During his fantasy sequence about seeking medical attention for his fingers, the doctor flips open a steam-sterilizer and pulls out a cleaver:
Doctor: This is going to be extremely painful, Mr. Verrill!
During his "bummer" fantasy sequence about the broken meteor, the scene is framed with an overlay of a raincloud.
And at the end of the sequence, Jordy, utterly shamed, uses his hat to cover the worthless meteor.
Also the fact that the scene is set in the "Department of Meteors" at the university.
Or just the fact that his idea of getting rich off the meteor is being paid 200 dollars.
When he's about to bathe and strips down to see how much of the plant is on him, he screams in terror when he implies that the plant is growing over his crotch.
Jordy: Oh no NOT THERE!!!
Richard Grantham accidentally (on purpose) saying "hick" and not "husband" to describe Hank.
Henry's Indulgent Fantasy Segue where he fantasizes about shooting his bitchy wife right between the eyes, and everyone else applauds his aim.
Onlooker: Good shot!
Henry, as Billie is devoured by the yeti thing from the crate, simply tells her, "Tell him to call you 'Billie'!"
The garbage men who find the discarded comic at the end are rather amusing, particularly the note of disappointment in their voices that they can't send away for the "authentic voodoo doll".
Upson Pratt's conversation with Mrs. "Cat-sun-jammer", while showing that he's unbelievably heartless, is Black Comedy at its finest.
Pratt: Would you mind telling me who gave you my private number? I'd like to fire him.
Mrs. Castonmayer: (in tears) IT WAS IN MY HUSBAND'S ADDRESS BOOK YOU SON OF A BITCH!!
Pratt: ...well, I can't fire him, now, can I?
Richies insistence to his son he will quit drinking in "Gray Matter" is sad the first time, but the second time he does this, he pops open a can of beer almost immediately after. The third time, he is actually in the middle of drinking a beer, and his son just walks off in annoyance.
Apparently, Richies mutation into a Blob Monster caused him to, aside from gaining an insatiable hunger for human flesh, a sensitivity to light, and other such horrifying details, also made him addicted to daytime soaps.