Kyle: Dude, why is your store called the Indian Burial Ground Pet Store? Store owner: Well, there was an Indian burial ground here before I bought it. Stan: So you just built your store on an Indian burial ground!? Store owner: Oh hell no. First I dug up all the bodies, pissed on them, and then buried them again upside-down. Kyle: Why!? Store owner: Why? I don't know. I was drunk.
Captain Haddock of The Adventures of Tintin practically lives by this trope. Highlights include: knocking out an airplane pilot mid-flight for not letting him use the controls, lighting a bonfire in a lifeboat, and exiting a space rocket to try to float back to earth.
In The Laurel Wreath, Vitalstatistix and Obelix both overindulge at a family gathering, prompting Vitalstatistix to make a suicidal bet that he can bring them a stew spiced with Caesar's laurel wreath, and Obelix to enthusiastically endorse this stupid idea until there's no way anyone can back down - slurring "zigactly!" ("farpaitement!" in French). Asterix spends much of the rest of the adventure passive-aggressively using the word 'zigactly' to remind Obelix of how much of a fool he made of himself.
In Asterix in Britain the Roman soldiers are forced to sample hundreds of wine barrels to find one that contains magic potion. The unit starts out perfectly coordinated as they tap open the barrels, drink a little, and move to the next ones. We watch over the panels as everyone gets progressively less coordinated until they're lying in unconscious piles, at which point the Roman who did get magic potion decides to start a fight.
In The Chieftain's Shield a Roman soldier, frequently disciplined for his excessive drinking, is ordered to dress as a Gaul and infiltrate a bar to seek information. As soon as he gets out of his superior's eyes he makes a beeline for the bar, gets hammered and starts talking in Latin phrases, declining his Alcohol Hic as 'hic! haec! hoc!', and complaining about his Centurion, making his disguise so pathetic that the Gauls express a certain amount of pity for him.
Tremensdelirius, The Alcoholic legionary in Caesar's Gift is made of this trope. He begins the story by sneaking off to get drunk the day before his retirement, and, despite being urged to keep quiet so the rest of the army doesn't find him, decides to start singing really loudly. When he gets discovered, he starts badmouthing Caesar. When Caesar, who is preparing land gifts for the retiring legionaries, finds out, he decides to give Tremensdelirius the deeds to the Gaulish village full of super-powered Roman-hating madmen, in full knowledge that when Tremensdelirius goes to claim the land the villagers will make his life a living hell. On his way there, Tremensdelerius gets drunk and swaps the absurdly valuable deed with an innocent innkeeper in return for wine.
In Bloom County, Steve Dallas has a tendency to exhibit this after imbibing too much.
Opus, years later, gets into a scandal when he makes some offensive remarks after drinking too much, parodying the infamous Anti-Semitic remarks of Mel Gibson during his arrest for DUI.
When Farley covered the National Park Olympics, the most popular event was the Get Drunk and Do Something Stupid Freestyle.
Films — Animated
In The Great Mouse Detective, Professor Ratigan congratulates himself on his outstanding villainy and celebrates with his minions. One of them, Bartholomew, gets so drunk that he unwittingly calls his master a rat (which he is), Ratigan's Berserk Button. He takes Bartholomew with him and serves him up to his pet cat for lunch.
Films — Live-Action
At the beginning of Cool Hand Luke, the title character vandalizes some parking meters after imbibing too much. Things don't get better for him afterward.
The Fly (1986 version): In retrospect, Seth Brundle should've waited until he was sober before deciding whether or not to test his matter teleportation device on himself.
The ultimate example against which all others in the canon must be compared is probably Gussie Fink-Nottle's inebriated speech at the Market Snodsbury Grammar School prize-giving in Right Ho, Jeeves.
The Drawing of the Dark, a novel that is, at least in part, about a 16th century bouncer at a bar in Vienna, contains numerous examples, including Duffy, the bouncer in question, starting a drunken barfight to prevent a drunken barfight.
