- Channel Hop: This film was distributed by Universal after Warner Bros. refused to distribute the films. Fortunately, New Line Cinema (sister company of Warner Bros.) was still attached, but credited as a production company.
- Dueling Dubs: In Latin America, there's three dubbed versions: One for Argentina and two other ones dubbed in Mexico. The Argentinian dub was the one used in Latin American theaters (even in Mexico, when non-Mexican dubs are barred from being shown in the theaters of that country, oddly enough), while the Mexican dubs are used exclusively in home video releases.
- The Other Darrin:
- In the Japanese dub, Harry is voiced by Toru Okawa, replacing the late Nachi Nozawa in the same role. On the other hand, Kōichi Yamadera reprise his role as Lloyd.
- An inverted case of the above happened in the first Mexican Spanish dub, where it was Lloyd whose voice actor got replaced, in this case he is voiced by Mario Castañeda, Jim Carrey's regular dub voice actor in Mexico, while in the first movie, he was voiced by Salvador Delgado. On the other hand, Martin Soto reprised his role as Harry.
- Saved from Development Hell: It only took 20 years...
- Sequel Gap: The film was released 20 years after the first movie. And as a bonus, the movie takes place 20 years after the events of the first movie.
- What Could Have Been: During the film's production, Jennifer Lawrence was in talks to have a cameo as a younger Freida Felcher, but ultimately it didn't end up happening.
Trivia / Dumb and Dumber To