Sandbox / Monster: Anime & Manga (C to F)

All spoilers are unmarked. You Have Been Warned!

C

• Cage of Eden: Takashi Nishikori crash-landed on an island along with hundreds of other passengers and established his power over them by blackmailing them into serving them, only offering them an antidote to a lethal plague with which they had all been infected if they do so. Killing anyone who threatens his power, Nishikori responds to a confrontation with Akira Sengoku's group by torturing them before sending them on a Suicide Mission. Capturing all the female members of Akira's group, Nishikori forces the males to try to rescue them, while intending to execute one girl for each failed attempt. Trying to force the girls to sentence one of their own to death, Nishikori promises his men they can gang-rape the survivors.
• Captain Commando, by Kenkō Tabuchi & Kotomi Tobashi: Scumocide has his character fleshed out into that of a Social Darwinist who seeks to conquer the world. In the past, Scumocide led his self-named organization in crusades that lead to the destruction of Zurch and Venice, as well as the deaths of everyone in the 7th Armada of the U.S. Navy Fleet. When Alexander Carlisle got involved with Project Tri-Haniel, Scumocide had him and his wife murdered, leaving a young Mars orphaned years before he became Captain Commando. In the present day, Scumocide seeks to conquer Metro City as part of his conquest, leading to millions of lives at risk of being lost. He also has no issue allowing cronies to die when he no longer sees any use in them.
• Case Closed (aka Detective Conan):
  • "Old Blue Castle" case: Mutsumi Nishikawa was a maid working for the Mamiya family who became obsessed with finding the treasure the family patriarch left in his castle. To this end, Mutsumi set fire to one of the castle's towers to fake her death, killing over a dozen people, and then killed and impersonated Masuyo Mamiya. When a man was hired to investigate the tower, Mutsumi starved him to death and dumped his body in the woods. When Professor Agasa and the Detective Boys arrive at the castle, Mutsumi stalks and attacks them, gloating about her plan to starve all of them to death so they wouldn't get between her and the treasure.
  • "Metropolitan Police Detective Love Story III—The Case of Masayoshi Sato": The unnamed arsonist is a gleefully sadistic man who desires to "light up" Tokyo with flames. Before the events of the case, the arsonist started several fires across the city and also stabbed an innocent man to death. When witnessed starting another fire by the Detective Boys, the arsonist tries to kill them with a smile on his face. After his arrest, it is revealed that the arsonist had planned to blow up a fuel warehouse and burn the entire city down in a "beautiful carnival" of flames.
• Cerberus: Nanbuko in the anime is an Arms Dealer who helps to keep things worse for the countries by both starting and supplying the wars with his weapons. Obsessed with the dragon Dagan Zod, Nanbuko sabotaged an attempt to defeat the dragon for good years ago, killing all of his comrades there, intending on allowing Dagan Zod to kill countless people to create enough chaos for him to profit off of. Nanbuko then attempts to kill all his followers by reducing them to raw magic, betraying even his loyal right-hand woman before gleefully trying to take Dagan Zod's power for himself to spread the "beauty of destruction" personally.
• A Certain Scientific Railgun:
  • Kihara Gensei, the patriarch of the Kihara family, is responsible for nasty experiments on children, which resulted in many of them suffering permanent trauma, all so that he could create a powerful Level 6 Esper. Gensei has no compunction murdering people in his path. The first "sample" of his experiments was his own granddaughter: Gensei overloaded her mind to collect samples from her, and repeated this process on other children as well. Gensei was fond of manipulating his own family members into becoming his test subjects, even though he knew that a massive surge would possibly destroy all of Academy City.
  • His granddaughter, Therestina Lifeline, is just as cruel and twisted. Wanting to follow Gensei's example, Therestina abducted children and put them in comas so she could harvest the samples from their minds. Gensei manipulated the young heroines into providing cover for her, all the while intending to overload the minds of the children she kept under sedation, fully aware this would destroy all of Academy City and not caring as long as she achieved the "perfection" she hungered for.
• Chainsaw Man's "International Assassins" arc: The Doll Woman, also known as Santa Claus, is an assassin out to seize the powers of the Devils. With her power to turn humans into dolls while erasing their minds and personalities, the Doll Woman converts countless people over the world into her puppets while utilizing an old man to adopt orphans so she can raise one as a perfect puppet and sacrifice the others for a Devil contract. Coming to Japan, she converts many people to dolls to attack hero Denji and gleefully attempts to plunge others into hell for a new Devil contract.
• Chaos Dragon: Lady Kohkaku, a sadistic general for the Kouran nation, kidnaps male children she finds attractive—possibly raping them—before killing them, absorbing their souls to extend her life. When her forces are attacked by rebels in a village, she has her men shoot through the villagers while fighting. After discovering Ibuki is hiding in the same village, Kohkaku returns to raze the whole place, personally setting fire to an orphanage in the hopes the screams will draw out her foe.
• Cheat Slayer: Louis Crawford, "God's mistake", is a perverted sadist who believes the new world exists only for the amusement of reincarnates. As a member of the corrupt Rebels Against God, Louis uses his cheat powers to kill random people and rape any woman who catches his eye. He destroys Lute's home village and rapes his friend Lydia to death, almost killing Lute in the process. When he encounters Lute again, Louis tries to kill him again to Leave No Witnesses to his crimes.
• Chimamire Sukeban Chainsaw, by Rei Mikamoto:
  • Nero Aoi is a Mad Scientist who serves as the series villain. A previous victim of bullying due to experimenting on animals, Nero decided to take over the world by killing off her classmates and configuring them into an army of remodeled corpses. She creates a serum that causes people to become insane and violent, and keeps her childhood friend Yuto around as a pet to molest and mentally torture. Resurrecting herself, she converts the Volunteer Club into the Guardians, a group of knight templars who kill anyone suspected of sin. Kidnapping Kimberly to lure Geeko and company to her lair, she has them pitted against previously-deceased murderers and forces them to kill a crazed, out of control Kimberly that results in the death of Mizushima. Once again resurrecting herself, she partakes in the Mondokanoke prison where her remodeled corpses are tortured, and later hunts down Geeko and Bakutani once they escape, where she ends up killing Geeko and attempts to resurrect her as her most powerful fighter. Obsessed with fueling her own ego, Nero stood out in this twisted world as a selfish psychopath hated by all.
  • Final four volumes: Mari Fuwa is the warden of Mondokanoke, an all-female prison for remodeled corpses. Believing that she can do whatever she wants as the warden, Fuwa creates a festival where she invites rich clients to watch her prisoners engage in grotesque sexual acts and deadly Gladiator Games for their viewing pleasure. Having Geeko imprisoned in order to compete in her gladiator games, Fuwa at one point as Geeko stripped naked, crucified, left out in the cold rain, and whipped after she kills one of her prized prisoners, doing the same to Bakutani after she refuses to partake in the erotic show. Regarding her prisoners as "fools with no hope of a future", Fuwa has them hunt down Geeko and Bakutani in return for their freedom, allowing some bounty hunters to infect them with a gas that makes them kill-crazy.
  • reflesh: Mirei is the true head of the St. Argento Academy. Posing as the academy's student council president, Mirei lures in young girls and remodeled corpses to the academy, where she has them killed to either bathe in their blood or store it in bottles to drink in order to gain power. After Geeko's arrival inspires many first-year students to escape, Mirei personally executes them, laying their naked corpses out in a pile for everyone to see. Desiring Geeko's blood for herself, Mirei uses her tentacle hair to decapitate one of Geeko's friends, before trying to kill Geeko herself.
• Choujin Sensen:
  • Hitsugi Morio, one of the Espers, was a blind doctor granted sight by FEE. As a doctor, Morio became obsessed with handsome young boys and butchered one on his operating table. Becoming a depraved Serial Killer, Morio hunted down, abducted and dissected numerous young boys between the ages of 6 and 18, preserving their corpses for his collection with the intention of claiming more once his sight returned. Upon facing the martial arts expert Yue, Morio gleefully intends to kill him and add him to the collection, even murdering an innocent doctor when Yue goes for treatment, showing himself as the worst of FEE's chosen fighters.
  • Isaac, Sir Isaac Newton himself, is a member of the Carbinoids, the team of FEE's rival, MATE. He is the most depraved of his team, announcing himself by causing a disaster in Tokyo that kills countless innocents, including the parents of the Tomobiki Rinji, just so he can issue a challenge. In his fight with Rinji, Isaac shows himself to be a violent sadist, torturing Rinji with his powers and even causes Mt. Fuji to erupt without a care to the devastation it causes. Isaac is also gleefully on board with his leader Leo's scheme to kill 95 percent of humanity, without any of Leo's noble goals, and when defeated, he attempts to drag Rinji into the volcano with him.
• Choujin X: "War Choujin" Queem Macman was a vile Choujin X who used his powers to launch a military coup and become President of Guelta. Starting the Great Choujin War, Queem personally advanced weaponry, and, hell-bent on conquering the world, forced his Choujin troops to painfully Raise themselves from death unendingly. Using enemy territories to hunt for sport, Queem massacred civilians and conducted religious purges, the horrors of his crimes fracturing human society, which is still healing even 70 years after his death.
• Chrono Crusade (2003 anime): Aion is stripped of his original counterpart's redeeming qualities to become a remorseless seeker of ultimate power. Having decapitated the leader of Pandemonium, Aion uses her severed head in his ritual and sparks a war in the demon world that kills countless millions. Tearing off the horns of fellow devil Chrono for showing remorse, Aion bestows them upon the young Joshua Christopher, uncaring that they drive the boy mad and lead him to petrify everyone from his orphanage. Taking advantage of a lonely woman, Aion manipulates her into killing an entire town of people as a sacrifice to him, delighted in the control he holds over others. Conducting his ritual for godhood, Aion nearly destroys San Francisco, and when Joshua's sister, Rosette, seemingly stops him, reveals it was her powers he wanted after all. Brainwashing her into becoming his slave, Aion entrances civilians with her healing powers before declaring himself a prophet who has deemed humanity sinful and demands they kill each other. With a plan that will bring about the apocalypse, Aion cares nothing for the billions who will die as long as he gets what he desires.
• The City of Imprisoned Love, by Kyohei Tawara: Tanisako Natsuki is one of the administrators of the virtual reality containing a false Japan. A ruthless exterminator of anomalies and enemies of the system, Tanisako also uses his powers to indulge in his God complex and shut down the senses of his victims to mutilate them and throw their still-alive bodies into a small room that Tanisako calls "Hell" to suffer a slow death while keeping dozens of severed heads of his victims near his house, punishing obedient servants alongside rebellious ones. When the heroine Yukiko tries to interrogate him, Tanisako shuts down her senses to leave her to die and mocks her friend Makoto when he tries to rescue her before trying to inflict the same fate on him.
• Claymore:
  • Rimuto is the head of the Organization and the one responsible for its inhumane activities. Rimuto has orphans taken by the Organization, turning the boys into inhuman monsters, either Yoma or Awakened Beings, while the girls are turned into Claymores. The lifespans of Claymores are typically short, either dying or becoming monsters themselves to perpetuate the cycle, with Rimuto having countless killed to keep their operations going. Utterly unconcerned with his test subjects, Rimuto even states warriors who die quicker are best, and when villages refuse to pay the fees, Yoma are sent to wipe them out completely. Throughout the course of the series, Rimuto keeps his warriors as disposable cannon fodder, conducting awful experiments on innocents while being wholly unconcerned with all who die in the crossfire.
  • Roxanne of Love and Hate, a former "Number One" of the Organization, differs from most other villains in the series by being an outright cruel and violent sadist. Initially a low-ranking warrior, Roxanne rose up the ranks by seducing/befriending and eventually murdering stronger warriors after stealing their techniques. Eventually, she set her sights on the existing Number One Cassandra, but when she saw Cassandra's technique, she decided it was unsightly and gave Cassandra the hated moniker "Dust-Eater." She later set up Cassandra's only friend to die a torturous death at the hands of an Awakened Being and mocked Cassandra by saying that her friend had looked as if she had "enjoyed" being played with by the monster, so interfering wouldn't have been right. Cassandra snapped and attacked her. Roxanne used the other 45 warriors as shields, relishing in their fear of Cassandra and cackling at how hideous Cassandra's abilities were. When Cassandra finally reached Roxanne, Roxanne gleefully impaled her head with the pommel of her sword, a technique stolen from her first victim.
• Code Geass franchise:
  • Lelouch of the Rebellion:
    • Diethard Ried is a Britannian journalist who joins the rebel Black Knights to sate his need for bloodthirsty excitement. Becoming the most brutal of Lelouch vi Britannia/"Zero"'s inner circle, Diethard uses his media connections to manipulate battles in their favor, caring nothing for the civilians caught in their many fights and even smiling as he broadcasts one particular massacre. When Lelouch forms a territory of united nations Diethard immediately takes the opportunity to push for a global war. Ultimately betraying Lelouch to his brother Schneizel, Diethard assists the latter in his plan to use super weapons to terrify the planet into peace, Diethard himself only interested in the bloodshed caused along the way and overjoyed to get to witness the results of Scneizel's annihilation of Pendragon and the millions of citizens living there.
