Playable Characters
Eika
The spirit of a miscarried child, Eika Ebisu. Instead of tears, she attacks with rocks, stacking them overhead to barrage enemies.
Her Birthright effect allows her to stack up to twenty rocks while charging, allowing her to barrage her foe with more rocks at a time.
Her Birthright effect allows her to stack up to twenty rocks while charging, allowing her to barrage her foe with more rocks at a time.
- Dishing Out Dirt: Eika stacks and throws rocks as her primary attack.
Satori
The youkai with the ability to reads minds, Satori Komeiji. Satori comes equipped the with the Psyche Eye, her Third Eye that'll permanently tames any enemy that isn't a boss with it's chargeable area of effect.
Her Birthright effect gives her the passive ability of temporarily charming every enemy in a room she enters.
Her Birthright effect gives her the passive ability of temporarily charming every enemy in a room she enters.
- The Beastmaster: Satori's play-style. She comes equipped with the Monster Manual, a book to summon various familiars, and the Psyche Eye for her ability to permanently tame enemies and give her a small damage-up for each one.
- Nerf: In the patch that overhauled the capabilities of the Psyche Eye from shooting charm tears to a chargeable area of effect, it'll automatically be disabled upon charming up to five enemies, preventing you from taming a large group of enemies.
Seija
The Amanojaku with the ability to flip anything. She effectively puts the quality system of the game on its head; any item with a high quality will come with a huge detriment (stat reduction, counter intuitive stat up, general nerfs), while on the flip side lower quality items get massive buffs that makes them worth using. She also comes equipped with the D Flip as a pocket active item, allowing her to re-roll pedestal items, typically of the opposite quality, with some items having specific re-rolls.
Her Birthright effect negates the detriments of high quality items.
Her Birthright effect negates the detriments of high quality items.
- Balance Buff: Many low quality items get tweaked when Seija gets ahold of them, some even better than the high quality items on the average character.
- Boring, but Practical: Not all zero quality changes are at the far end of the power scale, but instead offer simple changes to make it more worthwhile than usual. Boom! (plus ten to the bomb count) effectively becomes Pyro (maxing out the bomb count), for example.
- Awesome, but Impractical: The result of her ability makes generally powerful items into this. Found Tech X or Godhead? It comes with a ludicrously high shot speed that makes it hard to use effectively. Dr. Fetus? The bombs you shoot now take triple the amount of time to detonate. The D6? Now has a chance to remove items, like the Eternal D6. Holy Mantle? You are now The Lost forever. Have fun! High quality items from other Game Mods? All stats take a massive decline. She can remove most of these downsides after the fact if she acquires her Birthright (except the Holy Mantle's), though, restoring the items to as strong as they would be for any other character.
- Bad Is Good and Good Is Bad: By the nature of being an Amanojaku, she views the world in this manner, not only resulting in her gimmick, but also affects her reaction to using pills. The typical reaction to using pills is inverted in her case; bad pills such as stats down will make her thumbs up, while generally good pills make her clutch her head.
- Feed It with Fire: Cursed Blood, which normally turns damage from fire and explosions into a One-Hit Kill, instead makes explosions heal her (similarly to Pyromaniac).
- Light 'em Up: With Glaucoma, the concussive tears also result in a flash of light upon hitting a target to damage all in its radius.
- The Magic Touch: The Poop active item allows her to spawn golden poop without the need for the Midas Touch item.
- Nerf: My Reflection originally made her tears inflict constant damage for as long as it overlaps with a foe, but after the item itself was officially buffed in an update, Seija's effect on it has since been reduced to just visually changing the tears into shurikens.
- No-Sell: The Vicious Curse, which ordinarily puts an immediately active (and checking twice as often) Damocles above the user's head, turns into a net benefit for Seija, as while it does still give a Damocles, it does not damage Seija (thus not immediately starting Damocles' random checks), but also makes Seija invulnerable when the sword does fall, saving her from death. She can also become immune to fire damage with Cursed Blood.
