll sit here and watch until you've taken your last miserable breath. Judging by your wounds, you have about ten minutes at best. I dedicate these last few minutes before you leave this Earth to Sahalov and Menshof's souls, may they rest in peace... Although I'm certain you wouldn't be able to understand. * Hansel/Gretel starts crying in pain* Balalaika: Don't cry, you fool.
In chapter 50 of Mirai Nikki Kousaka gives one of these to Yukiteru right before Yukiteru shoots him.
"Yukiteru, do you know just why I hate you so much? It's because your crying face resembles my stupid dog at home! Even now...! *punches Yukiteru* That face your making right now! Don't go crying when you made this choice yourself! You're just a damn lowlife who killed his friends for his own convenience! You don't have a right to cry!"
Shion: (To Satoko, after throwing her against some lockers) "Can't you understand what he's (Satoshi) going through?"
Satoko: "Help! Help me, nii-nii!"
Shion *kicks Satoko* "It's because you're like that! *throws books at Satoko* If you want to cry, cry! But you know, you're not going to solve anything by crying! Why are you crying? Because you think that by crying someone will help you? And that person who helps you, will take however much pain there is in your place? Do you realize just how unthinkable that is?! You understand?! Your sins, that is! He'd be better off if you weren't here. If things are painful for you, just die! Don't make things painful for Satoshi-kun! Suffer alone, and die alone! You'd be better off dead!"
Shion: "Don't think it's okay to cry! Don't just think you can always cling to Satoshi-kun! If only...If only you weren't here!!!"
And then a "World of Cardboard" Speech occurs later in the same arc, where Satoko admits that she's been depending on her brother for too long, and now that she's being tortured to death, she won't cry anymore so that she can prove how strong she's become. Bonus points for making Shion realize how much she sucks for not realizing that torturing Satoko isn't what Satoshi wanted her to do.
A rare villain-to-villain speech is given in the second season from Okonogi to Takano Miyo after she refuses to surrender.
Durarara!!: Simon punches Izaya in the face and gives him one.
Lovely Complex: Risa likes to hand these out after punching people to get them to calm down and think more rationally. She's done this to Otani and Mimi.
Canaan: Played with in episode 10 when Hakko tries twice to kill Liang Qi with one of these (which she can actually do due to her superpower) only to have Liang Qi troll her on both accounts and then deliver her own Reason You Suck Speech right back at Hakko each time; to add insult to injury, Hakko finds to her dismay that she accidentally killed Santana with her second speech, which Liang Qi all too gleefully informs her of during her second speech.
And Alphard gives a minor one earlier in the series to Canaan as she defeats her in the women's restroom at the formal dinner. She says that now Canaan is acting out of hatred like she has but Alphard has gotten over that or at least learned to control herself. Canaan ends up so physically and mentally beaten her normal grace deserts her and as she flees she slips and collapses on a roof top.
Rurouni Kenshin: Every time Kenshin fights an opponent, the opponent gives him this, mainly for being on the Imperialist's side. But Kenshin always manages to prove them wrong, or at least prove that he may not agree with them but doesn't suck like they say he does.
Kenshin himself gets a rather scathing one from his old master, Hiko Seijuurou XIII, who was more than a little bitter about Kenshin abandoning his training to help the Imperialists. He helps him anyway though.
Katekyo Hitman Reborn!: Both Byakuran and Mukuro gave Tsuna some of these during their respective battles with him.
Kimblee: "Eh...if you'd been able to fight in your present condition, I'd have stayed silent. In the same breath that you spoke of "pride as a Homunculus" you ran screaming to steal the body of one of the lower life-forms you so despise, just to escape your own predicament. You are... hideous."
And the Truth gives one to Father/Homunculus right before having its own gate swallow it.
Father gives a rather harsh one to Hohenheim in Brotherhood.
One from Ling to Greed after Greed kills one of the previous Greed's friends
If you turn your back on something you wanted, then you don't deserve to call yourself 'Greed'!
Also one from Hohenheim to Father. It backfires, as Father decides to show how he can "give birth" by releasing the people of Xerxes and then unleashing an attack while Hohenheim, the brothers and Izumi are distracted with horror and disgust.
Hohenheim: Why do you look down on us so much? Philosopher's stones are born from humans and homunculi are born from those stones. But what can be made from homunculi? What do they give birth to? Can a being that can only destroy truly be called a god? You think you're the ultimate being, but you're actually just a dead end.
