Characters / Osmosis Jones

Characters from the 2001 film Osmosis Jones.

For characters introduced in Ozzy & Drix, go here.

All spoilers are unmarked. Read on at your own discretion.

Main characters

Tropes applying to both

• Big Guy, Little Guy: Drix is the big guy to Ozzy's little/average height guy.
• Fire-Forged Friends: Ozzy and Drix start out as unlikely partners forced to work together and end the movie as true friends.
• Old Hero, New Pals: The tv series has Ozzy and Drix ejected from Frank and taken to an entirely new body where they meet an entirely new supporting cast.
• Primary-Color Champion: Ozzy is blue and Drix is yellow and red. They are the main heroes of the film and the tv series.

Osmosis "Ozzy" Jones

"Next time, I'll be the bad cop."

Voiced by: Chris Rock (movie) Phil LaMarr (TV series)

A hot-headed, impulsive white blood cell whose recklessness has put him in the police department's bad books, Ozzy finds himself having to save Frank's life when his body is invaded by the deadly virus Thrax.

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• All of the Other Reindeer: Most of his fellow officers mock him for trying to catch criminals alone, not to mention the infamous incident that caused Frank to puke on Shane's teacher.
• Blue Is Heroic: Even though he's a white blood cell, his color is a light shade of blue.
• Cassandra Truth: Ozzy is the first white blood cell to become aware of Thrax. However, his Cowboy Cop antics make it impossible for anyone other than Drix and to a lesser extent Leah to believe him. It isn't until Frank is on the verge of death that people start to realize that Ozzy was telling the truth.
• Cheshire Cat Grin: He sports one of these big, wide smiles every now and again.
• Cool Car: He had his cop car customized.
• Cool Shades: He occasionally wears a pair of black sunglasses.
• Cowboy Cop: Constantly ignores orders and goes rogue on the belief he can catch criminals by himself, to the point where he causes more problems for Frank than he solves.
• Determinator: Chases down Thrax outside Frank's body.
  Thrax: You just don't know when to quit, do ya, Jones?
• Dogged Nice Guy: Niceness downplayed. He has a little trouble winning Leah Estrogen's affections. He does at the end, though.
• Goofy Print Underwear: An X-ray scan when he goes to pick up Drix shows that he's wearing these.
• Grin of Audacity: He usually smiles in the face of danger to show that everything is going to be okay.
• The Hero: What did you expect after reading the title of the movie?
• I Did What I Had to Do: Ozzy had to eject a dangerous virus via vomit from Frank after the latter ate some raw oysters. He saved Frank's life in the process, but at the expense of his reputation and position.
• Idiot Hero: Osmosis, fast-talking aside, is not quite as bright as Drixenol.
• In-Series Nickname: He's always known as "Ozzy" when referred to by his first name.
• Jerk with a Heart of Gold: He's an egotistical Cowboy Cop, for sure, but he ultimately works for the best interest of his city.
• Large Ham: What else would one expect from Chris Rock?
• Master of Disguise: He can use his shape-shifting abilities to make himself utterly unrecognizable, other than his color. Heck, he can even make it look as though he has only one eye!
• Token Good Cop: He's a (white blood cell) cop who is good at both recognizing and battling threats. Many of his coworkers aren't, with his only reliable ally being Drix.

Drixenol "Drix" Koldreliff

"Special Agent Drixobenzometaphedrimine... Drixenol! The brand that eases your coughs and sneezes."

Voiced by: David Hyde Pierce (movie) Jeff Bennett (TV series)

A sugar pill taken to control a case of throat inflammation, Drix partners with Ozzy to resolve the Thrax crisis.

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• Arm Cannon: He utilizes his icy painkilling abilities by shooting blasts of frigid air from a cannon replacing his arm.
• The Big Guy: He's much taller and wider than Ozzy.
• By-the-Book Cop: Part of what makes him different from Osmosis — he's a stickler for procedure, which requires the two of them to adjust their technique. Once this is accomplished, they make a surprisingly good team.
• Captain Ersatz: Drix bears a strong resemblance to Iron Man.
• Deadpan Snarker: He always seizes a chance to make a dry quip at Ozzy's Cowboy Cop tendencies.
• Deuteragonist: As Ozzy's partner in both the film and the spinoff series, Drix is the second main character.
• Freeze Ray: His painkilling abilities are portrayed as ice blasts fired from his Arm Cannon.
• Genius Bruiser: An imposing, powerful, but also book-smart cold pill.
• In-Series Nickname: "Drix" is this, short for Drixenol (or Drixobenzometaphedramine).
• Motor Mouth: His introduction is delivered very quickly, in the manner of the narration that follows most medicine commercials.
• Nice Guy: Cordial, friendly and helpful.
• Only Known by Their Nickname: Nobody refers to him by his full name in the film, other than himself in his introduction.
• Red Is Heroic: His main colors are red and yellow.
• Slasher Smile: When pretending to be crazy to extract information from a flu vaccine. Complete with an evil giggle!
• The Smart Guy: He certainly acts smarter than Osmosis, at least. To be fair, he is intelligent and educated, Ozzy just has more experience, and Drix listens to him when it is prudent to do so.
• Straight Man and Wise Guy: The straight man to Ozzy's wise guy.

