In Bleach, Komamura does this ("AIZEN!!") after Tousen's death.
Kenpachi does this after realizing he killed Unohana.
Incidentally, Ichigo actually has a non-tragic one after he defeats ByakuyaKuchiki. When a greatly-wounded and worn-out Byakuya walks away and concedes that Ichigo had finally won, and that he wouldn't hunt down Rukia for execution anymore, Ichigo looks up to the sky while the camera pans up away from him, as he let's out a primal, victorious scream to the heavens. Justified, considering how far he'd come and what he had achieved.
Several anime (Ranma ˝ springs to mind as an example) combine the Skyward Scream with some kind of reaction elsewhere, especially when the scream is either a curse (usually causing the subject to react, such as by sneezing) or a Battle Cry (in which case, someone may slip or accidentally break something).
Wolfram von Bielefeld in the Wham Episode of Kyou Kara Maou: his beloved king was last reported in this church which has since burnt down—but all anyone can find in the ruins is the lonely severed arm of the dedicated once-beloved brother he's been rejecting for years. Cue scream of frustration.
Also cue Character Development. Like anything. It's also after this that he reverts to referring to Conrad by name, which he apparently hasn't done since he was a little kid and found out niisan was half human.
Mermaid Melody Pichi Pichi Pitch blows the pants off this trope in the last episodes of the first season. LUCHIAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Done for comedic effect in episode 4 of Lupin III: The Woman Called Fujiko Mine, when Oscar comes across Zenigata unconscious and covered in blood. Lupin had just sprayed fake blood all over the Inspector, and Oscar had inadvertently knocked him out by coming out of the trapdoor just as Lupin escaped.
Aragorn, in The Two Towers. In a rare unscripted version, where Viggo Mortenson broke his foot on the helmet he kicked, eliciting a cry of real physical pain that fit the scene well enough that Peter Jackson kept it in.
For some reason, people think that Kirk screaming "KHAAAAAAN!" in Star Trek II was like this. It wasn't (it's a close-up of Kirk's face if you're wondering, cutting to a long shot of the moon he's on/in), but parodies of it do this. The misconception is prevalent enough that this trope was formerly namedThe Khan despite The "KHAAAAAAN!" not actually being an example.
The 2009 Star Trek movie has an actual example of this trope, though - Nero screaming "SPOOOOOOOOOOOCK!" during his Villainous Breakdown. This interrupts Nero beating the stuffing out of Alternate-Kirk, who sits up with a faint glimmer of recognition as Nero launches into it.
The "KHAAAAN" in the new movie is an example of it, however.
John Belushi's character screaming after the beer bar is taken away in Animal House.
Iconic movie example: In the film adaptation of A Streetcar Named Desire, just after realizing the error of his ways, Stanley Kowalski (Marlon Brando) screams out in the rain. The "STELLA! STELL-LLAAAAAAAAAAAAA!!!" is done with this camera angle and has become one of the most famous one-word lines in movie history.
Pirates of the Caribbean does this in the second movie, Dead Man's Chest: "Damn you, Jack... SSSPARRROOOWWWWW!!!!" complete with the pullaway camera angle from above (and Davy Jones spraying seawater).
Performed by Cindy (Anna Faris' character) at the end of every one of the Scary Movie series, although usually punctuated by her being run over.
Bartleby does this near the end of Dogma while laughing maniacally.
"WILLIAAAAAMMM!" William Thatcher also does this, screaming his own name, at the end of A Knight's Tale. Not quite skyward, though.
Parodied in the movie Charlie's Angels with Matt Leblanc howling "DAMN YOU, SALAZAAAR!" at the soaring camera while his girlfriend lies dead in his arms. And then we find out they're shooting a movie within the movie.
Don't forget that the scene takes place at the end of a montage showing the romantic B-plots of the other two angels, furthering the assumption that the girlfriend is Lucy Liu.
In X2: X-Men United Logan also does this in flashback following a shriek/roar of horror that is exactly how anyone would react to waking up in a tank of water with no memories and having metel claws shoot out of your hands.
In Harry Potter and the Deathly Hallows Part 2, Voldemort does this in his death scene. The effect of the rebounding death curse starts to disintegrate him, and he lets out a last, haunting scream as he turns to the sky and breaks up into nothing.
Ivan's reaction to his father's death in Iron Man 2.
A Nightmare on Elm Street 4: The Dream Master. After Kincaid witnesses Freddy's resurrection in the car graveyard dream, he tries to escape but is then cornered. He screams towards the sky, trying to signal his friends that Freddy is back, as the camera pans out to reveal that the graveyard covers the whole planet.