    • Seasson 2—R2: Alicia Lohmeyer is a cruel Britannian bureaucrat assigned to be Nunnally's aide and advisor, who uses her position to constantly make things worse for the Japanese living in Sector Eleven. Always trying to subvert Nunnally's compassionate ways, Lohmeyer reacts to one million Japanese trying to secede from Britannia with Zero's help by ordering them all be massacred in a sadistic, xenophobic fury, willing to fire the first shot herself and insulting loyal Suzaku's racial heritage for defying her. Lohmeyer later goes behind Nunnally's back and orders the prisoner of war Kallen be executed, purely out of spite for Nunnally befriending her.
    • R2: Luciano Bradley is the most despicable member of the elite Britannian Knights of the Round. Joining the group solely so he can kill combatants and civilians alike, Luciano is implied to be deployed out to war zones for the sole purposes of "purging" lower classes, a task he takes to with pure gusto. Luciano informs a captive female Japanese soldier how expendable she is before attempting to rape her. Participating in an assault on Japan, Luciano plans to massacre Tokyo as much as he can, happy to murder his own men if they get in his way while slowly and agonizingly dismantling any enemy he finds while taunting them about valuing their lives.
  • Renya of Darkness prequel:
    • Chapters 15-22: Lord Aaron is a vile Nova Hispania conquistador who enslaved the residents of the Philippine Archipelago after lying that he came in peace. Aaron has wiped out entire villages, personally tortures and executes whatever dissidents he can get his hands on, and captured a rebel's fiancée so he could turn her into a mindless Knightmare and have her kill her old beloved and his friends.
    • Chapters 24-26: Barbaros is the Britannian Knight of Thirteen who supports Lorenzo il Soresi's war across Britannia's nations. The former executioner, Barbaros used the guillotine with glee, even murdering children for being family of traitors. Sent to capture a Britannian princess for Soresi, Barbaros plans to mutilate her to make her a submissive puppet ruler, kill all of her companions, and bring scores of female captives back to the mainland to sell into sexual slavery.
  • Akito the Exiled: General Gene Smilas is a seemingly supportive commander of Leila Malcal secretly plotting his own coup. Playing Leila and her fleet of young Japanese soldiers, Smilas makes a deal with the insane Euro Britannia commander Lord Shin Hyuga Shaine to allow media attacks to drive the European Union to near-collapse before sending him Leila to kill while he announces her death to use the unrest to become Emperor. Utterly apathetic to Shin's desire to nuke the Britannian capital and readying his forces to crush any question to his reign, the universe's God itself dismantles Smilas's claims of good intent, revealing him to be a selfish coward under his words.
• Cop Craft anime:
  • Zelada is an extremist who uses acts of violence to incite hatred between humans and Semanians. Initially unseen, Zelada frequently uses the "latena" of fairies to kill others and enslave them as controlled corpses. Introduced posing as a subordinate of the smuggler Dennis Elbaji, Zelada demonstrates a prototype for a "fairy dust" bomb on two police officers. Confronted by San-Teresa Police Detectives Kei Matoba and Tilarna Exedilica—the former of whom recognizes Zelada for slaughtering his platoon when Kei was in the military—Zelada exploits their superior's xenophobia in order to escape to the roof of a skyscraper where he intends to amplify his bomb's blast radius. Seemingly dying by falling off the roof—with his bomb having been defused—Zelada eventually reveals himself to still be alive, having planned the assassination of two mayoral candidates in order to install his own puppet and increase tensions between humans and Semanians. Upon capturing Kei and Tilarna, and killing a reporter who met up with them, Zelada claims to be acting in the best interest of the Semanians, but is called out for his cultural posturing and xenophobia by Tilarna before Kei shows up to confront him.
  • Dennis Elbaji is head of a "fairy dust" manufacturing ring who hides behind his role as an up-and-coming nightclub owner, having abducted over a hundred fairies to manufacture his product for his own personal gain. Introduced having the sorcerer Zelada test a fairy dust bomb on police officers, Elbaji makes Zelada toy with the corpses before having one corpse shoot both. Confronted by Tilarna in his nightclub after harassing her, Elbaji tries to have her shot once he realizes she is on a rescue mission. Subsequently defeating her in a sword fight, Elbaji takes Tilarna prisoner, professing to worship money on the drive to his facility. Later setting his facility ablaze, Elbaji makes a callous quip about how much the fire will cost him when he encounters Tilarna again. Defeated in a final duel thanks to Kei's intervention, Elbaji defiantly curses Tilarna out.
• Coppelion: The unnamed Three Profesors are a trio of sadistic mad scientists controlling the Coppelion program. Having forced the Dr. Coppelion into exile, the Profesors uses the infant Coppelions for torturous experiments—including the Ozu Sisters, being the real cause behind their violent behavior—while getting rid of the flawed ones by killing them. Intending to capture the ultimate Coppelion Aoi Fukasaku in order to use her to create more, the Profesors kidnap Shion Ozu to torture her and use her as a hostage alongside the remaining survivors of Tokyo. When Aoi gives herself to save them, the Professors attack and kidnap her while keeping Shion. After they escape from their ship, the Profesors send the Lost Retrieval Unit to capture them without care for the survivors while constantly threatening to kill the Retrival Unit if they dare to rebel. Killed for a freed Retrieval Unit, even Kanon Ozu herself is surprised at realizing that behind their masks, they were just normal old humans.
• Cosmo Samurai: Jaaku is a being of darkness responsible for the Cosmo Samurai's backstories. Leader of the Akutou Space Pirates, allowing them to pillage and murder everything in their path, Jaaku, upon the Akutou's defeat, dismisses his men as pawns and kills his pet to threaten the Cosmo Samurai. Stealing TOM's body, Jaaku opens a space-time portal and heads to Edo Japan, where he kills the country’s shogun and instigates a war between the country and his shadow ninjas, which leaves three survivors.
• CosPrayers: Princess Takitsu, while initially portraying herself as a benevolent daughter of Goddess Amaterasu, is actually the evil goddess known as "The Woman of the Night" who was sealed away. To get free, she manipulates the heroes to destroy the "Black Towers" that binds her under the pretense that her mother was sealed by the towers. After the towers are destroyed and Takitsu regains her true form, she then attempts to destroy the world.
• Cowboy Bebop:
  • Vicious rose in the Red Dragon Syndicate from a young hitman to their most feared, dangerous member. When his best friend Spike Spiegel and girlfriend Julia have an affair behind his back and plan to leave the Red Dragon, Vicious gleefully takes the opportunity to try to force Julia to kill Spike, lest he murder both. Spike and Julia flee the Syndicate, while Vicious, who believes the Red Dragon should continue its days of gang wars and bloodshed, remains to grow more powerful and plot revenge, luring Spike out by killing their old mentor through massacring a peace summit the man was attending. Later on coldly killing a man he betrayed and left to be arrested for Vicious' own crimes, Vicious also sets in motion his plot to take over the Red Dragon, having the current heads murdered in a firefight alongside their loyalists. Gathering the survivors under his iron-fisted rule, Vicious uses them as pawns to lure Spike out for one last battle, caring nothing for the countless killed as Spike attacks their headquarters, nor Julia's death by his men attacking Spike.
  • "The Van", Wang, Sou, and Ping Long, are the seldom seen yet sinister ruling triumvirate of the Red Dragon Syndicate. Over their long rule, the Van maintain a policy of executing any who attempt to resign, and when Vicious kills their loyal capo, merely arrogantly assert their dominance without showing any care. When their soothsayer indicates Vicious finally intends to turn on them, the Van opt to capture him alive and make an example of him by having him publicly executed within the Red Dragon headquarters, murder his entire faction and even gunning down innocent civilians who so much as knew him.
• Crime and Punishment, by Osamu Tezuka: In this Lighter and Softer adaptation of the famous novel, Svidrigailov remains a dark reflection of Rodion Raskolnikov but with none of the redeeming qualities of his original counterpart. Re-imagined as a communist rebel convinced of his own superiority as an Übermensch, Svidrigailov murders a landowner and mockingly smirks at the cops for failing to find enough evidence to arrest him. Seeing a kindred spirit in Raskolnikov, Svidrigailov attempts to recruit him to the People's Liberation Army, and tries to murder the boy for rejecting his offer. Leading the takeover of St. Petersburg during Red October, Svidrigailov oversees the massacre of civilians with nothing but glee, laughing as homes are torched and explosions destroy the city.
• Crocodile Precinct:
  • Second arc: The unnamed warden is a cruel, sadistic woman who appears oddly youthful. Running her prison with an iron fist, it is soon revealed the reason for her youth is that she drinks the blood of beautiful woman whom she tortures to death. When the heroine, police officer Mika Hino, is captured by her after instigating a riot, the warden has her men fire into the crowd, not caring if her own guards are killed, and subjects the surviving women to torture by stripping them nude and forcing them to stand in place through the hot sun or freezing rain until they collapse. Mika herself is taken to the warden's torture chamber and subjected to torture, with the warden throwing vinegar on her wounds to wake her should she pass out. The warden then has her attendant try to rape Mika, who gets the better of him and escapes. Her response is to furiously execute the man and promptly demand the guards recapture Mika. Responsible for turning her prison into a hell on Earth, the warden lived for two things alone: to remain beautiful and young, but primarily to cause pain to others.
  • "The Savage Chimney Island" arc: The unnamed police officer, known as "The Shadow Man", who rules the titular island, has enslaved the villagers and the island with violence and threats. Seeking to mine gold from below the island, the Shadow Man has men and women kidnapped, abusing them horribly, but allows the men to have "play time" where they can rob and pillage around the island at will. Any who try to escape are murdered, with four victims washing up near the mainland, Mika barely evading sexual assault at the hands of the Shadow Man's men when she arrives on Chimney Island. She soon sees the abused, mistreated slaves, with the Shadow Man indicating he plans to dispose of all of them when they serve their purpose.
• Cross Ange:
  • Prince Julio Asuka Misurugi, heroine Ange's evil brother, betrays her at a ceremony to expose her as a "Norma"; Normas are humans without magic who are shunned and sent to become glorified cannon fodder in a war against interdimensional DRAGONs. This results in the death of their mother. Julio has their father arrested and promptly executed to seize the throne himself. He manipulates their crippled sister Sylvia into baiting a trap for the now battle-hardened Ange, so Julio can capture her, torture her and murder her himself. When she escapes, Julio, taking advantage of a proposal from the mysterious Embryo to destroy and recreate the world, eagerly decides to simply "purify" the Norma, regardless of age, and launches a brutal attack on their home of Arzenal to kill all of them, including Ange.
  • Embryo, the "Creator" of the world, was a scientist who grew tired of warfare and kidnapped the mighty DRAGON Aura to power the creation of a new world. Embryo creates a system where those without magic are oppressed and used as Cannon Fodder to kill DRAGONs trying to recover Aura, while discarding and recreating humans when they fail to impress him. Embryo seduces many of the pilots to his side, using Salia sexually while lying about how he loves her. When Ange herself refuses his advances, Embryo tortures her by forcing her mind to undergo overwhelming pain and then physical need. When Ange tries to escape, Embryo shows his true colors by taking over the mind of her faithful maid Momoka and even tries to fatally shoot Momoka when she resists. Upon the final battle, Embryo simply decides to obliterate all of humanity again, coldly rebuking one of his subordinates for caring about others, and tries to sacrifice his loyal followers to buy himself time. When he is through trying to seduce Ange, Embryo tries to beat and rape her before trying to kill her for not "accepting his love."
• Cyber Blue:
  • Elder Rozalie is one of the most wicked of the Elders, helping to mastermind Earth's President's assassination to sow chaos for him to take advantage of. Upon his reveal, Rozalie orders his own men to kill themselves in order to conceal his identity before revealing his desire to eradicate the free will of every human being on Earth to conquer it. To gain an advantage over Blue, Rozalie tries to murder a group of children, unless Blue will kill himself first.
  • Gaza is the final Big Bad of the series and the vilest Elder of them all. Responsible alongside the others for turning the planet Tinos into a dystopian hellhole, Gaza earns his credentials by experimenting on thousands of innocent people to turn them into augmented "bio-beings". Most subjects die and are thrown away as trash; those who survive are either employed as killers or inducted into Gaza's personal trophy collection. Gaza murdered his own brother to force the latter's lover to become his Sex Slave, and is so devoid of empathy that he murders the other two Elders and decides to take over Earth all by himself after Rozalie dies.
• Cyber City Oedo 808: Shuzo Saionji is a ruthless corporate mogul obsessed with immortality. To this end, Saionji had countless innocents taken and subjected to horrific genetics experiments in a quest to find the secret to eternal life. Only one woman survived, mutated into a vampire-like being. Seeking to acquire her secrets for himself, Saionji had his collaborators murdered and later uses his new knowledge to turn himself into a young, healthy vampire as well before trying to murder his past victim who has come to revenge by draining her entirely of blood to gain her strength.
