- Beam Me Up, Scotty!: Matador is known for saying, "I challenge you to a duel!" However, contrary to popular belief, that's not the whole sentence. The full sentence is, "I challenge you to a duel, to see which of us is truly worthy of the candelabra..."
- Fan Nickname: The phenomenon of Mot spamming Beast Eye to give itself a ludicrous number of turns and then using Megidolaon repeatedly to nuke the player's party senseless is known by Japanese players as "Mot's Drama".
- Missing Trailer Scene: The Demi-fiend's only spoken line, "Tokyo died, and I was given life", only appears in the first 2003 Japanese commercial and, as a Call-Back to that commercial, the first HD remake trailer.
- Newbie Boom: While Atlus had attempted to bring over Shin Megami Tensei games to the west before, including the infamously bad port of the first Persona and skipping Innocent Sin in favor of Eternal Punishment, confusing a lot of people in the process, This game in particular was popular enough to start getting the trend of Truer to text Shin Megami Tensei titles being brought to the west, culminating in the breakout popularity of Persona 3 onwards later down the line.
- No Export for You:
- Of the multiple editions of the game, only the Maniax and HD Remaster Updated Re-releases made it out of Japan.
- Raidou was removed from the HD Remaster in Korea and China due to his outfit's similarity to Japanese military uniforms used during the era the Japanese military committed various war crimes in those countries.
- Role Reprise: Tomokazu Sugita and Joji Nakata reprise their respective roles as Raidou and Gouto from the 3DS remake of Soul Hackers, which in turn was a reprisal from a 2009 drama CD.
- Screwed by the Lawyers: One possible reason why the upcoming HD Remaster is based on the Chronicles version (which replaces Dante with Raidou) is that Atlus probability didn't want to pay Capcom any licencing fees.
- Sequel First: This was the first mainline SMT game to be released outside of Japan. And even then, it was the Updated Re-release that made the export, rather than the vanilla edition.
- Sequel Gap: Released nine years after Shin Megami Tensei II in 1994. And that's if you live in Japan.
- Word of Dante: While there is no official word on who Jyoji really is and what sin he committed, it has been accepted in pretty much the entire fandom that he is Aleph from Shin Megami Tensei II.
- Working Title: The game was known as Shin Megami Tensei: Vortex during development.
Trivia / Shin Megami Tensei III: Nocturne