Many old Hanna-Barbera characters have Meaningful Names. Mr. Jinks (homonym of "jinx") is periodically shown to have bad luck. You know Scooby-Doo's cousin Scooby-Dum isn't going to be the sharpest knife in the drawer. And guess what color Grape Ape is?
Bender (whose full name is "Bender Bending Rodríguez", by the way) is a "bending unit" — a robot who was manufactured for the sole purpose of bending metal objects. Also, one slang meaning of "bender" is "a bout of heavy drinking", which is appropriate for Bender since he runs on alcohol. His name also brings to mind John Bender from The Breakfast Club, a famous rebellious asshole. The other meaning (homosexual man, UK slang) is not quite as appropriate, unless the writers are trying to hint at something.
The same can be said for Flexo and his ex-wife Anglina, who are also bending units.
Leela's full name - Turanga Leela - is a reference to the "Turangalila-Symphonie", a piece of music most famous for prominently featuring the ondes Martenot, forerunner of the classc sci-fi staple the theremin. Also, in the case of purple-haired Leela, "Lila" means "purple" in German.
In Futurama's famously esoteric style of humor, "Farnsworth" was the name of the man who built the first television system.
Morgan Proctor is a bureaucrat. Her name is triply appropriate, the first being the most obvious, though the others work if you stretch it note if you can't figure out why, think "proctologist": She's a bureaucrat, so she's anal, and she's also something of an ass.
In "Fear of a Bot Panet", a planet inhabited by robots was named "Chapek 9" as a reference to Karel Capek's coining of the term "robot".
The kids involved in the re-enactment of the Sith-il War provide us with these gems: Darth Stroyer, Darth Trocious, Darth Urderer and Darth Sploder. note Poking fun at a somewhat milder meaningful naming scheme in the Star Wars franchise.
Long, even though it's the last name of Jake's Caucasian father, is one of the Chinese words for dragon.
Rose, the love interest/misguided bad-guy protege, is a beautiful thing with thorns (Thorn was her Secret Identity's original name). (It's such a common name for a Femme Fatale, Disney had to change her alias or risk copyright infringement for there was already a DC character with the same names.)
Jake's grandfather and mentor is named Lao Shi, Chinese for "respected teacher".
Mr. Wuncler: the archetypical scheming old white businessman. His name is pronounced just like "The Once'ler", the narrator and misguided, remorseful villain of Dr. Seuss' The Lorax, who destroys essentially the whole world to make a quick buck.
The main character Huey Freeman is named after Black Panthers co-founder Huey P. Newton. His surname, Freeman, is also significant as it means "a free man".
Ed Wuncler's pal, Gin Rummy, is a thinly veiled "gangsta" analogue of former U.S. Defense Secretary Donald Rumsfeld (who even quotes Rumsfeld's "known unknowns" speech after a botched convenience store robbery).
Aaron McGruder loses a thousand subtlety points for naming the successful, well-off black man Tom Dubois. As in "Uncle". And W.E.B. Dubois.
Transformers are almost always named this way, either by their abilities, or their alternate form. Often, if a transformer undergoes a major change in their body (such as a new alternate form), they'll even change their names to match it. A Transformer gets a codename (generally of the Descriptive type) as a real name.
Brawn, for example, is a rough-and-ready brawler who believes in might over microchips.
Skywarp has the ability to teleport. And push people down stairs, according to TFWiki.net.
Other examples include Rattrap, Infernoexplanation either the fire-fighting Autobot, or the Predacon fire ant obsessed with burning things, Sky-Byteexplanation a flying shark, and Evac, to name just a small few.
Transformers Animated has the human villain Prometheus Black, A.K.A. Meltdown, who got his powers from an accident after stealing some of Bumblebee's hydraulic fluid. The parallels to the titan Prometheus should be obvious — especially if you know of the versions in which Prometheus was an arrogant upstart who stole the Divine Fire without knowing what he was meddling with, rather than being in the right, with Zeus just being afraid of progress. The other human villains all fall under the Steven Ulysses Perhero subset.