• Cyborg 009:
  • Skull (or Skarle, Scar, Scarl, or Sekar) is the leader of the Black Ghost organization. He and his men exploit ongoing wars as way to make money by selling their weapons to both sides. In order to complete Black Ghost's "Cyborg Soldier" program, Skull sends his operatives across the world to kidnap people, taking them away from their families and friends so they can be forcibly experimented on. As a way to show off Cyborg 0013's capabilities, Skull has the cyborg rampage across Tokyo, causing massive damage and endangering the lives of countless people all so he can create a spectacle for his investors. Skull later escalates the Muamban Civil War by dealing weapons to both sides of the strife, planning to expand the conflict into other countries simply so he can sell more weapons. Skull is also a user and abuser of his minions, and he will kill his underlings for reasons ranging from failing him to simply being of no more use to him. His primary goal is to provoke another World War just so he can deal more arms and make more of a profit. Skull is ultimately someone with an utter disregard for human life, only caring about the sales of his weapons.
  • (Claus/Klaus, originally Director) Van Vogt (or Van Bogoot or Ban Bogart/Van Bogart), Skull's second-in-command, is a Black Ghost executive who poses as a businessman to cover his exploits. Van Vogt forcibly converts three of Joe/Cyborg 009's childhood friends into cyborgs and sends them out to murder him. When they can't bring themselves to kill their old friend, Vogt activates the bombs he planted in them to punish them for their failure. He later invades the Yomi Kingdom with an army of robots. While liberating the Pu'Awak people from the oppressive rule of the Zattan, Van Vogt's regime proves to not be much better, as he forces the Pu'Awak to work on Black Ghost's ultimate weapon, the Demon Statue. He mindwipes Helen, one of the five Pu'Awak princesses, so he can use her to infiltrate and destroy the 00 Cyborgs' home. One the mission has been accomplished, Vogt leaves her for dead. When Helen and her sisters get fed up with his rule and help the 00 Cyborgs, Van Vogt mercilessly kills all five of them.
  • 2001 anime: Dr. Gaia is the top scientist of Black Ghost and the creator of the Mythos Cyborgs. An old colleague of Dr. Gilmore, Gaia and Gilmore disagreed on the concept of human emotions, with Gaia believing them to be a weakness while Gilmore thought they gave people strength. Setting up base on Magma Island, Gaia activates his Mythos Cyborgs and convinces them that they're actual Greek Gods who have returned to punish humanity for their sins and create a better world. Gaia then sends them across the world to cause disasters affecting hundreds of people so he can gather energy for his generator. When Artemis begins to doubt the Greek Gods' mission and leaves, Gaia fatally shoots her to prevent her from possibly interfering with his plans, even though she showed no intention of standing in the Mythos Cyborgs' way. Even as Magma Island collapses as a result of his generator overloading, Dr. Gaia refuses listen to reason, instead declaring that he can use his generator to become a god. In the end, Gaia is shown to not care about anything other than proving that his cyborgs are better than Gilmore's and becoming a god.

D

• Dairugger XV: Caponero is the supreme commander of the Galveston forces. A jingoistic, glory-hungry sociopath, Caponero ruthlessly prosecutes his war with Earth to kill humankind until the world submits. Undermining his peaceful rival Telesu, Caponero keeps the war going no matter how many of his own die in the process. When the war turns against the Galveston forces, Caponero resorts to wiping out entire planets so Earth cannot liberate them and proceeds to starve his people to funnel all resources into a losing war. When he realizes the war is at its end, Caponero tries to flee, leaving his entire race to die.
• Damned, by Masanori Kadowaki & Tetsuya Saruwatari: Ryoga, Todoroki Jin's long-lost friend, turned out to be something far worse. After Jin tries to save the latter from his second execution, the latter responded by stopping Jin's heart. After he willfully sold himself to Tokyo Company and become one of the top employees, Ryoga used the slaves that the Tokyo Company kidnapped for his own twisted immortality experiment by stitching their dead bodies into a huge giant and change their neurons so that they could ended up becoming a killing machine while keeping their consciousness alive. Ryoga then proceeds to cruelly tell Jin that the friendship he formed in the past was fake and Jin was nothing but his spare parts. After Jin spares Ryoga, the latter then taunts Jin that he will continue his experiments. Before the final confrontation, Ryoga threatens the secretary to give him the whereabouts of the CEO and then blows his head off after saying that the CEO has interested in Jin, and kills anyone who tries to stop him from meeting the CEO. Although having numerous redeeming qualities in the past, Ryoga is revealed in the present to have become nothing than a hyper-human sociopath who tries to rule Tokyo as a god.
• Dance in the Vampire Bund: These are the worst foes that Wilhelmina Vlad "Mina" Tepes, Akira Kaburagi Regendorf, and their allies face in the dark world of the titular Bund:
  • Duke Ivanovic is the most vicious and unhinged of the three Lords. After believing Mina's mother had married a commoner, Ivanovic and the other Lords had her murdered out of spite and jealousy and later committed a worldwide purge off all other vampires to put the world under their control. Ivanovic was once Grigori Rasputin, and drove Russia into chaos and ruin, even later trying to enslave and rape Duchess Anastasia till Mina saved her. In the present, Ivanovic plays a game with the other Lords where they hunt Mina's lover Akira for fun and repeatedly subject Mina to a degrading chastity test. Eventually Ivanovic launches a brutal attack on the Bund to capture Mina for his own pleasure. Once there, he deliberately targets civilians, and has the innocent fangless vampires executed to draw Mina out of hiding intending to eventually wipe them all out. He also uses as shock troops werewolves that he's tortured into feral beasts that have forgotten their own humanity. Ivanovic at points attempts to rape Mina when he can and has a disturbing taste for young girls, not caring that Mina is in her younger body as opposed to her adult form; even declaring he'll only enjoy her adult body after he's had his pleasure of the younger one.
  • Rozenmann, the most elegant, handsome, well-dressed, and polite of the three Lords, is also the most intelligent and manipulative. He tricks Ivanovic into invading the Bund, knowing the death and destruction that will result. Planning for his fellow Lord's death, Rozenmann set up Mina to be kidnapped and replaced by a doppelganger whose terrorist attacks he was secretly financing and patronizing. With Mina in his hands, Rozenmann has Akira (supposedly) killed solely to break Mina further, and injects her with a drug to freeze her in adult form to rape her later. While Ivanovic is a wild, furious warlord, Rozenmann manipulates nearly every bad thing to happen in the series, with nary a care as to the many innocent lives or mental trauma he leaves behind him in his quest of domination.
  • Volume 10: Gabe is a New York vampire crime boss sworn to Rozenmann who makes the most of his limited time. He is a pedophile and maker of child pornography who routinely taunts a stripper about paying a visit to her daughter Susy, who can't be more than six. After he learns the stripper is sheltering the runaway Mina, Gabe violently murders her friend and storms her apartment, immediately noticing how Susy is prettier than he imagined and attempting to seize her before Mina stops him. Gabe uses Susy and her mother as hostages so Mina surrenders under promises they won't be harmed. While Rozenmann's honorable werewolf retainer Gerhard is willing to give the assurance, Gabe makes it clear he has zero intention of not coming back for Susy.
  • Dive in the Vampire Bund Volume 2: Radovan Elichenko in life was a Serbian war criminal who, during the Bosnian wars, led his soldiers into a village while the men were away and slaughtered the elderly and the children. The women suffered worse. Any woman in their teens or over were taken and subjected to endless rapes and tortures. To escape justice, Elichenko became a Cudoviste, or monster in the Slavic tongue—a vampire. He then joined Lord Ivanovic and carried out "purges" of any leftover clans in Ivanovic's territory. After fleeing to the Bund and betraying Ivanovic to gain sanctuary, Elichenko was confronted by the father of one of his victims who had become a vampire to hunt Elichenko down. When presented with a picture of the girl he'd raped and tortured, Elichenko sneered he'd done "thousands of Bosniak sluts" and only remembered them by how they looked "down there" before mocking him about having probably slept with his daughter because "Muslim men love to control their women."
  • Memories of Sledgehammer side story: Friar Bolton, the leader of a secret order of vampire killers once employed by the Vatican, murdered his more reasonable superior to take over the group. When a journalist who knew the truth fled, Bolton had him viciously tortured and nearly murdered Reiko, the man's daughter, to make him talk before Inspector Seiji Hama saved her. When serving as aide to a Colombian politician, Bolton empowered cartels to commit crimes over the country and kidnap his own employer's daughter with no intention of returning her alive. When Seiji saved her as well, Bolton had him captured and tortured by the cartel with his limbs removed, his eye and ears gone and his skin flayed before he was recovered by the vampires and placed in the Artificial Beastman project to heal him. In the present, Bolton engineers a series of terrorist attacks with no regard for collateral damage and violently whips his best agent, his predecessor's daughter Clarissa, with intent to send her on a suicide mission to dispose of her. When he faces Hama, he finally attempts to murder the man himself, along with Reiko when she intervenes. When Clarissa fatally poisons him, Bolton uses the last moments of his life to rant about how only he has the vision to see the extermination of all who stand against his ideals and how her father was too weak to see it.
• Dancougar: General Gildorome is perhaps the single most depraved character in the series. While Death Gaia and Helmut are insane, their way of thinking is extremely straightforward. Shapiro, however, preferred his knowledge of Earth geography and his battle tactics to take down the Cyber Beast Force. Instead of using conventional methods, Gildorome preferred psychological methods, such as using a Lotus-Eater Machine to hypnotize a whole town to kill them when they can't even fight back. In the end, his method caused the highest number of innocent victims in the most brutal way possible.
• Danganronpa Gaiden: Killer Killer: Ted Chikatilo, known as the "Million Killer" and owning the title of Ultimate Pyrotechnic, is a member of Ultimate Despair and an infamous bomber who's one of Future Foundation's most wanted criminals. Chikatilo has a fascination with explosions and violence, using the Tragedy to his advantage to turn people into "beautiful fireworks". Responsible for a number of bombings and coming off his latest killing spree where he murdered a platoon of Future Foundation agents, turning one into one of his "art pieces", Chikatilo sets his sights on Killer Killer for bragging rights. Knowing Future Foundation was planning to lure him out, he tried to trick Takumi and Juzo, disguised as him, into fighting each other before coming out and attacking the two. When Takumi managed to thwart his attempt, Chikatilo became more aggressive, killing countless people around him, before trying to blow up Takumi, his partner Misaki, and anyone around in a wide range explosion. A narcissist of carnage, with thousands of deaths to his name, Ted Chikatilo is one of the worst criminals in the world of Danganronpa.
• Darker than Black:
  • Season 1—The Black Contractor:
    • Director Yoshimitsu Horai and Eric Nishijima are secretly high-ranking members of the sinister Syndicate. Overseeing the coverup missions assigned to their assassination teams, the Director and Nishijima regularly order witnesses to Contractor activity silenced, and have their own followers killed the moment they risk exposure for the organization. Constructing the Saturn Ring to destroy Heaven's Gate—which empowers the Contractors—the two then lure a Contractor terrorist group to Tokyo to stir up chaos and justify their genocide as being for the good of humanity, and when their plan is foiled, the Director murders Nishijima to cover up the incident and escape consequences.
    • Decade, a high-ranking member of the Syndicate, is a ruthless supervisor in MI6 who utilizes Contractor squads as assassins and operatives ostensibly to benefit Britain but in truth has many murdered simply for the ends of the Syndicate. After having numerous people eliminated by his forces, Decade is revealed to be targeting all the Contractors by helping to initiate the Saturn Ring project, stating he planned to keep November 11 in the dark until the final moment when Contractors were completely exterminated.
  • Season 2—Gemini of the Meteor:
    • Genma Shizume is a disarmingly laid-back Contractor working for Section 3 who is in reality a brutal sociopath. Sent to chase after the young Suou Pavlichenko, Genma insinuates his want to sexually assault her, and when a group of Russian soldiers prove problematic to his mission of capturing her, he sets up a massacre at a public train station to deal with them. Secretly a mole for the CIA, Genma brutally rapes and tortures one of his Section 3 teammates to death while extracting her memories and later mocks the woman's lover when he encounters her.
    • "The Doll Sings to the Wind Flower...": Ilya Sokoloff is a Contractor working for the FSB with a history of being a serial killing sadist behind him. Having slaughtered numerous women, including the niece of his own boss Repnin, Ilya eventually grew out of these tendencies as a Contractor having decided it was best to murder his victims by asphyxiating their brains to make their deaths "relaxing". Killing many more people, Ilya attempts to abducts Suou Pavlichenko and July while murdering others as he desires.
  • Gaiden OVA: Claude, real name Shichi/Xi-Qi, is the Big Bad who stands out from the normally amoral superpowered Contractors by his outright hatred of normal humans. Claude torments his enemies before killing them by using his powers to masquerade as one of their loved ones and seeks to turn Yin into the Person of Mass Destruction Izanami. Claude is even callous enough to turn her into Izanami when she is in a base of Contractors, knowing that this would mean that her powers would kill everyone on the base, showing he cares nothing for his own kind even while trying to make a world where they rule over regular humans.
  • Flower of Darkness manga, by Tensai Okamura:
    • Harvest serves as an Evil Counterpart to Hei, replacing Hei's respect for humanity with contempt, considering them to be weak and pathetic. Harvest possesses the titular "Flower of Darkness" which can be given to a person to grant them powers, but sadistically forces the recipient to kill their best friend in return for power, also giving the best friend a Flower to entertain himself with the struggle. To prove his superiority to Hei, Harvest distributes Flowers to all of humanity in an effort to prove to himself that there is no such thing as morality, then pettily trying to destroy the whole planet when his plans are foiled.