In The Pistoleer, a poker player, Frank, drunkenly accuses another of cheating. The "cheater" asks how he could be cheating, when Frank's doing all the winning. Frank stares at his pile for a second, before saying "Hell, maybe I'm the one's cheating." An observer has no idea how the accused cheater, a decent fellow, got into a poker game with a bunch of violent cattlemen, except that he was drinking more than usual, "which is sufficient explanation for almost any stupidity a man might do."
In the original book of Roald Dahl's The BFG, after the giants are captured and imprisoned in a deep pit, three particularly drunk and silly men decide it's a good idea to climb over the fence keeping people from falling in. They, naturally, fall in, and are equally naturally gobbled down by the ravenous giants.
In Happy Endings, the characters spend, by their own admission "half their lives" in Rosalita's, their favorite bar. But they usually don't get too drunk. Notable exceptions include the episode "Bo Fight", in which Dave, still reeling from Alex pulling a Runaway Bride on him, gets really drunk with Max and they go looking for Bo, the guy she (sort of) ran off with.
On Cheers, recovering-alcoholic Sam suffers a relapse and drunkenly bets a man that if he hasn't married Jacqueline Bisset in one year, he'll let him have the bar. 364 days later, after Sam has long since sobered up and gone back on the wagon, the man shows up at the bar to collect on the bet.
How I Met Your Mother has this all over the place. Ted's apartment is above a bar and they spend a lot of their free time there drinking. From time to time, one or more of them gets really drunk and does something really stupid. Hilarity Ensues.
The "Home Wreckers" episode had a game where the friends had to guess whether Marshal was drunk or a kid when he did something stupid like putting fireworks in the microwave (Drunk) or when he tried to ride his bike down an extension ladder from the roof of a two story house (Kid).
The trope is somewhat inverted on an episode of Monk where Stottlemeyer solves a crime because consuming booze actually makes him more intellegent. He just can't remember how he solved it, and spends most of the episode trying to figure out what he did on his bender while fighting a hangover the next morning.
On My Name Is Earl, many of the misdeeds that Earl is trying to correct involved alcohol.
On the second season premiere of Shameless, the family patriarch is clearly soused when he decides that making a $10,000 bet (when he can barely afford his current booze bottle) is a good idea.
Any time the MythBusters have to get drunk on camera for a myth, hilarity of some kind is sure to ensue. The hangover myth (beer vs. beer and liquor) is a prime example; it includes Tory jumping into bed by climbing the wall outside the bedroom (rather than, you know, using the door to get in).
Don't know the reason I stayed here all season With nothing to show but this brand-new tattoo, But it's a real beauty, a Mexican cutie— How it got here, I haven't a clue.
Myths & Religion
In some versions of the story about the sinking of Ys from Celtic Mythology and French folklore, the Princess Dahut-Ahès gets drunk and opens the dike gate that protects the city from flooding at high tide during a storm.
One quest in The Elder Scrolls V: Skyrim seems to be a Shout-Out to The Hangover. A guy in a tavern challenges you to a drinking contest. After four drinks, you black out... and wake up in the Temple of Dibella in Markarth. You then spend the next little while learning what you did last night due to Alcohol-Induced Stupidity, and trying to fix things. In the end, it turns out you were the victim of an elaborate prank by Sanguine, the Daedric Prince of Debauchery.
This is also the reason a particular inn is known as The Drunken Huntsman. One of the owners, Elrindir, explains that they got the name from an incident where he and this brother Anoriath went hunting after consuming too much alcohol for good measure. Long story short, Anoriath thought his brother was a deer and he was Shot in the Ass with an arrow.
In the Citadel DLC for Mass Effect 3, Shepard has to bail out Grunt with C-Sec after he decided to celebrate his birthday with a wild night out on the Citadel, causing a lot of property damage in the process.
In the 'book-only'Start of Darkness, the second prequel to The Order of the Stick (and labeled as Book #-1), it's explained that this is how Eugene Greenhilt made his Blood Oath of Vengence against Xykon. While searching for information on the sorcerer, many of Eugene's leads were in the seedier parts of Cliffport and he had to buy the lowlifes a round of drinks. He apparently had a few too many himself and ended up wandering into a tattoo parlor that also did rituals.
