Starring Eduardo España, César Bono, Macaria, Mayrín Villanueva, Ana Bertha Espín, Polo Ortín, Darío Ripoll, Pablo Valentín, Moisés Suárez, Manuel "Flaco" Ibáñez, and Danny Perea, with the star performances of Vadhir Derbez, Roxana Castellanos, Octavio Ocaña, Tanya Vázquez, María Prado, Yolanda Martínez, Markin López, Anaís, Saíd Casab, María Rubio, Luis Gerardo Méndez, Pedro Romo, Benjamín Rivero, Carla Zuckerman, Ahrid Hannaley, Georgina Holguín, Reynaldo Rossano, and others.
Vecinos has examples of the following tropes:
- Christmas Cake: Silvia. She is obsessed for getting married to prove her independence to her parents. She ends up failing in her goals due to either her potential suitors' personalities or the annoyances of her neighbors, until she finally gets in a relationship with Luis.
- Do Not Call Me "Paul": Frankie Rivers, every time her wife or any other neighbor calls him by Francisco or Pancho, demanding to be called by his stage name, which is basically his real name in English.
- Henpecked Husband: Arturo, Magdalena's husband. He always does as his wife says and never stands up to her.
- Historical Longevity Joke: Every time Don Roque says an "En mis tiempos.." (In my times...) remark, Pedro replies with these kinds of jokes.
- Lazy Bum: Germán. Despite being the one in charge of maintenance of the apartment, he often slacks off or plays at work, which is reason for the neighbors to call him out.
- Mock Millionaire: Magdalena López Pérez. She pretends to be from an affluent household and tries to cover up the fact she and her family are actually poor.
- Playing the Victim Card: Played for Laughs with Jorjais, the local homeless man.
- Prima Donna Director: Francisco Ríos, aka "Frankie Rivers". He passes the time writing scripts in a typewriter, abuses those who want to help him direct his future movies, and even forces his son Benito to act out roles for any play that he sees.
- The Thing That Would Not Leave: Pedro. He mooches off of Luis' work and refuses to get a job.