Adam Warren's Livewires miniseries (technically done for Marvel Comics, but almost never mentioned since then) ends with a humdinger. Stem Cell, the team Woobie, is left running around free while her fellow robot secret agents have been captured by a hivemind army of Nick Fury robot duplicates. In desperation, she starts modifying her own programming (which required prying out her eyeball with a screwdriver to physically hack her own brain— and she had fully human pain senses and emotions at that point!) to find a way to save them. Later, she faces her enemies:
Stem Cell: This is Stem Cell, broadcasting loud and proud from your roof!
Hollowpoint Ninja: Stem Cell - No! Hide!
Stem Cell: You know, I'm considering changing that name. Stem Cell's a noob name... and I'm an ops virgin no longer.
Nick Fury Android Copy Groupmind: (with big evil grin) That's somethin'. Be kinda sucky if you was gonna die a virgin.
(strange noises start coming out of the ducts)
Stem Cell: Nossir, not a virgin of any sort. You want proof? YOU WANNA SEE MY BABIES?!
(And then her army of jerry-rigged fusion-powered nanotech monsters on fire come out of the ducts and kick the crap out of the Nick Furies)
- She then tops this by escaping a nigh-inescapable situation (the nanotech monsters having no 'off' switch). While leaving she gets in a parting shot: "My advice? Think of something insanely clever. I know I just did. Good luck, you eyepatch-wearing piece of hiveminded crap."