- Stock Ninja Weaponry: My Reflection turns her tears into shurikens, with the effect only being visual ever since the Balance Buff the item recieved in vanilla Isaac. See Nerf for what it originally did.
- Smug Smiler: Their perpetual expression (unless altered by certain items) is of Seija sporting a shit-eating grin
Hourai
A hidden Player Character who's only accessible by killing the Dichromatic Butterfly in the starting room and then touching the doll that appears to become Hourai. Hourai will then replace the character you were playing as for future runs until you touch the doll again.
By dying in a specific manner once each floor, Hourai can self-revive, and generate collectibles at the cost of reducing her health, both losing a heart container and gaining a broken heart. Her Birthright removes this downside.
By dying in a specific manner once each floor, Hourai can self-revive, and generate collectibles at the cost of reducing her health, both losing a heart container and gaining a broken heart. Her Birthright removes this downside.
- Anti-Frustration Features: If you want one of your corrupted player characters back with their corruption undone, all you have to do is kill the Dichromatic Butterfly again, attack the doll that spawns until it becomes one of Isaac (if it isn't already), then touch that doll.
- Black Eyes of Evil: Completely black eyes with no light reflecting off of it, as she's a Creepy Doll.
- Distaff Counterpart: She is effectively one to Lazarus, as both have playstyles that revolve heavily around them killing themselves repeatedly.
- The Many Deaths of You: This is her gimmick. By dying in different ways, she can generate specific rewards depending on how she died, once per floor. They are...
- Dying to a fire spawns 3 batteries and a Shop item.
- Dying to a laser spawns 3 cards and a Planetarium item.
- Dying to an explosion spawns 3 bombs and a Secret Room item.
- Dying to an enemy tear spawns 3 keys and a Boss Room item.
- Dying to Curse Room door spikes grants 3 Soul Hearts and a Curse Room item.
- Dying to paying your last heart for a Devil Deal grants you 3 black hearts and a Devil Room item.
- Dying to paying your last piece of health to a Blood Donation Machine grants you 3 Red Hearts and an Angel Room item.
- Dying to contact damage grants you 10 coins and a Treasure Room item.
Tainted Characters
Eika, the Stillborn
Eika depicted as a bloody fetus. She starts with Fetus Blood as a pocket active, which allows her to spawn unique Blood Bony's once per floor. She can only have red hearts but can still collect Soul, Evil, and Bone hearts to summon her own friendly Bonies, with the former two upgrade-able upon collecting more.
Her Birthright effect makes her Blood Bonys explode upon forcibly respawning from her Fetus Blood active.
Her Birthright effect makes her Blood Bonys explode upon forcibly respawning from her Fetus Blood active.
- Bloody Murder: Blood Bony's, summoned via Fetus Blood. who fight for Eika.
- Death of a Child: This incarnation of Eika takes her core concept, being a spirit of a miscarried child, and takes it to its logical conclusion by making her a bloody fetus.
- Dem Bones: Each of her summons are Bony's of differing abilities and characteristics.
- Undead Child: Even moreso than her regular counterpart. Here, she is effectively a Distaff Counterpart to ???, with her inability to gain any health other than red hearts being an inversion to ???'s inability to gain red hearts, and her physical appearance and monster-summoning powers also drawing parallels to Hush.
Satori, the Addicted
Satori... but she's in a wheelchair. Her wheelchair makes her start slow, but she gradually gains speed while moving. At high enough speed, she becomes hazardous to the foe, running them over or damaging them as long as her speed is not negated.
She also starts with a pocket active item called Transfuse, which deals half-a-heart of damage to temporarily increase her speed and damage stats, similarly to the IV Bag.
She also starts with a pocket active item called Transfuse, which deals half-a-heart of damage to temporarily increase her speed and damage stats, similarly to the IV Bag.
