YMMV / Osmosis Jones

  • Animation Age Ghetto: What inspired the film's overhaul from a gritty, profane PG-13 action comedy to a juvenile gross-out family flick and, ultimately, proved its failure.
  • Audience-Alienating Premise: For once, it was this and not a lack of advertisement on WB's part that caused the film to flop. The film couldn't blend the live-action gross out comedy with the animated buddy-cop as each portion only detracted from the other. Though given the success of another film that shows the inner workings of the human body, one might wonder that it was ahead of its time.
  • Complete Monster: Thrax is a deadly virus who is obsessed with infamy and making his name known in the medical books. To this end, Thrax infiltrates human after human and slowly kills them through an agonizing fever —one of his victims a little girl who "didn't like to wash her hands"—which comes with the consequence of killing both the human and every living organism inside of them. Upon invading the body of Francis "Frank" DiTorre, Thrax introduces himself burning a cell unfortunate enough to cross him from the inside out whilst humming, and cuts clean through a local crime boss to cow his flunkies into serving him. Thrax sets about murdering whomever comes in his way and burns his own flunkies to death after they suggest incubating, ultimately nearly succeeding in dooming Frank and gloating to hero Osmosis Jones that he intends on breaking his record on Frank's young daughter Shane. Perpetually suave even while brutally killing others and remarkably sadistic, Thrax darkened the mood of this otherwise-lighthearted Buddy Cop film tenfold whenever he was onscreen.
  • Draco in Leather Pants: Thrax has a pair to go with that leather jacket.
  • Ear Worm: If you're not a fan of rap, most of the soundtrack will get stuck in your head.
  • Ensemble Darkhorse: Even the movie's detractors claim that Thrax was the best part of the movie.
  • Evil Is Sexy:
    • Despite the fact that he is only vaguely humanoid, Thrax apparently falls under this.
    • It's the voice.
  • Harsher in Hindsight: Thrax describing Ebola as being a case of dandruff pales in light of the 2014 epidemic.
    • Thrax's name sounds similar to Anthrax. This film was released mere months before the Anthrax attacks that followed 9/11.
  • Hilarious in Hindsight: Pikachu makes a small cameo, being held by a germ. Pikachurrin, a protein, wouldn't be discovered until 2008.
    • Thrax declaring that "Ebola is a case of dandruff compared to me!" is made somewhat funnier by the arrival of ZMapp, Ebola's highly tentative cure. Could also be "Funny Aneurysm" Moment after the Ebola 2014 break out.
    • The movie showing the workings of the human body as a whole, including dreams, became this when Inside Out premiered in 2015 and (among other things) portrayed dreams as little movies like Osmosis did.
  • Ho Yay: Jones and Drix. I think I'd like to stay with Jones indeed.
    • Foe Yay: "You know what, Jones? You want this chain so bad, Big Daddy Thrax is gonna let you have it!" Indeed.
  • Hollywood Pudgy: There are lines in the script that seem to imply that Shane is overweight. It seems likely that was the original intent and they never changed the script, because the actress they wound up casting is a tiny thing.
    • Someone with Frank's habits and with the constant talk of how unhealthy he is should be a great deal more obese than Bill Murray.
  • Just Here for Godzilla: A lot people tend to watch the movie for just the animated segments.
  • Moral Event Horizon: Thrax horribly murders two cells in his introduction with his touch. If that's not enough, he reveals a collection of DNA from past victims. One of them was a little girl who didn't want to wash her hands. Another was a nice lady and yet another was an elderly man.
  • Narm:
    • Uncle Bob's reaction to Frank getting hospitalized. His "crying" honestly sounds like hooting laughter.
    • Frank eating food while trying to have a moment with his daughter about her mother passing away is such a pathetic sight that you can't help but laugh at it.
  • Nausea Fuel: Most of the movie, especially the scene with the zit and when Frank throws up.
    • In-universe, Jones nearly makes Drix puke (somehow?) by going into lengthy detail about his poor upbringing in Frank's butt crack.
  • Nightmare Fuel: Frank starting to die, both from his perspective and perspective of the inhabitants of Frank City.
    • Thrax murdering a white blood cell early in the movie. We see the white blood cell rapidly deteriorate and squirt liquid out of his eye socket!
    • For that matter, Red Death. He's killed several people before by stealing a part of the hypothalamus that controls body temperature, showing off a piece of jewelry with several of these bits. The thought of having a sudden, uncontrollable fever that will only go higher as time passes by...
    • One of his first victims was a little girl who didn't like to wash her hands. Even as a health-conscious person, one would expect a flu virus at worst- just think about her parents finding out that their child is dead from a disease that isn't even recognizable.
  • Paranoia Fuel: There's a lot in this film. Firstly, your body is made up of millions of fully conscious Cell Individuals; talking, crying, and living their millions of lives within you as you live about yours. Every time you cut yourself and blood drips out, that's a couple thousand people dying! Also, related to the Fridge Horror, your Mayor (with approval from City Counsel) has the ability to take over your brain and make you say and do things beyond your control.
  • The Scrappy: Frank is seen as such for being such a despicably unlikable slob to the point that many have noted that his daughter, Shane, would probably have been better off if Frank actually did kick the bucket. It doesn't help that at the beginning of Ozzy and Drix, he is shown back to his old self-destructive habits.
  • Ship Sinking: Osmosis x Leah goes down the drain when you include the spin-off show where Osmosis and Drix are forced out of Frank and transferred to a different body.
  • Signature Scene:
    • Frank eating the egg as it switches to the first animated portion of the movie taking place in Frank's mouth.
    • Thrax's monologue about wanting to break his record so he could have a place in the medical books.
  • Squick:
    • Frank picks up a hard-boiled egg and eats it. What makes this Squick? The egg has been on the ground in a filthy chimpanzee cage, and before that it was IN THE CHIMP'S MOUTH. Maybe all his unhealthy habits were affecting his brain?
    • It's more like the Mayor thing running his brain affected his unhealthy habits.
    • A horror film playing in Frank's movie theater (i.e. a nightmare from his subconscious) involves his daughter marrying his brother.
  • Tear Jerker: The "death" of Frank.
    • Also this from the same scene: "Your mom says hi."
  • Unintentionally Unsympathetic: Shane may have every reason to be telling her father how to improve his heath, but her Rightly Self-Righteous attitude makes her seem less concerned and more like an annoying little smarty pants.
  • They Wasted a Perfectly Good Plot: Many enjoy the inside-boy animated story and feel that the movie would be better if the poorly-received gross-out live action scenes were thrown out.
  • What Do You Mean, It's for Kids?: Originally, it wasn't, but it was neutered just enough to fit a PG rating. This apparently didn't apply to the blatant sex references, violent deaths, extreme gross-out humor and a Kid Rock song with a line glorifying statutory rape.

http://tvtropes.org/pmwiki/pmwiki.php/YMMV/OsmosisJones