What's interesting is, the speedster Nino Sexton overhears someone saying he came through in a nanosecond, so he calls himself Nanosec. His codename's resemblance to his real name is, in-story, pure coincidence, and the other human villains may well be the same. Slow-Mo, on the other hand, is said to be named for the Hasbro executive Samantha Lomow.
There are times that the character is introduced and named... in the story that gives him whatever it is he's named for. So Crosshairs, Pointblank, Slugslinger, Triggerhappy, and Sureshot were given these names at some point long before we met them, unrelated to their jobs or whatever it is they turn into, and their weaponry is nothing special. Then, by pure coincidence, these particular bots wind up in the events that make the Targetmasters (that is, human-sized Nebulan aliens in mobile suits turn into guns for them and act as gunners.) Meanwhile, four Autobots have lived all their lives with names such as Chromedome, Hardhead, Brainstorm, and Cerebros and by coincidence become Headmasters (same idea, only with heads.) Having head-related names beforehand makes no sense either - most characters tend to have heads, and theirs don't do anything others' don't pre-Nebulos. At least the Decepticon Headmasters' head names make sense: Mindwipe possesses Mind Control powers and Skullcruncher is a giant gator who will crunch on your skull. And the rest of you.
In the IDW comics, Hardhead never actually becomes a Headmaster, but he still has a Meaningful Name. The guy shrugs off a shot to the face at point-blank range!
"Hard. Head. It's not just a name, you know."
In the IDW comics each member of the DJD is code-named after a Decepticon city - but even then it has some link to their personality or job - Tarn is the first city conquered by the Decepticons, and also the code-name of the leader of the DJD.
Almost every single character of Avatar: The Last Airbender has a name of Asian origin, varying from Mandarin Chinese to Korean slang. Given the theme of the show, the ones of non-Asian are often referenced and regarded as unusual to the other characters.
Zuko's mother is named Ursa (the Latin word for "bear"), displaying her role as his Mama Bear.
Zuko is once written as "Resurrected Rule", though another time it was "ancestors robber" on a wanted poster. It is logical to assume that his parents originally used the first "spelling", given that he was a royal child, and his father changed the "spelling" for the wanted posters to indicate that he had been disowned. Also, the first spelling of Zuko's name can also be translated to read "Reclaimed Honor". No really.
Swordsman Piandao of the episode "Sokka's Master" is named after a type of Chinese saber (though not the type he used, which is a jian).
Taking into account the Chinese characters used to write his name on the title card in "Tales of Ba Sing Se", Aang's name seems to mean "Ascending Peace".
Katara's name comes from a possibly phoenitic word of perhaps the same word, which means "beautiful." The individual parts of the name mean "block", "pagoda", and "pull."
Toph's name has a sextuple meaning: it is a kind of sandstone reflecting her element, a Hebrew word for "drum" referring to her ability to sense with vibration, a play on "tough" for her attitude, and a homonym of "toff", British slang for an upper-class person (which she is). On her passport in "The Serpent's Pass" her name is written to mean "supported lotus", which is indicative of how her parents saw her, as a fragile china doll. Conversely, on the title card in "Tales of Ba Sing Se" her name is written to mean "entrusted man".
The baby that the Gaang help deliver, who was given the appropriate but out of place name "Hope". The DVD Commentary said it was supposed to be a Chinese name that meant "Hope", but then either the meaning would be lost, or there would be a case of You Are The Translated Foreign Word.
The Earth King's name, Kuei (which is only mentioned in supplementary information) may be a transliteration of two words different words that respectively mean "chief" and "puppet", where as his Evil Chancellor Long Feng's name means "Dragon Phoenix", which in Chinese tradition represented the throne.
The north pole's princess and Sokka's love interest, Yue, has a double meaning as well, being in Chinese a word for moon, due to her being reincarnation of moon's spirit and in Japanese meaning a sad incident and used for children dying shortly after birth, such it might have happened to her, due to her being weak at birth.
King Bumi's name (Bumi) means "Earth" in Tamil.
Suki is a verb meaning "to like/love" in Japanese. Suki's name is also pronounced the same way as the Japanese word for the moon.
