The guys start searching, and find several empty spacesuits, including Winston's. They presume he was made to disappear as well, but he's okay. Peter also finds a recording saying that the entity that's been making people disappear is at least a Class 7. Peter wonders if Winston is an impostor, but confirms he's the real Winston when he asks him where his bunk is and he (Winston) knows. Then, the five of them start searching, where they determine that the entity is a ghost, and it's absorbing people's "life force" to power itself, and that the victims will die if not freed before their life forces are fully absorbed.
The Ghostbusters and Slimer enter a lab to find the place a total wreck. Slimer sees a mouse and adopts it. The ghost shows up and attacks, so Peter shoots back. Winston tries to warn him that making a hole in the wall would be dangerous as they're in an outer compartment, but he's already made one. Slimer almost gets sucked through the hole, but they pull him back and seal it up. Unfortunately, when the guys split up and search some more, Ray, then Egon, get absorbed.
Peter, Winston, and Slimer go to the control room, which is locked. Then, they discover that the ghost is trying to use the rockets to slow the station down, sending it out of orbit, and escape before it crashes, so that it can feed off everyone's life force on Earth. Slimer goes into the control room and lets the other two in, then Peter and Winston get into a fight with the ghost. The mouse flies into a computer panel, Slimer flies in after it, and accidentally stops the thrusters by short-circuiting the computer. Peter and Winston shoot at the ghost, freeing the victims, then Slimer traps the ghost. Back at the firehouse, Slimer (whose accident has somehow made him glow) is given sunglasses.
This episode provides examples of
- Animal Testing: Implied when there's a mouse in the lab.
- Baby Talk: Slimer calls the mouse a "little mousey".
- Badass in Distress: Among those who get absorbed by the ghost are Ray and Egon.
- Badass Unintentional: Slimer and the mouse both unintentionally play a role in preventing the station from falling — the mouse because it ran in the right direction, causing Slimer to chase it, and Slimer for getting electrified.
- Comically Missing the Point: When Winston says he will be in space, Ray says, "Which space?".
- Did You Just Flip Off Cthulhu?: Peter yells at the ghost when he and Winston are zapping it.
- Distressed Dude: Several men, including a major, Ray, and Egon, get absorbed by the ghost.
- Eat the Camera: When Slimer screams, we see inside his mouth.
- Ectoplasm: When Slimer kisses Winston, he gets slime on his face.
- The Food Poisoning Incident: Discussed when Peter jokes that it may have been bad food that made the people disappear.
- Gratuitous Italian: When Janine tells Winston there are no messages, but he asks, "Are you sure?", she tells him again in Italian.
- Green and Mean: The main villain absorbs people's life forces and is green.
- Let's Split Up, Gang!: At one point, Egon and Ray take the port of the station, while the rest take the starboard.
- Loud Gulp: Slimer gulps when he hears that the ghost is planning to crash the station.
- Must Have Caffiene: Implied when we see Janine yawning and drinking a hot beverage, implying she's drinking either coffee or tea to get rid of drowsiness.
- Mythology Gag: Winston calls Slimer "spud", referencing Ray calling him a spud in the movie.
- Ocular Gushers: Slimer's tears spray out like a sprinkler when he cries over finding out Ray and Egon were absorbed.
- Oh, Crap!: Slimer nervously says, "Oh no!" when he sees the evil ghost in the control room.
- On Three: At the beginning, Peter tells Winston to shoot the ghost on the count of three.
- Percussive Therapy: Peter shoots Winston's pager due to his frustration at it.
- Platonic Kissing: Slimer kisses first Winston when he sees he's okay, then Egon and Ray when they're freed.
- The Pratfall: Peter is knocked onto his butt when he pulls Slimer out of the hole.
- Red Eyes, Take Warning: The red-eyed ghost absorbs life forces.
- Say My Name: Slimer yells, "WINSTON!" first when seeing his empty spacesuit then when seeing him in person, then he yells Egon and Ray's names when he sees they've been absorbed.
- Series Continuity Error: Winston mentions having wanted to go to space since he was a kid, implying he's never been before, when "It Ain't NASA-sarily So" had him accompany the others to space.
- Shout-Out: Ray says something about Pluto (the dwarf planet), and then jokes, "...or Goofy".
- Slapstick: Slimer nearly gets sucked through a hole and into space.
- Something Only They Would Say: Peter tests if Winston is real by asking him where his bed is.
- Space Episode: The episode shows the Ghostbusters and Slimer fighting a ghost on a space station.
- Stink Snub: Winston says that his bunk is "unfortunately" downwind of Peter's, implying Peter smells bad.
- Theme Music Power-Up: The theme tune plays as the guys are zapping the big ghost.
- This Is Reality: Peter says, after failing to lure the ghost away, "It always worked on TV".
- Wrong Genre Savvy: When Peter tries unsuccessfully to lure the ghost away, he notes that it works on TV.