    • The girls' academy volleyball coach, Daisuke Mioka, is a handsome, charming man who takes advantage of his young students by seducing them and secretly making videos of the sex to sell on the internet. When one student finds out, Daisuke tries to win back her trust by having a group of his friends rape her, before sweeping in to act as the hero who saves her. Daisuke also promises his friends that he will be "a little late" so that they can begin violating her before he arrives.
• The Dark Myth by Daijiro Morohoshi—The Legend of Jofuku epilogue chapter prequel: Lord Jofuku is a sorcerer in the court of Qin Shi Huangdi, who participated in the purge of Confucian scholars, who Jofuku had Buried Alive by the hundreds, with the father of protagonist Gansei among the victims. When the Emperor orders Jofuku to find the Elixir of Immortality, Jofuku gathers hundreds of teenagers from different regions of China and sails to Japan to search for the source of a mysterious clay idol. When the people of Wa guide Jofuku to a tribe that realizes his hostility, Jofuku summons clay golems to exterminate the entire tribe, sparing a single tribesman after he leads Jofuku to a mysterious mountain. When Seiei defies him, Jofuku has him whipped before confessing his real goal to use his captives in a ritual to become one with the God Konton and keep "immortality" for himself.
• DARLING in the FRANXX: Papa and the Vice Chairman are the face of the VIRM, a vicious alien species that assimilates others and exterminates those which refuse their subjugation. Arriving on Earth, the VIRM exhaust the planet's magma supply, leaving humans as a target for the Klaxosaurs and rule the planet as a cruel regime, with those who defy them having their minds wiped or being left in cryo-storage for their disobedience. After a devastating assault, the VIRM attempt to completely wipe out the Klaxo-Sapiens. When Papa reveals himself as the VIRM, he tries to absorb the souls of all humanity before deciding to simply destroy Earth, tormenting the heroes as they try to stop the alien monsters.
• Dawn Tsumetai Te: The seemingly affable, mysterious Doctor is the actual creator of the Nightshift virus. Having created it accidentally, the Doctor tried to sell it for profit, accidentally infecting protagonist Takeshi Nagasawa and liberating the virus. Allowing the virus to spread due to scientific curiosity, the Doctor saves Nagasawa's life in order to blackmail him into helping him to hunt other infectees. After the infectees start to develop conciousness, the Doctor blackmails Akemi, another Nightshift infected, into helping him to capture the rational ones in order to create a drug that destroy their conciousness by promising to save her best friend. When Akemi betrays him, the Doctor reveals that he killed said best friend, asking her if she wants to see her body parts before killing her after she attacks him. Despite his charismatic behavior, the Doctor is a selfish scientist willing to betray everyone in order to benefit himself, with every positive act of him being motivated only for his own interest.
• "Day of the Whirlwind", by Hisa Masato, from Four Billion Nights: Katagiri Kenta is the Kamaitachi Killer, taking inspiration from the Yōkai Kamaitachi and beheading his victims. Having already killed four women, Kenta keeps their heads in his apartment. When the investigators reach his house, Kenta is haunted by the ghosts of his victims, making him run away and prove his culpability to the heroes. Then, Kenta brags about his murders and attacks the investigators to add their heads to his collection, smiling when he realizes that the Yōkai Nezuchi is vulnerable to his metal knife.
• Deadman Wonderland is a Hellhole Prison, thanks in no small part to the psychopathic assistant warden; the Big Bad; and a Mad Doctor:
  • Tsunenaga Tamaki, formerly a reclusive and indifferent otaku, becomes a tyrant who cares for absolutely nothing but himself and his games. When the Great Tokyo Earthquake occurs, he leaves his mother to die so he could find a backup generator. He is also responsible for designing the prison and forcing prisoners to participate in Death Games by poisoning them upon arrival and only awarding antidotes to their winners. As a sadist who sees defeating the Wretched Egg as a game, he also creates the Forgeries, prisoners who are turned into artificial Deadmen and brainwashed into obeying Tamaki's orders.
  • Rinichiro Hagire, the prison's real director, is a sadistic sociopath who will do anything for his research. Using Shiro as a guinea pig for research on how to improve a person's immune system, Hagire becomes obsessed over his subject's ability to regenerate. From crucifixion to vivisection, Hagire grows fond of conducting brutal experiments on her and becomes directly responsible for her becoming the Wretched Egg. He also manipulates Chan and En to use their Branch of Sin to invade and override other people's bodies and personalities when he's on the verge of death, and cannibalizes the remains of defeated Deadmen.
  • Rei Takashima is a sadistic surgeon employed by Deadman Wonderland. Happily removing the body parts of any Deadman who loses their fights, Rei is enraged when unable to harm one young girl. Rei also creates countless artificial Deadmen sapped of free will, and when hero Ganta gets in her way, tortures him to her own arousal.
• Death Note: Light Yagami is a brilliant, egotistical student who finds the titular Death Note and soon embarks on a quest to become the God of a "perfect" world he will create. After killing multiple criminals with the Note, Light flies into a rage when a man denounces his public name of "Kira" on TV, gleefully murdering the man on the spot. Once FBI agents investigate, Light tricks one of them into killing the others, revealing himself to one agent to gloat and later forcing the man's fiancée into suicide, cruelly taunting her while doing so. Later, to eliminate his chief pursuer and rival L Lawliet, Light pulls a Memory Gambit where he has the Death Note given to a man he knows will misuse it and pulls off a scheme that kills multiple people, including L. After L's death, Light reduces the global crime rate through sheer volume of murders, with a body count stated to be worse than any genocide. Not even lovers or family members are immune, as Light uses one of his two girlfriends as bait for another rival and forces her to burn herself to death, also eliminating any evidence along with her and contemplates murdering his own sister the moment she becomes a liability. When exposed, Light attempts to justify himself as well-intentioned, but is revealed as "nothing more than a crazy Serial Killer''.
• Deathtopia, by Yoshinobu Yamada: While Kou Fujimura learned that while all the Cheaters harbor dark thoughts, many of them live normal lives. However, the following trio embraces their dark side:
  • Magata Agito, Kou Fujimura's biological uncle, awakened a combination of genes that turned him into the first Cheater. Arrested for having murdered two women after returning to Japan, he was experimented on by his brother-in-law to understand the nature of his virtual immortality. Saved by his own sister despite him having abandoned her, Agito tries to take her body, accidentally awakening her own powers, damning her to have her body being constantly destroyed and reformed, leading to his brother-in-law becoming the Cheater Ud. Naming himself The Master, he manipulates younger Cheaters to become his followers before sending them to kill Ud and steal the deformed remains of his sister to use them for his plan to launch a coup against the Japanese government alongside the military, intending to kill half of the population of Tokyo. When Kou confronts him, the Master leaves him to die in the fire alongside his girlfriend. A man that enjoys hurting his own family, the Master planned to kill millions to create a twisted utopia where Cheaters are free to hurt and kill as many they want.
  • Karen Kirishima is the first major villain and one of the most sadistic. A beautiful assassin who manipulates men into joining her gang, Karen takes the eyes of her favorite victims to keep them in jars. Intending to take Kou Fujimura's special eyes, Karen sends her gang to hunt him. When a man that loved her has doubts and crashes her gang's car, injuring many of her followers, Karen beats him to death and takes his eyes, convinced that "low-level" men like him should be glad for it. A sadistic killer feared even by other Cheaters and a terrible leader, Karen brutally murders her own gang, leaving their scattered bodies as part of a horrific yet useless trap.
  • Mitsuo Okita, aka Reverse , kills people who appeared in magazines by using his power to emit pheromones that prevent his victim from moving before slowly "reversing" their organs, leaving them to die from blood loss and exposed organs. Aware that his power is useless in combat and at long distances, Reverse waits years between his killing sprees, having killed 28 persons, including the family of Yui Kisaragi, who survived due to not being in the house during Reverse's assault. Returning to his old habits, Reverse kills a couple before being lured into Yui's trap. Managing to use his powers, Reverse paralyzes Yui and tells her the details of her family's death before trying to "reverse" her organs.
• Defense Devil: Elimona is a manipulative, sociopathic Fallen Angel who believes everything exists for her amusement and pleasure. Stripped of her divine position for manipulating humans into warring against one another, Elimona conspired to gain her powers back by manipulating the good-hearted demon Kucabara into being her errand boy. When she reveals her true plans, Elimona poisons Kucabara's friend Idamaria and steals the latent powers of Lilith from her. She sets up the demon world—where demons aren't actually evil—to be subject to genocide at the hands of the angels, while she regains her powers. When she sees Kucabara's brother, Legato, planning to destroy the demon world before the Angels can arrive, she threatens to enslave their souls and submit them to a world of slavery at her and the other angels' feet. Elimona displays a Lack of Empathy for everyone, even her own angel kin, and when defeated, she opts to drag as many of Kucabara and his friends into the grave with her as she can.
• Deltora Quest: The Shadow Lord is an envious, ancient ruler of the Shadowlands who invaded Deltora in the past. Driven off by King Adin and the power of the Belt of Deltora, the Shadow Lord has spent centuries isolating the royal family from their people and spreading suffering across Deltora in preparation for another invasion. Invading at last, the Shadow Lord has most of the Palace's inhabitants slaughtered and the Belt destroyed, hiding the Seven Gems at the most dangerous places in Deltora, including the Valley of the Lost, which the Shadow Lord enchanted to turn everybody who comes to it into lost spirits. The Shadow Lord's armies spread across the land, exterminating the entire Jalis tribe save for Glock and capturing countless people for gladiator fights in the Shadowlands. When the Gems are reunited on the reforged Belt, the Shadow Lord has Dain pretend to be an heir and uses him to lure heroes into the Royal Palace. The Shadow Lord comes personally to end the rebellion, planning to slaughter the heroes and all their allies.
• Demon City Shinjuku: Levih Rah made a pact with the powers of darkness for power due to envy over his fellow pupil Genichiro being superior to him. Promised power in return for granting the demons dominion over Earth, Levih Rah defeats Genichiro but is prevented from summoning the demons further than Shinjuku. Men are killed, women raped and children go missing as Shinjuku becomes a twisted hellhole where demons prowl and Levih Rah himself reigns. When Genichiro's son arrives to stop Levih Rah, the sorcerer tries to have the world's president assassinated and use his daughter as a ritual sacrifice so he can complete his work and give demons dominion over all the world.
• The Demonic Beast Front franchise:
  • Majuu Sensen, by Ken Ishikawa: Professor Genzō Kuruma, the father of hero Shin'ichi, is one of the 13 Apostles serving God. He seeks to create a new breed of human/animal hybrids called "New-Men" by morphing people's cells, hoping to accomplish everything before God starts his apocalyptic recreation process. Having experimented on Judas's sons and turning them into dust creatures, he starts the story by massacring everyone in the International Science Institute, before using Shin'ichi as a guinea pig for his painful New-Men experiments. Considering Shin'ichi a failure, he decides to experiment on his wife instead, taunting Shin'ichi about her results. Deciding to cast aside his own humanity, Kuruma has Shin'ichi slowly electrocuted to death, then leaves him and his wife to die in a house fire. Continuing to perform New-Men experiments on random people with his fellow scientists for five years, he tries to kill Shin'ichi after hearing he's still alive, and later orders Professor Shaft to flood the Earth in an attempt to recreate Noah's Ark.
  • Beast Fighter: The Apocalypse anime:
    • Having survived God's apocalyptic recreation process, Dr. Genzō Kuruma plans to resurrect God and use him to create a new world with him as its ruler. Continuing to plot the death of Shin'ichi, Kuruma sends New-Men out to take him down, uncaring of the innocent casualties. Creating an army of non-binary clones to populate his new world once he floods it, Kuruma locks one of them, Noah, up for being rebellious, calling them a failed experiment. Murdering Ayaka by draining her of her magical blood, Kuruma summons Mars A and Mars B to try and get them to kickstart another apocalypse so that he'll become the new world's God.
    • Episodes 4-7: Chancellor Semimaru is the leader of a small country hoping to become the new God and obtain his powers. Making Dr. Rockry inject the blood of Shin'ichi into him, Semimaru has him locked up to be used as his pet scientist. Seeking the death of Shin'ichi, Semimaru sends his men out to destroy a train full of people and attack a small village. After failing to kill Shin'ichi in Honekami, he orders the destruction of the entire town for bearing witness to the event, uncaring of the millions of lives lost. Torturing and fatally wounding Rockry for information on Shin'ichi, Semimaru dies proclaiming himself the world's only God.
• Demon Lord Dante 2002 anime adaptation:
  • God himself is the Big Bad of the series. An ancient energy being who first arrived at the cities of Sodom and Gomorrah, God committed genocide and torture upon the inhabitants when they refused to worship him, before attempting to torture the survivors for eternity. Upon the demons and devils rebelling against him in present day, God engineers a series of horrible disasters and attacks before draining his energy from all the humans he had created, driving them insane and leading to bloody massacres over all of the world with the knowledge God has done this on many, many worlds before arriving on Earth. Sadistic and egotistical, God believes he deserves worship and will enact nothing short of terrible vengeance for any minor slight.
