List of actors and actresses who appeared in Spenser related media.
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Television
Spenser: For Hire
Appeared in Spenser For Hire (1985-1987):
- Trini Alvarado: Laurie Kincaid
- Victor Argo: Hitman
- Gerry Bamman: William Reed/Laurence Denning
- Angela Bassett: Alice
- Patrick Breen: Bobby Olak
- Avery Brooks: Hawk
- David Allen Brooks: Dr. Ed Howard
- Kate Burton: Randy Lofficier
- J. Kenneth Campbell: Deputy Hagen
- Ron Canada: Stapleton
- Timothy Carhart: Georgie Harley/Jim Gullen
- Patricia Charbonneau: Linda Shannon
- George Cheung: Henchman
- Bill Cobbs: Larry Sills
- Kevin Conroy: Gallagher
- John Cullum: Anthony Bennett
- Michael Currie: Sheriff Bayer
- Cleavant Derricks: Mac Dickerson
- George DiCenzo: Dan Chandler
- Badja Djola: Tyrone Blackwell.
- Paul Dooley: Bryce Taylor
- James Eckhouse: Lt. Cmdr. Carl Westmore/Robert Jordan
- John Finn: Ken Green/Monroe
- John Fiore: Frankie Almeida/Bodyguard
- Laurence Fishburne: David Mukende
- Richard Gant: George
- Barbara Garrick: Valentine/Cathy Lowington
- Erica Gimpel: Shelley
- Seth Green: Andy Chandler
- David Groh: Tony Romano
- Paul Guilfoyle: Ross Bates
- Stan in A Man Called Hawk
- Tim Guinee: Kevin Moran
- Mitchell O'Connor in A Man Called Hawk
- Jack Gwaltney: Champ/Charlie Horn
- James Handy: Joe Glenn
- Kadeem Hardison: Bobby Waters
- Anthony Heald: The Doorman
- Celeste Holm: Rose
- Brian Howe: Cab Driver
- Samuel L. Jackson: Leroy Clancy/Ned
- Erik King: Louis Harper
- Street Brother in A Man Called Hawk
- Shirley Knight: Katie Quirk
- Thomas Kopache: Grady
- Kasi Lemmons: Lydia Wilson
- Lois in A Man Called Hawk
- Melissa Leo: Mary Hamilton
- Geoffrey Lewis: Harry Patterson
- John Bedford Lloyd: Powers' Thug/Keith Kincaid
- Michael Lombard: Lucas Cantrell
- Andie MacDowell: Maggie
- Bruce MacVittie: Ronny Horgan
- William H. Macy: Efrem Connors/District Attorney
- Mako: Tommy Nguyen
- Nancy Marchand: Emily Garden
- David Margulies: Karl Shore/Lou De Franco
- E. G. Marshall: Judge Jason Kingsley
- Carolyn McCormick: A.D.A. Rita Fiore
- John C. McGinley: K.C.
- Rob Morrow: Danny
- Ed O'Neill: Buddy Almeida
- Mike Nussbaum: Gelman
- Liann Pattison: Millie
- James Rebhorn: Father Hoyt/Paul Manning
- Ving Rhames: Henry Brown
- Larry Riley: Bo Braxton
- Janice Rule: Mrs. Bennett
- Deborah Rush: Angela
- Jay O. Sanders: Father Crawford
- Officer Brogan in A Man Called Hawk
- Tony Shalhoub: Dr. Hambrecht
- Rocco Sisto: Eddy Duffy/Sonny Stroud
- Jimmy Smits: Hector Valdes
- Drew Snyder: Paul Martine
- John Spencer: Joe Moran
- Barbara Stock: Susan Silverman
- Robert Urich: Spenser
- Daniel von Bargen: Mr. Hurley/Al
- J. T. Walsh: Andrew Lawford
- Kenneth Welsh: Lt. Nicholas Webster/Webster Bloom
- Margaret Whitton: Janet Cole/Ellen Calone
- Trey Wilson: Jack Weller/Terry Vogel
A Man Called Hawk
Appeared in A Man Called Hawk (1989):
- Tatyana Ali: Michelle
- Steven Culp: Carter
- Moses Gunn: Old Man
- Janet Hubert: Serita
- James McDaniel: Ringer
- Peter McRobbie: Charlie
- Patrick O'Neal: Mr. Thorpe
- Maryann Plunkett: Susan
- LaTanya Richardson: Doris Gilbert
- Roger Robinson: Cy Ferris
- Kimberly Scott: Mary
- Tom Wright: Agent Tom Wilson
Films
Spenser: Small Vices
Appeared in Spenser: Small Vices (1999):
- Bill Lake: Police Captain
Spenser Confidential
Appeared in Spenser Confidential (2020):
- Alan Arkin: Henry Cimoli
- Winston Duke: Hawk
- James DuMont: Bentwood
- Michael Gaston: Captain John Boylan
- Post Malone: Squeeb
- Thomas Rosales Jr.: Marcelo
- Iliza Shlesinger: Cissy Davis
- Mark Wahlberg: Spenser
