Examples with their own sections:
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Anime and Manga
- This situation is rare in voiceover because an actor supplying the voice wouldn't typically be "attached" to a project in the same way an on-camera actor would be, at least in a marketing sense, and a voice actor wouldn't really hurt their career by being in a flop. Nonetheless, there are a couple exceptions:
- Aya Hirano's career took a hit with the failure of Dragonaut: The Resonance and her own growing reputation as a "diva", forcing her managers to try to reel her in and limit her to supporting roles to save face. Hirano ultimately "left" the agency when she was caught in a scandal. However, it turned out to be a 10-Minute Retirement, and Hirano relaunched her career before the dust even settled.
- This might have happened to David Moo after he voiced Sanji in 4Kids Entertainment's infamous English dub of One Piece. His exaggerated and unfitting Brooklyn accent became the laughingstock of even non-fans of the series, and became something of a symbol of the dub's poorly done voice acting, strange treatment of the characters, or even 4Kids and bad dubbing in general. This is most likely to blame on the crazy voice direction causing even popular voice actors like Veronica Taylor to also turn in bad performances (Moo supposedly even disagreed with how he was asked to voice Sanji). He hasn't had any voice roles since, and was the only main voice actor not to return for Slayers Revolution and Slayers Evolution-R, where he had originally voiced Xellos. An interview with the Slayers voice director (Michael Sinterniklaas, who also took over the role) suggests that it was a decision made by the powers-that-be, and not a case of Moo leaving on his own. However, everyone else in the old One Piece dub still has at least some sort of career. The Love It or Hate It reception to his take on Xellos didn't help.
- Jessica Calvello's career was derailed for a long time (11 years to be exact) after what happened behind the scenes during the dubbing of Excel Saga. Because of the strain the character of Excel put on her voice, her contract with ADV Films required a 4-month break between volumes. When they didn't follow up on this, Jessica's voice was injured and ended up leaving the show (and was replaced with Larissa Wolcott). When she recovered, she moved to New York, where she found a decent amount of work, but nothing compared to the roles she had at ADV Films. She never appeared in another dub for ADV Films ever again (ADV shut down in 2009, 4 years before Jessica moved back to Texas), and didn't appear in another Texas based dub for well over a decade. Fortunately, she's getting a decent amount of work now that the Excel incident is long behind her, such as her roles as Saori Takebe from Girls und Panzer, Kanako Miyame in Maria†Holic, and Hange Zoe in Attack on Titan.
- Most of the Colombian Spanish dub actors and actresses who participated in the Kaleido Star dub were hit by this due to the negative reception of said in Latin America.
- When the Pretty Cure series bombed in Latin-America due to subpar dubbing and Executive Meddling, the budding career of Nagisa's VA Romina Marroquín-Payró almost took a nosedive. She managed to recover a while later when she took up roles like Princess Anna and Judy Hopps, however.
- Almost happened to Yukana Nogami when she played Four Murasame in the Zeta Gundam movies. First, Four's original seiyuu Saeko Shimazu wasn't cast despite still being active, so the fans immediately pegged Yukana as a Replacement Scrappy. Second, the director of the movie and one of the original seiyuu from the TV series were going through a scandalous divorce related to the guy's womanizing, and Yukana was apparently involved with him in the past. As a result Yukana was accused of pulling Casting Couch and took the brunt of the fandom's fury, which put her whole career in serious risk; it wouldn't recover until she was casted as C.C.
Live Action TV
- Prior to his namesake sitcom Emeril, Emeril Lagasse was riding high as one of the hottest TV chefs in the country. Then it tanked and he became just another face in the crowd. (It also has the misfortune of being Robert Urich's last series.)
- Michael Richards in The Michael Richards Show, the first post-Seinfeld project that established the "Seinfeld curse". Since it flopped in 2000, he's only done voice-over work (including in his old co-star's Bee Movie) and played himself in Curb Your Enthusiasm. His career was buried in 2006 by deciding to deal with a heckler at one of his stand-up comedy shows by screeching racial epithets at him. The incident was captured and uploaded to YouTube, ensuring that it would live on forever.
- The Paul Reiser Show promptly bombed as soon as it aired, and NBC cancelled it after two episodes. Considering he has done nothing noteworthy since Mad About You came to an end over a decade ago, this appeared to signal the end of Paul Reiser's on-screen career. However, he seems to have quietly regained some viability as a supporting actor in various movie projects, appearing in Behind the Candelabra, Whiplash, and Concussion. Additionally, a recurring role in the TV Show Married earned some critical acclaim for him particularly.
