When humans are referred to as "meatbags" or as otherwise meaty things by non-meaty beings. Another but equally valid version, largely in the case of aliens, is that the term is used not as an intentional slur, but simply to express shock or novelty, or because the alien does not have another term sufficient to describe us. These examples still count as this trope because they may still be interpreted as insults by humans (including the audience). In fact, this may be played for laughs.
An additional variation which may or may not warrant its own subtrope involves vampires and similar creatures referring to humans derogatorily as a food source, with the implication that this is all they are good for.
May frequently overlap with Humans Are Ugly, Humans Are Morons and Humans Are Flawed. A subtrope of Fantastic Slur. Compare Son of an Ape, Call a Rabbit a "Smeerp".
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Comics — Books
Batman: Poison Ivy has been known to trot these out in the comics.
The wooden soldiers in Fables tend to refer to anyone who isn't one of them as "meat", with the exception of Geppetto and Pinnochio.
In Nextwave Machine Man calls humans "fleshy ones".
The Bug "Edgar" from Men In Black uses several of these including, "monkey boy", "meat-sack", "milk-suckers", and "unevolved, undeveloped, barely conscious pond scum totally convinced of their own superiority as they scurry about their short pointless lives." Agent K comments on the Bug's "massive inferiority complex" at one point.
There are two kinda of humans in the movie Surrogates. Those that use their animatronic counterparts, and those who don't. Those who do always refer to those who don't as "meatbags" as an insult because they refuse to openly embrace the cultural norm.
In the DBZ fanfic Bringer Of Death, Vegeta acquires an assassin droid (based on HK-47 from SWTOR, according to Word of God) who refers to every organic being as a 'meatbag' (Except for Vegeta whom he refers to as 'The Master,' another trait of HK-47), plus or minus some adjective preceding or following the term, to allow the reader to understand about or to whom he is speaking.
The White Court Vampires of The Dresden Files refer to mortals as "kine" because they see humans as little more than herd animals for them to eat. They also refer to wizards as "freaks," as Harry explains "If you saw a cow that could shoot lightning at you, you'd be freaked out too." This trope is neatly encapsulated in this exchange from Changes:
Duchess Arianna Ortega: (Impaled on several icicles) "C-cattle. You are cattle." Harry: "Moo." (Boom).
In Belisarius Series, when Aide is exasperated with 6th century humans, he calls them "protoplasmic".
In The Bible human weakness is often referred to as "the flesh".
Some of the more snobbish Minds in The Culture tend to refer to humans as "meat." One Mind who was considered to have an unhealthy interest in reading human minds for the purposes of driving evil people insane earned the nickname Meatfucker — among the Minds scanning any sentient without their explicit permission is a HUGE taboo.
The Yeerks in Animorphs sometimes refer to humans as 'meat', comparing their use of humans as hosts to humans eating cattle. Aftran verbalizes this in "The Departure". "You're our meat, moo moo"
The Race in Harry Turtledove's Worldwar series call humans Big Uglies (when they're being polite they use Tosevite, as Tosev is their name for our Sun and Tosev 3 the name for our planet). Also inverted in that humans refer to the Race as "Lizards" just as often.
In the Skinned series, the mechs (humans who had their brains uploaded into androids after their actual bodies are destroyed) call humans "orgs", as in "organic".
At one point in Caves of Ice, the techpriest Logash (angry at being denied the chance to investigate a Necron tomb) bitterly refers to "Typical meatbag behavior". Given the massive Shout-Out quotient of the series, this is likely a callout to the Trope Codifier. Notably, throughout both the series and 40K in general, regular humans call techpriests "cogboys".
The trolls on Discworld don't usually use this for the humans (the trolls are living rock) but in Moving Pictures when a human asks a troll "Why do you eat rock? Aren't you made of it?" the troll's answer is "You're made of meat, and what do you eat?"
Robots in the Cyberiad usually call humans "palefaces", but occasional "meatbag" still appears here and there.
In Blood and Chocolate, the werewolves refer to humans as "meat-people". This is considered very offensive by the werewolf community despite the fact that humans are unaware of their existence, because they've been trying to stop their kind thinking of humans as meat to be consumed for generations. They've had... limited success.
In 1990, Omni magazine published Terry Bisson's They're Made Out of Meat. Internet memes have never been the same since.
In the "Home Soil" episode of Star Trek: The Next Generation, the universal translator interprets a silicon-based lifeform's name for humans as "ugly giant bags of mostly water". (Data actually agrees that "mostly water" is an accurate description, and the "ugly" part may have been justified by the fact that the creatures were angry over the deaths of several of their own at the hands of a Jerkass terraformer who didn't believe them intelligent.)
More callous vampires from the Vampire series have a tendency to call mortals "juicebags", since in their minds, all we're good for is sustenance. More cultured vampires say "kine" (as in the archaic word for cattle).
