These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Alternate Character Interpretation: In Eleusis, Mark joked that his character is actually a homicidal maniac hunting for a blacksmith and dirt. He further jokes the antagonists and villagers are just trying to stop his reign of terror and are innocent townsfolk.
He actually has this assumption for most of the protagonists he play as who has a mysterious past/past they can't remember. Sometimes he's correct, and sometimes he isn't.
Broken Base: According to YouTubers who dwell in their Fan Dumb and Hate Dumb, you're either a Markiplier fan, or a Pew Die Pie fan. Weirdly enough, they've thrown Captainsparklez into the mix recently for reasons that are not entirely clear.
In his play-through of Penumbra, he immediately hated Clarence for making him kill Dr. Swanson, the only person with a cure for the disease in the game.
Mark was also deeply upset over the whole concept of Calm Time, in which he played a serial killer who was forced to kill everyone in the game. Including a young child and his mother. Imagine the white phosperous incident from Spec Ops: The Line and you'll understand why Mark got so upset.
Not only that, he played Calm Timeright after a session of DrunkMinecraft.
His playthrough of the Markiplier fangame Ripest of Fears starts out innocent (read: scary) enough. Then, Mark reaches the end and the game starts playing footage of his subscriber milestone V-logs. The revelation he has and the conclusion he comes to are a little heartbreaking, to say the least...