- Acceptable Targets: Younger women, almost every one of whom is portrayed or referred to badly. And men, of course.
- Awesome Music: "You Don't Own Me".
- Billy Porter's version of "Love Is On The Way" is a beautiful and heartbreaking ballad available on the film's soundtrack.
- Designated Villain: Phoebe, Bill's mistress. Unlike the other mistresses, she didn't have any ill will towards Elise and genuinely idolized her, even coming to her career-resurrecting play to enthusiastically cheer her on.
- "Funny Aneurysm" Moment:
- ALL of the four lead actresses (playing women who had been cheated on and dumped) were considered for the role of the ultimate "Other Woman"—Alex Forrest of Fatal Attraction.
- The author of the novel, Olivia Goldsmith, died during a plastic surgery procedure. She died from the youth-loving and beauty-obsessed culture that she critiqued.
- One of the husbands ends up with a mistress that turns out to be underage and he's horrified as he had no prior knowledge of her real age. Nearly twenty years later in real life, Stephen Collins, who played one of the other husbands, admitted to willingly molesting children decades prior.
- Hilarious in Hindsight:
- As of now, all the younger women are in their forties and even their fifties, the same age our dumped protagonists are.
- The cougar/MILF phenomenon of recent years means that nowadays, the older women would be considered just as sexy and desirable as the younger ones, if not moreso.
- Hollywood Pudgy: Brenda obsesses over her weight in several scenes and is taunted about it by her ex's new girlfriend, when she couldn't be anymore than a size 10 or 12. It's particularly glaring in one scene where's she's thrilled at finally losing some weight, yet looks precisely as she has throughout the movie.
- She is seen wearing much baggier clothing near the beginning of the movie, seemingly trying to hide it.
- Hollywood Thin: Shelly. Brenda snidely comments that "the bulimia has certainly paid off" in reference to how slim she is. While she certainly is slim, she isn't unhealthily so.
- Memetic Mutation: "I beat Meryl!" When Jennifer Lawrence quoted this after winning a Golden Globe over Meryl Streep, some people (including Lindsay Lohan) thought she was insulting the other actress; she had to explain the joke on a late night show. This is especially funny since Goldie Hawn had previously starred with Meryl in Death Becomes Her.
- Retroactive Recognition: J. K. Simmons portrays an FBI Agent that arrests Morty.
- Tear Jerker:
- Cynthia's suicide. Before jumping off that balcony, she gazes at her college photo clearly missing those happy years of her life, when she was an ambitious straight-A student who didn't know yet what life had in store for her.
- Elise learning about Cynthia's suicide from a newspaper. She was before introduced as a self-centred White-Dwarf Starlet but that time she looks genuinely distraught. What's worse, another article next to the headline about Cynthia was about a nine-year-old boy who was hit by a car and clinging to life, and even worse, we never learn about his fate.
- The very premise of the film is quite sad - four women once best friends in college end up parting ways as they take different roads and meeting again only when one of them commits suicide out of loneliness.
- You also see them on their Graduation day, all optimistic. Elise was an ambitious starlet and experimenting with her hair and makeup. Brenda and Annie were much more enthusiastic and less insecure. Cynthia was so happy and the center of attention. The song "It's A Beautiful Morning" punctuates the joy of that day...only to cut to the present day with a lonely and depressed Cynthia.
- When the women temporarily break up and go their separate ways, we see how depressed they are and how empty they are feeling due to hitting a wall in their plan. This is all set to the aforementioned Billy Porter's "Love Is On The Way", making the scene all the more gut-wrenchingly sad. Then Elise, in tears, comes to Brenda's apartment and cries how she doesn't want to end up like Cynthia (especially after Brenda openly questioned Elise, who has a drinking problem, how drunk Cynthia must have been when she took her life.)
- Values Dissonance: Brenda's comment towards Shelly about being bulimic is very crude and mean-spirited, as eating disorders are a serious issue that many girls and women go through, that should never be joked about.
- Values Resonance: Although initially shocked/in denial about her daughter coming out as a lesbian, Annie is then nothing but supportive of her, so much that she went to the gay club that Chris frequented to show her support. Moreso, not only did she bring Brenda and Elise with her, Brenda then consoles a woman who lost her partner to a younger woman (and later pretends to be dating Elise in order to get her out of the club), while Elise is thrilled about being called beautiful by one of the clubgoers.
YMMV / The First Wives Club