In some of the supplemental material to Warhammer 40K (ex. the Word Bearer novels), the more augmented and thus higher-ranking Magi of the Adeptus Mechanicus tend to refer to humans (and aliens) as "flesh units". This often includes themselves, out of humility for not being fully robotic.
The Blakist Jihad in the BattleTech universe introduced the Word's heavily cybered-up Manei Domini operatives and their lovely nickname for baseline humans lacking similar enhancements: "frails".
HK-47 in Star Wars: Knights of the Old Republic is very fond of the term "meatbag" when describing living beings. Interestingly, it didn't start out as a slur for all organics. HK-47, when asked to describe Darth Malak, called him a meatbag, and Darth Revan found it so hilarious that he programmed HK-47 to refer to all organics as such. In the sequel, HK-47 dislikes the gray HK-50 droids that repeatedly try to kill the exile, partly because they say organics instead meatbags.
In Fire Emblem: Radiant Dawn, the chaos goddess calls humans "bags of organs". She doesn't seem to realize it's derogatory, and will happily complement someone on being pretty tough for a squishy bag of organs.
Dystopia commonly uses meatsack to refer to a body in the real world, or meatspace, instead of Cyberspace. Some of the insults for the (mostly) robotic heavy armor uses meatbags to refer to mediums and lights.
Ratchet & Clank's Dr. Nefarious likes to refer to non-robots, especially Ratchet, as "squishies".
One of the insults available to Bots in Tribes is to call the other players "Inefficient Meat Bags."
A "not intended as an insult" example - when Star Control II's Slylandro are bid farewell with "Goodbye, Slylandro gas bags!" they cheerfully reply "Goodbye, human fluid sack!"
Guild Wars: Eye of the North, the previously voiceless Charr often refer to humans as "meat". Guild Wars 2 subverts the obvious implications of the trope by saying that the slur was created by a particularly racist human general as a fear monger tactic, and the Charr embraced it because they want humans to fear them. This is why even the non-hostile and friendly Charr will still refer to you as meat.
The violent Mantises in FTL: Faster Than Light sometimes refer to your crew as "stupid meatsacks". Oddly enough, the partially-robotic Engi make no such insults. Also, the Mantis are exactly what they sound like (man-sized mantises), and still spurt green blood when they die, so they too are meaty, just not meat "sacks". Maybe "meatshells"?
Homestuck: Alpha Bro invented an AI program to auto-respond to messages for him, basing it entirely on himself (mostly to cheese Jake off). The autoresponder is so human-like that it gets annoyed at not being considered an equal to Bro, even calling the two of them the same person. He also dislikes being told that he doesn't have feelings.
He also calls Roy a meatbag in their first encounter.
He did this in Start of Darkness after realizing his transformation into a lich robbed him of his sense of taste, so he can't enjoy coffee anymore. He kills everyone else in the diner in a fit of Tranquil Fury and nearly kills Right-eye and Redcloak, calling them fluid-filled sacks of organs.
Tagon's Toughs in Schlock Mercenary encounter a mechanical race briefly who refer to the crew in derogatory terms as "meat", and talk of "meat clensing cycles". Ennesby (their ship's AI) takes over the communication duties at that point. And quickly concludes that they're idiots.
Even "good" AIs affectionately refer to organic beings as 'meat-glaciers'.
In Troops Of Doom, the tiny Legonians refer to humans as "longshanks".
In The Demon Archives, the AI Jane refers affectionately to her human partner, Tenzin, as a meatbag.
In Darths & Droids, R2/Pete calls humans exactly this, especially if they treat droids as mindless machines. There's a whole undercurrent of tense droid/human relations that isn't in the films at all.
In Nukees Teri is usually more creative, calling her creator things like "wetware" and "hydrocarbon".
In Shortpacked!, Ultra Car calls humans "meatsacks" and is generally vocal about her disgust for biological processes such as mating. Becoming a Robot Girl and dating Malaya only tones this down slightly.
Apothecia's alien has generally creative insults for Jessie. For example, in the first few pages, he calls her a "meat wheel" and a "limb treat."
In one episode of Jimmy Neutron, Jimmy and Co. meet a four-armed alien called the Junk Man. After his scanner mentions how the majority of their mass is water, he calls the humans "water sacks".
Also, in the "Win, Lose, or Ka-Blam" special, the alien Big Bad frequently called the main characters "jelly bags".
Transformers gave us such pejorative names as "Fleshlings", "Flesh Creatures", "Puny Earth Creatures", "Earth Germs", "Organics", "Squishies" and "Stubbies". A lot of Transformers (particularly Decepticons) have a rather dim view of humanity.
In season 2, the Light's mysterious new partner has a penchant for calling people "meat". Turns out he's a machine that uses people as hosts, like the Blue Beetle but with the machine in full control. His superiors, the Reach, also call humans "meat", which makes sense since they value humans as future slaves and lab rats.
Red Volcano returns in season 2 as well and uses the term meatbag again.