Kingdom O' Magic is a point-n-click fantasy adventure game almost entirely dedicated to sending up Middle-Earth, with just about every named character and location a punned-up version of something from the pages of Tolkien's novels.
BoxxyQuest: The Gathering Storm spoofs the hell out of every aspect of “internet culture” it can think of, and then some. It also has a great time playing with JRPG tropes, usually ones that don’t often get targeted by these types of games.
While Spooky's Jump Scare Mansion is genuinely horrifying, the actions of the titular Spooky and some of the notes lead to Black Comedy. That, and the game playfully jabs at many common tropes found in horror games.
The survival horror game, Camp Sunshine, is this to 80's Horror, with emphasis on the "Affectionate" part. The game is genuine horror, rather than an out-and-out parody, but in the vein of some of the later horror films of the 80's, the game is willing to get a bit campy at times.
Barkley, Shut Up and Jam: Gaiden is a fully playable 16-bit JRPG-like game that parodies the genre. The game is quite a bit less affectionate with its parody of the RPG Maker community and certain Internet subcultures in general—two of the "truck pump" rants that you read before saving are taken verbatim from real internet discussion forums, although one was a reaction to one of the made-up rants that the author confused with the real thing.
The RTSMajesty puts the player in charge of a fantasy kingdom that works the way they do in RPGs with a setting that puts every Swords and Sorcery trope in a blender and makes a smoothie of it. As such the city guards are helpless against anything bigger than the giant rats infesting the sewers, and the sovereign has to summon heroes (who are not directly controllable units) and post rewards for things like the ancient evil castles littering the landscape in order to get anything done. The heroes on offer include stalwart warriors with names like Sir Baramer Broadedge, kooky nature cultists, conniving rogues, Workaholic dwarves, and white-bearded wizards who are as fearsome as they are clueless.
Viewtiful Joe affectionately parodies the plots, characters, and settings of Tokusatsu and Comic Book heroes in general, with the gameplay being a highly enjoyable twist on 2D beat-em-ups. So does The Wonderful 101 from the same dev team, only it's a 3D beat-em-up.
The Wii game MadWorld, a spiritual successor to God Hand, continues its ancestor's stint of parody by turning the focus from Japanese entertainment (video games and anime) to western entertainment (gory, violent video games, reality television and graphic novels), sending up their violent tendencies in a comedic, Tom and JerryItchy and Scratchy kind of way.
Anarchy Reigns: Though seemingly very strait-laced in terms of story, but characters are definitely parodies. You have 3 assassin chicks and the only serious one is RinRin, the other two are very... odd, one being a gambling and self-absorbed chick obsessed with her beauty, the other is a hyperactive girl who makes Funny Bruce Lee Noises and breaks her gaming system for losing. The main characters of the story are much more serious, but side characters are clear parodies, sometimes of the expected type of character to be in a fighting game.
Apollo Justice: Ace Attorney takes the opportunity of a new main character to occasionally parody the very series that it belongs to. Apollo gets reprimanded for shouting the series catchphrase in court and often laments the fact that he never gets any normal clients, Trucy advises him that "Daddy had days where everything would go wrong too" and Phoenix reminisces on his days of using the Present command and flashing his Attorney's Badge to everyone.
The Tex Murphy games: Every plot element from old-school, black and white, noir private eye films are lovingly re-created and mocked.
The Leisure Suit Larry games started out as classic parodies of the text-adventure games their own company was famous for, most particularly their less-than-family-friendly Softporn Adventure. Lowe pretty much took the whole thing and did a Tone Shift, playing it all for raunchy laughs.
Likewise, many of the Sierra "Quest" games (King's Quest, Space Quest) spoofed fairy tale or sci-fi tropes. It was a bit more tongue in cheek in King's Quest, but Space Quest was nothing but rapid-fire sci-fi jokes.
Konami also parodied its own Castlevania series from the 8- and 16-bit era with the Kid Dracula series. Kid Dracula himself appears as a character in one of the Parodius games.