  • Lamia, one of the treacherous devils known as the Four Devil Kings—and possibly the worst of them—leads her forces to a series of brutal attacks that kill many civilians after she is released by God to stop Dante. Not satisfied with this, Lamia begins abducting young men and women, impregnating the women with her demonic spawn and using the lifeforce of the men to feed her progeny. Lamia's common MO is to have her children eat their way from the "mothers" and use them to overrun entire countries, devouring everyone therein. When the devil Medusa interrupts, Lamia attempts to use her as a host as well before trying to devour Dante himself.
• Demon Slayer: Kimetsu no Yaiba: Throughout this dark world, the following demonstrate the monstrosity of demonkind:
  • Muzan Kibutsuji was born a sickly child in the Ubuyashiki family, but through a doctor's attempts to cure him incidentally became the first and mightiest demon and grew obsessed with his own perfection. Corrupting others into demons by preying on their weakness at their lowest then infecting them using the special properties of his blood, Muzan develops the system where demons feed on humans en masse for power, leading to countless innocent deaths as he maintains this system for over one thousand years, with his blood poisoning and painfully killing any who so much as utter his name in front of his enemies. Muzan is also personally responsible for killing the mother and siblings of the young hero Tanjiro Kamado, as well as the demonic transformation of his younger sister Nezuko. When encountered, Muzan escapes notice by turning an innocent man into a demon and siccing him on his wife before killing several other humans in a fit of pique when they trouble him. Muzan orders countless humans slaughtered, and when several of his top subordinates, the Lower Ranks, disappoint him, Muzan massacres the survivors, deciding they are too weak to survive. Later attempting to massacre all of the Demon Slayers, when Muzan knows death is inevitable, he intends to turn Tanjiro into a demon to kill them in his stead. A sadistic, cowardly sociopath predicating a survivalist society of bloodshed to maintain his own safety, Muzan stands responsible for the most death and suffering in the series.
  • "Mugen Train" arc: Enmu is Lower Rank 1 and a suffering-addicted psychopath. As a human, Enmu claimed to be a doctor, falsely "curing" the dying for his own profit and prestige until being made into a demon by Muzan. Insanely worshipful of Muzan, Enmu swiftly kills to climb the ranks of the demons and even survives Muzan's purge of the Lower Ranks by impressing his master with his love of pain and death. Empowered and sent after Tanjiro, Enmu uses his powers over dream and sleep to put Tanjiro and his friends into pleasant dreams while tricking humans into entering their dreams to destroy their minds. Enmu promises to give train passengers kind dreams, but delights in twisting their dreams into horrific nightmares, and when cornered by Tanjiro opts to fuse with the train itself and try to devour all 200 passengers, gloating how he means to torment his victims before he eats them to further empower himself.
  • "Swordsmith Village" arc: Gyokko is Upper Rank 5 and an insane artist who creates new pieces with his victims. Upon being sent to the swordsmith village, Gyokko decides to kill everyone in the village after murdering several smiths and taking others to fuse them into a macabre, living sculpture that he tortures by sticking swords through them, gleefully describing how he plans to replicate it on a grander scale with the village innocents. A complete narcissist, when Gyokko finds a smith more dedicated to his work than to noticing him, Gyokko opts to begin torturing him to try to break his concentration.
  • "Sunrise Countdown" arc's Chapter 188 ("Sorrowful Love"): The unnamed snake demon in Obanai Iguro's past was a low-level demon with a hunger for children. Bargaining with Obanai's family, the demon would murder people to allow the all-female bandits to live off the stolen wealth in return for them providing the demon with newborn babies on a steady stream to consume. Upon Obanai's birth, the demon had him raised and prepared as a meal, as he was the only boy and had alluringly unusual eyes. Having Obanai's face mutilated to resemble her more, the demon massacred all but one of Obanai's family upon his escape before closing in on him to eat him as well.
• Denpa Teki na Kanojo anime: Kiyoshi Kakura is a Serial Killer who has brutally beaten at least 13 people to death. Once a normal boy, Kiyoshi one day suddenly snapped and raped his neighbor and sister figure Sakuya, her mind breaking due to the horrible incident. After snapping once again later on and killing an innocent high school girl and bragging about it, he and Sakuya, who became obsessed with these deaths, began their killing spree during rainy nights, including the main character Juu's friend Fujishima. After being lured out by Sakuya through an anonymous text, Juu encounters Kiyoshi after his latest kill, where he claims his victims were all aliens and it's his duty to kill them all as a covert agent. After trying and failing to kill Juu, Kiyoshi was arrested for the killings and then killed himself while in prison.
• Descendants of Darkness: Dr. Kazutaka Muraki, while handsome and charming, has, as of the start of the series, already spent several years systematically kidnapping, dismembering, and vivisecting small children, raping adolescents and infecting them with slow, agonizing fatal diseases, and seemingly murdering every grown woman he comes across, whether to use them in scientific experiments to attract the attention of the Shinigami or just for fun. Muraki also specialized in Mind Rape, whether it's mentally torturing a girl madly in love with him into developing split personalities, mind-controlling suicidally depressed pop stars into becoming blood-drinking monsters, or stalking and harassing one of the Shinigami with so much misdirected guilt that he finally manages to drive him into a catatonic state, in which state he fully intended to vivisect the guy and use his powers to bring Muraki’s older (half-)brother Saki back to life, just so that he could kill him more slowly and painfully.
• Detective School Q: Horie Takayuki is the primary murder victim of the Psychic Murder arc, but it is quickly revealed that Horie was more than deserving of the death blow he was dealt. Years ago the abusive chief of staff of the National Talent Development Center who seemingly created the project just to get government money, Horie would take in young children and put them through experiments to test their capacity for psychic abilities, horribly beating them if they fell short of expectations. In truth using the Center just to have children at his disposal for him to molest and act out his depraved urges on, Horie eventually murdered one of the children in his care and killed his partner to keep the death silent. Horie gets away with his crimes for years, hurting countless children and taking smug satisfaction in his acts.
• Devil Devil, by Yūki Miyoshi: The Shadow of Satan was originally a demon soul without a body surviving inside his brother Satan. Hating the world, when Satan fought against God, the Shadow took the opportunity to corrupt both of them, take control of their bodies and divide the soul of his brother into multiple fragments. After the demon Sword fought some fragments, the Shadow ordered his best friend to kill him and when said friend avoids it, the Shadow tries to kill him too. Sending some demons to find the fragments in the human world, the Shadow convinces one of them to absorb his companions before discovering that he planned to absorb all of them. Willingly butchering Satan's resurrection/empowerment to ensure his death, the Shadow takes control of Heaven as God, creating monstrous angel/demon hybrids, turning Heaven into a horrific dimension, and launching an invasion to Hell with the intention to destroy it alongside the human world and heaven itself.
• Devil May Cry: The Animated Series:
  • Sid is a cowardly lesser demon who will do anything, including murdering children and fellow demons, to rise in the ranks of Hell. Killing a man, Sid wears his skin to manipulate his friend, Nina Lowell, and later threatens Nina's life to force her daughter, Patty, to activate his ritual to summon the great demon Abigail, to absorb his power. Summoning a demon army to slaughter everyone on Earth, Sid cares nothing for the death and destruction as long as he gets to rule Hell, just to eradicate his own inferiority complex.
  • "Not Love": Mayor Mike Hagel's butler is a seemingly well-mannered servant whose true loyalty lies with the demon Belphegor, wishing to sacrifice the entire human population by condemning them to be Eaten Alive. Working alongside the good-hearted demon Bradley in making the preparations for their master's arrival, the butler stabs the mayor and uses his body in a ritual to summon Belphegor for him to devour the entire city while claiming that they would eventually destroy the human world. A human who stood in contrast to his benevolent and demonic partner-in-crime, almost driving his own race into extinction to satisfy his master, he served as an example of how some humans are even worse than demons.
• Diabolo: Nebiros is known as the most cruel and twisted of Diabolo's generals. The leader of the Six Great Spirits of darkness, Nebiros has no compunction sacrificing them to meet his goals. When he manifests on Earth, he happily tortures a church full of his own worshipers to death with a Slasher Smile on his face. When his survival while inhabiting the hero Rai is threatened, Nebiros tries to break free and possess Rai's friend Ren, to erase Ren and inhabit his body as a shell.
• Dogs: Bullets & Carnage: Angelika Einstürzen specialized in human experimentation, starting on her test subjects when they're young children. Chronologically, the first thing we see her do is tell Heine, a member of one test group, that if he took part in an extremely dangerous experiment, he'd save all of his friends from the same fate. Once it was clear that the experiment was a success, she no longer needed the rest of the test group and had them go berserk and murder each other, while she forced Heine to watch. Next, she sends a large number of her old test subjects to invade the Underground City and slaughter as many people as they could before she blew her soldiers up. She didn't even do this because she had something against the people she had killed. She just wanted to get rid of her old, defective test subjects, while also getting the attention of the mayor, who resided on the surface. She figured the easiest way to kill two birds with one stone was to blow her men up and take hundreds, if not thousands of innocent civilians with them. Afterwards, she sends one of her many bodies to one of the districts hit hardest by her attack and tells the people there that their friends and family, who had been kidnapped long ago, were among the attackers that the people had killed, just to see how horrified they would be. She also shocked one of a pair of young twin sisters who understandably didn't want to go back to her for more brainwashing and Mind Rape. She does all all of this either for scientific research or just for fun.
• Dog Soldier: Owing a great debt to American action films, especially those of The '80s, this manga has some very nasty villains:
  • "Zardoz" & "Big Shot": Zardoz, founder and leader of the New Revolutionary Army, is a vicious terrorist responsible for countless attacks, including one that claimed the lives of the parents of John Kyosuke Hiba. In present, Zardoz's men bomb a jumbo jet that is filled with passengers, planning to use the distraction to kill President Ronald Reagan. When this fails, Zardoz has them hijack another plane to fly it, with all passengers, into Reagan's meeting place. When he learns Reagan is in Tokyo, Zardoz and his forces attack an airbase and slaughter all the soldiers before taking the President hostage, planning on seizing control of a nearby nuclear arsenal with no compunction in burning Tokyo to ash.
  • "A Lonely War": Muammar Gaddafi himself, the dictator of Libya, is secretly working with Dr. Göppel, a nuclear scientist who wants to get back at the US for cancelling his research on nuclear weapons. When the two cause a plane, which Göppel is on, to make an emergency landing in Libya, Gaddafi takes the crew hostage. When Hiba and his friend Fudo go on a rescue operation, Gaddafi has all three hundred passengers massacred, including a father in front of his young son and tortures Hiba by carving a grid into his back and ripping off chunks of his skin. Having worked with Dr. Göppel to design an ICBM hundreds of times stronger than the nuke, and Göppel having set off the weapon with his dying breath, Gaddafi plans to nuke the entire West. When he and Hiba engage in a duel to the death, Gaddafi boasts of consuming the entire West in nuclear fire, not caring that he'll sentence his own people to death by retaliation in the process, as he can simply hide out from the retaliatory strikes in his nuclear bunker.
• Dokuhime:
  • Queen Datura Metel Mitragyna is the selfish, hedonistic ruler of Mitragyna. To mock the lowborn king of Glandol, Icarus, at a feast, the Queen poisoned common folk dressed as nobles at his table. Icarus allows the neighboring nations free access to Glandol's vast water supply, on the condition they cease hostile action, including banning Mitragyna from exporting poison, enraging the Queen. Using assassins known as "poison princesses" to create political instability, the Queen tries to have the Glandol king assassinated and when this fails, poisons the water of another country, framing Glandol to start a war.
  • Mandrake raises the poison princesses by having them ingest food and drink laced with poison, even violating them with a poison-coated stick, until all of their bodily fluids will kill any they touch. Using the girls as assassins, Mandrake cares nothing for them and has those who fail their missions or run away hunted down and burned at the stake. When the Queen orders a nation's water supply poisoned, Mandrake has a young poison princess decapitated and her body thrown into the stream to infect it with her blood.
• Dokuro:
  • Aiichiro Kanehira is the repulsive, greedy founder and leader of the Nirvana Church of Creation, a Corrupt Church which exists solely for his benefit; Kanehira doesn't even believe in the tenants of the Church. His followers go into debt to give money to the Church, some even committing suicide; Kanehira doesn't care. While not killing anybody himself, Kanehira has his Church Police kill at least dozens, possibly hundreds of not more of enemies. He also has an orphanage where children are abused, raped, and generally treated horribly. He also allows, if not orders, horrendous medical experiments, and organ trafficking, including some of the children. Finally, Kanehira takes advantage of his followers; in one instance, he took sexual advantage of the mother of hero Kikuchi Takeo, then just cast her aside like a piece of garbage. This resulted in her killing herself and trying to kill Takeo as well; this in turn motivated Takeo, a former elite member of the security unit, to take down the Church. While Kanehira at various points seems to care about his followers or his daughter, at the end, Kanehira Aiichiro is shown to care about nobody but himself.
