"Yes, evil comes in many forms, whether it be a man-eating cow or Joseph Stalin, but you can't let the package hide the pudding! Evil is just plain bad! You don't cotton to it. You gotta smack it in the nose with the rolled-up newspaper of goodness! Bad dog! Bad dog!"
Amazonian Beauty/Statuesque Stunner - Jungle Janet of the Civic-Minded Five. On one occasion, a smitten Tick tries to woo Janet with a rose and... a potato that grew on his armpit... although to be fair, he was delirious from being doused with El Seeds growth formula.
There's also Belgian superheroine Eclair, a one-shot character from "The Tick vs. Europe." She is more androgynous-looking than Jungle Janet, though (for instance, compare her to her more traditionally feminine sidekick Blitzen), but this is never commented on by anyone and Die Fledermaus even hits on her (to no avail).
Anal Probing - Subverted. When The Tick is abducted by aliens, he is enthusiastic about being probed to expand interstellar knowledge, but it turns out the aliens actually want him to help defeat their enemies. The thought of probing him never crossed their minds.
Animal Themed Superbeing - The Tick... even if he doesn't actually suck blood. Also, Arthur is not a bunny, he's a moth (At least he could fly like one with his folding wings).
Not to mention Sewer Urchin, Die Fledermaus, The Ant, Man-Eating Cow, Bumbling Bee, Caped Cod, Portuguese Man-of-War, Cockroach, The Praying Mantis, Blowfish Avenger, Caped Chameleon, Captain Lemming, Fishboy, The Angry Red Herring, The Fin, Octo-Raymond, Shiela Eel, and more.
Ax Crazy - The Evil Midnight Bomber What Bombs at Midnight.
Badass Grandpa - The retired superheroes from "Grandpa Wore Tights," who despite their advanced age and failing powers, put up quite a fight against The Human Ton and Handy, and actually managed to defeat him.
This is averted in the Colombian Spanish dub, since they translated his name literally from German to Spanish and it's translated as La Rata Voladora (The Flying Rat).
Body Horror - "ARTHUR! My mustache is touching my brain!" Actually possible - a little bit of your brain actually does protrude into your sinuses (that's how you can smell). Also, The Tick's transformation in "Coach Fussel's Lament."
In the animated episode "Armless But Not Harmless," the Tick and Arthur are struck by a ray that causes their arms to fall off. The Tick takes his sudden debrachiation in stride. Arthur... not so much.
Tick: (clears throat) "All right... uh... this is quite a pickle. But no reason to panic, Arthur."
Arthur: (long, anguished scream)
Tick: (''spots a phone booth) "Ah... come along, Arthur! We'll call for assistance!"
Arthur: (screams again)
Not to mention the various, Dick Tracy esque villains, such as Zipperneck, who a zipper on his neck that he can pull down to expose the inside of his throat to horrify his opponents, Chairface Chippendale, Bolthead and countless others. Also worthy of mention is The Deadly Bulb/Pig-Leg, who for some unknown reason has a live pig in place of his right leg. The pig is perfectly healthy and acts like a normal pig, but being attached to eachother leads to some strife.
Bunny-Ears Lawyer - Arthur is pretty competent in a variety of things, once you look past he's in a giant moth suit all the time.
Averted in Arthur's backstory in multiple adaptations - he attempted to wear his moth suit all the time at his accounting position, and this bothered the higher-ups enough that he was "encouraged" to take a leave of absence and get psychiatric help.
The Tick himself qualifies, as well. When compared to most of the other "heroes" in The City, at least The Tick has the drive and focus to get the job done, most of the citys other heroes, with the exception of American Maid and, when it comes to sewer-related crimes, Sea Urchin, are either too weak, or too cowardly to be particularly effective.
Captain Ersatz - All over the place. The live action series had them for the major characters.
In Transformers Animated, of all places, The Tick gets one. Sentinel Prime is voiced by Townsend Coleman, resembles the Tick (he's large, blue and has a lantern jaw and antennae) and even speaks like the Tick at times. The biggest difference being that Sentinel is a Jerkass instead of a Cloudcuckoolander.
The City - Called, oddly enough, "The City." It's said to have been poorly Anglicized from the French "Les Citrons" (The Lemons). Apparently early French explorers found a large quantity of some kind of fruit in the area.
Clark Kenting - Clark Oppenheimer's glasses and The Tick's hypnotic tie.
Closer to Earth - American Maid, compared to Die Fliedermaus and most of the rest of the cast.
Continuity Nod - Countless examples, in addition to the Deface of the Moon example below. In one case, Handy loses one of his eyes at the end of "The Tick vs. Arthur's Bank Account" and when Handy returns in "Grandpa Wore Tights," he's wearing an eyepatch.
Conservation of Ninjutsu - In the comics. The third issue is titled appropriately "Night of a Million Zillion Ninjas" and they're every bit as ineffective as you'd expect with such large numbers. Justified in part by the revelation that Ninja has become a cheap franchise.
Later the Tick successfully blows up the C, but is blown off the moon before he can complete his job, leaving a "HA" on the moon. Later that episode, a Captain Ersatz of Galactus takes a bite out of the moon, which also remains.
Genius Ditz - The Tick may be very, very ditzy in just about everything, but he has shown a certain level of philosophical thought in some cases. Especially so in the second episode of the live-action series, where he learns that everyone (even potatoes) can die, and after thinking about it for about a minute, gives Arthur a motivating speech that actually makes sense.
