- Actor Allusion: Yes, that's Luke Skywalker/The Joker voicing an effeminate robot not unlike an exaggerated take on C-3PO.
- Cross-Dressing Voices: Otto is voiced by Pamela Adlon, who often voices little boys (i.e. Bobby Hill, Milo Oblong — in fact, Otto's voice is closer to Milo Oblong's than Bobby Hill's) or, in the case of Recess and Pepper Ann, girls who look or act like boys (Spinelli and Margaret Rose "Moose" Pearson).
- Descended Creator: Some episodes have the show's creator Dave Wasson doing some voice work, including random civilians and animals including Mrs. O'Leary's Cow, Billynote , and a pterodactyl.
- Carlos Ramos, one of the main writers, note , voiced Napoleon in the episode "Napoleon the Conquered" and the Spelling Bee Champ in "Orphan Substitute".
- Keep Circulating the Tapes: Most fans today gain access to the show through websites including kisscartoon, and watchcartoononline, or through illegal downloading from torrents. Time Squad has never been officially released on DVD or Blu-Ray, nor is it available for streaming like most of the other Cartoon Network shows (past and present). If copyright strikes haven't taken them down yet, one might be lucky to find the entire series on YouTube or dailymotion every so often. The show did appear on Cartoon Network's website as part of its 20th anniversary in 2012, but only in clips, not full episodes. Dave Wasson's website had a Time Squad episode up ("Billy the Baby" — possibly because Wasson considers that episode his magnum opus), but no other full episodes (as of 2020, that website is no longer active).
- The episode "Dishonest Abe" did appear as an extra on the Powerpuff Girls VHS "Meet the Beat-Alls".
- In April 2020, Cartoon Network briefly added the first episode ("Eli Whitney's Flesh-Eating Mistake" and "Never Look a Trojan in the Gift Horse") to their app for viewing. Soon after the same episode was released on a wide range of other streaming sites, including Apple TV, Hulu, and Sling TV. This, however, was only temporary, and fans are waiting to see if Warner Media will include the entire series on HBO Max.
- Missing Episode and Schedule Slip: For reasons unknown, "White House Weirdness"note was supposed to air after "Repeat Offender"note but was replaced with "Ladies and Gentlemen, Monty Zuma"note It has been speculated that because of the stringent censorship about mocking the U.S. government that was prevalent after the September 11th attacks, depicting The White House as a haunted house would have been in bad taste.
- "Floral Patton" and "Orphan Substitute" (the final two episodes) were also held back because Cartoon Network was concerned over complaints about "Orphan Substitute"'s depiction of George W. Bush ("Floral Patton" being banned was a case of guilt by association, as this cartoon was made back before a show creator could do a 10-minute episode of his or her show and just mix and match episodes if one got pulled for content reasons[[note]] This ended up being all for nothing, as Cartoon Network aired "Floral Patton" and "Orphan Substitute" as part of a Thanksgiving weekend block in 2003 and some overseas Cartoon Network channels do air "Floral Patton" and "Orphan Substitute" in reruns with no censorship done to it.
- What Could Have Been:
- Dave Wasson himself was originally going to be the voice of Officer Buck Tuddrussel.
- According to show writer, Carlos Ramos, an episode centered on the Time Squad going back to the Garden of Eden to get Adam and Eve to partake of the forbidden fruit from The Tree of Knowledge was written, but never made (the main reason isn't known, but it can be speculated that the content would have pushed things a bit too far). Also: Tommy Chong (from the stoner comedy duo, Cheech and Chong) was going to be the voice of Adam, but Dave Wasson rejected the choice for being too obvious.
- Word of Gay: On the Talkin' Toons podcast, Mark Hamill and Rob Paulsen crack jokes about how "there was no ambiguity with regard to [Larry's] sexual preference." In fact, Rob Paulsen has made references to Larry's behavior in other episodes of his podcast.
Trivia / Time Squad