open/close all folders
Debuted in Parasite Eve (the novel)
A mysterious, ancient evil that wants to reverse humanity's symbiotic relationship between the nucleus (banks of genetic information that dictate what cells grow where and when) and the mitochondria (organic power plants that fuel cellular activity). To this end, she takes over the body Kiyomi Nagashima, wife of mitochondrial expert Toshiaki Nagshima, and forces her to crash her car. Toshiaki cultures some of Kiyomi's liver cells, giving Eve a place to grow a body, and one of Kiyomi's kidneys is transplanted into fourteen year old girl Mariko Anzai, whom Eve mutates the womb of so it can give birth to the Ultimate Being. After obtaining some of Toshiaki's sperm and implanting it into Mariko, Eve dissolves, unable to keep up with the energy output needed to sustain her own body.A second, unrelated Mitochondrial Eve (possibly, see Continuity Snarl) takes over the body of New York opera singer Melissa Pearce in the Parasite Eve game with the same goal as her predecessor of creating the Ultimate Being. Eve-2 dissolves a solo performance crowd at Central Park into raw genetic material and allies with Melissa's former doctor, Hans Klamp, to procure sperm for her Ultimate Being. Aya Brea fights her several times around New York, but is unable to seriously stop her plans.The original host of the second Eve is actually Maya Brea, sister of Aya Brea, who was in a fatal car crash and had her kidney donated to Melissa and her cornea to Aya.
- Barbie Doll Anatomy: Several of Eve-2's later forms feature breasts that lack nipples, along with creative obfuscation of the pubic area. Strangely, artwork of Eve-2 in the official Parasite Eve artbook shows her having nipples, although the pubic area is still obscured.
- Big Bad: Of the book and the first game.
- Bishonen Line: Eve-2 hits this plateau in her evolution fairly quickly and to an extent repeatedly, and for a freakish mutation, she looks disturbingly Fetish Fuel-worthy. Her final form is a lot more humanoid and angelic than her previous forms.
- Blob Monster: When Eve-1 grows she is described as giant piles of bloodless flesh.
- Body Horror: Eve-1 is this, while Eve-2 mostly inflicts it on others while riding the Bishonen Line. Some aspects of Eve-2's body are still very horrific, however, such as her first form's 'tail' and freakishly large hands.
- Break Them by Talking: Eve loved to direct this towards Aya, hoping to force Aya to see things her way and join her or simply give up.
- Continuity Snarl: The only way the second Eve could be directly connected to the Eve-1 is if the Mariko in the book is the same Mariko that's Aya and Maya's mother. And that does not work because the events of the book take place in 1985 and Aya and Maya's mother died in the 70s.
- Dangerously Genre Savvy: Eve-2 has several shades of this throughout the game. She knows Aya has potential power and would rather convince her to join her side to take over the world. When that doesn't work, Eve-2 attacks the NYPD precinct that Aya works at in order to distract her while Eve-2 runs off to a hospital to get a sperm sample so that she can impregnate herself and create the Ultimate Being. When Aya shows up at said hospital, Eve-2 cuts the cables on the elevator that Aya was in to make her fall to the basement and then cuts the power to trap her there. If you try to take the stairs, Eve-2 destroys them to keep you in the basement. This buys Eve-2 enough time to get the sample and escape.
- Evil Laugh: Her dialogue suggests this despite the fact that there isn't any voice acting in the first game. In the cutscene where she smashes the piano she was playing, however, she does let out a rather high-pitched laugh after mutating into her first form. It's rather chilling.
- Fan Disservice: See Barbie Doll Anatomy above. Especially Eve-2's gestating form from the museum encounter in Day 5.
- Femme Fatalons: Eve-2's hands.
- Go Out with a Smile: A villainous example, as after being defeated by Aya, she flashes a smile at her just before she dies, since she's already given birth to the Ultimate Being.
- Green Eyes: When Eve-2 takes over Melissa's body, her eyes turn from brown to green. They stay this color from then on out.
- Hannibal Lecture:
- Eve-1 gives one of these in a rhetorical question form at a lecture on mitochondria and a more direct one at a different lecture.
- Eve-2 loves giving these during her We Can Rule Together speeches to Aya, rambling about how the nucleus is long overdue for a subversion of its smug superiority over the mitochondria.
- Hoist By Her Own Petard:
- Eve-1: Never thought that male mitchondria could actually be a threat.
- Eve-2: Never expected that the evolution she so fervently sought would produce her own superior on the food chain.
- Horned Hairdo: Eve-2.
- Living Bodysuit: Kiyomi Nagashima, Mariko Anzai, and Melissa Pierce.
- Monster Is a Mommy: She wants to create an Ultimate Being by giving birth to it.
- Multi-Armed and Dangerous: One of the forms she assumes when Aya engages in the last battle with her on the collapsed Statue of Liberty.
- Playing with Fire: Her "aura" immolates people and animals (the ones that don't melt into goo or mutate).
- Power Floats: Both Eve-1 and Eve-2 are capable of levitation.
- Puppeteer Parasite: Hence the "Parasite" Eve.
- Recurring Boss: She's fought many times throughout the game, in various forms.
