Alexa Lexington
Annie Radd
Barney Cull
Beebee
A girl who thinks she's the queen of the bunny people. In
Agents, she's dating the heir to a water bottle empire
that turns out to be a villain.
Brandi
One of Morcubus's assistants in
Agents.
Buddy
Originally works as a bellhop in the local hotel. In
Agents,
he is the main character's partner.Zombie Carl
Chaz Mc Freely
Extreme stuntman.
Daryl Handsly
A magician. In
Party, he runs the Surprise Event, which can award Sims with items or alter their stats for the rest of the tournament.
Derek
Dolly Dearheart
Clothing saleslady.
DJ Candy Supergroove
A D.J. In
Agents, she's an important character in two of the main cases, and a dispatch mission requires you to help her set up a concert on the moon.
Dr. F
Elmira Clamp
- Scary Librarian: Elmira Clamp. Good God, Elmira Clamp.
- Even when she's not a librarian. *shudder*
Esma
Morcubus's assistant in
Agents along with Yuki and Brandi.
Evelyn
 | In Agents, she is one of the main characters, who helps the player and Buddy search for the Nightmare Crown that her father worked on. |
Gertrude Spackle
A girl who likes bugs.
Gabriel
Ginny
- Fiery Redhead
- Pirate Girl: "Cap'n" Ginny is obsessed with pretending to be a pirate.
- Though she seems to change occupations with each game.
Gino Delicioso
A chef. In
Agents, his pizzeria is your main character's original base of operations, and you later have to help him find a map thief.
Goth Boy
 | A boy that writes depressing poetry as a hobby. In Agents, he sells turkey on a stick at the beach area. |
Hisao Watanabe
A sushi chef.
Hopper
A boy in a frog costume.
Jenny
Jimmy Watanabe
The lazy son of Chef Watanabe.
Justice
In
Agents, he runs a tattoo parlor. In
Sky Heroes, he is the leader of
La Résistance that rescues the main character in the beginning.
Leaf
 | A millennia-old elven rockstar, first appearing in MySims Kingdom. |
Liberty
Luke
Lyndsay
Makoto
- Blush Sticker: The regular Makoto.
- Deceptively Human Robots: On the surface she looks like a rather ordinary (if overly happy) schoolgirl. Talk to her, though, and you'll see that speaks in ALL CAPS and constantly reasserts that she is "A HUMAN, LIKE YOU, NOT A ROBOT". Through talking to her you eventually discover that she was built by Dr. F, who she calls "father".
- Robot Girl: The point of her existence. She goes to high school and even asks for help in MySims Agents to get her yearbook signed and to become Prom Queen, trying to achieve "popular status".
- Super-Powered Robot Meter Maids: Well, considering how she was built by Dr. F, it is obvious that she has Super Strength and probably has all manner of other secret gadgets.
- What Could Have Been: Both forms of Makoto- regular and Proto-Makoto- were planned to appear in MySims Agents! Sadly, Proto-Makoto was cut from the game for unknown reasons, but the original remains in the Industrial District. What could happen if the two were ever in the same game and met? For now, all relegated to Fan Fiction.
Maria
- Big Eater: While most of the Sims who have Tasty as their favorite interest are like this. Maria is probably the best example. "When's the celebratory feast? After dinner?"
Matt
Television show host.
MC Emi
The host of
Party, the only game she has appeared in.
Mitch
A monkey that works as MC Emi's assistant.
Morcubus
Ms. Nicole Vogue
Fashion Designer.
Patrick Rhino
A truck driver. He is a construction worker in
Agents.
Paul Wisnewski
The yeti of the mountains, accused of kidnapping Beebee's boyfriend Preston, and later, destroying the lounge.
He did neither.Petal
Pinky
Loves the colour Blue.
Poppy
Violet's younger sister. Usually seen running her own flower shop.
Preston Winthrop Esquire
Professor Nova
Ray
Renée
A girl that raises pigs.
Rhonda
Good-natured; she is a girl with a different motto everyday and stays out of trouble.
Rob Jarrett
Video game nerd.
Rosalyn P. Marshall
In the original title and
Party, she is the mayor of the city your character moves into, whereas in
Kingdom she is the High School Principal of the Royal Academy. In
Agents, she is a non-Special Agent that works alongside Vic.
- Agent Scully: In Agents.
- Fantastic Racism: But once she discovers the paranormal do exist, she's utterly convinced the crime is their doing.
- Nervous Wreck: As the headteacher of the Royal Academy.
Roxie Road
An ice cream salesperson who loves Bees. In addition to dressing like one, her shop is shaped like a giant beehive. In
Agents she works for the player and runs forensic analysis as needed.
Samurai Bob
Shirley Vogue
A hairstylist, Nicole's sister.
Star
Summer
Tim
Travis
- Big Man on Campus: In Kingdom.
- Chaste Hero: In Kingdom, both of the female characters in The Royal Academy are in love with him and want him to take them to the Prom. Instead, he is more interested in his phone, which doesn't amuse either girl very much.
- Green Lantern Ring: His telephone's apps can mimic animal calls, order pizzas, act like a glowstick, has beverage frothing capability...
- Oblivious to Love: He doesn't really catch on that the girls have their eyes on him.
Trevor Verily
A Shakespearian actor.
- Wholesome Crossdresser: During his play in Kingdom, he has no problem dressing for and playing the role of the princess - even if the Player is a girl.
T.O.B.O.R.
One of Dr. F's creations.
Vic Vector
Manager of a video game store. In
Kingdom, he is originally a janitor, but Dr. F convinces him to temporarily work as an astronaut. In
Agents, he works with Rosalyn to solve a crime involving Yetis.
Violet Nightshade
Poppy's big sister.
Sir Vincent Skullfinder
A treasure hunter. And by 'hunter', we mean 'gets other people to hunt for him'.
Yuki
 | A girl that's interested in biting people's faces. |