This page is for characters introduced in ''VideoGame/ResidentEvil5'' only. For characters in other games or films in the game continuity, go to their respective debut media.

* ''Characters/ResidentEvil1''[[labelnote:Introducing]]Chris Redfield, Jill Valentine, Barry Burton, Rebecca Chambers, Brad Vickers, Richard Aiken, Enrico Marini, Albert Wesker, Lisa Trevor[[/labelnote]]
* ''Characters/ResidentEvil2''[[labelnote:Introducing]]Leon Scott Kennedy, Claire Redfield, Ada Wong, Sherry Birkin, William Birkin, Annette Birkin, Brian Irons, Marvin Branagh, HUNK, T-00 (Mr. X), Tofu[[/labelnote]]
* ''Characters/ResidentEvil3Nemesis''[[labelnote:Introducing]]Carlos Oliviera, Nemesis T-Type (T-02), Nikolai Ginovaef[[/labelnote]]
* ''Characters/ResidentEvilGunSurvivor'' [[labelnote:Introducing]] Ark Thompson, Lott and Lilly Klein, Vincent Goldman, Andy Holland, Bruce McGivern, Fongling, and Morpheus D. Duvall[[/labelnote]]
* ''Characters/ResidentEvilCodeVeronica''[[labelnote:Introducing]]Steve Burnside, Albert Ashford, Alexia Ashford[[/labelnote]]
* ''Characters/ResidentEvil0''[[labelnote:Introducing]]Billy Coen, Dr. James Marcus[[/labelnote]]
* ''Characters/ResidentEvilOutbreak''[[labelnote:Introducing]]Kevin Ryman, Alyssa Ashcroft, Cindy Lennox, Mark Wilkins, David King, Jim Chapman, George Hamilton, Yoko Suzuki, Linda, Carter, Monica, Rita, Regan Mallet[[/labelnote]]
* ''Characters/ResidentEvil4''[[labelnote:Introducing]]Luis Sera, Ashley Graham, Ingrid Hunnigan, The Merchant, Osmund Saddler, Ramon Salazar, Jack Krauser, Bitores Mendez[[/labelnote]]
* ''Characters/ResidentEvilTheUmbrellaChronicles''[[labelnote:Introducing]]Colonel Sergei Vladimir, The Red Queen[[/labelnote]]
* ''Characters/ResidentEvilDegeneration''[[labelnote:Introducing]]Senator Ron Davis, Angela Miller, Curtis Miller, Frederic Downing[[/labelnote]]
* ''Characters/ResidentEvilTheDarksideChronicles''[[labelnote:Introducing]]Manuela Hidalgo[[/labelnote]]
* ''Characters/ResidentEvilRevelations''[[labelnote:Introducing]]Parker Luciani, Jessica Sherawat, Raymond Vester, Clive R. O'Brian, Quint Cetcham, Keith Lumley, Rachael, Morgan Lansdale, Jack Norman[[/labelnote]]
* ''Characters/ResidentEvilOperationRaccoonCity''[[labelnote:Introducing]]Vector, Spectre, Beltway, Bertha, Four-Eyes, Lupo, Umbrella Security Service Command, Crispin Jettingham (Callsign: DEE-AY), Erez Morris (Callsign: HARLEY), Lawrence Kimbala (Callsign: SHONA), Marisa Ronson (Callsign: TWEED), Carolyn Floyd (Callsign: WILLOW), Sienna Fowler (Callsign: PARTY GIRL), Government Spec Ops Command[[/labelnote]]
* ''Characters/ResidentEvil6''[[labelnote:Introducing]]Jake Muller, Helena Harper, Piers Nivans, Carla Radames, Derek Clifford Simmons, Ustanak, Haos, Agent, President Adam Benford[[/labelnote]]
* ''Characters/ResidentEvilDamnation''[[labelnote:Introducing]]Svetlana Belikova, "Buddy"/Alexander "Sasha" Kozachenko, JD[[/labelnote]]
* ''Characters/ResidentEvilRevelations2''[[labelnote:Introducing]]Moira Burton, Natalia Korda, Gina Foley, Neil Fisher, Pedro Fernandez, Gabriel Chavez, [[spoiler:Alex Wesker]][[/labelnote]]


[[folder: Sheva Alomar]]
->'''Voiced by:''' Karen Dyer

->''"Don't worry. I may not be as big as you, but I can still hold my own!"''