As the Fire Nation has largely Indian names, "Azula" is no doubt derived from "Asura". It fits her. Azula could also be seen as a modification of "Azul." Appropriate, as most of her firebending techniques are blue. In fact, it has been said that Azula was originally going to be "Prince Azul," before the Avatar folks decided to make her female.
According to the Avatar wiki, Ozai's name can mean either "leisurely year" (he spends a lot of time ordering others around from the comfort of his palace) or "flaming calamity", which...yeah.
In Mandarin, Zhao means "to look / search for (someone)". Guess what Admiral Zhao does throughout the first season.
The Owl-Knowing One, Wan Shi Tong, introduces himself to the Gaang as "He who knows ten thousand things". That is literally what his name means in Mandarin Chinese. For an added bonus "ten thousand things" is a saying in Taoism that basically means "everything", so by claiming to know ten thousand things, he's saying he is all-knowing.
Ba Sing Se's Secret Police, the Dai Li, is named after a real-life Chinese government official. The real Lieutenant General Dai Li was one of the most feared men in China, as he was the leader of Chiang Kai-Shek's secret police. Much like the Dai Li from the show, the real-life agents' assignments include surveillance, kidnapping, apprehension, and assassination.
Mikey Simon's stage name is, well, "Kappa Mikey." A kappa is a mythical Japanese amphibian. Ozu once explained that a kappa is a water creature that lives on land, and is thus a fish out of water, much like Mikey himself, who is an American living in Japan. Making things even weirder, kappas are said to like cucumbers and kappa makki is a type of sushi, meaning it's also a Punny Name.
There is a Yes-Man character actually referred to as "Yes Man" by everyone on the show. It's heavily implied that this is his actual name.
Gargoyles is interesting in that gargoyles do not have names normally, and past history had humans giving them a name, like Goliath.
When learning to trust Elisa, the various gargoyles of the Manhattan Clan chose names from their surroundings. Hudson, for the river, and Brooklyn, Lexington, Broadway, and Bronx.
When Demona has evil clones of the clan created (to go with Goliath's evil clone Thailog), she gives them names from Los Angeles neighborhoods/landmarks.
Demona herself is an interesting case: While she is certainly evil enough to merit the name, she wasn't that evil when she first got the name. (Her ally Macbeth gave it to her because, and I quote, "You fight like a demon!")
In many ways, Goliath's name is both played straight and subverted. In the first episode, he was named for having the strength of the biblical Goliath. However, it is also pointed out that the first Goliath was a bully and monster, something the gargoyle is definitely not. Furthermore, Goliath and his arch nemesis (DAVID Xanatos) invert the David Versus Goliath trope, providing another subversion.
There is also Fox's father, Reynard.
Though it's worth noting that Fox's birth name is Janine; she had it changed to "Fox," which is also what her last name meant (before she got married). Halcyon's first name may also be notable, since it sets him up as the "peaceful" analogue to his daughter and son-in-law.
Angela happens to have a karmically opposite name and world views to her mother, Demona.
The main bad guy from Samurai Jack is Aku, which is Japanese for "evil, wickedness".
In Duck Dodgers, the Martian Queen's name is Tyr'ahnee. (This is meaningful because it's a clever pun. She's the Big Bad of the series, and a line from the show's opening theme, spoken where she appears, says "Duck Dodgers is fighting tyranny.")
Butters' alter-ego Marjorine, which is a play on the word "margarine," a butter substitute.
And Mantequilla, which is Spanish for butter.
In "City Sushi", Butters attends therapy sessions with a psychiatrist named Janus, named for the two-faced Roman god of transitions. It's also worth mentioning that Janus suffers from dissociative identity disorder.
In one episode, a herbal medicine shop run by a woman called "Ms. Information" opens. She proceeds to convince the entire town that her products are much better than any kind of medical science, nearly getting Kyle killed by kidney failure.
Kim Possible includes minor villains Adrena Lynn ("extreme"-stunt TV host), and shapeshifting socialite Camille Leon, and the heroes, Kim Possible and Ron Stoppable. It's even lampshaded a few times. When Kim loses her memory, she says "'Kim Possible' doesn't sound like a name."