  • Kawashima Junta is the chief prison guard of the sanatorium where Takeo is sent after killing a corrupt police officer. Previously, he was in charge of Kanehira's orphanage, where he beat and abused the children, including them making them drink from bowls like dogs. He also raped-—possibly more than once-—Takeo's friend Mudo. In the sanatorium, Kawashima hosts the Rumble Fish, where he would pit prisoners against each other; the fight could only be stopped by Kawashima, who loved seeing them kill each other. When a prisoner calls Kawashima a "maniac", Kawashima responds by shoving a pencil through said prisoner's mouth and nose. Finally, Kawashima took part in the organ trafficking, both at the orphanage and at the sanatorium.
  • Professor Koganei works at the sanatorium, and is responsible for the organ trafficking and medical experiments. He works with medical companies, and uses the prisoners as guinea pigs for testing new drugs. He doesn't even believe in God, but is a member of the Nirvana Church of Creation, as they allow him to conduct any type of experiment, legal or not. He considers taking the prisoners' organs "recycling of trash". He had the sanatorium's actual warden locked up and drugged for a few years. Finally, there are the "zombies", humanoid abominations trapped in an And I Must Scream state.
• Dokuzakura, by MITA & Yamii Yamamoto: Yukiya Honjou is a talented TV actor who hides his horrible personality behind a beautiful face. Using his power, Yukiya manages to have sex with many women, but abuses them, even having them tortured if they don't satisfy him. Taking advantage of the theft of 300 million yen from Sakura, Yukiya murders a banker who had been impregnated by him, also murdering her unborn child. With the help of a detective, Yukiya eliminates all those he considers a threat, or who are no longer useful to him, including the producer who protected him, his torturer, and a policeman. Yukiya also wished he could abuse Atsushi's three girlfriends when he managed to get the drop on him, one of them being a minor. Ruthless, sadistic, and cowardly, Yukiya will do everything possible to protect his utopia of degeneration.
• Dolls Fall: Headmistress Chloe Zola-Kanno fell in love with killing the helpless when she witnessed her own orphanage headmistress go mad and kill her friend and began killing orphans with her. Seeking to resurrect an evil witch by torturing and killing virgins, Chloe spends a century bringing girls with special powers to her orphanage by killing their families and bathing in their blood to stay eternally young. Renting the girls to the townsfolk to use for sex rituals, when a pair of reporters upload Chloe's crimes to the internet, she goes ballistic, ordering all the orphans killed, before having her staff commit suicide to appease the witch's bloodlust.
• Domu: Old Cho, real name Chojiro Uchida, is an elderly man with Psychic Powers and the mind of a sadistic child. Routinely driving the residents of his apartment complex to suicide—with over 30 victims in under 3 years—to steal their belongings and keep them in a room, Old Cho reacts to investigators brought in to investigate the mysterious deaths by mentally torturing one of the lead investigators and forcing him to jump to his death. Barely stopped from making a baby crawl off a balcony by young psychic girl Etsuko, Cho retaliates by possessing a man and trying to make him try to stab Etsuko to death and then forcing the man to cut his own throat in front of Etsuko, traumatizing her. Cho later possesses Yoshikawa, another tenant, in another attempt to kill Etsuko, scoring a number of other murders through him—including two of children, the latter of Yoshikawa's own son—and then rigs a series of gas leaks around the complex, causing a series of explosions that cost dozens of lives. Maintaining a childish glee when committing his atrocities while simultaneously demonstrating he knows full well what he's doing is utterly wrong, Cho is petty, selfish, and views people as nothing more than toys for his own amusement.
• Dragon's Dogma's "Gluttony": The Mayor is a gluttonous pig of a man who has a Cyclops eat children under false pretenses that they are ritual sacrifices; he would only spare those who hand over all their food to him, while letting them starve to death. When Ethan and Hannah battles the Cyclops, the Mayor has his men attack the duo, potentially putting them in danger of facing the Cyclops's warpath.
• Drakengard 3 prequel manga:
  • Fatal Crimson (aka The Red Unto Death):
    • Nero, one of the last elves alive, is a swaggering sadist and the traveling companion of the male One. Together the two have been slaughtering their way through entire towns and kingdoms in an effort to extinguish the otherwise-incurable Red Eye virus. Unlike his partner, Nero only cares about indulging himself, having fun, and murdering as many people as possible—infected or not—while constantly imploring the male One to become even worse. When Nero and the male One ingratiate themselves to a kingdom by saving its princess, Nero attempts to rape her, and is only forced to substitute her with the princess's handmaiden by the male One's intervention. Not even the revelation that his own sister is an Omnicidal Maniac dampens the grin on Nero's face; Nero always wanted to destroy the world with his own hands, and when his sister is dead, Nero hacks off his partner's still-living head to keep with him as he moves on to keep spreading the virus and eventually tear apart the world.
    • Nero's sister, the imposter posing as the female One, is no better than her brother. Likewise a sadist who tricks the male One into thinking she's his sister before stabbing him for a sick chuckle, the imposter murdered her clan elder to take his magical power and then used that power to amass a huge following of people infected by the Red Eye. The healing magic Nero's sister uses is illusory—all of her followers are secretly kept in their physically ravaged states and turned into brainwashed soldiers Nero uses to commit political assassinations and spread the virus even further. Nero is responsible for manipulating war and bloodshed on catastrophic levels, all for the purpose of seeing humanity rend itself apart.
  • Five Intoners: Bass, Lord of the Country of Sands, is a truly vile piece of work even among his fellow Lords. Bass has kidnapped dozens of children during his reign, murdering their parents and anyone else who tries to appeal to him, hanging the bodies of his dead citizens on his castle's walls. Bass murders all the children he's captured in order to make sick artwork out of their dead bodies, making dolls made of skin and bone and stuffing the corpses of the kids he's murdered in order to mount them. Bass also turns people into horrific, misshapen monsters he looses on anyone who tries to stop him.
• Dream Dimension Hunter Fandora: Yog Sothoth/Yogu Sotho Sogos is a dimension-traveling criminal who desires absolute godhood. Once a nice young man living on Deadlander, his life began to change after the destruction of his planet and the death of his girlfriend Fontaine. Consumed by despair and hatred, he later finds the Endora jewel, gaining powers after the jewel absorbed the evil in his heart. Becoming drunk on his new powers, he proceeded to conquer the planet Aura, killing Fandora's royal parents in the process. Taking over the Kingdom of Lam, he slaughters the king and queen, brainwashing their daughter Leimia to serve him. Posing as Pope Gilsburg, he rules the kingdom with an iron fist. Seizing Fandora's Lupia jewel, he forces her to fight over a pit of spikes for his own amusement, killing Leimia after she frees herself from his control. Seemingly defeated, Yog resurrects himself and recreates Deadlander as a planet populated by dimensional criminals. Posing as the God of Blue Light and resurrecting Fontaine as his maiden, he creates a physical manifestation of his remaining conscience named Sotho, ordering him to bring the Lupia jewel in return for Fontaine, planning to combine with both him and the jewel to obtain more power. Once Sotho realizes who Yog is, Yog kills him and Fontaine, destroying Deadlander again. Becoming a starship captain, he sets out to conquer every dimension, having already conquered 1/3 of them. Coming close to achieving ultimate power, he tries to kill Fandora for her Lupia jewel.
• Dream Eater Merry anime: The seemingly-friendly guidance counselor Ryota Ijima and his Dream Demon "Mystleteinn" Treesea are vicious partners-in-crime who gratify their mutual sadism by implanting Dream Demons in the students Ijima counsels, whereupon Treesea butchers them and leaves the students as hollow, apathetic shells. Treesea previously establishes her nastiness through a vicious massacre, and Ijima glories in breaking the dreams of the students who trust him, even brutally beating one by kicking her head. In their battle, Treesea imprisons Merry in a bud of despair to drown her, mocking the subsequent failed Heroic Sacrifice as "worthless" as Ijima gleefully beats down the heroes himself.
• Dream Hunter Rem: Professor Shinigami, real name Dr. Shimura, was a sadistic Serial Killer of women in life who kept the bodies of his victims in suspended animation before being supposedly killed. Returning as an entity capable of murdering people through their dreams, Shimura returns to old habits by butchering countless more young women in their sleep and even trying to torture the young daughter of the cop who tried to gun him down to death in revenge. When Rem plunges into his victim's dreams to fight him, Shinigami eagerly attempts to kill her too through a swinging axe to slowly cut her open and bleed her out.
• Drifters: Aram is a knight of the Orte Empire, in charge of patrolling its lands where he would oppress the elves there, take their women to be made sex slaves, and kill any wandering Drifters. Burning the elven villages because two teenagers helped the Drifters, Aram personally kills the village elder, gloating that all non-humans will be exterminated, before ordering his men to kill some of the elves in the village, including the teenager, wanting to cut the elf population in half.
• Drifting Classroom: In this story taking place After the End, some people are driven to violence out of despair or survival, but two characters proved themselves to be evil for the sake of evil:
  • Kyusaku Sekiya was originally a friendly deliveryman who is revealed to have a penchant for harming children. After he is brought to the future, Sekiya threatens anyone who comes close to the kitchen, even burning alive the teachers who tried to reason with him. After a boy attempts to save a girl who was taken as a hostage, Sekiya fatally stabs him, and after killing the boy, Sekiya travels through several classroom while beating innocent students and stealing their lunches while demanding that they cry, informing them that he is perfectly fine with allowing them to simply starve to death. Seemingly defeated by the hero Sho Takamatsu, Sekiya threatens to stab a three-year-old if the students didn't obey him. Fighting against a giant centipede, Sekiya throws a boy at it and leaves him to be Eaten Alive. Traumatized by the experience which caused him to have a harmless child-like personality, Sekiya comes back to his senses after a boy pushes him down the stairs and forces him to swallow a strange mushroom, which ends up converting him and other children into spider-like mutants. Taking control of the school and turning it into a military-like dictatorship, Sekiya trains the boys to be his own Child Soldiers and sends them to their deaths when the mutants attack the school, while escaping with the food supply.
  • Scar Kid, the Arc Villain for Volume 5, is a budding psychopath and a fearmonger who leads a rebellion against Sho Takamatsu in the midst of a bubonic plague outbreak, igniting a war between the students. Starting his reign of terror by burning patient zero alive and trapping all of those who were close or merely affiliated with Sho inside a building, Scar Kid wants to burn them alive to reduce the school population by half, with his soldiers not above executing their own. Realizing that he himself is infected, Scar Kid touches Sho to spread the plague further, declaring that if he is infected, then everyone should also die a slow and painful death. Even after discovering his infection, Scar Kid still burns the building and orders his boys to throw spears and rocks at the windows to stop the students from escaping alive. Not warning his army about his infection on purpose, they also die from the plague before Scar Kid himself succumbs to The Black Death.
• Drifting Net Cafe, by Shūzō Oshimi: Terasawa is a formerly popular high school student who ruined his own life. Transported to another world, Terasawa stops the men trying to rape Miku only to rape her himself, before trying to force protagonist Toki and his high school crush Kaho to have sex. Returning to the Net Cafe after threatening the expedition to not reveal the truth, Terasawa uses a traumatized Miku with Stockholm Syndrome and blackmails the murderer Matsuda to frame Toki for murder and rape. When the survivors realize the actual guilty party is Matsuda, Terasawa betrays him and serves as the sadistic warden of Matsuda's improvised prison. Sexually taking advantage of Miku's trauma, Terasawa also prostitutes her to other males to earn their loyalty. When Terasawa's actions leads to a confrontation with the other survivors, Terasawa murders a man trying to rescue Miku and burns his corpse in his "campfire". After that, Terasawa mutilates the people left in the Net Cafe to turn it into his degenerate kingdom where the people praise his name, to revive his best days before starting a massacre after realizing that he was feared but not loved.
• Dr. STONE: Minister Ibara is the true ruler of the Petrification Kingdom. Having petrified the true leader with the weapon "Medusa", Ibara tried to kill said leader's baby son to remove any "witnesses". Reigning as a tyrant, Ibara has women abducted for the leader's harem, with the rule he is allowed to "sample" them first, gloating how he loves them to put up a struggle first. When Senku and the heroes of the Kingdom of Science alive, Ibara tries to petrify them forever, even sacrificing one of his followers to that end. A lecherous, fiendish tyrant, Ibara cares only to satisfy his own lusts for women or control.

E - F

• EDENS ZERO:
  • 'Guilst' (aka 'Planet Guilst Assault') arc: Illega is a bloated frog alien who pays criminals to kidnap and bring him women, who he turns into stone statues to be used as furniture. Once Rebecca uncovers his room containing hundreds of stone women, Illega arrives holding Copa at gunpoint, promising to release her should Rebecca kneel before him and become his toy forever. When news of the planet destroying Chronophage arrives, Illega plans to start his collection again on another planet.
  • 'Digitalis' (aka 'Hermit') arc: Spider goes by the name Jamilov in the Digitalis RPG Rogue Fantasia. Cheating to give himself an advantage, Jamilov wanders through the fantasy computer world, slaughtering the living NPCs for fun, while taking a special joy in murdering player characters so he can also kill them in the real world, exterminating entire towns. When he arrives at the town Shiki and Rebecca are at, Jamilov tortures and impales several PCs upon a spike to let them die slow and gleefully brings an army to massacre every living thing there, even trying to murder a child for an advantage. When thwarted, he tries to erase the Eden's Zero and kill everyone aboard the ship for sheer spite.