Her Birthright effect results in her charging attacks causing an explosion upon collision with an enemy at charging speeds.
- Car Fu: Her playstyle mainly revolves around building up enough speed to run over every enemy in her path.
- Handicapped Badass: Being in a wheelchair doesn't stop her from slaughtering any enemies in her path. If anything, it makes her more dangerous than if she decided to just use her tears exclusively.
Seija, the Bullied
Seija trapped in mediocrity. While she still has the same "Weak is Stronger, Strong is Weaker" gimmick like her non-tainted counterpart, all item pedestals now exclusively spawn items at quality level 2. Her pocket active D Siphon can either re-roll items to a lower or higher quality, depending on the number of rerolled item pedestals beforehand.
Her Birthright effect allows for her to better control the D Siphon's ability to raise or lower item qualities; reducing the quality by default, while increasing the quality by holding down the drop button while using it.
Her Birthright effect allows for her to better control the D Siphon's ability to raise or lower item qualities; reducing the quality by default, while increasing the quality by holding down the drop button while using it.
- Difficult, but Awesome: Because of the items' quality being set in stone whenever they spawn, she's stuck without any items that drastically affect her build, and the only way to get lower or higher quality items is through careful and efficient use of her pocket active. But because of said pocket active, she can effectively get any item quality with efficient use — the Balance Buffed quality 0 items which are obtained in two rolls, and the (generally) more valuable 3 or 4 qualities that are earned with sufficient siphoning. The latter qualities are still particularly risky due to Seija's gimmick, making it a toss-up to whether or not they'd be a worthwhile grab.
"Tainted Hourai"
Hourai, but half of her face is replaced with bloody flesh. This character is only accessible by touching the Hourai doll after attacking it to turn it into a Tainted Hourai doll.
Whereas Hourai's corruption revolves around her dying in many different ways, Tainted Hourai's revolves around her killing enemies in different ways, with a reward spawning with her on the next floor depending on how many ways she killed her enemies. Her Birthright makes non-boss enemies immune to damage from a triggered kill type when they take damage from a kill type that hasn't been triggered yet.
Whereas Hourai's corruption revolves around her dying in many different ways, Tainted Hourai's revolves around her killing enemies in different ways, with a reward spawning with her on the next floor depending on how many ways she killed her enemies. Her Birthright makes non-boss enemies immune to damage from a triggered kill type when they take damage from a kill type that hasn't been triggered yet.
- Difficult, but Awesome: While getting all 8 of the kill types triggered per floor is tricky, getting most of them nets you some powerful rewards. Getting at least 3 will net you a random item, 4 nets you an Ultra Secret Room item, 5 nets you a Devil Item, 6 and 7 increase the number of devil room items. And if you get all 8, You get a Death Certificate.
Bosses
Normal
The Abandoned
The cheery forgotten umbrella, Kogasa Tatara. Fought in Downpour.
- Invisibility Flicker: Only the Karakasa umbrella that she holds is seen normally, with the exception of her taking damage and fleeing the boss room, depicting her silhouette as a solid white light.
- Screw This, I'm Outta Here: Upon depleting her health, she briefly trips over herself, before grabbing her Umbrella and fleeing the area, but not before leaving the writing of "Boo!" in the corner of the room.
Necrospyder
Giant fungus-infected spider, based on Yamame Kurodani. Fought in Dross.
- Festering Fungus: The spider has mushrooms growing from the top of its head and one eye, with the implication that it is taken over by a Cordyceps-style fungus.
The Centipede
Rock-burrowing oomukade, based on Momoyo Himemushi. Fought in the Mines.
- Currency Cuisine: If there are pennies in the very room it's in (of which there will be when it spawns), it'll rush over to devour the money and restore any health lost, though thankfully it won't speed up like Ultra Greed does.
- Segmented Serpent: Each of The Centipede's segments have their own health bar, with it becoming shorter and shorter each time one of them is taken out.
