Critical Research Failure: A rare one for Randall, but it still happened. A question on how much power can be produced by The Force compares Yoda's power output to that of a Smart Car, with Yoda popping out of the front hood of said car. However, the Smart Car is a rear-engine car, with the front flap covering various auxiliary components.
Similarly, the parody issue (vol.1 #34) had a short story asking "What if Iron Man had an eating problem instead of a drinking problem?", showing Tony Stark becoming morbidly obese from over-indulging on fast food. According to Robert Downey Jr., he realized he'd hit rock bottom one night when he was scarfing down tons of fast food burgers, which lead to his quitting drugs and cleaning up his life...which, in turn, led to his being cast as Iron Man.
Hilarious in Hindsight: Plenty of scenarios in the comic actually happened as time went on - Spider-Man joined the Fantastic Four in the Hickman run, Hulk became a barbarian in the Planet Hulk series, Comic-Book Time means that Captain America was probably revived decades after both iterations of "What if Cap were revived today?", Elektra's survival has been retconned in...
The joke scenario in #34, "What if Every Avenger Remained an Avenger", depicts the silliness of an Avengers team with around twenty-six members. Ever since Civil War, that lineup has looked downright sparse.
Even more so, since Vol 3 has an early issue beginning with thirty-odd Avengers trying to stop Whirlwind robbing a bank, and tripping over one another.
In "What if J. Jonah Jameson adopted Spider-Man?" (v2 #82), Flash Thompson becomes the Scorpion. Years later in canon, he'd claim another power set that once belonged to Mac Gargan: Venom.
#46 of the second series, "What If Cable Destroyed the X-Men?", leans toward Harsher in Hindsight. The book opens with Cable killing Professor Xavier, Jean Grey, and Cyclops. This was released just a little less than a year before it was revealed that Cyclops was Cable's father.
The world shown in "What If Charles Xavier Had Become the Juggernaut" is effectively House of M, albeit with Xavier in charge instead of Magneto, a mutant-dominated world where humans are second-class citizens.