The entire climax is an escalating series of crowning moments:
- As all hell is breaking loose, the combined forces of a restored Kaine in Spidey's Sonic stealth suit, Agent Venom, the Avengers, the Future Foundation and all the major heroes battle it out with a giant spider monster version of the Queen while Spidey uses his smarts to commandeer Doc Ock's mini-robots from a previous story to administer a cure to every infected person (thus reducing the Queen's power) with a spider-powered Mary Jane fighting an army of infected to protect him. As he continues to cure the entire population, Peter laughs and declares that just this once, he's going to save everyone.
- Flash Thompson, the new Agent Venom, standing side-by-side with Steve Rogers himself as they start the final battle with the Queen.
Commander Rogers: You still with me soldier?
- Kaine, long hated for being the obligatory Nineties Anti-Hero part of The Clone Saga, uses his new Spidey suit to cancel out the Queen's sonic scream, and his new stingers to do what Peter Parker never would, and end the Queen's life when Peter manages to weaken her, while declaring to all wondering who he is that "I am Kaine!" And before Madame Web can claim that clearly he was the Spider-Man she foretold would save the world from this threat, Kaine states says everyone that he only could do it wearing a suit Spidey made, using a move Spidey perfected, at a moment that Spider-Man created for him. As far as Kaine is concerned, as well as everyone else, the one who is responsible for the Queen's defeat is the one and only Amazing Spider-Man. And that is how you rescue Kaine from Scrappy status.