Normally when people play Slender, they are nervous playing and freak out and runaway from the first sight of Slenderman. Matt though, he takes everything this game can throw at him with no fear at all. Heck, he even calls out Slenderman to come out and charges at him when he finally does. Albeit this ends in Matt's death, but still.
For the greater part of Erie, Pat skillfully avoids the horrific monster chasing him with no foreknowledge thanks to his and Matt's quick thinking, only ever getting caught three times, once because they didn't even know the monster existed, and once because the monster got stuck on a wall. At several points he stops to actively taunt the monster and gets away with it.
In the bloopers segment for Metal Wolf Chaos, Matt somehow starts off on a tangent about if The Hulk was the president and fought terrorism in a giant hulk-bot built by Tony Stark. Pat spends a few minutes arguing how over-the-top stupid it is, before breaking down and admitting it's awesome.
In fact, the entire idea of the Anarchy Reigns Brawl. Consider how much more work went into the video than they usually do: they had to haul in three 360s, three TVs, set up their recording, and then hack together the footage from three separate feeds in order to make a cohesive video. Just shows how much they love the game.
Not only that, but when he gets to Monsoon, he not only beats him on the first try, but he got a S rank on the fight!
The entirety of the Jetstream Sam playthrough. Some highlights include taunting a Metal Gear Ray, killing enemies in single hits with Sam's charge attacks, and Pat managing to not only taunt Armstrong into a blind rage, but dodging every attack thrown at him in Armstrong's enraged state.
Pat also happens to lower Armstrong to Quick-Time-Event health right as he uses his giant fire pillar move, which makes it so that giant pillars of fire are exploding in the background while the quick-time event is playing.
Bladewolfs DLC has a good moment near the end of the last level where Pat Zandatsu's a Sword Mook while simultaneously slo-mo dodging a rocket from another mook. While the instrumental of "I'm My Own Master Now" plays in the background.
At E3 2013, Pat plays the Bayonetta 2 demo for the first time and ranks gold.
During Part 4 of The Last of Us Pat manages to defeat four runners and a clicker without dying or being detected once. Even better he didn't have to use any of his weapons, he just snuck up on all of them one by one and choked them from behind.
Woolie's Badass Boast after defeating Nathan Copeland in No More Heroes 2.
During their Deadly Premonition playthrough, Pat is consistently taunted by his nemesis, Quint, and get's more and more infuriated when he can't track the man down. Finally, Pat catches up with the mad genius and proceeds to wreck the shit out of his life by ending Quint's engagement.
Matt's snake Jack making his feelings on the Super Best Friends Podcast known by actually flicking his tongue out at the end of the promo video, prompting 'that was awesome' reactions from both Matt and Woolie.
Pat winning the Scrublords grand finale. He won at the only game that truly mattered: Divekick. Made even better by the fact Woolie took the first round 5-0.
Woolie stepping up and pulling the Indigo Prophecy playthrough out of its funk by being a serious hype-man during the ridiculous room assault section.
With Beyond: Two Souls, how they're actually giving the game a chance and actually appreciate some elements. Lots of the fanbase has accused them of not doing so, but actually watching the videos, they are trying - the game is just proving more ridiculous and terrible than they imagined.
And after viewing the credits and seeing how it was different from the ending they got, and learning that the ending they got doesn't even matter Woolie goes on another speech calling Cage out, on essentially mooting all choices they have done throughout the game, this time the speech is backed up by Pat and Matt.
In Penumbra: Overture, the standard (and game-recommended) way of dealing with the wolf enemies is hiding from them. Upon seeing one for the first time, Pat immediately hits it with a hammer and knocks it over.
Part 12 of Pat and Woolie's "I Have No Mouth and I Must Scream" LP. For most of it, Pat had been going by the strategy of carefully examining everything in the environment before making his decision or taking any action. Then he comes up against a Nazi scientist about to remove the spinal chord of a child. He looks around the room a little and upon finding a scapel, immediately goes to stab the scientist with it. Even Woolie wasn't expecting that. After a guard kills Pat for it and the sequence starts over again, he just does the same thing again and finds a way to get away with it.
Can we get some love for all of the Funtime Adventures? All five episodes are amazingly animated, continually funny and always feature at least one awesome sequence. Episode 5 is the pinnacle of it, with Pat falling out a tower, killing a ton of enemies on the way down to use them as a crash mat for his landing.