- Dick York's career ended with Bewitched. The show was highly successful, but his famous departure and replacement with Dick Sargent after six seasons due to a back injury resulted in him being out of the spotlight for a few years as he focused on recovery. When he attempted a comeback a decade later, he only booked one or two small things due to being out of the Hollywood loop for so long. He never acted again after that.
- Dick Sargent didn't have it much better. Nobody could see him in any role other than Darrin, and the only roles he could get were guest-star walk-ons on a handful of sitcoms. He mostly went back to stage acting after his on-camera career faded.
- Bob Denver could not follow the success of Gilligan's Island, and Dusty's Trail - an out-west carbon copy of Gilligan in which he played the title role - prevented him from making another prime time series thereafter. (He did find work on Saturday morning shows well into The '80s, with two animated versions of Gilligan's Island and Far Out Space Nuts.)
- Dan Fogler's attempt to jump into television after his film career died started with the ABC sitcom Man Up!, in which he served as co-star. Only eight episodes of the series were aired, and his TV pilot Prairie Dogs, produced the following year, did not go forward and was received negatively by those who saw it.
- Jay Mohr was billed as a rising star in the late '90s, playing memorable roles in movies such as Jerry Maguire and Picture Perfect, as well as having a recurring role on The Jeff Foxworthy Show. Action was meant to be his ultimate catalyst into fame, but it was panned by critics and burned out after one season (later Vindicated by Cable and has since become a Cult Classic). Since then, he's only managed supporting roles and TV shows that either were low-rated or short-lived.
- Rob Schneider of all people (known best for playing bit parts in Happy Madison movies and/or leading in ridiculous ripe-for-parody comedies ("Rob Schneider is: A Carrot!")) headlined a sitcom for CBS aptly titled Rob, where he played a milquetoast white guy married to a Spicy Latina stereotype (and both lived with her family.) It didn't last a full season and no one from the show, except for Eugenio Derbez, who would go on to star in the sleeper hit Instructions Not Included and is still iconic in his native Mexico, has been seen since. Schneider later dug himself deeper with 2016's animated bomb Norm of the North and his infamous Twitter tirades.
- Jeff Probst attempted to enter the daytime TV circuit with a self-titled talk show (his second attempt to move beyond the Survivor brand). To the surprise of almost no one, he actually suffered the same effect as Eliza Dushku experienced with Dollhouse. Wisely, he has continued doing only Survivor since then.
- ITV made headlines when it poached Ross Kemp from the BBC with a record 800,000 pound contract. They promptly shoehorned him into Ultimate Force, causing a significant retool, in order to justify the cost. The show performed incredibly badly and suffered nightmarish scheduling delays, resulting in Kemp's career as an actor effectively ending. He reinvented himself as an investigative journalist and has since regained significant critical acclaim.
- Sex And Drugs And Rock And Roll seems to have killed the career of Denis Leary, in addition to other shows he produced that didn't do well like Sirens and Benders. Since that show's cancellation, as well as Ice Age: Collision Course bombing at the box office, he doesn't have any projects slated for the future, when it comes to either acting or producing.
- Bette Midler in Bette, the spectacular failure of which effectively ended her entire acting career after For the Boys (see Film) crippled her film career. She now usually gets work performing her hits on various shows.
- Although Geena Davis was still stinging from Cutthroat Island, The Geena Davis Show didn't help matters. One telling clue: usually when a show is named after its star, they keep that name in the show - Emeril played "Emeril" in Emeril and Bette played "Bette" in Bette, for example - with Bill Cosby being among the more notable exceptions (The Bill Cosby Show, The Cosby Show, The Cosby Mysteries, Cosby and, of course, Fat Albert and the Cosby Kids - in none of those is his character called Bill). Despite being The GEENA DAVIS Show, Geena Davis's character was named "Teddie". Davis' career was then really thrown off the rails when Commander in Chief failed. It was supposed to be Davis' comeback and initially started strong, including an Emmy win for her, but ratings declined throughout the year before it was ultimately cancelled after 18 episodes. Davis has forged a new career focusing on researching women in film and bringing awareness to the plight of sexism within the entertainment industry, which has been met with critical acclaim. She still does acting roles here and there, the most recent of which is voicing the mother in the Studio Ghibli film When Marnie Was There.