Seinfeld parodied this three times. The first time was George yelling "KHAAAAAAN!" after realizing his life must be dedicated to the Susan Ross foundation.note This is just after Jerry told how he had inspired Susan's parents to start the foundation with a line from The Wrath of Khan. The second time was Elaine yelling "SUUUUUUUUUUZIE!" after realizing her life must be dedicated to the Susie foundation, a fake character she initially made up to avoid troubles and later "killed" her to avoid exposure. The third time was George screaming "TWIIIIIIIIIX!!" after people ate up his candy lineup, which he set up to catch his candy's thief in a car dealership.
The Klingon death ritual first seen in Star Trek: The Next Generation invokes this, roaring into the sky to warn the afterlife that a Klingon warrior is on their way.
In the TV movie finale of Prison Break, T-Bag does this. "SCOOFIEEELD! SCOOOOOOOOOFIEEEEEEEEEEEEEEELD!"
Parodied in an episode of Whose Line Is It Anyway?? During a game of Weird Newswcasters (in which the comedians had to portray certain characters while being in a newscast), Ryan (the weatherman) was assigned a character of a self-centered actor about to give his "Oscar-worthy performance". Ryan finished off his bit with his character bellowing his last line as he looked up towards an overhead camera—while he spun instead of the camera. The audience burst out into applause at the end. View the whole game here (Ryan's performance starts at around 2:40)
Boy Meets World has Cory scream this way when he suffers from a very bad hairdo. Worse for him is the fact that he still has to go to school that day — without being permitted to wear a hat inside the school building.
In the classic "Dreams" episode of M*A*S*H, each main character's nap is disturbed by nightmares. Hawkeye's ends with him staring helplessly at a bleeding Korean girl, armless, as a patient-loaded helicopter flies low overhead, ending with a bloodcurdling No.
Done twice on Dexter, both involving the serial-killers-o'-the-season: in season three there's a "MIGUEEEEEELL!", complete with room-smashingalthough it was revealed he was just imagining how he'd like to react, and in season four, after the Trinity Killer evades his clutches once again, "ARRTHURRRR!"
Used in I Shouldn't Be Alive, to emphasize a stranded survivor's isolation as they yell for help and the camera zooms out to show they're alone in the midst of hostile terrain.
Smallville: Lex does one at the end of the episode "Persona" after his hired assassin informs him of successfully murdering Grant Gabriel, a clone that he created of his dead younger brother Julian, who turned his back on him for Lionel. This normally would have counted as his Moral Event Horizon, but because of the grief and regret that he showed by doing this, he was still considered at least a little sympathetic among most fans.
Merlin screams desperately for help from the Great Dragon when Arthur is dying in the Grand Finale.
Will: They will be AVEEEEEEEENNNNNGGGGGEEEEEEEDDDDDDD!
Gotham features one in the first few minutes of the pilot from a young Bruce Wayne after he and his parents are confronted by a mugger in a dark alley and...well, you know the rest.
The whole process is described in Razorblade Sigh by Gamma Ray.
Simple Plan's Untitled music video has the singer perform a skyward scream during, appropriately enough, the lyrics "I just wanna SCREEEEEEAAAAAAAAMMMM!"
Used by the Joker in Mortal Kombat vs. DC Universe's DC story mode after Captain Marvel tells Superman and the four DC villains the name of the Original GenerationBig Bad (Dark Kahn, a merger of DC's Darkseid and MK's Shao Kahn). Though the camera is above him, it cuts thrice, each one more distanced from him (and echoing his voice) rather than pulling away smoothly. Then Deathstroke tells him to shut up.
The first major turning point in Star Ocean 3 ends with Fayt screaming "WHAT THE HELL AM I!?!?!"
In Warcraft 3 in the scene when Grom Hellscream kills Mannoroth there are some pretty dramatic screams, that however being wordless don't quite qualify as Big Nos, and at the end of the scene, following Grom's death, a very powerful Khan Scream.
In Over Blood Raz shouts Pipo's name like this when he "dies" (he is a robot).
Kingdom Hearts II, when Roxas, upon discovering that all of his memories are fake, that he has no right to exist, and that to restore Sora's memories and wake him up, Roxas must be sacrificed. He attempts to attack DiZ for putting him through all of it, only to find out that he isn't even in the room, just showing him a projection of himself. Roxas's anger, despair, and frustration reaches a boiling point there, and he just screams. Poor kid has gone through some serious sh*t.
In TimeSplitters: Future Perfect, Sergeant Cortez lets out a furious 'Urgh... Gawd-DAAAAAAAMIIIIIIIIIIIIIIIIT!' after unwittingly giving the Big Bad the details of his plot. This takes place in the middle of the 21st century, but the skyward scream is so intense, it echoes through time, being heard by ally Harry Tipper in 1970, and a man implied to be Tipper's elderly son. Bonus points for the implication that Tipper is at the point of conceiving said son.