Pyroplume
A phoenix, loosely based on Fujiwara no Mokou. Fought in the Ashpit.
- Auto-Revive: It has hilariously low HP for a boss, but makes up for that by resurrecting itself twice.
- Playing with Fire: It's a phoenix, so most of its attacks are fire-based.
The Summoner & The Immortal
A necromancer and their invulnerable mummy minion, based on Seiga Kaku and Yoshika Miyako, respectively. Fought in the Mausoleum.
- Invincible Minor Minion: The Immortal is completely immune to damage, and is only properly beaten by defeating the Summoner themselves.
Devilcrow
A birdlike machine with the power of nuclear fusion, based on Utusho Reiuji. Fought in Gehenna.
- Action Bomb: Upon having its health depleted, it'll unleash a massive, room-encompassing explosion that'll hurt Isaac if he doesn't take shelter behind the corner pillars.
- One-Hit Kill: Staying in the radiation beam for too long will kill Isaac, regardless of how much health he's got.
- Schmuck Bait: The radiation beam also covers what would be a glaringly large blind spot in Devilcrow's attack pattern, which may lead a new player who's unaware of the gimmick to hang out there (oh, look, a safe spot highlighted with a spotlight), oblivious to the significance of Isaac glowing green and rapidly beeping until he abruptly keels over.
Guppet
The remains of Isaac's pet turned into a marionette. Possibly based on Alice Margatroid and/or Medicine Melancholy. Fought in the Corpse.
- Punny Name: A mix of Guppy and Puppet, fitting for Isaac's pet turned into a puppet.
Secret Bosses (spoilers)
Doremy
Doremy Sweet, the Baku and ruler of the Dream World. Upon collecting the Dream Soul in the Ascent, she replaces Dogma and the Mother Beast as the True Final Boss.
- Battle Theme Music: The theme that plays for her boss battle is the stage theme for Legacy of Lunatic Kingdom, "A World of Nightmares Never Seen Before". Before the overhaul, she had her battle theme from the same game, "Eternal Spring Dream".
- Boss Rush: The revamped version of her boss fight can be best described as Mega Satan on crack. Her spell cards now incorporate attacks from nearly every other final boss in the game (which includes the likes of Mega Satan, Mother, and even Delirium). Hope you found a Wafer!
- Dream Weaver: Doremy, naturally as the Baku youkai, can manipulate dreams. In the secret boss fight, she appears to Isaac in his Dying Dream to avert his fate.
- True Final Boss: Doremy continues the Serial Escalation of this trope, this time being the Final-Exam Boss of all prior Final Bosses.
Reverie Music
A series of sentient music notes representing various Touhou characters. Upon meeting its requirementsnote , it effectively replaces Hush as the very difficult Superboss for the run.
- Battle Theme Music: Its theme song is "Illusionary Joururi
", shared with the Tsukumo sisters. - Item-Drop Mechanic: Each phase drops an item from a certain pool when the fight is completely donenote . Additionally, just like with Hush, a portal to The Void is guaranteed to spawn here alongide Sheol and Cathedral.
- Musical Assassin: Inverted, as its literal music notes that fight like their respective Touhou counterpart. Played Straight with the Prismriver Sisters' and Tsukumo Sisters' counterparts, who canonically fight with danmaku music notes.
- Mythology Gag: Marisa's counterpart exclusively uses two spells taken straight from Imperishable Night: Earthlight Ray, and of course, her signature Master Spark.
- Sequence Breaking: While you'd typically fight this instead of Hush, you can still teleport out of the room if you have the means to do so (0 - The Fool, Teleport!, etc.), not unlike with Mom. So if you can get back to Womb II's boss room within 30 minutes of the current runnote , it is entirely possible to fight both Reverie Music and Hush in the same run.
- Sequential Boss: It has five phases, each with their own health bars and unique Bullet Hell attack patterns.