Early-Bird Cameo - In one issue of the comic book, a mysterious female figure wearing a flying suit identical to Arthur's appears in a few panels. The comic ended before her story was revealed, but she later appeared in the animated series as Carmelita Vatos, daughter of the suit's inventor and (eventually) Arthur's love interest.
Evil Plan - Parodied in the pilot episode, when the heroes catch one of the Idea Men and demand he tells them his scheme:
Idea Man: "Well, we thought we'd steal a lot of money, and then we'd be rich, and we wouldn't have to work anymore!"
Tick: "You cads!"
Esperanto, The Universal Language - "Actually, Tick, I've taught myself to speak all your Earth languages. Except Esperanto. (chuckles) You could see that one was going nowhere."
Evil Old Folks - The Terror, a crazy old has-been supervillain who used to be buddies with Stalin. Back in the day he used to be a credible threat; these days, not so much, but he still gives Arthur and The Tick a good go of it.
Eye Scream - One of the retired old heroes from "Grandpa Wore Tights", The Visual Eye, had the power to eject his eyeballs from their sockets with the phrase "Rocket From The Socket", and fly them around for scouting purposes. In his old age, he can no longer control them as well, and when he sends them out, they simply flop to the floor, where the Human Ton ends up slipping on them like a pair of marbles.
Fantastic Voyage Plot - Without as much shrinking though. The just needed to get into Dinosaur Neal's body to remove the dinosaur DNA.
Feghoot - The episode "The Tick Loves Santa." Dear GOD, the episode "The Tick Loves Santa."
Felony Misdemeanor - The Dreaded Infinity Ball, the most powerful weapon of the Hey Empire. Lampshaded by The Tick: "We have things like those on earth. We knock them into little pockets with sticks."
God Guise - Of sorts, as other inmates of the Evanston Asylum that escaped when The Tick did start worshiping him, forming the Mystic Order of Arachnid Vigilance. Which then underwent Defictionalization as The Tick's fanclub.
Large Ham: Pretty much anytime that Tick opens his mouth. The scary part? His villains are often even bigger hams than he is! Done, as just about everything else in the franchise, as an Affectionate Parody of super hero comics.)
Limited Wardrobe - Tick and Arthur, and most of the other superheroes for that matter, are NEVER seen without their costumes, to the point where they usually sleep in them. In Tick's case, its debatable if it comes off at all. Arthur was seen without the bottom half of his suit in "Little Wooden Boy", after Swiss mercenaries stole his pants.
Mad Bomber - The Evil Midnight Bomber What Bombs At Midnight (yes, that is his full title). "Yeah, baby!"
Mad Scientist - The comic and cartoon being what it is, it has these guys coming out of its ears, but the most notable ones are the evil Dr. Chrome Dome, Brainchild and the mostly good but somewhat quirky Professor Vatos, the creator of Arthur's flying suit, as well as Dr Mung Mung, a less villainous take on the Yellow Peril, and the trouser-obsessed Dr Strangepants.
Magic Pants - Subverted and lampshaded in "The Tick vs. Dinosaur Neil," where Dinosaur Neil's monstrous transformation renders him completely nude, causing a group of top scientists outside of The City to attempt to clothe him with the largest pair of pants.
Well, they would. They carefully studied the situation, and came to the conclusion that the fact that he was pantsless was Neil's beef.
Paper-Thin Disguise - Often used by Tick and Arthur, who will usually just wear obvious disguises over their costumes, and in one episode, Der Fledermaus "disguises" himself by putting a rake over his head.
Pulling Themselves Together - The Living Doll is, as his catchphrase goes, "full of tinier men." Of course, that means that once the fighting's over he has to round himself up and make sure he's got all of them in the right order.
Spoof Aesop - "You know, though today was the worst day of my life, I learned many things. First, the world looks a lot different when you're six inches tall and covered with feathers. Second, two heads are definitely not better than one. And finally, you can lay eggs and still feel like a man."
Straw Nihilist - The Heys, an alien race that coincidentally happen to look exactly like Arthur, who have a species wide obsession with non-existence and the lack of purpose of life.
This Looks Like a Job for Aquaman - Sewer Urchin, normally somewhat useless and meek, becomes a Badass in the episode where they have to battle his sewer-based archnemesis. Here, he is largely unflappable with just the right tools for the job and a pretty cool base of operations.
Arthur: (sotto voce) "Who knew Sewer Urchin of all people would be this cool?"
Sewer Urchin: (revealing that he heard Arthur just fine) "Down here I'm the apotheosis of cool."
We Want Our Jerk Back - With the villains bringing him back. "We've got to rescue the Blue Tick, who is also mad, but in a much more goal-oriented way."
What Kind of Lame Power Is xxx, Anyway? - Many heroes and villains have weird/marginal abilities: The Indigestible Man, Pig Leg/The Deadly Bulb, Bi-Polar Bear, the Caped Chameleon, the Carpeted Man, Four-Legged Man, Baby Boomerangutan, loads more...
Apparently there was also a "Tommy Gun" that did something similar.
"The Tick vs. Europe" was this mixed in with Visual Pun and Bilingual Bonus. The Belgian superhero-sidekick duo of Eclair and Blitzen both have names referring to lightning (éclair is French for "(flash of) lightning", blitzen is derived from the Germanic word blitz), with Eclair actually being a lightning user. On top of this, an éclair is a French pastry (which is the first thing Tick thinks when he hears her name). Naturally, Eclair and Arthur have to take down a villain known as The Breadmaster.