After Parodius, other companies made silly versions of their most famous Shoot 'Em Up series. For instance, Taito mocked Space Invaders with Akkanvader (AKA "Space Invaders: Attack of the Lunar Loonies"), Namco spoofed Galaga with the Cosmo Gang arcade game and Hudson Soft made fun of the Star Soldier series of games with Star Parodier.
Mesal Gear Solid was an extended parody of Metal Gear Solid, which would have been better if a parody of Metal Gear wasn't just the same thing but with a "laugh track". Still, there's a twisted beauty in watching a husky-voiced little monkey croak out a monologue about how the use of mines in combat is a humanitarian disgrace.
In a similar vein, Metal Wolf Chaos is FromSoftware cheerily mocking the everything-to-eleven spirit of mecha anime, flag-waving American patriotism and their own Armored Core series. They clearly love all of these things.
The Disgaea series frequently parodies anime and its cliches. Captain Gordon, Defender of Earth! is a parody himself.
Raspberyl: (in response to a parody of A Dog of Flanders, and the latest in a chain of parodies) Are we even allowed to parody that? Sapphire: I don't think so...
And anime series featuring toys as their main selling point, like Beyblade.
As well as a few jokes at Square Enix's (the game's producer) expense, such as the character designer'sobsession with zippers ("Then I wish I had more zippers, so I could tell you to zip it!") to your common emo RPG protagonist ("Must...resist...emo...urges..."), and even a joke about yaoi fangirls (which create a significant fraction of Square Enix fanfiction).
Serious Sam is not-at-all serious, but a self-conscious send-up of FPS games that spread itself across other action game and film sources, and parodied Duke Nukem with particular affection.
The Merry Gear Solid games, particularly Merry Gear Solid 2. They're really scathing and attack with pinpoint precision all of the silliest things about an admittedly pretty silly series, like the ridiculously convoluted plots and turgid infodumps, but the sheer dedication to getting everyone in-character and replicating the Original Flavor of the Metal Gear series is what's most noticeable. The games even take stabs at morals and postmodernist fourth-wall wankery. As well as Christmas-themed Hurricanes of Puns.
Metal Gear Solid 3: Snake Eater, in typical Metal Gear fashion, is both a parody and a homage to James Bond movies. The game even starts with a typical Bond opening scene which ends in a climactic explosion that turns into the extremely bond-like intro movie. Then the actual mission of the game begins back in America where Bond Snake receives his briefing. Back behind enemy lines he makes contact with a Soviet double agent who turns out to be the game's Bond Girl.
It also takes a lot of jabs at its near-future rival Splinter Cell, particularly the obsession with futuristic gadgets.
One Night at Flumpty's is clearly a parody of the Five Nights at Freddy's franchise, replacing the creepy animatronic images the player sees on camera with humorous or casual images of the enemies. The Jump Scare deaths still play a big role in the game though.
The Grox from Spore are a spoof pastiche of the Borg from Star Trek: The Next Generation (with their cyborg limbs) and the Daleks from Doctor Who (with their war cry being "EXTERMINATE! EXTERMINATE!"). However, some of their threats are less then effective. ("You will not get a holiday card this year.")
Fur Fighters last hub is just one big homage to James Bond, with secret volcanoes bases, stock-piles of gold, a duo female fighter force consisting of a deer and a rabbit and a small little bald man... being petted by a large white cat.
Indie game Indistruc2Tank's story mode is a massive parody of Metal Gear Solid, but there's a little too much genuine heart in there ("Give me...a soldier's death!") for it to be a proper skewering.
Sonic Colors is an affectionate self-parody of the Sonic series, making fun of Eggman's robotic skills, Sonic and Tails' approaches to being a hero, and 3D Sonic in general. In doing this, is it is a fairly pointed, but affectionate, Deconstruction.
