- Resident EvilIntroducing
- Resident Evil 2Introducing
- Resident Evil 3: NemesisIntroducing
- Resident Evil Gun Survivor Introducing
- Resident Evil – Code: VeronicaIntroducing
- Resident Evil 0Introducing
- Resident Evil OutbreakIntroducing
- Resident Evil 4Introducing
- Resident Evil: The Umbrella ChroniclesIntroducing
- Resident Evil: DegenerationIntroducing
- Resident Evil: The Darkside ChroniclesIntroducing
- Resident Evil: RevelationsIntroducing
- Resident Evil: Operation Raccoon CityIntroducing
- Resident Evil 6Introducing
- Resident Evil: DamnationIntroducing
- Resident Evil: Revelations 2Introducing
- Resident Evil 7: biohazardIntroducing
- Resident Evil: VendettaIntroducing
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Voiced by: Karen Dyer
"Don't worry. I may not be as big as you, but I can still hold my own!"Chris' partner during 5, with whom he develops a strong bond. She joined the BSAA to fight against biological weapons since her parents had been victims of experiments carried out in Africa with said weapons.
- Action Girl: She can and will kick just as much ass as Chris does.
- Badass Normal: She's just a girl with a gun, she doesn't even have the experience fighting B.O.Ws that Chris does, and yet she doesn't back down for a second as she faces deformed psychopathic killers and horrible mutations.
- Bilingual Bonus: Her tattoo reads "Shujaa," which is Swahili for "Hero."
- The Chick: For her team.Josh: Sheva became the little sister of the team.
- Colour Coded Characters: Production notes state that it took the team a while before deciding on her signature color — lavender.
- Dark and Troubled Past: Her parents and village worked for an Umbrella facility as menial laborers. When she was a child, Umbrella used the workers for experimentation; her parents died and she was taken in by her uncle, who lived in poverty with his seven children. Unable to feed herself and convinced her parents were still alive, she ran away, but almost died wandering the savanna. She was rescued by anti-government guerrilla fighters, who explained how Umbrella had destroyed her village and killed all the survivors when she was done, with the help of the government, so she joined with them to make Umbrella and the government pay. When she was a teenager, she found out that her "friends" were actually going to buy bio-weapons from Umbrella to overthrow the government, which was all they really cared about, so she helped sabotage the deal. For this, she ended up being taken to America and adopted, after which she eventually joined the BSAA and returned to her native country to continue her quest.
- Fur Bikini: One of her alternate costumes.
- Good Is Not Soft: Even amongst the other player characters, Sheva stands out. She is one of the nicest characters in the series, especially if you build up her trust, established to be just as good as Chris, Jill, Leon, or Claire, and in the final boss fight, you can have her do one of the most badass things in the series and turn Wesker's chest into a scratching post.
- Heroic Sacrifice: She was about to perform one, but Chris saved her from herself.
- Hotter and Sexier: One of her alternate costumes is a sexier version of the Little Red Riding Hood
- Knife Nut: Sheva will straight-up shank a fool if given the opportunity, including Wesker. While he's infected with Uroboros.
- The Lancer: For Chris.Sheva: There's only so much one person can do. Even a superhero like you, Chris.
- Male Gaze: The first thing you're shown of her is pretty much her ass. Lampshaded by Unskippable.
- No Celebrities Were Harmed: Her "Clubbin'" alternate costume is visibly inspired by a similar outfit worn by Halle Berry in Swordfish.
- Shout-Out: One of her alternate costumes is a throwback to Hunnigan from 4.
- Sexy Secretary: One of her alternate costumes is of a Sexy Secretary with a Badass in a Nice Suit vibe.
- Stepford Smiler: She outrightly defies this trope based on analysis. Despite her tragic background, she refuses to be a let down, and instead keeps a healthy and upbeat attitude. Most characters in her position are usually The Stoic, The Woobie, etc. If you just met her and didn't know her, you would think her life was sunshine and rainbows.
- True Companions: She's pretty much about this, either for Chris or for her team.
- Unwanted Assistance: In-Universe. She becomes this if you allow her to carry all the healing items while you prioritize yourself with weaponry. If you sustain so much as a scratch she'll chase after you and try to waste the best herb/spray items futilely fixing you up. Cue Benny Hill chase.