Frank Residents

Mayor Phlegmming

"Remember, a fat Frank is a happy Frank."

Voiced by: William Shatner

The short-sighted and self-serving mayor of the City of Frank, whose poor decisions and attempts to secure his own position led to Frank's deteriorating health and both began and exacerbated the virus outbreak.

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• Fat Idiot: He clearly doesn't see what could happen if he keeps giving Frank junk food instead of healthy food, hence the obesity.
• Hate Sink: As he is designed to represent and justify Frank's poor health, he inevitably ventures into this. Notably, he dismisses Ozzy from the police force for popping a pimple on Shane's teacher even though it was an emergency situation, fails to acknowledge Thrax as a threat despite the fact that he had killed others in the past (dismissing him as the common cold when he was one of the deadliest viruses ever), and is the only one that doesn't see the problem in giving Frank nothing but junk food (and is oblivious to how it's straining Frank's relationship with Shane).
• Head-in-the-Sand Management: He's so desperate to remain mayor, which he believes hinges on making sure Frank gets to a big BBQ event, that he'll resort to illegally using an override key (only permissible by vote of the Council) to make Frank take OTC medicine rather than go to the hospital when Thrax first starts showing his effects. If it weren't for Jones and Drix (who Phlegmming tries to get rid of), it would have been the end of the world for Frank's citizens.
• Insufferable Imbecile: He dooms Frank's health with his incompetence and ignores Ozzy's warnings over Thrax's invasion in favor of his re-election.
• I Reject Your Reality: His response to all the unfortunate things that Frank is going through.
• It's All About Me: Even when a threat to the city is imminent, he retains a shockingly solipsistic attitude.
• Jerkass: He certainly is, especially to Ozzy.
• Jerkass Has a Point: While he is a total douche towards Ozzy, Phlegmming has every right to be angry at his recklessness, such as disobeying orders and popping a pimple without a permit.
• Laser-Guided Karma: Abolished Ozzy for having Frank throw up to get out an evil virus. Then at the end when he's been booted out of office, he presses a similar button and winds up flushing himself right out of Frank's own body.
• Mayor Pain: Though he's not corrupt per se, he's very incompetent at his job and cares more about his re-election than anything else.
• My God, What Have I Done?: During Frank's near-death, Phlegmming shows remorse as he sees his city burning to the ground.
• The Napoleon: Is the shortest of all the adult cell characters^note to the point a cameraman can be shown crouching down to make sure he's in frame and easily the most egotistical.
• Obstructive Bureaucrat: Let's see, he fired Osmosis and gets Drix out of Frank just for popping a pimple without permit (Which is like blowing up a building in the real world) and as mayor control's nearly all of Frank's actions, including his slovenly behavior. Said neglect almost ends up killing the guy and every cell with him.
• Too Dumb to Live: His actions almost get his city destroyed. The end of the film shows he still hasn't learned his lesson about taking warnings seriously when he presses a button under a "Do Not Touch" sign and gets literally exiled from the body.
• Trumplica: He even resembles Trump.
• Underestimating Badassery: Thinks Thrax is no real threat to the city. Needless to say, he's very wrong.

Leah Estrogen

"Come here, baby. I'm still Jonesin' for a little more Osmosis."

Voiced by: Brandy Norwood

Mayor Phlegmming's secretary and who Ozzy is deeply in love with.