- Lucille Ball, the star of I Love Lucy, conceived of the idea for, produced and acted in another primetime comedy series, Life With Lucy (no relation to Ball's Star-Making Role) on ABC in the 1980s. Given her past television successes through the 60s and 70s even after the end of her most famous show, Ball was given complete creative control over the series - which meant that she tried to replicate I Love Lucy's success in the 50's for an 80's crowd. Suffice to say, the attempt didn't work, and the resulting series (about a widow who goes to work at a hardware store) was painfully unfunny and cringe-inducing to watch (at least partially because Lucy was trying to duplicate her famous slapstick comedy, which didn't work nearly as well for her as it did when she was younger (pratfalls by a senior citizen make you want to call a doctor to check their hip, not laugh). The show flopped on arrival, and its failure made Ball stop working on any more projects (she died three years later).
- Wanda Sykes's once-strong career as a comedienne and actress fell apart after the failure of her talk show The Wanda Sykes Show. It was said that her openness about her lesbianism and her inability to appeal to Middle America blackballed her from ever heading a major production again. Her post-cancellation work has been mostly in smaller theatrical projects.
- Amber Heard had a lot of buzz about her movie career, reaching its height when she beat actresses like Scarlett Johansson and Keira Knightley for the role of Johnny Depp's Love Interest in The Rum Diary, which flopped at the box office. Then she starred in the dreadful flop TV show The Playboy Club, and her buzz was all but killed overnight. Heard's next few films like Paranoia and Three Days To Kill were critical and box office letdowns, and paired with her messy divorce from Depp, it seems most likely that her career won't reach new heights after that.
- Joan Rivers's career took a major hit in The '80s when she agreed to do a talk show for the then-new Fox network after it became clear she wasn't going to be tapped to replace Johnny Carson on The Tonight Show despite being its regular guest host by then. Carson refused to speak to her after she did this, and after she was fired from The Late Show she was blacklisted from Hollywood for years.
- Nikki Cox became an instant sex symbol in her role as the teenage daughter, Tiffany Malloy on The WB sitcom (one of the network's earliest shows back in early 1995) Unhappily Ever After. When Unhappily ended its run after 100 episodes in 1999, Cox starred in her own sitcom for the WB called Nikki, which lasted for two years. However, sometime after leaving the NBC series Las Vegas, Cox reemerged (after having had some ill-advised plastic surgery) in a guest appearance on the CBS series Ghost Whisperer alongside her real-life husband Jay Mohr (a former SNL cast member from season 19 to season 20. While his screentime was very limited and he ended up getting screwed out of being a member of the season 21 cast, Mohr is remembered for his impression of frequent host Christopher Walken). Since that time, Cox's most notable acting role has been voicing Silver Sable on The Spectacular Spider-Man.
- Pink Lady's popularity in Japan had peaked in 1978, and by 1980 they had been rocked by a few scandals that had pushed their Japanese record sales into decline. So they shifted their focus to the United States, and ultimately gambled on Pink Lady and Jeff reviving their careers. Except it didn't work out, and they disbanded a year later.
- The short-run of FOX sitcom Stacked marked the end (as Chris "Rowdy C" Moore further explained in his TV Trash review) of Pamela Anderson's career as a television star.
- The failure of the 2011 remake of Charlie's Angels seems to have ended Minka Kelly's career as a leading lady, as her career has mostly been quiet since (outside of a small role in The Butler).
- Eliza Dushku hasn't had any prominent live-action TV roles after Dollhouse, after many reviewers expressed the opinion that a role intended to display her versatility, and ability to play something other than a sexy, morally-ambiguous action hero, actually had the reverse effect. Most of what she's done since has been voice acting in parts that reflect her standard Type Casting and appeal to her established geek fanbase.
- Perennial geek culture fan-favorite Summer Glau seems to have finally been done in by the cancellation of The Cape, making it her third cancelled series in six years (fourth, if you count Dollhouse, in which she has a somewhat small but significant recurring guest starring role).
- While Charmed itself was a significant hit, the derailing came from Shannen Doherty's high-profile exit after the third season. Having been a respectable TV star in the '80s and '90s, she was notably dismissed from Beverly Hills 90210 at the end of the fourth season due to tension between her and other cast members. Similar stories surfaced on the Charmed set, with T. W. King leaving after Season 1 — rumoured to be because Doherty didn't like him (though other sources say he asked for more screentime and was just cut). Doherty herself left the show very publicly after a feud with co-star Alyssa Milano, to the point where she allegedly said "either she goes or I do". The fact that she had been fired from a second hit show after fighting with cast members earned her a reputation as a diva, as did her subsequent refusal to allow Charmed to use any archive footage or pictures of her — which meant that it took until 2005 for the first three seasons to come out on DVD. She turned to Reality TV projects and TV movies, but never with the high profile she once enjoyed.