Abandoned buildings are something we automatically learn to ignore, which makes them the perfect cover for someone who doesn't want to draw attention to themselves. Like certain less-than-legal businesses, or the Masquerade. Which means that that abandoned building off in the distance, might not be so abandoned after all, it's just kept looking that way to keep out the curious.
- The abandoned lot in the The Shadow turns out to be an entire hotel (the bad guy's base) disguised by illusion power.
- It's revealed in The World Is Not Enough that MI-6 has taken over a disused (and fictitious) Underground station under the Houses of Parliament, and from what appears to be a wrecked warship in Die Another Day.
- The burned and capsized wreck of the RMS Queen Elizabeth in Hong Kong harbour serves as a base in The Man with the Golden Gun.
- In Following, the burglar Cobb has a few hideouts in abandoned buildings where he stashes stolen goods before fencing them. He notes that London is full of spaces like these, waiting to be used.
- In A.I.: Artificial Intelligence, professor Hobby's headquarters and android production lines are located in the submerged ruins of Manhattan, for some reason.
- In Ant-Man, Scott tries to steal a MacGuffin from an old Stark Industries storage facility by taking an army of ants to break in. Only when they arrive do they realize that it's not quite as abandoned as Scott and Pym thought, as it's been turned into the Avengers Headquarters!
Scott: Hank, didn't you say this was "some old warehouse"? It's not! YOU SON OF A BITCH!
- In Harry Potter it is noted that, to the perspective of Muggles, Hogwarts looks like an abandoned castle.
- Academ's Fury has some of the students go into a decrepit school building... only to open a secret door and take a tunnel into their dojo, where they are learning to be Cursors.
- In John Sladek's satirical short story "Masterson and the Clerks" the eponymous characters work in what seems like a thriving office building, until a demolition company arrives to tear it down, claiming that it's been abandoned for years.
- Raylene from Cherie Priest's Chesire Red series is a cat burglar owns a seemingly abandoned warehouse to store things she's stolen. She lets two homeless siblings with prepaid phones to stay there and act as an alarm system, because while an actual security guard or electronic alarm system might look suspicious, homeless squatters in an abandoned warehouse doesn't seem out of the ordinary.
- In Robert Westall's The Machine Gunners, the gang of children build their secret fortress in the garden of a house that's been destroyed by a bomb blast and deliberately spread false rumours about seeing ghostly lights and other spooky things there to help keep people away. Later, they put up fake War Office signs warning of unexploded bombs and minefields.
- The dilapidated planetarium in the aptly-named online puzzle-story Planetarium is ignored by the townspeople and seems to be abandoned, and the story's narrator even points out that the mathemagician's purchase of it is a curious one, considering that he doesn't even visit it all that often. It, of course, turns out to have more than one surprise and living thing hiding in it.
- This car commercial. (In this case it's a car not a building, obviously.)
- Drug labs can sometimes involve abandoned buildings, especially those that produce a great deal of waste.
- And of course, there's plenty of cases where homeless people will be squatting in abandoned houses.
- Often perfectly good buildings are kept deliberately abandoned by their owners as an investment, hoping the prices to rise before selling or renting them out. Since this usually requires housing shortage to happen, the practice is often criticized, and regularly activists openly take over these buildings as publicity stunts to make public aware of this wasted space.