Shalott to Agito in chapter 279 of Air Gear: "All you've done so far is bully the weaklings which is what makes you so weak."
Uzuki to Yuki in Uragiri wa Boku no Namae wo Shitteiru in episode 2 "You're a nuisance. I hate your goody two-shoes, know-it-all act. I'm not your friend. I felt bad for you, so I thought I'd try being nice, but you misunderstood. No one needs you."
Revolutionary Girl Utena has one delivered by Anthy to her brother Akio, the Big Bad of the show, as a Crowning Moment of Awesome: By all means, stay in this cozy coffin of yours and continue to play prince. But I have to go now. She isn't gone at all, she's merely vanished from your world.
And Touga gives one to Utena in episode 12 after defeating her. "Even though you fancied yourself to be a prince in the end you were just a girl. Despite what you may have hoped for your hopes didn't become reality."
The end of the Mai-Otome manga has one of these, in which the protagonist "Manshiro" tells the Big Bad that he does not love anyone, not even himself.
Schwarzwald of The Big O delivers one from beyond the grave! As Big Duo devours Alan Gabriel
Schwarzwald: You! You possess the foolishness of both man and machine.
Alan: Shut Up!
Schwarzwald: It chooses one who wields the power of God created by man. One who can comitt to a single truth. That is Not the case with you!
Big Duo: [Ye Guilty appears on cockpit]
In Bakuman。, upon declaring war on Nanamine, Mashiro tells him that manga is produced by desperate effort by the authors in collaboration with the editor, and they won't lose to a manga that's patched together from other people's ideas.
Later on, Kosugi tells Nanamine just where he went wrong with his manga when he fails in his second and final attempt at getting serialized.
Kosugi: But something was missing, Nanamine, something more important than anything else. In fact, I'd say it's the one thing any story in a shonen magazine can't do without. That would be the heart of your characters. You can never express their feelings if you can't sympathize with others in the first place.
In Blood+, Kai gives David one of these after the latter becomes a depressed alcoholic following the destruction of Red Shield's headquarters. Kai states he isn't as tough as he claimed to be at the beginning of the series.
In The World God Only Knows, Haqua delivers one to Keima for all his manipulations. In a subversion, she doesn't actually mean it, and immediately begins to try and wave her words off when she thinks it might have actually affected him.
Skip Beat!: Near the end of episode 12 Moko delivers an epic one to Erika.
"You've always been a midget, a klutz and a blockhead. Not to mention slow in the head and snow on the uptake... I mean, I knew you were a hopelessly lame and worthless shell of a man, but to peep at me just because you can't get a girl..."
Louise tries one of these on Kazukya in Freezing, explaining why the boy is unfit to be near Louise's sister. It fails.
In Volume 11 of the Zero No Tsukaima manga, after his memories are restored, Saito gives one to Louise:
"What’s so good about you? No one would take notice of you - you are haughty like hell, you kick around when you sleep, you do not wear panties, one only can say 'I love you' to you out of pity for the bust-handicapped girl, really. There’s nothing else to praise you for. When I ignore you, you try to provoke me calling it a familiar's 'reward', but when I misunderstand and drool about it, you put me down with insults. Your head is as much of a zero as your chest is, idiot. Realize the reality, peach-haired fool."
.hack//SIGN features multiple iterations of this trope during the last episode, when Morganna's "shadow" versions of Tsukasa, Subaru, and Mimiru lecture each real version about how worthless s/he is.
Seikimatsu Occult Gakuin: Subverted because Ami gives Fumiaki one in a very casual manner and didn’t think about its significance, but Fumiaki took it seriously enough.
"Inner" Moka from Rosario + Vampire hands out one to Tsukune after getting his ass kicked yet again in training.
"Tsukune, I'll give you my judgement. This is no good at all. You have vampire blood, so you must have the 'aptitude' to become stronger. You were dutiful originally, so you are a fast learner. However...They're light. I'm speaking about your weakness, your fists. The things needed to win, you have no 'will', nor do you have 'killing intent'. So who on earth are you planning to defeat?
Paprika: Chiba gives one to Tokita calling him out on his immaturity and only doing what he wants instead of what needs to be done. This unfortunately and leads Tokita to go into Himuro's dream to figure his motive for stealing the DC Mini. It doesn't go well.
High School D×D: Issei gives one to Shalba Beelzebub the second time he curb stomped him. He claims that Sirzechs and Vali are superior than him because they have what it takes to be a lord of hell, while Shalba just wants to wage war. Take note, Issei is the protagonist here.