- Shapeshifter Mode Lock: Eve-2 makes several changes throughout the first game and these changes appear to be permanent, as she is never shown reverting back to previous forms.
- Took a Level in Badass: Eve-2 is way more powerful than Eve-1. She can set people on fire and mutate them, while Eve-1 was only able to set people ablaze.
- Voluntary Shapeshifting: Eve-1 is capable of this. Her favorite form is Kiyomi. Eve-2 sticks with a mutated Melissa, but does not show any sign of being able to shapeshift.
The Ultimate BeingEve's "child", a human/mitochondria monster hybrid that has all of Eve's powers and complete control of its genetic code, that Eve wants to lead the mitochondria revolution. Eve succeeds in her goal of creating the Ultimate Being, but doesn't count on the male mitochondria from Toshiaki's sperm to rebel against Eve's mitochondria, causing the whole thing to self-destruct.The second Eve also wants to create an Ultimate Being and spends most of the game attempting to create and give birth to one. In the normal game (Day 6), Eve dies but the being is born anyway, since she implanted it into the mito-mass at Liberty Island. Is the final boss of the regular scenario.
- Bald of Evil: Especially so in the video game where each form he takes always has him bald.
- Bigger Bad: Eve may be the main threat, but the Ultimate Being is the final one.
- Eldritch Abomination: Dear god, there is barely anything human about it despite its appearance.
- Fetus Terrible: The second Being's first form.
- Final Boss: Is this in the first game.
- Ultimate Evil: Starts off as an overgrown deformed baby and then evolves several times throughout the battle with each form becoming less humanoid and more freakish and unexplainable.
- Ultimate Life Form: Was a part of Eve's plan to have a child that could rival her power and conquer the world without it having any of the weaknesses that the previous Ultimate Being (novel) had.
- Weaksauce Weakness: The first Ultimate Being's weakness is her/his dad's normal vanilla mitochondria. The second Ultimate Being that debuted in the game is weak to Aya's mitochondria via bullets laced with Aya's cells.
Debuted in Parasite Eve (the game)
Voiced by: Maaya Sakamoto (JP) and Yvonne Strahovski (EN)
A 25-year-old police officer whose life changes when a date At the Opera Tonight (tonight being Christmas Eve 1997) goes horribly wrong. As the only person to not not-so-spontaneously combust upon the awakening of Mitochondria Eve, she struggles to understand and rein in her own bizarre powers while racing to stop Eve from giving birth to the Ultimate Being and destroying and/or forcibly evolving humanity in the process. She's immune to Eve because they share donor organs from her twin, Maya. More on that further down.Aya returns in Parasite Eve 2, set three years after the events of Parastie Eve as an ace operative of the FBI's anti-mitochondrial mutant task force, MIST (Mitochondrion Investigation and Suppression Team), formed following reports of Eve's mutated animal minions spreading out from Manhattan. Aya's journey to destroy the newly-monikered "Neo-Mitochondrion Creatures" (NMCs) and put a seal on her own unpredictable powers leads her to Los Angeles. However, an investigation into an NMC outbreak near the ghost town of Dryfield, Nevada hits closer to home.Aya is the star in The 3rd Birthday but, apart from her name, she remembers nothing about herself or her past. When the CTI (Counter Twisted Investigation team) found her, she was wearing a bloody wedding gown outside the St. Thomas Cathedral in Manhattan, either just before or just after her own wedding. After taking her into custody, the CTI realized her abilities allowed her to dive into a human's past consciousness. Understanding that this was humanity's only chance against the space and time-defying Twisted, the Overdive Investigation Unit was formed to develop a way to use Aya's powers against them.Except this isn't Aya at all. It's Eve, from Parasite Eve 2, in Aya's body, the result of a failed Emergency Transformation. As a result, she actually regains a mix of both her actual memories and Aya's, resulting in a huge Tomato Surprise.
- Action Girl: Started off as a cop in the first game, becomes a specialized FBI agent in the 2nd game, and then becomes a CTI agent in the 3rd game.
- Bare Your Midriff: Aya's default outfit in 3rd is a purple vest about one size too small.
- Big Damn Hero: At the very end. of 3rd.
- Bizarre Human Biology: Aya possesses a more benign/passive form of the "evolved" strain of mitochondria serving as the the first game's Big Bad, which are not only a self-aware Hive Mind that can hijack their "hosts" and act like The Virus, they possess actual superpowers, which include spontaneous combustion and Body Horror transformations!
- Blood-Splattered Wedding Dress: When CTI found her.
- But Not Too Foreign: Half-Japanese, as a nod to the novel.
- Clothing Damage: Like you wouldn't believe in 3rd. While it can be quite interesting, the more skin Aya shows the more damage she takes.
- Combat Stilettos: Her high heels in the first game's beginning. She even goes into the New York sewers in them! Justified as she was on an opera date when Eve/Melissa first manifested and attacked the audience.