Asura's Wrath: Asura gets in on this one a few times, though it's actually rather rare that we see him doing so. His Skyward Scream for his wife is a single howl of rage and grief, though he does scream his daughter Mithra's name out as he goes to rescue her. However, when a human girl who looks like Mithra dies in front of him, he has a long moment where he seems like he can't breathe OR scream, and then the overhead view of the trope comes into play and very bad things happen to very bad people.
This was also used in his review of Saved by the Bell while recapping the oil drilling episode. When he announces the evil culprit behind Becky the duck's death, he dramatically looks up and proclaims "OIL!" complete with a spinning camera pull away shot.
In Homestar Ruiner, Strong Bad's response to finding Homestar is hiding at his house because of all the damage Strong Bad did to Homestar's reputation is to direct one of these at IIIIIIIRRRROOOOOONYYYYYYY!
Used in The Dr. Steel Show, Episode 1. As Doctor Steel checks his email, he becomes frustrated that his inbox is full of spam, and cries to the heavens (with accompanying jarring chord), "Damn thee, spam! DAMN THEEEEEE!"
(During his review of Pulse 3) The Internet ghost of a record player? THE INTERNET GHOST OF A RECORD PLAYER?! (To the sky with the camera spinning above him) THE INTERNET GHOST OF A RECORD PLAYER! IT MADE ME DO THE SPINNING SCREEN THING AGAIN!!!!
Also Nibbler in the Futurama film Bender's Big Score: "Doooomed!"
Bender himself has one in an episode wherein he takes a big breath and says "DOOOOOOOOOME-" before he's cut off by a scene change. His was the third in a series of the characters having progressively longer skyward screams.
"Ghost in the Machines" had Bender screaming "DAMN YOU, OBAMACARE!!!"
In the season 2 opening of Legion Of Superheroes, Imperiex does one of these. WITH SPINNING of course.
Parodied in The Simpsons with Rainier Wolfcastle's "MEN-DO-ZAAAA!"
Also done in "Bart's Comet", three times by Principal Skinner. The first is when Skinner gets back to Bart, only to find he's called the observatory with his find of a comet and they're gonna name it after him. The second is when Skinner accidentally lets go of the "Hi! I'm big butt Skinner!" weather balloon. The third is when Skinner read a disparaging remark about the Elementary school from a newspaper landing in front of him. Each one is accompanied by a Big "NO!".
Also, Homer's reaction to Mr. Burns failing to recognize him again in "Who Shot Mr. Burns, Part 1":
Homer: Kids, would you step out side for a second? (kids run out, Homer stands up, looks skyward) F— (cut to church organ hitting a minor chord) Flanders: Dear Lord, that's the loudest profanity I've ever heard!
And from the Movie we have "DOOOOOOOOOOOOOOOOOOOOOOOOMMMMMMMMEE!"
And from season 5's "Bart Gets an Elephant", whereupon Homer mistakenly believes Blackheart, the ivory dealer, took Bart along with Stampy:
Homer:He took Bart, too? (runs to window) That wasn't part of the deal, Blackheart! THAT WASN'T PAAAARRRRRRRT!
"DAMN YOU! A BOOOOOX!"
"Stroker and Hoop" parodied this with the character Stroker screaming "KHAAAAAN-ja" after being swindled and taken to a mental asylum by a woman, pretending to be an alien, (though later revealed to be a real alien) named Khan'Ja.
Demona from Gargoyles mixes this with a Big "NO!" when she discovers her planning got her own clan brutally killed, complete with her falling to her knees and raising her hands to the sky.
"THE BURDEN OF HOSPITALITY IS TOO GREAT FOR ROLF!!!"
My Little Pony: Friendship Is Magic: Spike does this twice (accompanied by a Big "NO!") in "A Dog and Pony Show", first when Rarity gets kidnapped by the Diamond Dogs, then again when he and Rarity's other friends end up lost in the Diamond Dogs' tunnels.
Pinkie Pie does this twice in "Games Ponies Play". The first time is just a massive overreaction to Twilight's pep talk, the second when the ponies realise they mistook a tourist for the Equestria Games inspector.
Coop from Megas XLR gives one of these (Retracting his robot car's convertible hood to do so) when he realized his battles with the alien robot of the week have destroyed the last Mega Slush machine in the greater Jersey area.
Arcee provides an incoherent one after Soundwave teleports her to the Arctic before she could reach an amnesic Optimus on the Decepticon ship.
Suprisingly, Optimus does this in "Inside Job" when Starscream steals the Omega keys. Dreadwing does it again in the following episode when he learns of what Starscream did to his brother's corpse and hearing Megatron's advice on keeping that secret from him.
Utonium: (Handed a note from school) P-P-PARENT TEACHER CONFERENCE?! NOOOOOOOOOOOOOOOOOOOOOOOOOOO!!!!!
Bubbles does this in "Mime For A Change" upon being the only person in Townsville who hasn't been drained of life and color by the evil Mr. Mime (just before she gets the idea to sing everyone back to color and life).