Matt Groening named the title characters after his own family; his parents are called Homer and Margaret, and two of his sisters are Lisa and Maggie. He drew the line at calling the boy "Matt", feeling that this would make the gag too obvious; instead he chose "Bart" because this is an anagram of "brat". He asked his animation team to come up with Grampa's name, and by sheer coincidence they chose "Abraham", the name of one of Groening's own grandfathers.
Judge Constance Harm. "Constance" means "unchanging", and "harm" is... well...
Larry Kidkill, who displays Apu's children at his zoo.
Career criminal, Snake Jailbird.
The FOX [network] censor from Treehouse of Horror VIII, literally named Fox Censor.
Arthur Fortune, the hip billionaire.
Subverted by Moral Orel with Mr. Nohammer, owner of Nohammer Hardware. Despite clearly having a sign that says "We Have Hammers" on his store and lining his store with wall-to-wall hammers, people still call him asking about whether or not he sells hammers. He's forced to constantly tell people "It's just my name!" * sob* .
Played straight with some of the other characters. Most are references to stop-motion animation (Clay, Shapey, Doughy, Putty) although Doughy's surname "Latchkey" refers to latchkey kids (his parents ignore him) and Ms Censordoll's initials are FCC.
In The Backyardigans, Word of God says that Uniqua is her name and herspecies. Ah, that's why she's so unique; all you gotta do is trade the A on the end of her name for an E. Also, the first four letters of Austin the kangaroo's name are the same as Australia, where kangaroos reside.
The parents on Rugrats were always taking advice from a doctor named "Lipschitz," whose advice was nearly always, well... just that.
In Aladdin: The Series, there's Abis Mal, Mechanikles, Ayam Aghoul, Amin Damoolah (though his name is ironic), Queen Hippsodeth, Harud and Abis Mal's ancestor Abnor Mal. In fact, his lack of a Punny Name could be the first indicator that Mozenrath is the Knight of Cerebus, and his name is still a pun, it's just a Shout-Out rather than a punny name with a meaning.
The one-shot villain Abracadaver, a zombie wizard whose name in life was Al Lusion.
Nerdy, paste-eating kid Elmer Sglue, who gets turned into a paste monster in one episode.
Sara Bellum, who does all of the real thinking involved with running Townsville (the Mayor is somewhat dim-witted.)
Sedusa, a combination of "seduce" and "Medusa", which perfectly describe her two superpowers.
To some degree, Professor Utonium ("Professor" can shorten to "Pr.", and befitting the Animesque style, this reads "Pr. Utonium"—which is how "plutonium" would be rendered, more or less, and the first two syllables also evoke the word "utopia", a perfect place, befitting his goal of creating the "perfect little girls".)
Lou Gubrious, another one-shot, who created a device that makes people sad. Formerly, when he was happier, he was called Hal Larious.
Blossom and Bubbles themselves were given meaningful names. Blossom because of her directness and opening right up to the Professor and Bubbles because she's cute and bubbly. Poor Buttercup.
Histeria!: Just listen to how Loud Kiddington and Froggo speak, and you'll see how they got their names.
The most obvious ones Ben Tennyson and Kevin E. Levin reflecting they're respective screen names Ben 10 and Kevin 11
Ben's alien transformations are named by Ben himself and so are more like superhero codenames, but whenever we do get the race's actual name, it's always a more scientific-sounding pun on what the alien does. Echo Echo is a Sonorosian, Wildvine is a Florauna, Big Chill is a Necrofriggian (the 'necro' part coming from his ghostly phasing ability), and all the Monster Mash aliens are from Anur Transyl.
Ben 10: Alien Force introduces Alan Albright, is the name of a young half-Pyronite, whose head is on fire half the time.
Ben 10 Alien Force exclusive characters: Manny Armstrong's (whose name reflects him possessing four arms and super strength), and his girlfriend Helen Wheels (whose name is a pun on Hell on Wheels').
Sushi Pack is rife with these. All the members of the Sushi Pack and the Legion of Low Tide are named after the type of sushi they are. Recurring villains Titanium Chef (a sushi chef), Sir Darkly (sadness and gloom personified), and The Collector also count, and one-shots A. Scientist and The Prevaricator (who can only tell lies).