- Cursed with Awesome: Aya's mitochrondrial powers lack the villainous insanity and Body Horror that other people in this series go through—she received the "special" mitochondria when she was still a child, and unlike Melissa, Aya's mitochondria evolved to the point where they are symbiotic with her body and work with her instead of taking outright control. However, they also keep her body younger than she really is, since a youthful host is advantageous.Aya: (looking in a bathroom mirror) Here's looking at you, kid. I look like I'm in my early 20s... It's nice... but there's a reason. It's what my mitochondria want. I never asked for this. A youthful host is advantageous... I saw this movie about a medieval knight who lived into this century. I don't want that. I'll be happy to live just one, normal life.
- Dead All Along: A trait she shares with a lot of characters in The 3rd Birthday.
- Deadpan Snarker: More so in 2 than in 1 and 3rd, mostly when you have her examine something several times. "Do I have to look in there again?" is her comment if you keep trying to make her look into a dirty toilet.
- Expy: Lessee here, beautiful with blonde hair and blue eyes, has a secret connection to the main villain who spends most of the game trolling her or trying to drive her crazy, paranoid and unsure of her past and what she is, a bit of a smartass, and has a unique genetic trait that gives her special powers. Are we talking about Aya or Cloud Strife?.
- Eye Remember: Maya's cornea (which possessed Eve's mitochondrial power) was transplanted into Aya's right eye, and Aya's visions are actually Maya's last memories.
- I Am a Monster: Her main worry in the first game. After seeing how her powers are similar to Eve's Aya freaks out and tells Daniel and Maeda to go away so that she doesn't hurt them if she does become a monster like Eve. Luckily, Daniel and Maeda stick by her and she quickly gets over it.
- I Just Want to Be Normal: Her stock flavor of angst for the first couple of chapters, peaking in an I Am A Monster-flavored Heroic BSOD.
- Elemental Powers: Which she develops in2.
- Fair Cop: Oh yes. She's caught the eyes of quite a few men. A short list includes her nameless date at the beginning of the series, Maeda, Pierce, and Kyle.
- Fairytale Wedding Dress / Pimped-Out Dress: Her wedding dress in The 3rd Birthday.
- Hyperspace Arsenal: Her gun is always a pistol in cutscenes, but may range up to and including a rocket launcher during gameplay with no encumbrance penalty.
- Hypocritical Humor: In the second game during her trip to Dryfield's grocery store, Aya will note how she refuses to touch junk food due to the large amounts of fat and calories, but she has no qualms with taking a can of soda, which is usually loaded with sugar. Soda must be related to her MP, considering the huge boost she gets from drinking it.
- The Heroine
- Iconic Outfit: Her sexy black dress from the first game's beginning is very well associated with her, despite that she only wears it for at most, an hour's worth of gameplay.
- Improbable Aiming Skills: Zigzagged in the first game: her shots would miss if the target was too far away from her, but if she was close enough, she could always hit her targets even if they were moving in fast and erratic patterns. Played straight in the second game, she's a great shot, such that she can pick the wings off of mutant moths at range. Some flavor text in the MIST HQ also reveals she got 2nd place in the most recent MIST shooting competition, losing out only to Rupert Broderick. Then averted in the third game, where she didn't even place in the top ten at the CTI shooting contest. Guess her muscle memory was also affected by her amnesia. And Eve Brea is much less skilled with guns than Aya...
- It Was with You All Along: Discovered at the end of 1.Aya: "Maya. I was always waiting...waiting for you to come home with mom. And I've always been looking for the other "me". But you were always right there with me Maya...ALWAYS, all this time."
- Killed Off for Real: Along with Eve's body to prevent the creation of the Twisted at the end of 3rd.
- Limit Break: Liberation mode, her main power in 3rd, in which Aya's powers break free of their limitations, letting her dual-wield, dance circles around enemies and fire very powerful energy blasts. Can come with a Dangerous Forbidden Technique (Inferno, which is Cast from Hit Points) if the player is inclined.
- Little Black Dress: The out she wears during day 1 when she went to the opera.
- Loose Lips: During an interview with the press over the Carnegie Hall burnings, Aya winds up telling the press exactly what happened with Eve and the monsters, despite Baker telling her to keep quiet about it. Naturally, this causes confusion and panic within the media and Aya gets reprimanded by Baker for giving out sensitive information.
- Magic Knight: Skilled with any firearm, and has a collection of powerful magic (Parasite Energy) to back her up.
- Mike Nelson, Destroyer of Worlds: She created the Twisted by sheer accident.
- Mini Dress Of Power: In 2.
- Missing Mom: Her mother died in a car crash along with Maya. Aya was raised by her father.
- No Sell / Only I Can Kill Her / The Immune: Her immunity to Eve's powers makes her the only one that can fight her effectively.
- Older Than They Look: Was 25 during the first game, 27 in the second game, 38 in 3rd, looks barely 21, leading to Who Wants to Live Forever?. This is explained in that, since her evolved mitochondria have opted to work with her rather than against her (which is the defining difference between Aya and the various monsters around her), they've decided that keeping their host healthy and young is more advantageous to them than allowing her to age.
- Out-of-Clothes Experience: When she goes into Liberation mode.
- Pop-Cultured Badass: Casablanca and Indiana Jones and the Last Crusade in the same sentence, while observing herself in a mirror and contemplating turning into a hundreds of years old knight. While mourning that her car was destroyed by monsters she brings up naming it Christine and, naturally, makes numerous references to Final Fantasy.