  • "Digitalis" & "Foresta" arcs: Dr. Müller is a figure from Hermit's past who manipulated her into activating the "Accelerator" under the pretense on saving Hook, a neighboring planet populated with androids. With the Accelerator being used to instead destroy Hook out of a sense of human superiority, Müller reveals his true colors to Hermit as he tortures and dismantles her for research and amusement. Making an escape from prison that resulted in the loss of his body, Müller crafted an O-Tech body for himself, using several humans as guinea pigs for his robotic experiments. Developing a grudge against the Rutherford family for withdrawing their funding from him, Müller kidnapped the young Kleene and Jinn after murdering their parents, and sadistically forced Kleene to watch as he dismantled her brother to be given O-Tech implants. Later partnering with Ziggy in his plan to take down Foresta with a robot virus, Müller is given an unlimited supply of humans to experiment on as he guards the server containing the virus. Once Hermit and Weisz arrive to stop him, Müller tries to have all the humans on Foresta wiped out by the planet's robots, and later activates the Doomsday System in an attempt to destroy the entire planet.
  • 'Sun Jewel' arc: Kurenai Kogetsu, aka Madam Kurenai, was a slave freed by the heroine Valkyrie. Rather than return to her lost daughter Homura, Kurenai married the slaver Baron Mordo and murdered him to take over the planet Sun Jewel. Running the world as a horrific tyrant, Kurenai uses an orbital cannon to vaporize anyone who defies her and amuses herself via sadistic games such as burning a model's face off and using him as a broken pet. Upon the rebellion of the mining districts, Kurenai decides to exterminate them all, including her own daughter, simply to show she is not to be defied and to punish them for still honoring Valkyrie's memory.
  • 'Lendard' arc: Cure is a member of the Oración Seis Interstellar who is secretly responsible for three of the Oracion Seis Galactica's rise to power. Cure is also the one behind most conflicts of the Sakura Cosmos and Aoi Cosmos arcs, as he gave Drakken and Nero their powers, thus being behind 200 years of a planet's population being drained, the lives lost during the Aoi war, and the creation of Deadend Crow, an enormous Titan Android who has killed millions of people. When confronted by his ally Holy, a survivor of "Bloody Atmos Day Incident" by the hands of Crow, he blasts her in the stomach and admits he gave Drakken, Nero, and Crow their power so he could create villains in order to justify the existence of the Oración Seis Interstellar. Cure is willing to sacrifice anyone so he can maintain a disturbed balance of good and evil. uncaring for all the lives taken in the process.
• Elfen Lied: The unnamed hitman is a sadistic, pedophilic monster hunter. To find Lucy, the hitman mutilates, then rapes, a silpelit diclonius, leaving her powerless and without her vocal cords to be used as a radar system. Hunting for Lucy, the hitman tries to rape her human friend, the defenseless teenage girl, Mayu, disgusting even his fellow Blood Knight hitman, Bando.
• Engage Kiss: Asmodeus is an ancient demonic being responsible for several of the events of the series. Desiring to create a bridge to unleash its demonic brethren on the Earth in a faux bid for "harmony", Asmodeus strikes deals with any human it encounters, transforming them into the "Demonically Possessed", or D Hazards. After healing Miles Morgan's ill daughter in return for his undying loyalty, Asmodeus kills and replaces the wife of Isamu Ogata to conceive a Half-Human Hybrid named Kanna. When Ayano Yuugiri and Sharon Holygrail attempt to thwart its plan, Asmodeus tries strangling Ayano to death and tries to break Shu's mind by taking on a crude replica of his mother.
• ERASED:
  • The Serial Killer, Gaku Yashiro, is the intelligent and gleefully sadistic murderer driving the plot forward with his killings. His cruel tendencies arising as a child who alleviated his boredom by drowning pets and luring young girls to his rapist older brother, the killer eventually murdered said older brother and gained a taste for killing, primarily of young children. As an adult carrying out his long-time fantasies of killing dozens of children and framing innocent people for the crimes, the killer flings his fiancée out of a window when she becomes suspicious of his crimes, and stabs Sachiko Fujinima to death when she realizes his true identity. When Sachiko's time-traveling son Satoru tries to thwart his crimes in the past, the killer tries to drown Satoru before murdering his way into a political position solely to allow himself easier access to potential victims. In his final confrontation with Satoru, the killer tries to drown the man's close friend Kumi while forcing Satoru to watch, before attempting to evade capture for his crimes by burning himself and Satoru alive, bragging even in defeat how he has done nothing morally wrong, merely indulged in a hobby he truly enjoyed.
  • The unnamed, manga-exclusive, and flashback-only older brother of the killer manages to stand out as horrific and monstrous despite only appearing in one chapter. A sociopathic bully, the brother regularly assaulted his own little sibling and other kids at his school. Showing his true monstrosity, the brother formed a partnership with the willing killer where, after the killer lured little girls to him, he would rape them, a process that went on for years and resulted in dozens of rapes. When the brother accidentally strangled one of his victims to death trying to keep her from calling for help, he tried to frame his younger brother for the crime, showing no regret or empathy for his victim. Though only a teenager, the brother made his mark as the most monstrous character in the story along with his brother.
• Erin: Duke Damiya, in the anime, is the scheming nephew of the High Queen Harimiyah of Shin-Ou, and seeks to take the throne for himself. To this end, Damiya has Harimiyah assassinated, making his niece Seimiya the new queen, and frames her beloved Shunan for the incident, which makes the already tense situation between the nations Shin-Ou and Tai-Kou reach its breaking point as open war begins. Slowly isolating Seimiya from those who could help her, Damiya manipulates her into agreeing to marry him for political power. Blackmailing heroine Erin into helping him weaponize a beast called the Ouju by threatening a school of children, Damiya begins having obstacles assassinated, only to poison his loyal assassin once the task is done. Seimiya reveals that Erin has provided her with proof of Damiya's treachery and orders his arrest, preparing to offer terms of peace with the Taiko's people. Unfortunately, Damiya has already given the order for his private forces to take the Touda and massacre the incoming Tai-ko forces, thus kick-starting a full scale war between the kingdoms, during which he plans to use Erin to train him a massive and ravenous army of Ouju to dominate both kingdoms at their weakest.
• Eureka Seven: Dewey Novak put his top fighter Anemone and multiple girls like her through torturous experiments to make them Tyke Bomb soldiers. Anemone was the only survivor, but her mind was severely damaged. In order to gain support for his war efforts, Dewey engineers enormous levels of civilian casualties, using the Coralians as a scapegoat to convince humanity they cannot coexist and must wipe out the Coralians. His motivation is that his world domination plans have no place for the Coralians. He is also motivated by a petty grudge with his younger brother Holland, and he even prepared to destroy the universe should he fail.
• Fang of the Sun Dougram: Helmut J. Lecoque is a heartless politician from Earth who serves as an aid to the hero Crinn's father Donam Cashim. Continuously pushing Cashim to be more brutal with the Deloyer rebels, when Cashim finally dies, Lecoque assumes command and proceeds to make the war bloodier than ever, committing war crimes and instituting brutal internment camps for prisoners while getting countless innocents and soldiers killed. Merrily intending to escape justice by making the figurehead leader Carmel take the fall for his crimes, Lecoque orders the targeting of civilians to draw out the last of Deloyer's resistance, intent on rising to greater power no matter what he has to destroy.
• Fantasies, by Gen Osuka: Philippo, leader of the Bloods, is a Fantasy user whose model is "Vampire". Killing his rivals, Philippo uses their organs for the black market trade while also being a vicious Serial Killer on the side who drains women of blood. After killing a rival, Philippo takes the women to drain of blood, and even feasts on a random woman fatally later. Philippo, upon incurring the wrath of the benevolent gang Junk Hole, decides to come and massacre everyone in their territory before taking all the women to feed his depraved thirsts.
• Fantastic Children: Georca is the brother of the King of Greecia. Desiring to take Greecia for himself, Georca sends his men to bomb the king's quarters, which ended up killing the princess. Overhearing the scientists' conversation regarding the princess being turned into a living weapon, Georca kidnaps one of the scientists and then lures the princess by using her mother as a bait. He then proceeds to mentally torture the princess, resulting in her uncontrollable powers being activated, in turn causing Greecia's destruction. When the Princess calms down after using her power, Georca then proceeds to attack the castle in order to retrieve the princess. It was also revealed that he is the one behind his son's Start of Darkness by beating his mother in front of him.
• Fatal Fury: Devil Street of Horror:
  • The Martial Emperor, born three millennia ago in China, desired to advance his skills beyond mortal comprehension and threw himself into battle to kill countless people. At one point, he even annihilated an entire nation's army on his own. Making a pact with demons, the Martial Emperor entered a deep sleep with instructions on sacrificing martial artists to him to restore him. Upon his awakening, he begins absorbing the life from fighters all over the world and consumes his own loyal followers before announcing his intentions of ravaging the world and making it into a new hell where countless die so that he can feed his hunger for battle
  • Geese Howard, in stark contrast to his game counterpart, is a cruel demonic overlord who uses his army of demons to conquer villages and enslave their people. Desiring to bring the Martial Emperor back to life in order to rule the world with him, Geese orchestrates a fake fighting tournament where the winner is chosen as a fuel source to increase the Emperor's power. Kidnapping Andy Bogard—whose master Geese killed years prior—Geese hooks him up to a machine and promises him the death of his friends. When he finds Terry and the others getting closer to the Golden Temple, he sends Jirai to stop them, letting him mind control Andy to fight his brother and friends. Once the gang makes it to the Golden Temple, Geese tries to kill them, hoping to stall long enough for the Emperor's incomplete reawakening.
  • Liuo Himmler is the sadistic, cyborg leader of the Devil Street's Fourth Dragon Factory District. Appointed by the Martial Emperor, Liuo has his goons kidnap men and children to be used as slave labor for manufacturing weapons. Executing workers who attempt to escape, he threatens those who try to run away with the promise of killing three returned child slaves. Getting into a fight with Joe and Bear after promising to make them his slaves, Liuo tries to kill the returned children with a spike chandelier.
• Fire Force:
  • Sister Sumire Sugita poses as a kind, grandmotherly figure to the young nuns of St. Raffles Convent, but in reality, her true allegiance lies with The Evangelist as a member of the White Clad. A businesswoman who lived before the First Great Cataclysm, Sumire's misanthropy led her to follow The Evangelist's desire to cleanse the world. Since the failure, Sumire has experimented on various individuals to rediscover the Eight Pillars, of which she is one, most notably the convent's children. Subjecting them to lifelong agony as Infernals that caused the church to explode, Sumire emotionlessly reveals the truth to her former student, Hibana, before returning to the White Clad's side to finish what she started, even sacrificing her life to empower her god bent on a twisted version of salvation.
  • Giovanni, initially a doctor with the heroes, is a mole for the White-Clad and one of the most depraved of the lot. Inheriting a mission to bring the Cataclysm to earth, Giovanni steals countless bodies with the hosts dying in the process and Giovanni inevitably moving on. Proving a sadist who constantly delights in the pain of his victims, even sacrificing his own to get to the heroes, Giovanni finally steals the body of the young boy Yu and initiates a new Cataclysm so that all living themes may become fuel for a new inferno.
• Flame of Recca:
  • Kōran Mori is a hideous millionaire who believes he can do whatever he likes thanks to his wealth, and desires invincibility and immortality in order to enjoy his wealth forever. To this end, Kōran abuses his adopted son, Kurei, having killed Kurei's lover Kurenai, and blackmails him into service with a bomb inside Kōran's own wife—Kurei's loving adoptive mother. Kōran runs brutal underground fighting rings that routinely result in horrible deaths, and manipulates fighters into Training from Hell where their loved ones die, while he employs multiple insane murderers and uses them to kill innocents. After Kurei loses the tournament, Kōran reveals he created an Opposite-Sex Clone named Renge, after dozens of failed attempts led to tormented clones being either killed, or emotionally abused by Kōran for being "failures", and attempts to detonate the bomb in his own wife, gleefully declaring he will destroy whatever Kurei loves. After achieving immortality, Kōran becomes a Humanoid Abomination whose desires for food and sex have "merged," which he satisfies by raping and eating innocent women by the dozen. Along with continuing to abuse Renge both sexually and emotionally, Kōran ends up devouring her to steal her soul and power, even as she begs for his mercy. In the end, Kōran Mori is a wholly irredeemable beast of a man who lives for nothing save his own whims and pleasure.
  • Kaima is the creator of Tendō Jigoku and, much like Kōran Mori, desires immortality to satisfy his one lust in life—killing as many people as possible for fun. It was also revealed that he created evil Madogu, mystical objects that grant special powers; the Tendō Jigoku would grant immortality—by using children. When Recca rejected his offer, Kaima took the chance to gloat that he would never give his power to anyone with redeeming qualities like Recca and then proceeded to merge with Kōran Mori, turning them into a monstrous being that satisfies their "lusts" by raping and killing women. To create their own army, Kaima and Mori butcher dozens of innocents, then turn them into their mindless zombie slaves that serve them unquestioningly. Finally, they planned to create a dystopia based on devouring most of humanity, waiting until a few are left to repopulate the Earth, then starting the process all over again for all eternity.