Chris' partner during ''5'', with whom he develops a strong bond. She joined the BSAA to fight against biological weapons since her parents had been victims of experiments carried out in Africa with said weapons.
* ActionGirl
* BadassNormal
* BilingualBonus: Her tattoo reads "Shujaa," which is Swahili for "Hero."
* ButNotTooBlack
* TheChick: For her team.
--> '''Josh:''' Sheva became the little sister of the team.
* ColourCodedCharacters: [[WordOfGod Production notes]] state that it took the team a while before deciding on her signature color -- lavender.
* FurBikini: One of her alternate costume.
* GoodIsNotSoft: Even amongst the other player characters, Sheva stands out. She is one of the nicest characters in the series, especially if you build up her trust, established to be just as good as Chris, Jill, Leon, or Claire, and in the final boss fight, you can have her do one of the most BadAss things in the series and turn Wesker's chest into a scratching post.
* HeroicSacrifice: [[spoiler:She was about to perform one, but Chris saved her from herself.]]
* KnifeNut: Sheva will straight-up shank a fool if given the opportunity.
** Including [[spoiler:Wesker. While he's infected with Uroboros.]]
* MaleGaze: The first thing you're shown of her is pretty much her ''ass''. Lampshaded by {{Unskippable}}.
* NoCelebritiesWereHarmed: Her "Clubbin'" alternate costume is visibly inspired by a similar outfit worn by Halle Berry in ''Swordfish''.
* TheLancer: For Chris.
--> '''Sheva:''' There's only so much one person can do. Even a superhero like you, Chris.
* Literature/LittleRedRidingHood: One of her alternate costumes is a HotterAndSexier version of the fairy tale (for [[FetishFuel some reason]]).
* ShoutOut: One of her alternate costumes is a throwback to Hunnigan from ''4''.
* SexySecretary: One of her alternate costumes is of a SexySecretary with a BadassInANiceSuit vibe.
* StepfordSmiler: She outrightly defies this trope based on analysis. Despite her tragic background, she refuses to be a [[EmptyShell let down]], and instead keeps a [[ThePollyanna healthy and upbeat attitude]]. Most characters in her position are usually TheStoic, TheWoobie, etc. If you just met her and didn't know her, you would think her life was [[TastesLikeDiabetes sunshine and rainbows]].
* TrueCompanions: She's pretty much about this, either for Chris or for her team.
* WhatTheHellIsThatAccent: She's supposed to be a native African, but her accent is rather inconsistent, and you'd be forgiven for thinking she's British.

[[folder: Josh Stone]]
->'''Voiced by:''' T.J. Storm

The captain of BSAA West Africa Branch and Sheva's mentor. He becomes Jill's partner in DLC, Desperate Escape.
* {{Badass}}: Firmly establishes himself as one, both as Jill's parter in ''Desperate Escape'' and in the Mercenaries game, where he's lugging the shotgun and an RPG.
** Not to mention using hammer punches and elbow drops.
* BlackDudeDiesFirst: Averted. [[spoiler:He survives the entirety of ''[=RE5=]''.]]
* TheGoodCaptain: Of BSAA West Africa.
* LowerDeckEpisode: A DLC campaign ("Desperate Escape") in ''VideoGame/ResidentEvil5'' allows you to play as him and Jill Valentine trying to escape from the Tricell headquarters.
* TheMentor: To Sheva.
* WrestlerInAllOfUs: His melee takedowns include elbow drops, German suplexes, and ''chokeslams''.