- What the Hell Is That Accent?: It sounds like like she's trying to pull off an Afrikaans accent, but ends up sounding British.
Voiced by: T.J. Storm
The captain of BSAA West Africa Branch and Sheva's mentor. He becomes Jill's partner in DLC, Desperate Escape.
- Black Dude Dies First: Averted. He survives the entirety of RE5 — in fact, he's the only BSAA West Africa teamster in the game who does survive the game, aside from Sheva.
- Chivalrous Pervert: A minor example. He flirts with Jill for a brief moment after they first meet, but he keeps the relationship professional afterwards. His partner, Doug, teases Jill a bit more with his flirting, though he's likely just goofing around as a part of his personality.
- The Good Captain: Of BSAA West Africa.
- Lower-Deck Episode: A DLC campaign ("Desperate Escape") in Resident Evil 5 allows you to play as him and Jill Valentine trying to escape from the Tricell headquarters.
- The Mentor: To Sheva.
- Tall, Dark, and Handsome: Hailing at 6'1".
- Wrestler in All of Us: His melee takedowns include elbow drops, German suplexes, and chokeslams.
Ozwell E. Spencer
Voiced by: Adam D. ClarkeA British lord and one of the three founders along with Dr. James Marcus, and Edward Ashford of the Umbrella Corporation, is also the President of the Umbrella Corporation, who set in motion the events of the entire series in an attempt to make a new, superior race with himself ruling over it.
- Aristocrats Are Evil: He's a Lord......his last name is perhaps a Shout-Out to the venerable Spencer family, of which Princess Diana was a member.
- Bad Boss: In "Lost in Nightmares" from Resident Evil 5, you can read diary entries of those who worked in Spencer's mansions. It seems he turned a lot of them into test subjects, and ultimately into monsters and zombies.
- Celebrity Resemblance: His voice actor, who is a self-admitted Star Wars fan, based his voice on that of Ian McDiarmid's role of Emperor Palpatine, with Spencer himself being modeled after the man.
- The Chessmaster: He's been running everything since well before the events of Resident Evil 0.
- Chronic Backstabbing Disorder: Kills Marcus through Wesker and Birkin, betrays the latter for attempting to leave Umbrella, betrays George Trevor by locking him inside his mansion, and lastly betrays Wesker by admitting he is his creation.
- Cutscene Boss: After waiting numerous games to meet Ozwell E. Spencer in the flesh, Wesker kills him in a cutscene. Although, fighting an 89 year old man on life support probably would not have been an epic boss battle, even with the potential for mutagenic viral upgrades.
- Dark Lord on Life Support: The years have clearly taken their toll. He was even the page image for a time. He's reduced to being confined to a wheelchair and life support system three years before Resident Evil 5 due to his old age. He expects Alex Wesker to reverse this condition by engineering an Immortality virus, although Albert Wesker kills him to become the Big Bad after Spencer reveals that Wesker was one of many Unwitting Pawns for Umbrella known as "Wesker children" in a project done to create the perfect breed of humans.
- Evil Cripple: He's in a wheelchair when Wesker finds him.
- Evil Old Folks: 89 when he dies.
- A God Am I: Or so he dreamed. "I was to become a god!"
- Greater-Scope Villain: He's The Man Behind the Man to all of Umbrella, including Alexia, Sergei, Birkin, and the series' most recurring villain, Albert Wesker. Yet, he is rarely seen throughout the series and doesn't even interact with the protagonists.
- Immortality Seeker: Had Alex Wesker work to create a virus that would render him immortal. Alex stabbed him in the back after looting his resources.
- Impaled with Extreme Prejudice: How Wesker kills him, using his bare hands.
- Mad Scientist: It goes overlooked, but he was part of the research team who originally studied and refined the Progenitor Virus.
- The Man Behind the Curtain: He's behind all the bad stuff in the series, whether directly or indirectly, but he's little more than a pitiful old man, whining about how he was unable to achieve godhood.
- The Man Behind the Man: To Sergei, who's his Dragon-in-Chief, Alexia, and Birkin (who he employs), and in an odd way, Wesker, who he created.
- Meaningful Name: He shares a last name with Herbert Spencer, the philosopher who conceived Social Darwinism.