Duke Nukem 3D is an affectionate parody of Doom, combining the latter's over-the-top violence with Black Humour such as turning the LAPD (or LARD as they are in the game) into literal pigs.
Brütal Legend both celebrates and parodies stereotypes associated with Heavy Metal music. It was made by veteran video game designer Tim Schafer, who has been a fan of heavy metal since he was a teenager.
It's only for a moment, but Ratchet & Clank: Going Commando affectionately mocked the power cell videos in the first Jak and Daxter by having Clank do Daxter-style dancing... while Ratchet looks on with a worried expression.
The Flash game Pretentious Game (which can be played here) gently pokes fun at the conventions of pretentious puzzle-platform games like Braid and Limbo (and the many imitations they spawned) while at the same time being a pretty good example of the genre, using gentle music and minimalist game-play and graphics to tell a story of unrequited love.
Double Dragon Neon is not so much a love song as it is a power ballad to beat 'em ups, the Double Dragon franchise, and the 1980's all in one awesome package.
The Neverhood parodies the Creation story in The Bible. Given that Doug TenNapel is himself a Christian, the "affectionate" part is easily understandable.
There's a tale in the Bible about a man named Joseph who saved his reputation by being able to interpret dreams; one character (Klee) mentioned in the Hall of Records does the same by reading portents in people's bedhead.
There’s also a reference to the tactic Joshua/Jesus Nave used to conquer Ai.
Let's just say that a great deal of the Hall of Records is a Shout-Out to one Bible story or another.
they turned trembling to one another, saying "What's up with that?"
Resident Evil 4 manages to parody its own series. The Resident Evil series serves as one of the cornerstones of survival horror, but the fanbase regularly makes fun of many of its quirks and flaws. The developers of 4 tried their best to embrace as many of Resident Evil's more memetic issues, including its comically atrocious writing and voice acting as well as the utter absurdity of the game's premise itself. Previous games were known for their Narm caused by their complete seriousness in the face of glaring literary flaws, but with 4 the developers deliberately went for the Narm Charm route and ended up producing an enjoyable game that didn't hesitate to poke fun at itself and its history. For instance, while the "master of unlocking" line was unintentionally funny in a cringingly bad sort of way, the "Your right hand comes off?" line can't help but be deliberate in its corny hilarity.
Team Fortress 2 is an Affectionate Parody of FPSes in general. The objective of the land war is seemingly completely pointless, the setting is gleefully demented, and each of the nine classes are Player Archetypes painted with a very broad brush and ten coats of crazy.
DragonFable is packed with these. A random example would be the quest boss "Puce Person Eater", which, you guessed it, is one-eyed, two-horned and purple. The item description follows the lyrics almost to the word.
Call of Juarez: Gunslinger is home to almost every single Spaghetti Western trope in existence: the Gunslinger who wields two guns, the Roaring Rampage of Revenge, the Showdown at High Noon, Violent Prison Escapes, bounty hunters, famous outlaws, Indians, an Unreliable Narrator framing the whole work in the guise of a story told over drinks... and yet while laying out all these tropes shamelessly for us to see, it still clearly embraces them all with joy, shown in its sincere and involved presentation of the story and characters, and the earnest interest of in-universe fanboy Dwight, who almost comes across as the surrogate voice for the devs themselves.
Syobon Action is an affectionate parody of both Super Mario Bros. and stupidly difficultplatformers, while also being an excellent example of a stupidly difficult platformer itself. Part of the fun is finding out just how creative the devs got in their attempt to make the game absurdly hard, so you will encounter several traps that are so ridiculous and unexpected you have to laugh.
Brazilian game Songs for a Hero is one towards Sonic and Mario-like platform games, with the protagonist frequently pointing out and questioning in song form oddities and conventions from the genre, such as floating platforms, Solid Clouds, NPCs repeating the same phrases and his enemies dropping coins after being slain, all while being a passionate game of the genre on itself as well.