[[folder: Ozwell E. Spencer]]
->'''Voiced by:''' Adam D. Clarke

A British [[BlueBlood lord]] and one of the three founders along with Dr. James Marcus, and Edward Ashford also is the President of the Umbrella Corporation, who set in motion the events of the entire series in an attempt to make a new, superior race with himself ruling over it.
* AGodAmI: Or so he dreamed. "I was to become a god!"
* AristocratsAreEvil: He's a Lord......his last name is perhaps a ShoutOut to the venerable Spencer family, of which Princess Diana was a member.
* BadBoss: In [[DownloadableContent "Lost in Nightmares"]] from ''VideoGame/ResidentEvil5'', you can read diary entries of those who worked in Spencer's mansions. It seems he turned a lot of them into test subjects, and ultimately into monsters and zombies.
* TheChessmaster
* CelebrityResemblance: His voice actor, who is a self-admitted ''Franchise/StarWars'' fan, based his voice on that of Ian [=McDiarmid=]'s role of Emperor Palpatine, with Spencer himself being modeled after the man.
* ChronicBackstabbingDisorder: Kills Marcus through Wesker and Birkin, betrays the latter for attempting to leave Umbrella, betrays George Trevor by locking him inside his mansion, and lastly betrays [[spoiler:Wesker by admitting he is his creation]].
* CorruptCorporateExecutive
* [[spoiler:CutsceneBoss]]: After waiting numerous games to meet Ozwell E. Spencer in the flesh, [[spoiler:Wesker kills him in a cutscene. Although, fighting an 89 year old man on life support probably would not have been an epic boss battle.]]
* DarkLordOnLifeSupport: The years have clearly taken their toll. He was even the page image for a time. He's reduced to being confined to a wheelchair and life support system three years before ''VideoGame/ResidentEvil5'' due to his old age. [[spoiler:He expects Alex Wesker to reverse this condition by engineering an Immortality virus, although Albert Wesker kills him to become the BigBad after Spencer reveals that Wesker was one of many {{Unwitting Pawn}}s for Umbrella known as "Wesker children" in a project done to create the perfect breed of humans.]]
* EvilCripple: He's in a wheelchair when Wesker finds him.
* EvilOldFolks: 89 [[spoiler:when he dies.]]
* GreaterScopeVillain: He's TheManBehindTheMan to all of Umbrella, including [[AGodAmI Alexia]], [[DragonInChief Sergei]], [[MadScientist Birkin]], and the series' most recurring villain, [[ChronicBackstabbingDisorder Albert Wesker]]. Yet, he is rarely seen throughout the series and doesn't even interact with the protagonists.
* [[spoiler:ImpaledWithExtremePrejudice: How Wesker kills him, using his bare hands!]]
* MadScientist
* TheManBehindTheCurtain: He's behind all the bad stuff in the series, whether directly or indirectly, but he's little more than a pitiful old man, whining about how he was unable to achieve godhood.
* TheManBehindTheMan: To Sergei, who's his DragonInChief, Alexia, and Birkin (who he employs), and in an odd way, Wesker, who he created.
* MeaningfulName: He shares a last name with Herbert Spencer, the philosopher who conceived Social Darwinism.
* NiceJobFixingItVillain: If Spencer didn't order Wesker and Birkin to assassinate Dr. Marcus, none of the events relating to Umbrella's downfall and afterwards would have happened.
* NonActionBigBad: Par excellence.
* SmugSnake: Smart and a capable schemer, he's behind almost every bad thing in-series, but he waited too long to put his plan in motion, allowing Wesker to hijack it for himself.
* [[spoiler:TheUnfought: The heroes never even meet him alive. He's already been killed by the time Chris and Jill bust into his chamber.]]

[[folder: Excella Gionne]]
->'''Voiced by:''' Nina Fahren

->''"You're just not ready for me!"''