- Salt and Pepper: Aya and Daniel. With Rupert in the second game.
- She's Got Legs: Her dress in the first game has a nice long slit up its side. Then in the second game her outfit when arriving at Dryfield has a pair of knee-high boots and some pretty short shorts that show off her fantastic legs.
- Shout-Out: One of her alternate costumes in 3rd is Lightning from Final Fantasy XIII. Lightning also has Aya as an alternate costume in Dissidia 012 Final Fantasy.
- Small Girl, Big Gun: She can equip large rifles and finds a rocket launcher about 3/4 into the game. In the sequel one of her unlockable weapons is a portable railgun that sends her back a few feet whenever she fires it!
- Stripperific: In 3rd although she always wears her default outfit in cutscenes, some of the other outfits that she can wear are quite revealing, and that's before taking damage.
- The developers Lampshade this with her maid costume-they point out she's wearing it "for fun".
- Tomato in the Mirror: She isn't who she thinks she is in 3rd.
- Who Wants to Live Forever?: Mentioned if you check the bathroom mirror in her motel room in Dryfield. This is also how you know why she doesn't look like an old crone at the ripe old age of 27.
Daniel "Bo" Dollis
Aya's partner and Black Best Friend; combined, the manual refers to them as the "Father and Daughter Team" of the NYPD's 17th Precinct. His introduction is a Dynamic Entry that sets the tone for his take-no-nonsense approach to the Eve case, along with his determination to thwart any mundane threat that sets its eyes on Aya or his son Ben.
- Alliterative Name
- Amicably Divorced: Despite appearances, Daniel and Lorraine remain close. He takes her death as hard as any loving spouse would. It turns out that Lorraine was considering patching their family back together.
- Angry Black Man: Becomes very pissed off at the antagonists for not only putting Ben's life in danger, but for also killing his ex-wife whom he planned to reconcile with so they could become a family again.
- Badass Normal: Despite not having special abilities like Aya, it doesn't stop him from helping her out when it's called for and he kicks absolute ass when he does.
- Big Damn Hero: Pulls off a spectacular one when Aya is at her wits end on how to kill the Ultimate Being. Daniel takes the special bullets Maeda made for Aya, leaps out of the helicopter, catches on fire mid fall, and hurls the magazine towards Aya (who somehow manages to catch it!) before he plummets into the ocean and survives.
- Dynamic Entry: The first of his several Crowning Moments of Awesome.
- Lethal Chef: According to Aya in the sequel, he is a terrible cook.
- Married to the Job: The reason why Lorraine left him in the first place.
- Older Sidekick: He's older than Aya.
- Papa Wolf: You don't mess with his son, even if you're are an evil sentient form of mitochondria.
- Sink-or-Swim Fatherhood: Lorraine divorced him a year before the game starts, leaving him sole custody of their son Ben.
Daniel's son, in the custody of his ex-wife Lorraine due to his long hours on the force. Initially planned to reunite the family at Melissa Pearce's Central Park solo concert, but Eve's awakening changed all that. Along with Lorraine, he was meant part of the mito-mass that became the Ultimate Being's uterus, although he survives. Likes dogs, and is quickly introduced to the K-9 unit's Sheeva, which goes about as well as you'd expect for a game reveling in its high levels of Transformation Trauma.
- Break the Cutie: The poor kid's heart is broken when he sees Sheeva transform into a monster and begs Aya to kill it.
- Missing Mom: Lorraine.
- Tag Along Kid: He was visiting his father at the police station when shit went down.
Chief of the NYPD 17th. Joined the force at about the same time as Daniel, and still maintains casual terms with him despite their difference in rank. Takes care of Ben while Daniel and Aya are on the scene in Central Park, only to get himself injured protecting him from the mutated Sheeva.
- Commander Contrarian
- Da Chief: Despite not having any Cowboy Cops to his name, he's still pretty gruff - evident when Aya lets a little too much slip during a press conference on the Carnegie Hall fire investigation.
- Desk Jockey: Became one when he was promoted to chief.
- Large and in Charge: Very tall and stock, which suits him as the police chief.
- Name's the Same: Curiously, with a character from another PSX game with biology related themes.
- Shoot the Dog: Is stuck doing this.
- We Used to Be Friends: His imperious ways rub Daniel raw. They used to be partners before Kenneth was promoted.
Voiced by: Hiroaki Hirata (JP) and Joe J. Thomas (EN)
Japanese biologist and walking Infodump for the events of the novel, who hopped the first plane to New York when he heard of the fire at Carnegie Hall. After rescuing Aya following her clash with Eve at Central Park, he relates the tale of the original Eve's attempt to birth an Ultimate Being and discovers the reason behind Aya's immunity to the current Eve. Afterwards, his main role is dispenser of inventory space-wasting good luck charms, including one literal Chekhov's Gun.Maeda returns in The 3rd Birthday, once again assisting Aya with his research into the Twisted.
- Cannot Spit It Out: To Aya during the ending.
- Chekhov's Gun: Gives you a weak handgun late in the game. Combined with the bullets mentioned below, it becomes a lethal weapon against the final boss. Appears in the sequel as the Mongoose.