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• Damsel in Distress: Is taken hostage by Thrax, and very nearly killed by him.
• Everyone Has Standards: She's rejecting of Ozzy's advances towards her but even she thinks he doesn't deserve to lose his job when Mayor Phlegmming fires him.
• Graceful Ladies Like Purple: Her suit and even her body are both purple.
• Impossible Hourglass Figure: Downplayed, but her waist is still tiny compared to her bosom and hips.
• Jerk with a Heart of Gold: She may be aloof and unpleasant towards Ozzy, but she ultimately turns out to be a very good-hearted character, and even tries to talk some sense into Phlegmming.
• Office Lady: She works as a secretary for Mayor Phlegmming.
• Only Sane Woman: In Phlegmming's office. She is the only one who tries to talk sense into him, and is brave enough to confront him when his irresponsible ways cross the line. She also confronts Phleggming about his devil-may-care attitude towards an alert that the hypothalamus is under attack.
• "The Reason You Suck" Speech: She gives a short and to the point one to Mayor Phlegmming after he dismisses the blatant signs that Frank is suddenly starting to run a fever.
  Leah: You care more about your stupid re-election than you care about all our lives!
• Sassy Black Woman: Thanks to Brandy.
• The Smurfette Principle: Although Leah isn't the only female anthropomorphic cell in Frank's body, she's the only one with Nominal Importance.
• Tsundere: Type B. She's very rough around the edges, but her heart is very much in the right place.

Police Chief

Voiced by: Joel Silver

As the name implies, the chief of Frank Police Department who runs who runs a tight ship. He expects nothing but the best from Frank's Finest, but often clashes with Ozzy for disobeying orders.

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• Benevolent Boss: He expects nothing but the best from his police force, hence why he is upset with Ozzy going over his head. It's also heavily implied that he strongly dislikes Mayor Phlegmming and rightly believes his department's job to keep Frank healthy is becoming harder because of him.
• Everyone Has Standards: He frequently tells off Ozzy for going rogue and causing mayhem, but even he thinks Phlegmming firing Ozzy was a bit excessive.
• A Father to His Men: Cares deeply about the safety and the performance of all his officers, including Ozzy. Indeed, part of the reason he berates Ozzy a lot is because he genuinely wants him to do better, unlike most of the other police officers and Phlegmming who see him as a laughingstock.
• Jerk with a Heart of Gold: He may be at odds with Ozzy a lot, but he ultimately trusts him to do what's right.
• Kicked Upstairs: Does this to Ozzy by assigning him to the throat do deal with a case of pharyngitis, under the condition that he has a partner.
• No Name Given: His name is never given in the movie or even promotional material.
• Precision F-Strike: In the online game Mystery of the Rash Outbreak, he says "Get your nucle-ass in my office! NOW!!"
• Reasonable Authority Figure: He takes Frank's health much more seriously than his boss, and does see some value in keeping Ozzy in the force despite his destructive antics.

Viruses and Bacteria

Thrax

"Careful. I'm contagious."

Voiced by: Laurence Fishburne

A deadly and highly dangerous virus who enters Frank's body when the latter eats a contaminated boiled egg that had just been in the mouth of a zoo monkey, only to be dropped to the ground. Thrax aims to kill each new host he enters faster than the previous one, wanting to go down in the medical textbooks as one of the most deadly diseases in history.