  • Mokuren Nagai is a Serial Killer who loves to target women with nothing less than a Slasher Smile and cheerful glee. With his power over plants, Mokuren invents new ways to kill his victims, such as impalement with branches, creating carnivorous plants to devour them or horrible torture. Mokuren convinces his former kid sidekick to let down his guard before trying to devour him with a plant as well. Gradually gaining a seething hatred for Recca after Recca defeats him, Mokuren sinks further into depravity and evil. He develops a relationship with fellow evil teammate Mikoto, only to betray and murder her the moment she's inconvenient to him, coldly saying he never loved her and defeating Recca is all he cares about. Even after his death, the narrator discusses what a monster without honor, morality or humanity he was.
  • Sōkakusai of the Ura Uruha is the user of the madōgu Tamasui no Tsubo, a massive and magic urn. Sōkakusai stalks young women to demand their affections and upon being spurned, he traps them in the urn to die slowly and painfully, with a massive amount of corpses shown in the waters of the madōgu.
• Forest of Drizzling Rain: The first Ogami-san, though seen as the hero of old who protected the village, is in fact behind the Kotori Obake's horrific past. To satisfy his lust under the guise of punishing criminals who defied the laws of the village, the first Ogami-san created a system where their wives and children would be sold into sexual slavery, imprisoning them in a dungeon to hide their suffering from the villagers. After falling in lust with an unnamed village woman, he falsely accused her of manipulating men to commit crimes so he could slaughter her husband and son, then imprison her in the dungeon, as "punishment" for her non-existent crimes. He and his men raped and impregnated her, mocking her all the while, then killed the fetus to make her suffer even more, ultimately leading to her snapping and becoming the Kotori Obake who would eventually murder them all in revenge. Despite portraying himself as a hero working for the goodness of the village, the first Ogami-san is rightfully described by one of his descendants as being nothing but a hateful tyrant.
• Fourteen: Grand Master Rose, the most powerful businessman in recorded history, desires eternal youth more than anything. Draining the essence of children and eventually his own clones to keep a youthful appearance, he even order kill anyone that saw his wrinkles. When the apocalypse starts, Grand Master Rose helps the world governments find and later capture the mysterious doctor Chicken George, using an actress to trick him. After capturing George despite the actress genuinely loving him, Grand Master Rose forces him to create a immortality formula claiming that he wants it for the sake of humanity, by threatening his loved ones and starving him. After George creates a functional serum, Grand Master Rose uses it and becomes a sapient mass of cells able to create humanoids later known as "Commodities", that he sells as expendable slaves. As the apocalypse continues, Grand Master Rose escapes Earth's destruction by putting his brain inside a female infant clone known as "Nobara" that infiltrates into the spaceship containing the last surviving children, using her appearance to trick guards before betraying her allies. Brainwashing the guards, "Nobara" forces the children to obey her; crushes the head of a dissenter; tortures America Young; abuses her own guards; and when the dissenters escape and she's insulted, "Nobara" orders a game of "Hide and Murder" with the male children. Planning on stealing America's body and turn the children in his own harem, Grand Master Rose risked the survival of humanity itself multiple times for the sake of his ego.
• Fractale: Barrot is one of the highest-ranking figures of the Temple, a society which has enslaved the world to the Fractal System, and is the second-in-command to Archpriestess Moeran. By nature a perverted sociopath, Barrot is the current head of the Temple's cloning project, which has manufactured hundreds of thousands of identical clones all under the name of Phryne for the purpose of experimenting on them to see if they are worthy to become the key to restarting the Fractale System; any that do not meet the qualifications are disposed of. Barrot has defiled and disposed of these clones over and over, and fixates on one particular Phryne clone, raising the Phryne as his own daughter and subjecting her to sexual attentions. After Phryne escapes from the Temple, Barrot orders a wide search for her, fully willing to assault a village linked with Lost Millennium and pay immoral clients should they be capable of turning Phryne in. Barrot later retrieves Phryne, and forces her into a virginal check under the threat of Clain's life, and later boasts that he himself raped Phryne in order to emulate the experiences of Phryne's first body and make her suitable to become the key, gloating that she was "the finest vintage I ever matured." Barrot is narcissistic enough to view himself as the world's savior for his immoral research, and takes in any opportunity to soak in his own ego and sick sense of self-satisfaction.
• Freesia: The Professors are a trio of powerful politicians behind the dystopian dictatorship that rules parts of Japan, controlling the media and isolating the country to keep a façade of normality while sending thousands of young men to die in a Forever War to keep their power. Eventually taking funds from the prisons to finance their war, the Professors "solve" the issue by creating the Vengence Act, allowing the families of victims from violent crimes to hire legalized mercenaries named Enforcers to kill ex-convicts even if they are successfully re-inserted in society, creating a system where Enforcers regularly torture their targets and injure innocents in their sadistic games, leading to a massacre carried by a rogue Enforcer. When the opposition figurehead Keita Yamada threatens to shake the political order after the scandal, the Professors order the Enforcer Agency to execute him—despite his apparent innocence—before finding Keita's secret crime and legalizing his execution in a mall, causing a bloodbath where many civilians are gunned down by the Enforcers.
• Freezing:
  • Isabella/Isabelle Lucas was recruited as a Pandora comparatively late to other Pandoras. Formerly a nurse before joining the corps, it was revealed that Isabella had killed multiple infants in her care to satisfy her bloodlust. When the attack on West Genetics begins, Isabella attacks Pandora and bystander alike, gleefully murdering everyone she sees. When one Pandora is able to give her a fight, Isabella promptly injures her Limiter partner's leg and attempts to rape him, using the life of his partner as leverage.
  • Isuzu Sawatari, one of Isabella's teammates, is a charming, friendly and sweet woman whose life is "plagued by tragedy" on the surface. Underneath this façade lies a sadistic sociopath whose MO for murder is to lure men into her bed to enrage their female super-soldier Pandora partners, so Isuzu can kill them in "accidents" or self defense when she is confronted by them. Having continued this practice with civilians, Isuzu is recruited to murder the scientist Gengo Aoi with three other Pandora criminals. Isuzu agrees to the mission in return for a guaranteed "license to kill", and shows her sadistic side by massacring multiple young Pandoras, and even kills one of her own teammates after crippling the other woman. Upon finding Gengo Aoi, whose bodyguard is her old rival Suna Yi, Isuzu provokes Suna into a fight by attempting to torture and rape Gengo so she can finally slaughter Suna in a straight fight.
  • The wicked High Priest of El(u)ka, Ibanyle, abuses the very balance itself for his own pleasure and hedonism. With the balance thrown out of whack, Ibanyle torments countless souls and fuses them into tortured Nova so he may experience his world's Pandoras, or Rounders, fighting them, while also taking advantage of his status as one of the few males around to keep a harem and engage in frequent orgies, while expressing a desire to rape and abuse his world's Satellizer. Attempting to have Kazuya Aoi gang raped by his concubines and expressing glee when he learns that Earth's destruction thanks to his carelessness can only help preserve Elka, Ibanyle, upon putting down the rebellion by his consort Maria, declares he will turn Maria into an abused concubine, caring only for his own pleasure and power.
• Fukashigi Philia: Isumi Yuunagi, seemingly the kindly man who took Tasuku in after the death of his parents, is actually a murderous human trafficker whose Gift is "Will Over Memories". Before gaining his Gift, Isumi profited off human misery and is chronologically introduced trying to strong-arm a man named Sentetsu into selling his stepson to be trafficked to pay off the debts Isumi has forced upon him. A violently possessive father of his only child Yusuzu, Isumi slaughters a kid, Tasuku, and his entire family for being nice to Yusuzu during a rainstorm. Tasuku's Reality Warping sister Nao brings Isumi back with his Gift, which he promptly uses in tandem with Tasuku's gift-—rewinding time-—to brainwash Nao and a resurrected Tasuku as his slaves, murdering Tasuku over and over and over again while forcing Tasuku and Nao to enjoy it. Even when he's finally killed, Isumi tries to overwrite the personality of his killer to replace it with his own, and from there brainwashes Tasuku into remembering Isumi as his kindly parental figure. Isumi is monstrous even to Yusuzu, using his powers to curse everyone who talks to his daughter to forget her, and even attempting to stab her to death when she ultimately foils his plans.
• Full Metal Panic! anime: These two bloodthirsty members of the counterintelligence Amalgam organization are a cut above for cruelty:
  • Gauron, aka Mister Iron, is a brutal mercenary and the Arch-Enemy of protagonist Sosuke Sagara. Having killed all of Sosuke's comrades in a war-torn country, Gauron also repeatedly attempts to force himself on the minor. In present, Gauron shows his brutality on missions he is assigned to, killing subordinates for questioning him, hijacking an airliner while threatening the high school passengers, and kidnapping one passenger to subject her to painful experimentation. Returning later working as a nuclear Arms Dealer, Gauron happily slaughters Sosuke's squad trying to stop him and goes on to hijack a submarine, intending to fire its powerful missiles lest his enemies give in to his demands. Corrupting two twin teenagers into following his twisted will, Gauron uses them to target Sosuke and his Love Interest and even when lying completely immobilized, tries to draw Sosuke into one final trap to kill them together.
  • The Second Raid anime: Mr. Gates, aka Mister Kalium, is assigned to the head of Amalgam's Execution Squad and is a lunatic who kills his own followers for any slight or just to make a cruel joke. Attempting to ambush the heroes, Gates targets a public place, uncaring for the innocents caught in the way. Sexually depraved as well, Gates holds teenage twins Yu Fan and Yu Lan under his thumb, possibly subjecting them to assault, and when one is killed, uses her body as a puppet to viciously mock the surviving sister.
• Fushigi Yuugi: The Emperor of Kutou is a draconian ruler who leads his armies on campaigns of extermination and conquest, having done so to Nakago's village where Nakago's people were slaughtered and his beloved mother raped by the Emperor's soldiers. Seeing potential in Nakago after his power allowed him to slaughter the Emperor's soldiers, the Emperor opted to turn Nakago into his own lethal weapon to cause more bloodshed. Worse still, the Emperor also turned the boy into his own personal Sex Slave after being captivated by his beauty, warping the mind of the child who would become the series's Big Bad.
• Future Boy Conan: Lepka is the ruthless Chief of Administration in Industria, one of the final bastions of humanity after war ravaged the Earth. Lepka seeks to repeat the mistakes of the past for the sake of his own power by utilizing one of the ancient warplanes that devastated Earth to conquer it. Already responsible for having branded and thrown hundreds of people into Industria's dungeons—a fate he threatens for the two young protagonists—Lepka steadily becomes worse as the plot goes on, betraying Industria's Security Council and attempting to drown thousands of innocent people to flush out the heroes, all after lying that he would save them if they caved into his Sadistic Choice. Lepka tortures the old, pacifistic Dr. Lao to the point where he goes both blind and deaf; repeatedly threatens to kill Lao's granddaughter; and he has no compunction killing his own men and abandoning them all to die when his plans go south. As a spiritual predecessor to future Miyazaki villain Muska, Lepka is unusually and totally Beyond Redemption in an otherwise idealistic series.
• Future Diary: Funatsu, though a minor villain, caused one of the most horrific events of the series. Once a member of a peaceful cult based around a young girl, Tsubaki Kasugano, who allegedly had prophetic powers. Funatsu killed her parents when they planned to disband the cult, fearing losing his power. Becoming the de facto head of his reformed cult, Funatsu allowed the members to rape Tsubaki regularly, possibly taking part himself, and drugged her to keep her defenseless against their constant assault. So intense was Funatsu's cruelty to Tsubaki that she went insane and began plotting to destroy the world.
• Future Robot Daltanious: The Commander of the Zaar Reconnaissance Fleet is Earth's first taste of the Zaar Interstellar Empire's brutality. He leads his fleet into a bloody campaign of conquest across Japan which orphans hero Kento and his friends. The Commander plans to continue razing Earth's cities and destroying any military resistance that gets in his way until the whole planet submits to the Zaar Empire. When newly awoken, Daltanious destroys one of his giant robots and the Commander mobilises his entire fleet to destroy Doctor Earl's base and personally destroy Daltanious.
• F-Zero: Legend of Falcon: Black Shadow is the ruler of Dark Million, and the always-grinning chessmaster behind every single bad event in the series. Black Shadow, atop facilitating general terrorism and abusing underlings as a course of habit, has gone to every length imaginable to prevent Ryu Suzaku from stopping him. Black Shadow creates the homicidal criminal Zoda and sends him off to homicidal rampages—at one point powering up Zoda to annihilate all of Mute City—and kidnaps Ryu's girlfriend Haruka to brainwash her into his pet assassin, Miss Killer, trying to use her to kill her own boyfriend. Black Shadow carbonizes Miss Killer when she finally breaks free of Black Shadow's spell, and gleefully torments Ryu with her petrified body. Black Shadow, in the finale, reveals his glorious dream that his every waking moment has been dedicated to: Using his Dark Matter Reactor, Black Shadow throws the entire galaxy into death and destruction, to precede him creating a new Big Bang to annihilate the old universe and create a new one of pure evil on top of it.

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