- Depleted Phlebotinum Shells: The Maeda Bullets.
- Infodump: for the Hideaki Sena novel.
- Non-Action Guy: Since he's a scientist and serve's as the group's exposition, he has no combat experience and wisely stays out of trouble while the others do the leg work.
Torres Owens and Wayne GarciaCaretakers of the 17th's weapons storage area. Torres is hell-bent on making sure guns are used responsibly, having sworn off using them since his daughter died in a mishap with a loaded one. This tends to make him clash loudly with apprentice Wayne, an adherent to the More Dakka school of gun control. Both provide Aya with the facilities to modify weapons and armor to increase their bonus slots, and space to store unneeded items.Wayne, not being allowed to handle the guns without supervision, takes to collecting gun trading cards instead. Feed his hobby following Torres's death during the raid on the precinct and you'll eventually be rewarded with the Infinity Plus and/or Minus One Toolkits.
- Shout-Out: They return (sort of) as proprietors of the Lindblum Synthesis Shop in Final Fantasy IX, and reprise their argument when you first walk in: Wayne believes the key to victory is superior weaponry, where Torres puts his faith in superior armor.
- Straight Man and Wise Guy: Played rather seriously.
Warner, Nix, and CathyThey're also on the force.
- Those Two Guys: Or those three guys. They serve as nothing more than background characters and they need to be saved during Eve's attack on the police precinct.
Anthropologist at the Museum of Natural History, who is mysteriously at work despite both the Christmas holiday and an evacuation of Manhattan following Eve's audience liquification event at Central Park. Oversaw the operations that transplanted Maya Brea's organs into Aya and Melissa, supplied Melissa with enough immunosuppressants to let the mitochondria in Maya's kidney take her over as Eve, and removed the mitochondria from his sperm to make it prime material for fertilizing the Ultimate Being. Apparently has been pulling a Long Con and considered a variety of potential organ recipients for creating the UB, as Lorraine Dollis is listed on the same HLA list that he pilfered from St. Francis Hospital.
- Beard of Evil: Certainly fits the mold once you know his true motives.
- Better to Die Than Be Killed: Calls on Eve to "take him" when Aya arrives to place him under arrest. He combusts.
- Don't You Dare Pity Me!: Aya rushes to his aid after Eve sets him aflame. Characteristically, the Doc sneers at her human weakness.
- Evil Genius: Par for the course when one is a scientist.
- Expy: Klamp bears striking similarities to Professor Hojo from Final Fantasy VII, which include creating monsters and assisting the Big Bad in the name of science.
- Here Comes the Science: Where Maeda was the Infodump for the novel, Klamp takes his Exposition Breaks expounding on an understanding of genetics as shoddy as Hideo Kojima's.
- Jerkass: Dr. Hans Klamp is a total snob to Aya and Daniel in the beginning of the game and dodges their questions while acting all high and mighty. Even when Daniel later on finds his ex-wife and son's name on Klamp's computer and threatens to kick his ass, Klamp coldly tells him and Aya to leave.
- He has his reasons for blowing them off: he's actually helping Eve give birth to the Ultimate Being, which becomes the final boss of the game. Which really makes him a jerk, to put it lightly.
- Karmic Death: Up and asks for one, having completed his part of the plan.
- Mad Scientist: Even before you know who he truly is, his normal self still has shades of this.
- Misanthrope Supreme: Sells out humanity for the narcissistic desire to have his male sperm used to create the Ultimate Being.
- A Nazi by Any Other Name: Wants humans and other beings eradicated so that only the strong forms of mitochondria come out on top.
- Non-Action Guy: Does a lot of scheming behind the scenes, but doesn't do anything directly (that's Eve's job).
- Xanatos Gambit: Has two plans set in motion, though the main story only shows one while the other can only be seen through New Game+. To help Eve achieve her goal, he implants some sperm into her so that she can become pregnant and give birth to the Ultimate Being without her or the child succumbing to any side effects like the original Eve and Ultimate Being had gone through during the novel. By doing this, Eve can take over the world. Should Eve and the Ultimate Being be defeated, Klamp can rely on a second Eve from Maya's body that would finish what the main Eve had started and this particular Eve is more powerful than the one from Melissia since Maya's mitochondria is stronger due to it being the purebred.
Is dead. Aya keeps having visions and flashbacks of her as she pursues Eve, though. Is also the Bonus Boss.Aya's visions are due to having received a transplant from Maya. Aya had a defect in her right eye since birth, and received Maya's cornea as a transplant. Which is how Aya will later in life acquire her mitochondrial powers.
- Always Identical Twins: The character models for Maya and young Aya are dangerously similar, if not recycled outright.
- Death by Origin Story: She died before the start of the story.
- Tragic Monster: Her body possessed the most evolutionary form of mitochondria, which led her to be host of the Original Eve.
- True Final Boss: It's Maya's body possessed by Eve's mitochondria.
Debuted in Parasite Eve II
Rupert BroderickThe new Daniel. Still black, still badass, and about the same aptitude at dealing with NMCs and twisted humans alike.