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• Ambition Is Evil: He wishes to be remembered as the most dangerous virus in human history and earn his own chapter in the medical books. To reach his goal he's infected and killed numerous innocent people, and after doing the same thing to Frank, plans to beat his own personal record by killing his little daughter.
• Asskicking Leads to Leadership: He gets the bacteria to accept him as their new leader after single-handedly killing their prior boss, Scabies.
• Ax-Crazy: When it comes to Thrax and his desire to get in the medical books he will pile up as many bodies as he can, and he will do it all with a gleefully wicked smile on his face.
• Bad Boss: He kills both of his remaining underlings when one of them suggests laying low for a while, which would've derailed Thrax's plot to kill Frank within 48 hours.
• Badass Boast: When Scabies mocks him, saying he thinks he's the Ebola Virus; a disease infamous for causing, in some cases, uncontrolled bleeding out the eyes and orifices.
  Scabies: Look who thinks he's the Ebola virus! (laughs)
  Thrax: "Ebola"? Let me tell you something about Ebola, baby. Ebola is a case of dandruff compared to me!
• Badass Longcoat: One that he can use as a glider at that.
• Berserk Button:
  • Do not get in the way of his goal of being in the medical books. He killed all of his remaining men when one suggests they incubate for a while, since they are few in numbers.
  • He also doesn't take kindly to being looked down on, as Scabies found out the hard way.
• Big Bad: His plans to cause an infection of historical proportions are the reason why Frank is in danger.
• Big "NO!": He yells this when Ozzy tricks him into getting his claw lodged in a fake eyelash that is about to fall.
• Bond Villain Stupidity: Rather than using his One-Hit Kill claw on a dazed Ozzy during the final battle, he decides to strangle him using his DNA Chain. This costs him big when Frank's daughter blinks: he loses his grip on the chain, and when he decides to actually use the aforementioned Touch of Death, Ozzy manages to dodge it (by forming a hole in his torso around it) and get Thrax stuck, sealing the virus's fate.
• Breakout Character: Easily the character that people remember about the film the most. One of the most common praises Thrax gets is that he was just too good a villain for the movie we got, and that he should have appeared more. Along with Ozzy and Drix, Thrax tends to be a fan suggestion for Multi Versus.
• Cold Ham: Usually he keeps his voice very light and low, but he is also capable of letting real loose when excited, or angry, as shown above.
• Cool Shades: He owns a pair of sunglasses and wears them frequently.
• Creepy Souvenir: He carries around a chain of DNA beads taken from previous victims.
• Deader than Dead: Thrax meets a gruesome end by falling into a beaker of alcohol. We're shown quite explicitly that he is violently dissolved into nonexistence, never to trouble the world again.
• Deadpan Snarker: He tends to make dry comments about things he finds off, most notably on the somewhat low quality of Frank's criminal underworld, as well as his memories.
• Diseased Name: And a Punny Name at that, as his name is a play on the bacterial disease anthrax. This is a bit odd, however, considering that he's a virus and not a bacterium. It's possible that his name is purely for aesthetic.
• Disney Villain Death: Double Subverted. He falls, but the fall doesn't kill him — it's what he falls into that does. And we get to see it.
• Establishing Character Moment: Thrax's first appearance in Frank's gumline has him kill two saliva cells that were working to clean Frank's mouth^note Artie can be heard screaming as he is killed offscreen and the only thing that's left of him are his eyeballs in his vacuum pack, while Artie's co-worker is killed by Thrax's Touch of Death before setting their boat on fire, immediately letting the viewers know that he's an extremely dangerous and ruthless virus that poses a bigger threat to Frank than the other germs that were fought at the beginning. His ability to combust cellular matter, humming "Fever" by Little Willie John, and his quote "Think I'll turn up the heat in here!" are all used to foreshadow how he plans to kill Frank.
• Even Evil Has Standards: For as much of a serial killer Thrax is, just a couple minutes in Frank's dreams nearly gave him a panic attack.
  Thrax: This cat was sick before I even got here.
• Evil Is Bigger: Downplayed. He towers over every germ and cell we see, and only Drix is larger than he is.
• Evil Is Burning Hot: Thrax's immolating Touch of Death takes the form of one of his talons (the one on his left index finger) glowing red hot. His plan to kill Frank involves sabotaging his hypothalamus, which is the gland responsible (among other things) for regulating body temperature. Once Thrax steals an important component of the hypothalamus, the temperature skyrockets and deadly fires start breaking out across the city.
  Thrax: Think I'll turn up the heat in here!
• Evil Laugh: He lets out a very sinister one in one scene much to his goons' nervousness.
  Goon 1: What's so funny ?
  Goon 2: I don't know.
• Evil Sounds Deep: Courtesy of Laurence Fishburne, who is a baritone. His voice is considerably deeper than the raspy tenor of Osmosis Jones.
• Expy: Given his color scheme and extremely short action timespan, he's one of Edgar Allan Poe's Red Death from "The Masque of the Red Death". This is given a nod via a witness calling him "La Muerte Roja".
• Fame Through Infamy: He hopes that his murders will get him a chapter dedicated to him in the medical textbooks.
• Family-Unfriendly Death:
  • His Touch of Death has pretty gruesome results, and one of the first things he does is inflict this on an innocent cell. Said victim proceeds to boil alive from the inside out.