Jimmy Two-Shoes takes place in Miseryville, which is Fire and Brimstone Hell. Thus, the characters include Lucius Heinous VII, named after Lucifer, the demon of pride, his son Beezy (which can only be short for "Beelzebub", the demon of gluttony) and Heloise (meaning famous warrior). Also, there's Jimmy's dog Cerbee, named after the three-headed dog in Greek Mythology, Jez, named after King Ahab's wife, and Molotov, named after Stalin's protege.
A Pup Named Scooby-Doo had a bully character named Red Herring, who Fred would blame as the monster Once an Episode. Given his name, it was never him except for the one time Fred made a agreement with the rest of the gang not to blame Red Herring.
The Looney Tunes: Daffy Duck, Bugs Bunny, Porky Pig, Tweety Bird, and so on. Wile E. Coyote goes a bit beyond just the name of the animal, as he is a wiley coyote (see what they did there?). And it gets cleverer — Pepe LePew is a Smelly Skunk (even though in real life skunks only smell when they spray) which makes everyone go pew! Speedy Gonzales is a speedy little mouse from Mexico. And Taz is a tasmanian devil.
Lampshaded in The Looney Tunes Show, where, after becoming a victim of Daffy's antics, Bugs responds with something to the effect of "no wonder your name is Daffy." When asked what that means, Bugs tells him to look it up. Which he does.
In Winx Club, with the exception of Bloom, all the girls' names reflect their power source. Flora is named after the Roman goddess of flowers and has power over plants, Stella (star) draws her powers from the sun and moon, Musa is reminiscent of musica (music), and Tecna is derived from tecnologia (technology). The Trix disguise this a bit with English-derived names: Icy (power over ice), Stormy (weather), and Darcy (darkness).
Nigel Uno (Numbuh 1): "Uno" is Spanish for "one" (though oddly, he's British).
Hoagie P. Gilligan, Jr. (Numbuh 2): Appropriately enough, a twofer reference: the surname "Gilligan" is from the eponymous second in command of the Minnow on Gilligan's Island; the generational suffix "Jr." is also meaningful, as "Jr." is used at the end of most men's and boys' names to signify that they were named after their fathers [if their fathers had no other males in the families with the name given to their sons prior to their sons' births] and are considered second generation.
Also, a hoagie is a type of sandwich, and Numbuh 2 liked to eat a lot.
Kuki Sanban (Numbuh 3): "Sanban" is Japanese for "third" (san "three", -ban is a Japanese suffix used in creating ordinal numbers); "Kuki" is a reference to her ditzy personality ("kooky"). Her evil little sister's name, Mushi, translates as "insect," her irritable father Kani means "crab," and her mother is Genki (more likely a reference to Kuki, as Genki doesn't act like her namesake).
Wallabee "Wally" Beatles (Numbuh 4): The Beatles had four original members (even though Wally is Australian, not Liverpudlian). Numbuh Four is also the unluckiest member of the group (which is a reference to the Chinese belief that the number four is bad luck [much like the number 13 in Western culture]).
Abigail Lincoln (Numbuh 5): Has same initials as Abraham Lincoln; Abraham Lincoln's face is on the $5.00 bill.
Numerous other characters also have names and numbers related to their function within the show (e.g., the operative who decommissions is Numbuh 86; submariner Numbuh 20,000; Numbuh 10-Speed of the KND Central Bike Hub is named Lance [as in Armstrong]).
Teen Titans has Terra (uses earth based powers), Jinx (creates bad luck; AKA "jinxing" something), Gizmo (uses gadgets), Mammoth (large in size and uses strength), and Cyborg (half-robot, half-human).
Savage Opress. Go on, guess what side he's on. (However, he actually wasn't so bad before he was chosen as Dooku's new warrior and the Nightsisters messed with his head. His brother Feral also shows no sign of overt evilness, though in both cases, you gotta assume nobody connected with the Nightsisters is a saint.)
Tutenstein gives us Cleopatra "Cleo" Carter, Egypt enthusiast and Secret Keeper of a resurrected pharaoh. Her first name is obvious, while "Carter" alludes to Howard Carter, the archaeologist who found the real-life Tutankhamun's tomb.