Excella is the CEO of [[MegaCorp Tricell]] Africa and one of the people responsible for the creation of the Uroboros Virus. She also shares Wesker's idea of WorldDomination and intends to be the [[GodSaveUsFromTheQueen Queen]] of the new world with Wesker as her King.
* AbsoluteCleavage: See the image.
* AllGirlsWantBadBoys: She was in love with Wesker of all people!
* ArmorPiercingSlap: Has the literal version in ''Mercenaries Reunion''. And yes, her slaps can make enemies' heads explode.
* TheBaroness
* BetterLivingThroughEvil
* BrainyBrunette: Evil Brainy Brunette.
* CombatStilettos: She keeps her high heels in Mercenaries Reunion.
* {{Dark|ActionGirl}} LadyOfWar: Though she doesn't fight in the actual game, on Mercenaries Reunion, she kicks ass with vicious elegance.
* TheDragon: To Wesker.
* EtTuBrute: [[spoiler:On the receiving end of this, though seeing this is Wesker we're talking about, it's really no surprise.]]
* EveryoneLooksSexierIfFrench: Sort of. She possesses a French Accent, but her last name is closer to that of Italian.
* EverythingSoundsSexierInFrench
* EvilutionaryBiologist
* FemmeFatale: {{Subverted}}. She has all it takes to be one fierce Femme Fatale -- beauty, intelligence, and cunning -- but [[spoiler:she is the one who falls for Wesker's [[TheCasanova masculine wiles]] and pays for it.]]
* HotScientist: She majored in genetic engineering.
* JigglePhysics
* MsFanservice
* OmnicidalManiac: Excella agrees with Wesker's plan in ''VideoGame/ResidentEvil5'', which would include killing, at the least, ''billions'' of humans.
* RichBitch
* SayMyName: '''ALBEEEEEERRRT!!!'''
* SexyBacklessOutfit
* SheFu: Her Disco Spin move.
* StatuesqueStunner: 5'9".
* {{Stripperific}}: A backless mini-dress and pumps is not the appropriate attire for running around the African jungle or an oil rig.
* [[spoiler:TooDumbToLive: It's hard to believe she really thought Wesker ''wasn't'' going to stab her in the ribs.]]
* UnholyMatrimony: With Wesker, though they weren't indeed married to each other but in her head...
* WomanInWhite: Though it's not played for mystery or necessarily to show that she is evil.
* WomanOfWealthAndTaste: Her dress and shoes are both based on pieces by real life haute-couture designers. [[EverythingsSparklyWithJewelry Her jewels look just as expensive and chic]].

[[folder: Ricardo Irving]]
->'''Voiced by:''' Allan Groves

Director of the oil facility headed by [[MegaCorp Tricell]] Africa, Irving helped found its B.O.W. research department, and subsequently became known as a "death dealer" on the black market for distributing the products Tricell developed to African bioterrorists. Chris and Sheva going to Africa to capture him is what kickstarts the events of ''VideoGame/ResidentEvil5''.
* DefiantToTheEnd: Upon his death, he keeps laughing and mocking Chris and Sheva:
-->'''Irving''': "Dying's not so bad. But it doesn't change anything... '''you're still screwed!'''" (''cue EvilLaugh'')
* DiscOneFinalBoss: The first part of the game is all about chasing him, investigating him, and arresting him -- it's only upon his defeat that he lets it slip he was merely following orders from Tricell's CEO, Excella.
* ItsAllAboutMe
* LargeHam: Especially once he goes OneWingedAngel.
--> '''Irving:''' I've given myself an extreme makeover!
* OneWingedAngel: A gigantic sea-beast most comparable to [[KrakenAndLeviathan The Kraken]].
* ScrewThisImOuttaHere: Attempted this after failing to kill Chris and Sheva. It didn't work out for him.
* WhatTheHellIsThatAccent: His accent sounds either [[BrooklynRage Brooklyn]] or New Jersey.
* YouHaveOutlivedYourUsefulness: By being forced to infect himself with a dominant-strain of Plaga.

[[folder: Alex Wesker]]
-->"You'll be pleased to hear that all experiments are running smoothly."

Mentioned by files in VideoGame/ResidentEvil5's 'Lost in Nightmares' DLC.

For the tropes pertaining to this character, and be warned '''there will be spoilers''', see [[spoiler:Characters/ResidentEvilRevelations2]].