- Badass in a Nice Suit: Rupert is always well dressed...be it at the office or in the field.
- Badass Normal: He's pretty much a One-Scene Wonder. He saves Aya from an ambush early in the game and unloads a ton of lead into the first Stranger, but sadly, he's wounded and out of commission for the rest of the game.
- Bald of Awesome: Only emphasizes how bad ass he is on duty.
- Black Best Friend: Unfortunately, despite his Establishing Character Moment being a badass with a huge Hand Cannon, he's out of the picture for most of the game. He's probably the Hero of Another Story.
- Da Chief: In the True Ending, he takes over the MIST Office after Baldwin is arrested for his treachery.
- Improbable Aiming Skills: Examining some items in the shooting range at MIST reveals he got 1st place in the most recent shooting competition there.
- It's Personal: He lost his family during the N.Y. Blockade incident. Now he dedicates his life to exterminating neo-mitochondrion creatures.
- Revolvers Are Just Better: He wields the Mongoose at the start of the game, which he gives to you only if you're on the Sad Ending route.
Pierce CarradineSomewhere between "The new Wayne" and "The new Maeda" falls MIST's resident computer whiz. Though he just plain Doesn't Like Guns, that's about the only hindrance to his assistance to Aya via Hollywood Hacking or item delivery.
- Does Not Like Guns: Lampshaded by Jodie. He's also quite bad with them, as he once tried to load 9mm Parabellum rounds into a .38 revolver (in his defense, those have only a half millimeter difference in diameter). Ironically, he oversees the shooting range at HQ.
- Hopeless Suitor: Pretty obvious he has a big crush on Aya, but she doesn't reciprocate.
- Killed Off for Real: Depending on the ending route.
- Non-Action Guy: Pierce gets himself into trouble while trying to help Aya out. Whether he survives or not depends on the player's actions. And whether you have a damn clue how to take those actions.
- Playful Hacker: Was known to do this during his spare time before he was caught by the government. Now he puts his hacking skills to use for them.
- Sunglasses at Night: Is never seen without them.
Eric "Hal" BaldwinAya's new boss. Far too impersonal to call "The new Baker". More like "The new Klamp". The MIST team like to call him Hal because his cold demeanor is reminiscent of the HAL-9001 supercomputer.
- Da Chief Lite
- Karma Houdini: If you don't get the True Ending, he apparently skips town and avoids any punishment for his actions. To get the True Ending, though, Aya calls Jodie and tells her about her suspicions, and Rupert confronts him, which leads to his arrest.
- Treacherous Advisor: Is in on the Neo-Ark Project, and may have helped procure Aya's cellular samples to assist them in cloning this newest breed of NMCs.
Jodie BouquetRuns MIST's BP shop (Bounty Points, not British Petroleum). She'll only appear near the end of the game if you're on the good ending path and it's also possible to never meet her depending on your actions.
- Arms Dealer: She's your armory/item shop at the start.
The last living resident of Dryfield (excepting his dog, Flint, and the hordes of NMCs Aya's come to clean out). A Vietnam vet with a gun collection big enough to claim the title of "The new Wayne", he helps Aya resupply during the investigation despite being compensated in some newfangled RPG currency rather than cold hard cash. After Aya's car is totaled by a herd of NMCs, he also volunteers his truck to get her and Kyle to an old nuclear shelter that may be the source of the infestation.
- Arms Dealer: During the latter half of the game.
- Big Friendly Dog: His dog Flint.
- Cool Old Guy: Despite his gruff demeanor, he means well and assists Aya to the best of his abilities.
- Crazy-Prepared: Was apparently ready for the ANMC menace, having singlehandedly booby-trapped the entire town with everything from bear traps to landmines.
- Crazy Survivalist: Subverted; he has all the hallmarks of being one, in that he's the sole living person in a town that suffered a pseudo-Zombie Apocalypse, and he's loaded to the gills with weapons and supplies, but he's hardly crazy, and is quite a friendly guy.
- Handicapped Badass: He lost a leg in a minefield during Vietnam.
- Jerk with a Heart of Gold: He's very weary around Aya do to his initial distrust with FBI agents, but he eventually warms up to her.
- Nice Hat: Wears a ten gallon hat.
- Retired Badass: He's a decorated Vietnam vet who lost a leg in a minefield.
- Shotguns Are Just Better: His Weapon of Choice.
- Wall of Weapons: the caretaker thereof.
Voiced by: Kouichi Yamadera (JP) and Jensen Ackles (EN)
A so-called private detective Aya encounters in Dryfield, claiming to be looking into strange shipments going into a nearby nuclear shelter once owned by a doomsday cult. Since he's one of the few Escort Mission escortees in the business who doesn't suck for some reason or another, Aya teams up with him to discover the shelter's connection to the new NMCs. Is a Double Agent for what's left of the Neo-Ark group, hired to bring Aya so that she could open the pathway to a runaway test subject. In turn, he was planted in Neo-Ark by the U.S. government, to pinpoint their Ultimate Being analogue for destruction via orbital railgun.Kyle returns in The 3rd Birthday. Aya keeps seeing visions of him while she battles the Twisted, but initially does not remember who he is.