The cast of SWAT Kats. They're all cats, and most are named after cat species.
Commander Bem, an alien from the planet Pandro in the Star Trek: The Animated Series episode "Bem". Bem is a science fiction acronym for "Bug Eyed Monster".
"The Balloon People". The villain Dr. Noah Tall (Know-It-All) desires knowledge in order to gain power, so he wants to "know it all". His not-too-bright assistant Twisty regularly uses Spoonerisms, indicating his "twisty" mind. The chief of the U.S. Government's Environment Protection Bureau is named Simon Pure.
The villain Dr. Shamon. He has a giant magnet in the shape of the letter U, and the episode is titled "The Shamon U" (shame on you).
"The Androids". Dr. Rebos' assistant is named "Loco", and he acts in a stupid and (borderline) crazy manner.
"The Fantastic Frerps". The villain King Plasto is obsessed with using plastic. He has two assistants named Styro ("styrofoam") and Polly Ethyl Lene ("polyethylene").
"The Mysterious Moles". The villains have a Giant Underground Drill that they use to dig down to the bottom of a cave. Their names? Minnie and Maximus Mole.
"Gulliver's Gigantic Goof". A scientist named Gulliver is determined to shrink the entire world population down to a tiny size.
"Too Hot To Handle". Professor von Knowalot (know a lot). Kobar's home planet is normally quite hot (140 degrees Fahrenheit), and is called Solar Terrarium.
"The Water People". An undersea researcher with his own submarine is named "Professor Matey" (as in "Ahoy, matey!").
G.I. Joe, in all its incarnations is made of this, as most of the characters have names or code-names closely related to their specialties.
Duke, the all-American hero, is named after John Wayne.
"The Devil's Tower". The villain is named "Von Deufel", very similar to "Teufel" ("devil" in German).
Dr. Zin. If you flip the "Z" you get an "S" for "Sin".
WordGirl has a great vocabulary. The Butcher not only has meat-relates superpowers, but also butchers the English language. And Lady Redundant Woman's name contains redundancy in containing "Lady" and "Woman".
Twilight Sparkle: She brings peace between the day and the night, earning the twilight part, while the sparkle refers to her ability with magic as well as "the spark" she feels in the series premiere upon her epiphany that she has come to consider the other characters her friends (a bit of symbolism that is reinforced by the five small, six-pointed stars orbiting the larger one on her cutie mark, which she earned in an incident that linked all six characters' lives together before they even met; magic is her special talent, but friendship IS magic, after all).
Rainbow Dash is a super speedy pegasus with a rainbow mane and tail.
Fluttershy is very shy. Her name's a play on "shutterfly" after all (which originated from her G3 incarnation, where she was a photography enthusiast). Her cutie mark is three butterflies, which sounds similar to 'Fluttershy'. She's also shown to be a poor flier, meaning she's 'shy' about flying (or 'fluttering' her wings, so to speak.)
Applejack is an apple farmer. Pretty straightforward, really. Also goes for Apple Bloom, Big Macintosh, and Granny Smith.
Rarity has the ability to magically detect rare gems, is a master of elegant presentation, and is considered exceptionally beautiful.
Pinkie Pie is not only colored pink and works in a bakery, but the fact that she has by far the most off-puttingly "girly" name of all the characters is fitting not because she's especially feminine, but because she is a parody of the characters that populated previous My Little Pony shows, taken to their logical extreme.
Princess Luna controls the moon. Notably, her sister and counterpart Princess Celestia has a name more closely related to the heavens in general than the sun. Of course, when she's first introduced she has control of both the sun and moon, and to this day the less-experienced Luna defers to her authority.
Princess Cadance's full name is Mi Amore Candenza, which means "my love cadence" in Italian. Spreading love and harmony among ponies is Cadance's special talent. This also descends into Fridge Horror when one takes into account that Queen Chrysalis, who spends most of "A Canterlot Wedding" impersonating Cadance and insisting that others address her by her full name, feeds on love and was effectively making the ponies say they love her.
Shining Armor, though not technically a knight, is Captain of the Royal Guard, and his special talent is defensive magic.
Silver Spoon and Diamond Tiara. The former is a useless rich girl, while the latter actually wears a diamond tiara that matches her cutie mark.
