For trivia items related to Mickey Mouse Works, go here.
- Channel Hop: The show was dropped from ABC's line-up after airing the first 26 episodes due to the end of One Saturday Morning and the rise of ABC Kids; the remaining episodes premiered on Toon Disney.
- Keep Circulating the Tapes: The only DVDs available are the Compilation Movies Mickey's Magical Christmas (which does have the first episode ABC aired as one of the bonus features) and Mickey's House of Villains. The series is also absent from Disney+ (an absence widely believed to be a side effect of the ban on Song of the South, as its main characters also popped up from time to time on House of Mouse). Thankfully, fans of the show uploaded the entirety of it on YouTube (albeit with some changes for some of them, however).
- Kids' Meal Toy: McDonald's sold a set of six plush figures in their Happy Meals from February 2 to February 22, 2001. These consisted of Mickey, Minnie, Donald, Goofy, Daisy, and Pluto.
- Milestone Celebration: This Walt Disney Television Animation production was created apparently to commemorate and nearly coincide with Walt Disney's 100th birthday.
- Non-Singing Voice: Rob Paulsen for Hades in House of Villains. Despite the fact that James Woods did his own singing for the character in Hercules: The Animated Series, Paulsen does the line "Where everyone's a friend of mine", though Woods voices Hades' other singing line, "what a place for breaking bread!"
- The Other Darrin:
- Characters from older movies had to have replacements (seeing as how pretty much all of those actors are dead). For example, Ratigan is now voiced by Maurice LaMarche instead of Vincent Price.
- Jodi Benson, in addition to reprising her role as Ariel, replaces Paige O'Hara as Belle (which, ironically, she was considered for in the original movie).
- Kevin Schon replaces Nathan Lane as Timon.
- Though Russi Taylor was the "standard" voice for Huey, Dewey, and Louie, the triplets were voiced instead by Tony Anselmo doing his Donald Duck voice pitched higher (much like how they were voiced by Clarence Nash in the classic shorts).
- It should be noted that Anselmo performed as the triplets before, in the TV special Down and Out with Donald Duck.
- Akira Kamiya had retired as Iago at this point, so Tōru Ōkawa voices him in the Japanese dub.
- Roxanne's appearance in "Max's Embarrassing Date" has her played by Grey Delisle instead of Kellie Martin.
- By the time the last few episodes aired, Goofy's Latin American Spanish voice actor on all of his appearances since A Goofy Movie, Carlos Segundo, who additionally voiced Mike the Microphone, was unable to reprise the role due to a financial disagreement with Disney Character Voices International. Beginning with the last 6 episodes, Goofy has been voiced by Mario Filio ever since, while Mario Arvizu took over the role of Mike.
- Role Reprise: The series can pride itself on retaining a vast amount of the characters' original voice actors, or their regular voice actors at the time (such as Tony Jay as Shere Khan, a role he'd played since the Disney Afternoon).
- Uncredited Role: Outside of Toon City, none of the studios that worked on the shorts (The Walt Disney Animation Units in Canada, Japan and Australia, and Wang Film Productions) are credited for the shorts recycled from Mickey Mouse Works. This is mostly due to Toon City doing the wraparound sequences, as their work on the shorts is also uncredited.
- Unspecified Role Credit: Only the actors' names are listed (alphabetically by last name) in the end credits, with no mention of what characters they voiced.