- Nice Job Fixing It, Villain!: If Spencer didn't order Wesker and Birkin to assassinate Dr. Marcus, none of the events relating to Umbrella's downfall and afterwards would have happened.
- Non-Action Big Bad: Par excellence. All the evil that Umbrella inflicts can be laid at his feet, yet he never actually does anything on his own; he just gives orders from behind a cushy desk, far, far away from all the blood and tears.
- Smug Snake: Smart and a capable schemer, he's behind almost every bad thing in-series, but he waited too long to put his plan in motion, allowing Wesker to hijack it for himself.
- The Unfought: The heroes never even meet him alive. He's already been killed by the time Chris and Jill bust into his chamber.
Voiced by: Nina Fahren
"You're just not ready for me!"Excella is the CEO of Tricell Africa and one of the people responsible for the creation of the Uroboros Virus. She also shares Wesker's idea of World Domination and intends to be the Queen of the new world with Wesker as her King.
- Absolute Cleavage: See the image.
- All Girls Want Bad Boys: She was in love with Wesker of all people!
- Armor-Piercing Slap: Has the literal version in Mercenaries Reunion. And yes, her slaps can make enemies' heads explode.
- Asshole Victim: Infected with Uroboros by Wesker during the penultimate chapter. Considering the things she's done, no one is shedding any tears.
- Brainy Brunette: Evil Brainy Brunette.
- Combat Stilettos: She keeps her high heels in Mercenaries Reunion.
- Dark Action Girl: Though she doesn't fight in the actual game, on Mercenaries Reunion, she kicks ass with vicious elegance.
- The Dragon: To Wesker.
- Et Tu, Brute?: On the receiving end of this, though seeing this is Wesker we're talking about, it's really no surprise.
- Everyone Looks Sexier If French: Sort of. She possesses a French Accent, but her last name is closer to that of Italian.
- Femme Fatale: Subverted. She has all it takes to be one fierce Femme Fatale — beauty, intelligence, and cunning — but she is the one who falls for Wesker's masculine wiles and pays for it.
- Hot Scientist: She majored in genetic engineering.
- Omnicidal Maniac: Excella agrees with Wesker's plan in Resident Evil 5, which would include killing, at the least, billions of humans.
- Say My Name: ALBEEEEEERRRT!!!
- She-Fu: Her Disco Spin move.
- Statuesque Stunner: 5'9".
- Stripperific: A backless mini-dress and pumps is not the appropriate attire for running around the African jungle or an oil rig.
- Unholy Matrimony: With Wesker, though they weren't indeed married to each other but in her head...
- Woman in White: Though it's not played for mystery or necessarily to show that she is evil.
- Woman Of Wealth And Taste: Her dress and shoes are both based on pieces by real life haute-couture designers. Her jewels look just as expensive and chic.
Voiced by: Allan Groves
"Splendid timing! Youse two are just in time for the fireworks show! Boom!"Director of the oil facility headed by Tricell Africa, Irving helped found its B.O.W. research department, and subsequently became known as a "death dealer" on the black market for distributing the products Tricell developed to African bioterrorists. Chris and Sheva going to Africa to capture him is what kickstarts the events of Resident Evil 5.
- Defiant to the End: Upon his death, he keeps laughing and mocking Chris and Sheva:Irving: "Dying's not so bad. But it doesn't change anything... you're still screwed!" (cue Evil Laugh)
- Disc-One Final Boss: The first part of the game is all about chasing him, investigating him, and arresting him — it's only upon his defeat that he lets it slip he was merely following orders from Tricell's CEO, Excella.
- Expy: Many fans compared his behavior to that of Salazar from Resident Evil 4. Both are psychotic and over-the-top villains with heavy accents (Irving's Chicago accent in comparison to Salazar's hispanic) that transform into giant monsters by using a Dominant Plaga strain, while retaining their overall intelligence even after mutation.
- Large Ham: Especially once he goes One-Winged Angel.Irving: I just had an EXTREME MAKOVAH!
- One-Winged Angel: A gigantic sea-beast most comparable to The Kraken.
- Screw This, I'm Outta Here!: Attempted this after failing to kill Chris and Sheva. It didn't work out for him.