Yeagar from Nodwick isn't the cleverest person even when sober, but some of his best (read: most disastrous) ideas usually come to him when drunk. One comic features this exchange when Artax is explaining why he has returned from a scouting trip without Yeagar:
Artax: And then Yeagar said those six words that strike terror into my soul... Nodwick & Piffany: "Hold my ale and watch this."
The whole premise of Markiplier's series "Drunk Minecraft". The only conclusion where you get a group of drunk adults playing Minecraft with an admin that's happy to give them whatever they want, provided they don't piss the admin off, which of course they do.
Rooster Teeth and its spinoff Achivement Hunter both fall into this. In one particularly case, Gavin ended up drunk during an episode of their Minecraft playthrough and almost derailed their efforts to complete a difficult achievement, stealing their gold and making a "Tower of Pimps", and assaulting them in-game. He admitted that in hindsight, it was painful to watch.
The Simpsons: happens frequently and is often displayed by Homer (and sometimes his barfly buddy Barney Gumble).
In a flashback scene during "El Viaje Misterioso de Nuestro Homer", Homer, after drinking too much beer at a chili cook-off, decides to take off all his clothes and climb into a cotton-candy machine and pretend he's a "puffy pink cloud."
In an example involving Barney, the "Mr. Plow" episode features a flashback scene where we see a teenage Barney studying for the SAT when Homer sneaks in with a six pack of beer. After Homer pressures him, Barney reluctantly agrees to take a drink and, with one sip, we actually see his IQ drop sharply.
Parodied in "Boy-Scoutz 'n the Hood", where Bart and Milhouse go on a squishee bender. The next day, Bart discovers he's joined the Junior Campers, and Milhouse has a dirty word shaved into the back of his head.
In "Deep Space Homer", Barney, when selected by NASA to be an astronaut, swears off alcohol and successfully completes his training program with flying colors. Unfortunately, when he takes a sip of a congratulatory glass of champagne, his face immediately reverts back into its permanently soused expression as he proclaims, "It begins." He then steals a jet pack and careens drunkenly through the sky until it runs out of fuel, causing him to crash onto a pillow factory roof and bounce onto the street below where he's run over by a marshmallow truck. The fact that it was non-alcoholic champagne says something about Barney's alcoholism.
Brian from Family Guy tends to be the voice of reason in the Griffin family, but whenever he gets drunk he will often do something incredibly stupid. Odds are, Peter will be right along with him.
The Darwin Awards would likely cease to exist, or at least lose a significant portion of their content, were it not for this trope.
Several relatives of Darwin "winners" protested the deceased being mocked on the site, on account of their judgement being impaired by alcohol. The Darwin Awards judges replied that those people made the decision, conscious and sober, to impair their judgement with alcohol in the first place.
Fark.com also subsists on a diet of "Why, yes, alcohol was a factor" headlines. When this intersects with the Florida tag, it gets truly bizarre.
During his career of being the first and only person to ever routinely drunk drive a superpower, Boris Yeltsin managed to unfortunately combine this trope with Vodka Drunkenski on more than one occasion. One of his most infamous examples being when he visited President Bill Clinton in Washington, DC. The trip pretty much ended when Yeltsin drunkenly stumbled out of Blair Housenote The official guesthouse for foreign leaders come to call on the President, right across the street from The White House one morning and tried to hail a cab because he wanted some pizza. On Pennsylvania Avenue. In his underwear.
Part of what made The Wild West so wild was that there was that in every town, bored cowboys, depressed miners and celebrating gamblers had a ready supply of booze in the form of the local saloon. The other thing they had plenty of cheap and affordable access to were firearms. A few too many drinks convinced many a would-be gunslinger that the best response to a perceived insult was to shoot the other guy's head off.
Everything that comes after someone saying, "Hold my beer and watch this." (A statement known in some circles as a "Redneck'sFamous Last Words.")