Creator Killer: Though a commercial success, it's poor critical reception and international box office caused a major shakeup in Disney staff.
Director Mark Dindal, who's career was already not doing well after Cats Don't Dance a decade prior, was not credited in another movie until 2019's Wonder Park. All of the projects he was involved with in-between died in Development Hell.
It was the final blow to Michael Eisner's time at Disney. Following a decade of failed investments in Disney Theme Parks, plus internal struggles with both Roy E. Disney and Pixar's John Lasseter, Eisner resigned shortly before the film's release, passing the torch to Bob Iger. He's has since stuck to producing TV shows through The Tornante Company (including critical darling Bojack Horseman), though his creative input has been minimal after the failure of Glenn Martin DDS, which he co-created.
Eisner's depature also resulted in animation head David Stainton being replaced by Ed Catmull.
Executive Meddling: The movie originally stuck to the fable by using a female Chicken Little and you can even see the original opening with the female Chicken Little on the DVD special features. Michael Eisner had her changed to a boy to appeal better to young boys.
Follow the Leader: It's no secret that the film's snarky, edgy humor is trying to capitalize on the success of Shrek (though in this case, it's less anti-Disney humor and more self-deprecation).
Star-Derailing Role: Garry Marshall, who's character was seen as one of the major weak links in the film, had exactly one more starring role in a feature film with Keeping Up With The Steins, released a year later. Outside of a few cameos or bit role on TV, he didn't do much acting afterwards and largely stuck to writing and directing for the rest of his life.
Stillborn Franchise: A Direct-to-Video sequel, simply titled Chicken Little 2, was planned. In it, Chicken Little's his childhood sweetheart Abby Mallard would find herself in a Love Triangle with him and Raffaela, a French sheep, inspiring her to get a makeover. The film's poor critical reception and the management shakeup at Disney Animation a year later cracked this egg before it could cook.
"Take That!" Tit-for-Tat: Michael Eisner was not thrilled about his former colleague and now rival Jeffery Katzenberg using a caricature of him as the villain in the computer-animated hit movie Shrek, and wanted to beat him at his own game by doing his own CGI movie full of snarky-self aware humor. Needless to say, it wasn't much of a fight.
The first draft of the film stuck closer to the original fairy tale. It was to be set at a sleepaway camp, Chicken Little was◊a◊ girl◊ and the main villain was "Wolf-in-Sheep's-Clothing." After Michael Eisner had the main character changed to a boy, the entire story was overhauled into a space-invaders story.