The Matrix: Path of Neo; The first training level seems to be this to Mortal Kombat what with Neo wearing a black tunic with a crest pinned on his chest, a red band wrapped around his head, and 'bandages' or something wrapped around his waist and fists. Further this, is the three round 'tournament' at the end of the level; the screen suddenly flashes "Round 1", "Round 2" and "Round 3" in ragged, bright, red, yellow and orange letters, all while Tank announces "Fight!" at the start.
Mind Your Manors is a cartoony, Gender Bender themed parody of horror games, taking place in a haunted house from which the protagonist must escape while avoiding the ghosts within.
The Teen Titans Go! game Teeny Titans is one to both the monster-fighting and toys-to-life genres, particularly the latter instilling a primal desire in its consumer base.
Ninja Pizza Girl: In a futuristic, rain-soaked urban sprawl, a sinister megacorporation sends its ninja operatives to crush the plucky street-level entrepreneurs threatening to disrupt its complete monopoly on... pizza delivery. One might notice a certain tongue-in-cheek resemblance to another game about rooftop-hoppingCyberpunk heroes fighting The Man by delivering stuff. At the same time, Gemma's family's efforts to keep their small business afloat in the face of corporate competition is treated with great seriousness and pathos, and the gritty, industrial environment with its diverse, quirky inhabitants is lovingly crafted. And let's face it, jumping between rooftops is just plain fun!
The fifth crossover between THE iDOLM@STER: Cinderella Girls and Granblue Fantasy is a parody of Resident Evil, being titled "Piña Hazard" as people are being piñafied into what are basically zombies. Its preview even had its own version of the infamous Keeper's Diary ("Itchy itchy skyfarer came... Mm, hungry and eat piña food...").
Wingman DX is an Affectionate Parody of the dating simulator genre, deconstructing both the mechanics of visual novels as well as many of the narrative tropes in dating sims and romantic comedies. Perhaps the most obvious example is it's a game about dating sentient hot wings.
The Fan-Game Grand Dad Mania pays homage to various bootleg hack roms and unlicensed games.
Where Hitman games are on this spectrum varies with each installment. You can read 47 as a cold, mysterious man in black who assassinates rich and famous members of global conspiracies. Or you can make him wear a flamingo mascot suit and throw books at people. Your choice, really.
Guacamelee! is this to Mexican culture as a whole. Sure, everything might look all stereotypical at first, but look closer and you can see that they really did some background research on the whole thing. All in all, the game is just as much a celebration of Mexican culture as it is a parody of it.
Zombie Vikings' story and scenery heavily draws upon Norse mythology, and lovingly mocks heroic god-given quests in general.
Evil Zone lovingly parodies 90s anime tropes, with each character representing a different genre and receiving a story mode in the style of it.
Doki Doki Literature Club! starts out by parodying Visual Novels, Romance Games and Japanese stuff by playing all the tropes straight in all their silliness, since people who already know the genres tend to make fun of them anyway, and people who don't are probably going to find it weird or even absurd, like with the Finger-Suck Healing scene. This only lasts until near the end of Act 1, though, when the normal tropes stop working and things really start to get interesting...
World of Warcraft: A very subtle instance; the game is parodying its own players. In the Borean Tundra zone, there are enemy NPCs who work for the Great White Hunter, Hemet Nesingwary. Upon engaging combat with a player, these enemies will yell out things like "Just fifty more hooves and I'll have the new gun!" Replace all the nouns with more appropriate ones, and how often have you heard that said before? Or even said it yourself? Not to mention there are multitudes of slight knocks on the tropes of fantasy, sci-fi, video games, and pop culture in general throughout the game, always affectionate, of course. Keep clicking on an NPC, hilarity will ensue. Also, post-Cataclysm Hillsbrad has you act as a quest giver interacting with NPCs who act in exaggerated stereotypes of the clueless new player, the arrogant high-level player who ganks low-level players, and the obnoxious low-level alt.