- Double Agent: Kyle Madigan is actually a government agent sent to infiltrate the Ark organization, which in turn sends him to gain Aya's trust and manipulate her.
- Double Reverse Quadruple Agent: He's working with Aya, the Project and the government.
- The Mole: He's a government agent infiltrating the Neo-Ark Project.
- A Taste of Power: When teaming up with Aya for combat sequences, usually wields a cool weapon from the next shopping tier or two up.
- Shoot the Dog: Was going to kill Eve but Aya stops him, as she saw that Eve was just a scared little girl who didn't want to be used as a power/control source anymore.
- Shoot Your Mate: Near the end of the second game, No. 9 orders him to kill Aya. He fires, but he adjusts his aim to only hit her arm. This apparently satisfies 9, as he turns back to Eve to laugh... which gives Kyle the chance to shoot him in the head.
- We Cannot Go On Without You: Game Over for Aya if Kyle loses all 100 of his non-healable Hit Points. (Thankfully, he's not as screwed as he looks during the first major battle of Disc 2.)
- Yanks with Tanks: Baldwin's background check of him reveals he served for four years in the U.S. Air Force.
Number 9As the main series page calls him, "a Gunblade-slinging rooftop-hopping ape-like zombie cyborg supersoldier" who masterminds an NMC outbreak at the Akropolis shopping center and is apparently the last sentient resident of the Neo-Ark shelter - his colleagues having either become NMCs themselves in some half-assed transhuman orgy or been killed by said voluntary converts. Hired Kyle, whether of his own will or at Baldwin's request, to escort Aya to Neo-Ark so she would eventually disable various barriers that his "queen" had erected around herself.
- BFS: Though his use of a Gunblade is more memorable, he DID pack a mean randomly-on-fire machete during his first showdown with Aya.
- Dragon-in-Chief: Number Nine is the closest we have to a main antagonist, but he's not actually in charge of the big plan, just following it out. Whoever orchestrated it is long gone, either killed or turned into an ANMC.
- Elite Mook: Not all that evident, with anything resembling a Big Bad proper already dead.
- Flaming Sword: During the first boss fight with him in LA.
- Laughing Mad: He's really easily amused.
- Never Found the Body: After fighting him in Dryfield, Aya's mitochondrial power goes out of control and she sets him on fire before she passes out. Hours later, when Kyle shows up at the scene, there's no sign of 9. Of course he's not dead and he returns for the finale.
- Ninja Pirate Zombie Robot: Two and a half out of four ain't bad.
- One-Hit KO: During the first fight with him, his flame sword attack is a guaranteed kill, moreso if he's backed Aya in a corner.
- Recurring Boss: He is fought at both the Akropolis Tower and later in Dryfield.
- Vader Breath: Even when he loses his mask in the endgame, he's still breathing like this.
- You Are Number 6: Though practically revelling in the inhumanity that this trope entails.
Voiced by: Rei Okamoto (JP) and Molly Quinn (EN)
Not the same the Nietzsche Wannabe of the last game, however - this new Eve is a Mysterious Waif cloned from Aya herself and raised in isolation with the shittiest children's toys known to man - all to heighten her sense of fear and self-preservation as the eventual living engine for Neo-Ark's not-quite-an-Ultimate-Being. At least her teddy bear's halfway normal. She gets absorbed into the final boss, but Aya manages to save her. With Rupert's help, Aya adopts the girl as a sister. Eve also apparently lost most of her power, but overall she's quite well-adjusted and is going to school in the end.Eve returns in the The 3rd Birthday with an expanded role. Eve disappeared after the incident at Aya's wedding at St. Thomas Cathedral. All information on her is from Aya's personal testimony, as she doesn't appear in any records in government databases. After a particular disturbing flashback concerning her, Aya decides to use her Overdive ability to look in the past for the cause of Eve's disappearance, and hopefully learn how to save her.She is the true Player Character of The 3rd Birthday. When the SWAT team attacked St. Thomas Cathedral, Aya and all of the other attendees to the wedding were gunned down. In a desperate attempt to save her, Eve dived into Aya's dying body, and quickly killed the soldiers. However, in the process, she destroyed Aya's lingering soul. Eve, in the shock and confusion from what she had just unconsciously done (and the identity crisis of having bits of Aya's soul mix with her own), failed to return to her own body and fainted. When she awoke, she had completely lost her memories, and found herself in the care of Hyde Bohr, the head researcher for the CTI. Unknown to her, in the intense stress during the incident where she lost her memories, her already advanced cells made a huge evolutionary step, and her abandoned body decayed to create the sentient High Ones — the natural predators to the Twisted.
- Action Survivor: She was a young teenager in a woman's body who had to learn fighting from scratch — you've gotta give her credit for her tenacity.
- Brainwashed and Crazy: She was raised to be this way, amplified by being forced to wear a slave crown-esque helmet.
- Body Snatcher: Unintentionally.
- Cloning Blues: She's a clone of Aya.
- Clones Are People Too: Which leads Aya to save the girl and adopt her.
- Cute Mute: She never speaks until late in the second game.
- Damsel in Distress: She gets kidnapped by No. 9 late in the second game, and the finale consists of Aya chasing after her.
