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Jonathan Moon

Non-Action Guy: He's an architect, and must flee or sneak because he's unable to fight at all.
Player Character
Would Hurt a Child: He decides to kill the abominable baby of Willard, since it would keep the cult from sacrificing it to bring about the end of the world. Willard stops him from doing so, though.

Amanda Moon

And Now for Someone Completely Different: You play as her in the first level.
Damsel in Distress: She mysteriously disappeared one year earlier, and Jonathan's goal is to rescue her.
Everyone Is Related: It turns out she descends from a bastard child of Harriet Yelverton, which makes her or her descendants suitable victims for the sacrifice planned by the Cult of Ecstasy.
My God, What Have I Done?: Once Jonathan eventually rescues her, she initially refuses to leave the estate with him, crying that she no longer deserve him because she was complicit with the cult's activities.
Stockholm Syndrome: Admits to Jonathan that she started to enjoy the things the cult did to her.

The Cult of Ecstasy

General

Malevolent Masked Men: A cult of dangerous masked men worshiping an Humanoid Abomination and having orgies.
Secret Circle of Secrets: They wear robes and masks, they do orgies, and their goal is to merge Earth with another dimension whose inhabitants are mindless drones entirely driven by sexual instincts.

Willard Yelverton

Big Bad: He's the current leader of the cult.
Enfant Terrible: Doreen Austerlitz raised him this way, to make him a suitable leader for the cult.
Evil Old Folks: His actual age isn't specified, but Doreen Austerlitz helped raise him (she died in 1960) and the game is set in 2017, so he's at least 60 (at least: a Side Story illustration shows a teenage version of him next to Doreen Austerlitz).
Full-Frontal Assault: He's entirely nude in each of his encounters during the game.
Groin Attack: He has no genitals and a vertical scar on his groin.
Horned Humanoid: He sports a pair of antlers in-game.
Hypocrite: He calls Jonathan out for intending to kill the baby. He conceived and raised the baby in order to have a victim for a human sacrifice ritual...
Matricide: He's born from Benedict and a maid from Yelverton estate. He despised his mother and murdered her while he was a teenager.
Puzzle Boss: He's eventually confronted in the Lusst'ghaa dimension. The sequence consists of kiting him to make him cast spells in front of a sealed door, then fleeing once the door is broken. His actual demise happens later, without any player input.

Doreen Austerlitz

Posthumous Character: She died of disease in 1960, well before the events of the game happened.
Predecessor Villain: The Cult of Ecstasy has been created after her discovery of alternate dimensions. She's also responsible for Willard becoming the sociopathic current leader of the cult.

Benedict Yelverton

Disappeared Dad: He killed himself before Willard's birth.
Driven to Suicide: He hanged himself to escape the cult after learning that he was, at the time, the only suitable victim the cult identified for the sacrifice (being the child of a Seeing).
Posthumous Character: By the time the events of the game happen, he's long dead.
Screw This, I'm Outta Here: He founded the Cult of Ecstasy but distanced himself from it because he felt it became a club of "rich depraved". And that's before he killed himself to be sure to escape the cult.

The baby

Child by Rape: Although Amanda was pregnant with Ethan's baby when she was kidnapped, she was given a forced abortion and then raped and impregnated again by Willard. Just in case you were wondering how over-the-top evil this cult gets...
Humanoid Abomination: It looks like a very large human baby, with reptilian facial features and a tail.
Human Sacrifice: It was bred especially to be sacrificed by the cult to call the Lusst'ghaa dimension. Being born from Willard and Amanda, he descends from a Seeing and thus is suitable for the sacrifice.
No Name Given: Its name and gender aren't revealed.

Other human characters

Milton Yelverton

Driven to Suicide: Committed suicide shortly after the death of his wife Harriet.
Posthumous Character: Died in 1885.

Harriet Yelverton

Iauvr'abrarc

Greater-Scope Villain: The "God-King" of Lusst'ghaa and more or less the being actually worshiped by the Cult of Ecstasy.
The Unfought: You never meet him.