  • Fittingly, this ends up being Thrax's own fate; he falls into a beaker of rubbing alcohol and is completely dissolved.
• Faux Affably Evil: He's smooth, charismatic, and likes to hum "Fever" by Little Willie John, but is barely interested in coming across as affable, and will drop the charming act in a hot second.
• Finger Poke of Doom: Quite literally with his first victim. "Ow" indeed.
• Glory Hound: He intends to get his own chapter in the medical books and doesn't care how many bodies he leaves in his wake.
• Horrifying the Horror: Played for Laughs. When Thrax goes into Frank's subconscious, he's visibly disturbed upon seeing some of Frank's nightmares and bad memories.
  Thrax: [after escaping from the subconscious] Phew! This cat was sick before I even got here...
• It's All About Me: Given that he's single-mindedly concerned with racking up as many victims as possible in the shortest possible time, it's no surprise that Thrax is a profound egotist.
• Knight of Cerebus: Were you expecting a movie about Chris Rock as a blood cell to have a virus in the form of a serial killer?
• Lack of Empathy: He makes everyone around him (both humans and the organisms inhabiting them) suffer without any qualms whatsoever, and refers to his victims with the impersonal fondness one might use when talking about a mountain they've climbed or a game animal they've shot.
• Leitmotif: "Fever" by Little Willie John, though it's invoked because he's always humming it. The title alone suits him.
• A Molten Date with Death: How Thrax meets his end: after Ozzy traps him in a false eyelash that falls into a glass of rubbing alcohol, he's completely liquefied by it once he surfaces.
• Monstrous Germs: He is a red-skinned humanoid with tentacle-like dreadlocks and a large burning claw on one of his hands.
• Names to Run Away from Really Fast: Thrax, meant to evoke anthrax.
• Omnicidal Maniac: Thrax's plans involve killing people, causing the total extinction of entire civilizations of cells and microbes inside their bodies. The loss of life is apocalyptic at the cellular level, with an implied decimation among humans (since Thrax wants his own chapter in the medical books, he'd likely seek to become an epidemic, which would entail massive loss of life and be the microbe equivalent of a X-3 Apocalypse How at best and a Class X-4 at worst).
• The Perfectionist: Thrax wants to kill Frank in record time with hopes of getting his own chapter in the medical books.
• Playing with Fire: His fingernail claw burns whatever he scratches into a melting, burning lava mess.
• Red and Black and Evil All Over: Red-skinned, dressed in black, and definitely evil.
• Red Is Violent: He's a red-skinned homicidal and sadistic virus.
• Sadist: Beyond being the microbial equivalent to a Planet Destroyer, Thrax enjoys hurting others way more than he needs to in the pursuit of his goals. He taunts the odd victim before killing them or taking them hostage (the moment where he taunts Ozzy that he's going to infect and kill Frank's daughter after killing Ozzy is particularly noteworthy), and he breaks Bruiser's arm just to make a statement whilst taking over Scabies' crew. Furthermore, when Thrax reaches the hypothalamus, he kills the two hapless brain cells at the gland in needlessly creative and vicious ways instead of using his (admittedly already gruesome) Finger Poke of Doom on them: throwing one cell against the hypothalamus to be violently vaporized, and as a background bonus stabbing the other cell to death with multiple syringes to the back.
• Serial Killer: He keeps DNA beads stolen from each of his victims as trophies and reminisces fondly about them.
• A Sinister Clue: It's the hand he uses to kill all his victims and spread his infection.
• Sinister Shades: He sports a pair that, apart from making him look cool, give him an even more intimidating aura. He's prone to popping them on whenever he's doing something particularly destructive.
• Slasher Smile: He sports quite a few throughout the movie, the most notable one being when he threatens to kill Frank's daughter.
• Small Name, Big Ego: Evoked for drama. He's got maybe twenty kills to his name, is an unknown virus, kills via a lethal but otherwise unremarkable fever, and insists that ebola is a case of dandruff compared to him... ebola, the disease that's dreaded because it can have a mortality rate as high as 90% and cause people to bleed out all their orifices. His behavior suggests that he's aware of this, and that's why it's such a sore spot.
• The Sociopath: He'll kill as many people as it takes to get into the medical books.
• Terrorist Without A Cause: He's out for glory and a personal challenge; that's about it.
• Too Spicy for Yog-Sothoth: Frank's subconscious dreams actually succeed in freaking him out. It's one of the few times we see his effortless cool ruffled.
• Touch of Death: His left index finger causes any organic matter it touches to combust or explode.
• Vile Villain, Saccharine Show: It's a goofy buddy comedy full of gross bodily humor, and then along comes Thrax, whose long list of victims includes at least one small child.
• Villainous Cheekbones: Thrax's cheekbones are so pointy they look sharp, and he is clearly evil.
• Would Harm a Senior: He boasts that he killed an old man in 72 hours.
• Would Hurt a Child: Aside from threatening to have poor Shane join both of her parents in death after having her father die right before her eyes, Thrax previously killed another girl who didn't like to wash her hands.
• You Have GOT to Be Kidding Me!: He laughs at the fact that, for all the bodies he's destroyed, no one has ever figured out it was him. Osmosis Jones and Drix were the first to do so, but they were scoffed at by a foolish mayor and fired for it. Even he can't believe how easy they made it for him.