- Dead All Along: Well, her body anyway, in 3rd.
- Girls Love Stuffed Animals: Her prized possession is a teddy bear.
- Happily Adopted: Becomes Aya's little sister in the good ending and enjoys her life as a normal child.
- Healing Factor: Like her "sister" Aya.
- Legacy Character: To the Big Bad of the same name in the first game, created by a secret organization to control the NMCs and AMNCs just like how the Eve before her did things.
- Powered by a Forsaken Child: She was created to be used as a living power source for Neo Ark's Ultimate ANMC.
- The Quiet One: In her debut game, she's too afraid to speak at first, but she eventually talks with just one line.
- Tomato in the Mirror: She isn't who she thinks Aya thinks she is. Revealed at the end of The 3rd Birthday.
- We Cannot Go On Without You: There's one sequence where Aya must escort her out of a room that is slowly being filled with poison gas. Eve cannot defend herself at all, and if her HP hits 0, the game is over.
- Woobie, Destroyer of Worlds Her "play room" was deliberately designed to frustrate her, and those loudspeakers in the walls that keep Aya from using her powers? They were meant for Eve.
- If she hadn't tried to save Aya, the Twisted wouldn't have been created and Eve's own body wouldn't have decayed and evolved into the High Ones.
- Younger Than They Look: She has the appearance of a 10 year old girl, but was presumably "grown" in a much shorter amount of time.
Debuted in The 3rd Birthday
Voiced by: Takashi Taniguchi (JP) and James M. Connor (EN)Chief researcher for the CTI and head of the Overdive Investigation Unit. A friendly mentor to Aya and the other people in his unit, he is devoted to finding a way to stop the Twisted. Like EVERY character in this game, he's not quite what he seems, though. Hyde is actually one of the most powerful High Ones — a race evolved from Eve's remains that is dedicated to the eradication of the Twisted at all costs. He gathered and sub-consciously controls the other High Ones in the group.
- Adam and Eve Plot: Sort of... he wants to combine with Eve, whom he considers to be the Mother of the High Ones race and create an ultimate race.
- Body Snatcher: As a High One, he stole the original Hyde's body in the first place. Also gained the ability to Overdive when Eve dived into him near the end of the game.]]
- The Chessmaster: In his quest to go back to Time Zero.
- Dead All Along: Killed at "Time Zero", at St. Thomas Cathedral, where he was attending Aya's wedding.
- Guns Akimbo: It's hard to notice in the midst of battle, but Hyde dual wields two M4s with ease.
- Humanoid Abomination: Is a High One in disguise.
- Manipulative Bastard: Hyde Bohr's using Aya to kill High Ones to allow him to go back to time zero.
- Puppeteer Parasite: Hyde as we know him, and Eve's other CTI teammates controlled by him.
- Team Dad
- Well-Intentioned Extremist: Hyde takes advantage of the Twisted incidents to travel back to Time Zero, where he would merge with Eve and become the pioneer of a higher lifeform. Nevermind the people who died in said incident.
- A bit of Fridge Brilliance, the Twisted turn out to be this. Being the fragmented pieces of Aya's "soul" that were sent to the future due to Eve's Overdive, they abduct and kill people to make the Babels grow and merge into the Grand Babel, which would enable said pieces to travel back to Time Zero and undo those events by taking control of Aya for a little while.
Voiced by: Ryohei Kimura (JP) and Patrick Cavanaugh (EN)The chief engineer of the CTI's Overdive Unit, originally hailing from South Korea. He joined the CTI at Hyde Bohr's request.
- Heel–Face Turn: At the age of 14, he was notorious for unleashing a Trojan horse that stole sensitive information. After being arrested, he ended up with a plea bargain, and began to work for the government in order to take down the communication networks of terrorists. That earned the ire of his fellow hackers, so he survived by wiping out his personal history and starting over from scratch.
- Hollywood Hacking: His specialty.
- Killed Off for Real: By Kyle Madigan.
- Only Known by Their Nickname: We never know his real name. He purposely intended it to start over from a blank slate after a life of being a malicious hacker.
Voiced by: Hisao Egawa (JP) and Chris Jai Alex (EN)Formerly a Special Ops combat specialist, he left his squad to join the CTI team. Soon after, his whole squad was annihilated in the ill-fated Operation Red Fog. Was outside of St. Thomas Cathedral at the time of SWAT raid. He's another High One, created when Eve's body deteriorated at Time Zero.
- Dead All Along: Killed at "Time Zero", at St. Thomas Cathedral.
Voiced by: Yuko Kaida (JP) and Melinda Hill (EN)A special agent in the CTI's Overdive Investigation Unit. Her friendship with Aya is a sisterly bond. She's also a High One, created when Eve's body deteriorated at Time Zero.
- Dead All Along: Killed at "Time Zero", at St. Thomas Cathedral.
- Rival Turned Evil: Subverted. Gabrielle didn't want to attack Aya.
Hunter "Boss" Owen
Voiced by: Wataru Yokojima (JP) and Joe Smith (EN)The head of CTI. Owen suspects Aya is a Twisted, so he is constantly hostile towards her.