Akito of Fruits Basket simply loves handing these out, most notably to Tohru and Kana.
Black Haru to Kyo, often.
Corkus gives Guts some of these in episode 19 of Berserk.
In Mai Hime, Nao gives two to Mai, accusing her of priding herself on being a "good sister" and being overprotective of Takumi and Mikoto. Both of them hit quite hard.
Episode 7, when Mai finds Mikoto working with Nao in luring perverts out for her to rob.
Nao: Plus, I hate people like you. Acting like "I'm innocent, I'm a good sister, I'm having lots of trouble..." I've heard so much of that I'm getting calluses in my ears from listening. "Mai-chan is so great at working hard." You retarded or what? Makes me want to puke.
Episode 20, when Nao calls Mai to taunt her as she plans on harming Takumi in revenge for losing her eye.
Mai: Please stop, Takumi is my-
Nao: Precious brother? Don't you hate him in reality? Don't you wish he would just disappear?
Mai: How could I ever...?
Nao: I wouldn't be so sure about that. You just like being a hard-working sister. Mikoto was saying it too. "I'm always being treated like a kid or her servant." Well, I'm gonna pounce now, deceitful sister. (hangs up on Mai).
Sonic X has Eggman giving one to Chris when he thinks he's lying about not being responsible for the time freeze.
Eggman: You're the one who's lying to yourself. You don't wanna accept the truth. Deep down, you know once Sonic is gone, your life will have to go back to the way it was before. Your days of adventure are at an end, boy, just like your friendship with that hyper-annoying hedgehog. All your dreams have been shattered, haven't they? Life is like that, kiddo. Take it from somebody who knows! Whenever you reach too high, life smacks you down! But on the bright side, at least you and I won't have to see each other ever again.
Kara no Kyoukai movie 5. Araya Souren delivers an dreadfully cutting one to Tomoe Enjou as he kills him, explaining that all Enjou has done was because Araya programmed him to do it, and that Enjou will never accomplish anything due to having an origin of 'worthlessness'. Despite this, and while disintegrating Enjou manages to get a tear-jerkinglast line, saying that despite everything Araya says being true, he "was still here".
Deep in the Arcanum, Muhyo encounters the spirit of Imai's subordinate Fujiwara, and sentences him to the Styx, remarking that if he got killed against a rain dog, he was either incompetent or negligent. The rest of the group comments on his apparent reckless overuse of magical law.
Roji: That was your third sentencing in one day! Isn't that a lot? Have you reached your limit?
Muhyo: Well... what'd you want me to do? Wait for your lousy pen to work? I've had about enough of you. You too, Rio. (to Biko) And how long do you plan on sniveling? Idiots, all of you!
When Page finds Enchu, Enchu is standing over the unconscious body of his old friend Yoichi, and Enchu casually asks what Yoichi is doing there. Page then grows angry, saying Yoichi dedicated two years of his life to finding Enchu even though Enchu was doing so much evil.
Page: A 100-pointpenalty! You say that knowing who lies here? Yoichi... for two years he's given up study and free time. He works tirelessly on the investigation. For you, Enchu. And what were you doing? Forging rotten friendships. Plunging the Association into fear. I visited your mother's grave. But what could I tell her? What could I say about her son? Should I have apologized, maybe? Sorry for not making him an executor?
Sangatsu No Lion: Friend and rival Nikaidou, in his zealous and infuriated commentary of Rei's MHK Cup match, attempts to tell the protagonist Rei exactly why he's been doing poorly in shogi at the time.
In Sakurasou No Pet Na Kanojo, Rita gives Mashiro a scathing one in episode 10, when she rants about how the latter's talent overshadowed all of the other kids in their art class, and eventually Rita's grandfather told her to just give up since she would never be as good as Mashiro. Rita also says she planted the idea of drawing manga as a means to have Mashiro humiliate herself and see what the other kids felt towards her, but is angered to see her having a debut for that as well. She then tells Mashiro she hates her.
In Rozen Maiden, Suigintou delivers one to Jun trying to drive him and Shinku further apart so he can't help her during the fight later. It works, leaving Jun almost suicidal, until Nori finally snaps him out of it.
In one episode of WORKING!!, Souta Takenashi delivers a well-deserved one to Inami's father, who gifted his daughter with one hell of a case of androphobia.