Scabies

Voiced by: David Ossman

• Alien Blood: He has green blood, as shown in his death-scene.
• All There in the Manual: His name was seen in tie-in media.
• Bad Boss: He shows no sympathy for his minion getting injured by Thrax.
• Defiant to the End: Even after being eviscerated by Thrax, his disembodied mouth continues to mock him before being sucked down a drain.
• Diseased Name: Scabies is named after the itching condition and caused a rash outbreak in the prequel game.
• Expy: A blatant one of Vito Corleone, AKA the Godfather.
• Family-Unfriendly Violence: He was mutilated by Thrax's index claw, and we get to see him bleed.
• No Celebrities Were Harmed: Scabies' mannerisms and voice were based on Don Vito Corleone from The Godfather.
• No Sympathy: Responds to Bruiser getting his arm broken by Thrax by mockingly calling him a "sissy Mary".
• Underestimating Badassery: Scabies didn't like Thrax's bragging and mockingly asked if he thought he was as dangerous as the Ebola virus. Thrax proceeded to show him why this was a bad idea...

Bruiser and Joe Cramp

Voiced by: Rodger Bumpass (Joe Cramp) and Herschel Barber (Bruiser)

• All There in the Manual: Joe Cramp's name is revealed through an unfinished tie-in action figure.
• Evil Sounds Deep: Bruiser has a pretty deep, gruff voice.
• Fedora of Asskicking: Joe Cramp wears one throughout the whole film.
• Meaningful Name: Bruiser has four arms and is quite tough, for a germ.
• Multi-Armed and Dangerous: Subverted with Bruiser: he has two hands on each of his arms, but doesn't get to show off his implied physical prowess in any way.

Outer World

Francis "Frank" DeTorre

"99 kinds of wings! 128 different dipping sauces! You love math, crunch the numbers on that - and tell me the possibilities aren't infinite!"

Played by: Bill Murray

The slovenly zookeeper whose body the film takes place in. He doesn't have very much regard for hygiene and health despite his daughter's pleas.

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• Bumbling Dad: He means well, and does care about Shane, but he has a major selfish streak. Though this is at least partly due to Mayor Phlegmming overriding his body for his own ends.
• Character Development: Frank goes from an idiotic slob to a man who's chosen to better himself and get into shape following a brush with death brought about by his poor dietary habits.
• Children Raise You: He is taken care of by his daughter.
• "Fantastic Voyage" Plot: The plot takes place inside Frank's body
• Fat Idiot: His diet is abysmal, but after his near-death experience, he decides to eat healthier.
• Guys are Slobs: Subverted, as we hear Shane complain that neither he nor Maggie, his deceased wife, took care of themselves very well.
• The Mourning After: Still mourning the loss of his wife, Maggie.
• Too Dumb to Live: What kicks off the whole plot as he eats an egg that was inside the mouth of a chimpanzee and got spat out onto the ground. Even worse, this isn't even the first time he's done something like that; he once ate a contaminated raw oyster while attending a science fair at Shane's school.

Shane DeTorre

Played by: Elena Franklin

• Accidental Hero: When she cries to say goodbye to her dying father, she unknowingly helps Ozzy save her dad, as he uses her tear to get back into Frank's body and return the hypothalamus gland Thrax stole.
• Broken Bird: Became this for multiple reasons, namely her mother's death, her father vomiting on her teacher and getting fired, a restraining order and a dead end job at the zoo as a result of it and finally, her being ostracized by her peers because of the incident.
• Children Raise You: Takes care of her dad, because he doesn't take care of himself.
• Gender-Blender Name: Her first name is predominantly used by boys.
• Missing Mom: Her mom died of an unspecified illness. Though it's implied she was as unhealthy as Frank has been throughout the movie.
• Only Sane Woman: Shane often has to be the adult between her and her father.
• What Happened to the Mouse?: Whereas Frank got a cameo appearance in the premiere episode of Ozzy & Drix, Shane was noticeably absent, fueling speculation that the cartoon was an alternate universe story instead of a sequel.

Mrs. Boyd

Played by: Molly Shannon

• Butt-Monkey: She was vomited on by Frank after he ate a contaminated oyster at a school science fair, then later got a face full of pus when a zit on Frank's forehead popped thanks to Drix's grenade.
• Disproportionate Retribution: Sure, getting vomited on can't be pleasant, but taking out a restraining order against Frank is a bit extreme.

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