Season 1, Episode 03:
Directed by John Rice
Rick: You got a problem with that last one, Morty?
Morty: Huh? No, no. I'm just reading 'em out loud in the order that I'm seeing 'em.
Rick: Okay. All right. If I sounded a little defensive, it's because... Pirates of the Pancreas was my baby. You know, I got I got a lot of pushback when I pitched it, Morty. I guess I'm still a little defensive.
Rick shrinks Morty in order to send him into the body of a homeless man to help him with a nanoscale theme park built inside of his body. Meanwhile, Jerry makes his family give up their various technologies so they can bond as a family in honor of his parents' visit for Christmas, only to regret it when they introduce him to their new black "friend" Jacob.
- Always a Bigger Fish: The Hepatitis A is killed by an even bigger and more monstrous Hepatitis C.
- Amusement Park of Doom: Anatomy Park is in pretty poor repair and is full of diseases trying to kill the characters. The Liver, in particular, is in full-on spooky abandoned theme park mode.
- Big Damn Heroes: Parodied when Morty and Annie are saved when a Hepatitis C virus defeats a Hepatitis A. They are confused, given that they've had no connection with him before, and they assume he's naturally benign.
- Fridge Horror kicks in when you realize it could also mean that Annie is infected with Hepatitis C, meaning the one rescuing them is simply indirectly protecting its own kin.
- Body Horror: Given the plot, this episode is rife with it.
- Brick Joke: When Jerry asks his parents what is their relationship with Jacob, they explain that Jacob is Joyce's lover in a cuckold, while Leonard watches them "sometimes from a chair, sometimes from a closet, almost always dressed as Superman". Later, Joyce and Jacob are making out and Leonard goes into a closet wearing a Superman suit.
- Christmas Episode: Aired on 16 Dec 2013. Reuben looks a lot like Santa Claus.
- Cluster F-Bomb: Rick in The Stinger."Fuck them. Fuck those people. Fuck this whole thing, Ethan!"
- Distracted by the Sexy: While Morty and Annie are making out, Rick tells Morty to put the volume on mute because it is causing him to lose focus.
- Dwindling Party: Those who are inside Reuben start dying one by one, until only Annie and Morty are left.
- Everyone Is Christian at Christmas: The episode ends with Rick of all people ranting about his family being on their phones on Jesus' birthday without any hint of sarcasm.
- Executive Veto: In-Universe example. The Stinger had Rick's Pirates of the Pancreas ride axed by the Chief "Imagineerian".
- "Fantastic Voyage" Plot: Poor Morty was shrunken down and injected into the homeless man's comatose body. Deconstructed when the people inside end up causing Reuben's death and what we end up seeing is what happens to a decomposing body.
- Flatline: We know that Reuben is dead when the flatline sound rings out in Rick's garage.
- Help, I'm Stuck!: Roger's foot gets stuck which turns out to be lethal for him.
- Heroic Sacrifice: Dr Bloom stays behind to start the bone train with Morty and Annie in it. Then he realises that there was an autopilot and regrets his decision. But it is too late.
- Innocent Innuendo: Dr. Bloom asks Annie and Morty if they want to "ride the bone train" which in this case is a literal train in Rueben's skeletal system. Morty blows up on him when Bloom keeps trying to push the actual innuendo at an inappropriate time:"Why are you doing this bit?! We're gonna die; let's go!"
- Inside Job: Dr. Bloom assumes that the stuff that's been going on in the park is the result of one; the culprit is eventually revealed to be Poncho.
- Killed Mid-Sentence: Alexand... and Roger.
- Monstrous Germs: The various diseases that live in Ruben's body are hideous monsters that look nothing like real germs. Some at least show a resemblance to actual bacteria or viruses, but usually the wrong type (Tuberculosis is portrayed as orb-shaped when it should be rod-shaped, and E. coli, a bacterium, looks like a bacteriophage virus), and then there are the Hepatitis viruses that seem to be designed after the Rancor or the Cloverfield monster.
- No Dead Body Poops: Dr. Bloom notes that the sphincter dam, constructed when Ruben became incontinent, was not designed to hold back a corpse-load.
- No Phones Tonight: Jerry confiscates everyone's electronic devices so that they can have a traditional, intimate Christmas together, but it backfires when he gets upstaged by his mother's lover. The episode ends with Jerry happily giving everyone their devices back.
- Ominous Floating Spaceship: Reuben's giant corpse casts a menacing shadow all over America.
- Polyamory: Jacob turns out to be Jerry's mother's lover. His father watches them, almost always dressed as Superman.
- Pre-Asskicking One-Liner / Pre-Mortem One-Liner: Poncho delivers this line before igniting the gas in Reuben's body around Gonorrhea.Poncho: Hey, Gonorrhea! How's this for a burning sensation!?
- Rain of Blood: Literally, when Rick blows up Reuben's enlarged corpse in space.
- Reality Ensues
- Actions of the people inside Reuben end up causing his death, so they have to figure out a way out of his body before it decays.
- Rick may be a scientific genius, but even he can't bring a corpse back to life.
- Serious Business: Rick is very protective over his "Pirates of the Pancreas" attraction and is severely pissed when it gets dropped from his second attempt at Anatomy Park. Becomes a Running Gag.
- Sound-Effect Bleep: Done to Rick's cursing in The Stinger.
- The Stinger: Rick has Annie head a crew to build a new Anatomy Park inside Ethan's body, but becomes outraged that they have different ideas for his beloved "Pirates of the Pancreas" attraction.
- Talking Is a Free Action: Averted: In the time it took for Rick to talk about curing Reuben's Tuberculosis, he could've just cured it then and there.