The Total Drama Do Over wiki lists the hypothetical voice actors for almost all of the original characters, decided by the characters' creators. Unlike canon Total Drama, this casting does not abide by Only So Many Canadian Actors and includes a variety of non-Canadian professional voice actors and even celebrities.
- Abigail is voiced by Brooke D'Orsay, the voice of Caitlin from 6teen.
- Charlotte is voiced by either T'Keyah Crystal Keymáh or Willa Holland.
- Felicity is voiced by Ashleigh Ball, since Felicity is an expy of Ball's character Applejack from My Little Pony: Friendship Is Magic.
- Vanessa is voiced by Olivia Olson.
- Robert is voiced by Richard Steven Horvitz.
- Shin is voiced by Chris Pine.
- Will is voiced by Jay Baruchel.
- Mel is voiced by Linda Cardellini, though there's also evidence that she was originally cast as Bryn McAuley, who later voiced Amy and Sammy in the canon Pahkitew Island.
- Nathaniel is voiced by Andy Berman.
- Adam is voiced by Lyon Smith, the voice of the Adversity Twins in Ridonculous Race.
- Candace is voiced by Miranda Cosgrove.
- Cheyenne is voiced by Anastasia Phillips, the voice of Lo from Stōked.
- Coby is voiced by Samuel Vincent.
- Colton is voiced by Troy Baker.
- Constance is voiced by Kyla Pratt.
- Desiree is voiced by Tara Strong.
- Fallon is voiced by Melissa Altro.
- Giselle is voiced by Stephanie Sheh.
- Harrison is voiced by Terry McGurrin, a writer for the canon Total Drama who voices Don in Total Drama Presents: The Ridonculous Race, Jonesy from 6teen, and Chris in the 2023 Total Drama Island revival.
- Jack is voiced by Greg Cipes, largely inspired by his work as Beast Boy in Teen Titans (2003).
- Krystal is voiced by Andrea Libman.
- Nicole is voiced by Stacey DePass, the voice of Emma and Crimson in Ridonculous Race and Nikki from 6teen.
- Randy is voiced by Doron Bell.
- Tanner is voiced by Steven Yeun.
- Zachary is voiced by P. J. Byrne.
- Michael is voiced by Scott McCord, the voice of Owen, Trent, Brody, and Jacques. Ironically, Michael and Jacques end up dating.
- B, a canon character, also has a voice actor assigned, as he doesn't speak in canon but has moments of dialogue in the fanfiction. He's voiced by Kevin Michael Richardson.
