Vampire Bites Suck: In the Showa era, the bites suck since you could be killed by a single chomp.
Weakened by the Light: The Showa version doesn't like the sun, and in fact would die if exposed to the ultraviolet rays for too long. The Heisei ones also preferred night at first but after growing protective eye plates they could fly during the day without much hassle.
Beware My Stinger Tail: Has a deadly stinger hidden in her tail she can use to implant her offspring in other monsters.
Dangerously Genre Savvy: Spends the entire film trying to destroy the one weapon capable of defeating her, impales Gamera's arms and knocks him on his back to disable him, and generally proved to be one of the most cunning foes Gamera has faced. In fact, she's the Gamera foe who came the closest to killing him in the Showa Era!
Disintegrator Ray: Her heat ray vaporizes flesh and entire city blocks. Doesn't have the same affect on Gamera, but still damaging nonetheless.
Face Full of Alien Wing-Wong: Implanted an egg into Gamera's lung, stunning him. It hatched in his lung and would have probably made its insides a meal if the heroes hadn't killed it.
Hell Is That Noise: In-Universe, her main weakness is an idol that makes a sound that's able to both weaken her and cause severe illness in humans. White noise is also discovered to be this to her. Her Disintegrator Ray also opperates on this.
Monster Is a Mommy: And she will use the nearest monster as the incubator for that egg. Gamera is free.
Sealed Evil in a Can: Was sealed away under the earth by the Devil Whistle thanks to it making a special sound which weakens her, keeping her in suspended animation.
Superpower Lottery: Can shoot quills that keep Gamera in place and take down jets, a massively destructive heat ray, the ability to suck opponents toward her, and impregnate opponents with her stinger tail.
Ambiguously Evil: Multiple possible explanations are given for his existence, some of which imply he was actually not inherently evil and was corrupted by Ayana's hatred. While he's undoubtly a dangerous monster and the film's main villain, it's unclear if he does the things he does out of a malicious nature or simply because he thinks its what he thinks Ayana wants him to do.
Woobie, Destroyer of Worlds: She lost her parents during the battle between Gamera and the first Super Gyaos, her adopted family openly talks bad about her, she and the one part of her foster family she cares about are bullied by the neighborhood. Yeah, she's directly responsible for Iris (and depending on which choice you pic from his Multiple Choice Past, perhaps directly responsible for what he became), but the poor girl's been through hell.