- What the Hell Is That Accent?: His accent sounds either Brooklyn or New Jersey.
- You Have Outlived Your Usefulness: By being forced to infect himself with a dominant-strain of Plaga.
- "You'll be pleased to hear that all experiments are running smoothly."
Though Majini make up the bulk of the enemies you face in this game, Tricell has a few artificially engineered monsters to face off against as well.For the tropes pertaining to the Majini, see the "Las Plagas and Hosts" folder in Resident Evil 4.
PopokarimuA genetically engineered hybrid of a giant bat and an insect, created by Tricell as a conventional B.O.W. Chris and Sheva fight two of these creatures, one prior to entering some caves, one within the ancient city of the Ndipaya tribe.
- Advancing Boss of Doom: If you try to flee the second Popokarimu, it will chase you up the stairs, and you need to Press X to Not Die.
- Attack Its Weak Point: You can only kill one of these things by shooting it in its head (less effective) or by going for the soft, fleshy underbelly of its insect-like abdomen. Bullets will just bounce off of its armored carapace otherwise.
- Beware My Stinger Tail: They can bodyslam, sweep, pincer-bite and launch Super Spit from their tail.
- Giant Flyer: A flying bat-bug thing the size of a large car.
- Mix-and-Match Critters: Half bat, half insect, looking like a giant, deformed bat with a grub replacing its lower body.
- Super Spit: They spray gouts of Hollywood Acid from their tail.
UroborosThree different mutants that Chris and Sheva encounter art different points of the game; Test Subject, Mkono and Aheri, but all are fundamentally identical where it matters. All are humans infected with the Uroboros virus, but unable to control themselves after the infection, resulting in them transforming into out-of-control mindless abominations.
- Attack Its Weak Point: Those big vaguely glowing yellow-orange blobs are their "cores". Only by shooting them will you stand a chance of putting these things down.
- Attack of the 50-Foot Whatever: Comparing Aheri to the ship you fight it on suggests it's about seventy feet tall, one of the biggest monsters in the entire series.
- Blob Monster: They have certain similarities to this. They can absorb flesh and use that to grow bigger and bigger, which is how Aheri managed to get so huge.
- Body Horror: Phase one of Uroboros infection; you are eaten alive from the inside out by writhing, pulsating black worm-like shapes which knot together into once larger whole. It gets worse from there.
- Kill It with Fire: The best way to get rid of an Uroboros is to burn it to pieces. You can instantly dispatch the Test Subject by trapping it in an incinerator, you can kill Mkono more easily with a flamethrower provided for just such a situation, and you can kill Aheri with a satellite laser.
- Was Once a Man: Every Uroboros was originally a single human who was infected with a virus. You really, really can't tell anymore.
- Worm That Walks: Uroboros have this sort of look, seemingly being made of countless black worms all swarming together.
ReaperCommon African household cockroaches accidentally exposed to Uroboros, the Reapers demonstrate that virus' extreme potential for deadly mutation, having transformed into killing machines.
- Attack Its Weak Point: Literally; they grow back their limbs/head and their torso is armor-plated. Only attacking the swollen white organ-sacks sprouting from their shoulders and chest will kill them.
- Big Creepy-Crawlies: Cockroaches mutated into a bipedal, man-sized format.
- Blade Below the Shoulder: Of the "blade for a hand" variety. Each arm is serrated scythe-blade.
- Creepy Cockroach: And that would be an Understatement for such a lethal creature.
- Death of a Thousand Cuts: It will take a lot of damage, but, if you continually blow off their head and arms, they will eventually die from the strain of growing them back. On the other hand, they can deliver this to you should they grabbed you.
- From Nobody to Nightmare: As said, these things used to be cockroaches. You know, the creepy-crawly bugs that run away and hide when you flick the lights on? Now, they're some of the most lethal killing machines in the Resident Evil universe.
- Glass Cannon: They actually can't take that much damage before dying... but, they will end you if you're not careful.
- Healing Factor: They can regenerate their head and arms, which is why you gotta aim for their organ sacks.
- Multi-Armed and Dangerous: They have four arms, all of them giant reaping sickle-claws.
- One-Hit Kill: Their primary attack, if they have all four limbs, is to grab you and them disembowel you.