Spitfire (named after a World War II fighter plane) and Soarin are members of a professional flight team.
The queen of the insectoid, shapeshifting Changelings is named Chrysalis, which is what insects use to metamorphosize into their mature form.
King Sombra in Season 3, whose name means "shadow" in Spanish - appropriate, given that he spends most of "The Crystal Empire" in the form of a huge, dark cloud Made of Evil. This is also evocative of the word "somber" (gloomy), which references the misery his subjects had to suffer through during his rule.
Really, most My Little Pony characters, Friendship is Magic or otherwise, have a Meaningful Name that either refers to their personality, species, or design (most often their cutie mark).
In W.I.T.C.H., Will's given name is Wilma, though it was originally Wilhelmina in the comics. The name from which it is derived, Wilhelm, is formed from two words: wil (will or desire) and helm (helmet or protection)—thus, it could be construed to mean desire/will to protect, very fitting for a Guardian of the Veil. There's also the obvious significance in that the first letter of each of the girls' names spells out witch.
Caleb's name could also be significant. There is a character in the Bible named Caleb who was sent by Moses into Israel as a spy. He was also one of only two of said spies to live to see the Promised Land. The name itself means dog, which could also speak to Caleb's loyalty.
Along with several Bilingual Bonuses: businessman's daughter Kimiko (Japanese for "Noble daughter"), The Chosen OneMaking a SplashOmi (Yoruba for "Water," along with Finnish possessive article "own", though this may be a coincidence), and the winner is Raimundo (Spanish for "Wise protector") who becomes Team Leader at the end of the series.
Team Umizoomi gives us Milli (a latin prefix for "thousand", explaining her measuring abilities. Also may be based of the word "chameleon" due to her pattern power), Geo (a greek prefix for "earth", but mostly his powers relate to Geometry), and Bot who is, well, a robot!
Dipper Pines of Gravity Falls is named so because he has a birthmark on his forehead in the shape of the Big Dipper.
Animaniacs: Yakko and Wakko. Yakko's name is a play on "yakking away" or talking incessantly. Yakko almost never shuts up. Wakko's name is a play on "wacko", as in someone who is a little wacky, like Wakko.
Adventure Time: Marceline's name means longevity which means that she has a long life due to her being a Vampire.
The Ice King's name is Simon Petrikov. "Petri-" means frozen.
In Sym-Bionic Titan, Lance's title is "Corporal Lance", a reference to the military rank. The armor of the lead trio are named Corus, Manus, and Octus, which refers to heart, hands, and eyes; similar to the "Heart, body and mind" ideal on Galaluna that ends up making up their Sym-Bionic Titan form. When Octus takes a human form, he takes the street name "Newton," a reference to Sir Isaac Newton. Solomon, the leader of G3, at one point uses the alias Kane which would make his name Solomon Kane.
In Motorcity, the protagonist is named Mike Chilton, his surname as reference to the Chilton Company, which publishes automobile repair manuals (in a car-themed car). The Big Bad and his daughter have the surname Kane, another Name of Cain. The team's engineer is named Dutch Gordy and has a robot named R.O.T.H., both references to artists (Kenneth "Von Dutch" Howard and Ed Roth). His surname, Gordy is from Berry Gordy, founder of Motown.note In Detroit
Mr. Bone has a nephew named Percy Femur, a rather large kid who ends up bullying Roger and Doug. The femur (or thigh bone) is the largest bone in the human body.
In the UK cartoon Happy Ness: The Secret of the Loch, the Nessies' name undoubtedly match their personalities. (Happy Ness, Lovely Ness, Kind Ness, Dark Ness etc.)
The same goes for the earlier The Family Ness. (Ferocious Ness, Silly Ness, another Lovely Ness, Clever Ness etc. and their ruler Her High Ness.)
Corey Riffin's middle name in Grojband, Jaron, comes from the Hebrew name meaning Yaron, which means to sing or shout phrases. This connects because Corey's a singer and he's always singing and shouting.
The Raccoons: A conman named Sid Leech tries to take advantage of Simon Sneer's disappearance by impersonating him and stealing his inheritance.