One of the most well known effects of alcohol is to loosen inhibitions, and if a specific inhibition is having sex with someone, that other person can use alcohol just for that.
Anyway, this trope is fairly common in fiction, but usually parodied
Compare In Vino Veritas
. Contrast Above the Influence
. See also Slipping a Mickey
No Real Life Examples, Please!
Yes, this is likely done in Real Life
, but in many jurisdictions, it is considered a form of statutory rape. That might just open a few cans of worms.
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Anime & Manga
- In Monster, Eva's unflattering flashbacks of Roberto heavily imply that the only reason she had slept with him was thorough inebriation. Whether he supplied the alcohol is, however, unclear.
- In a Digging Yourself Deeper moment early in the Air TV anime, Yukito frantically tries to tell Hijiri that he did not do this to Kano.
- An extra chapter of Strawberry Shake Sweet revolves around Julia and Kaoru trying this on their respective love interests. In both cases, it ends up spectacularly backfiring.
- The ending of Super Bad is all about this; it's a high school senior party where everyone is wasted. Discussed by several characters, most of whom believe that taking advantage of someone drunk is ok as long as you get drunk yourself.
- Is quoted in Willy Wonka & the Chocolate Factory by Wonka himself when explaining why there's alcohol (specifically "butter scotch" and "butter gin") in his chocolate factory.
- The Forty Year Old Virgin: Andy's friends try invoking this in order to get him laid. The drunken bachelorette he goes home with crashes her car and pukes on him. Great idea, guys.
- Subverted in 50 First Dates: one of the male lead's seduction techniques involves plying his dates with non-alcoholic beverages but telling them they're alcoholic for a placebo effect. This lets the women lower their inhibitions without reducing cognitive function, so nobody has to feel guilty.
- By Fridge Logic, Batman does this in the 1989 film - when Bruce Wayne has dinner with Vicki Vale, she drinks but Batman never imbibes alcohol, and then they have sex...
- Used for drama with Bonasera's daughter in the opening of The Godfather. A boyfriend and his friend made her drink whiskey with the intent of taking advantage of her, but when she resisted, they viciously beat her to the point that the undertaker says that "she will never be beautiful again." Bonasera's reason for coming to Don Corleone was to avenge this horrible wrong after the courts did not provide him with the justice he sought.
- One of the guys in Animal House is tempted to do this with Clorette, the mayor's daughter (who lied about her age to get into the frat party). He listens to the good angel and does not actually sleep with her, although everyone in town believes he did.
- A sleazy character plies an innocent young woman with booze and marijuana cigarettes for this purpose in Young Dr Kildare. It turns out she's a little too innocent, overdoses and passes out badly. The sleazeball panics, dumps her on the nearest bed and calls a doctor. She wakes up, clothing disarranged and lying on a bed in an obvious love nest, assumes the worst, and freaks out, running away. Sleazeball comes back to find her gone, and decides she's not his problem any more; he's wrong...
- In Rainbow Six (novel, not video game), a Casanova picking up girls in bars by getting them drunk turns out to be employed by the evil Animal Wrongs Group to abduct people to conduct bioweapon experiments on. If there's An Aesop there, it's rather heavy handed, Mr. Clancy.
- In The Forever War by Joe Haldeman, regimental doctor Diana Alsever tries some moonshine cooked up by, well, the regimental cook. She gets so plastered that she has no qualms about putting moves on the unit's commander, Major Mandella. Since this is a No Heterosexual Sex Allowed future — the major is the only member of the regiment old enough to be hetero — Diana must be really drunk. She passes out completely before anything interesting can happen, but Mandella makes a mental note to buy some good booze and get her alone if they ever make it back to civilization.
- Lot's daughters in Genesis 19:31-36, making this Older Than Feudalism.
- In one of the Company Z novels by J.T. Edson, one of the villains Company Z take vengance on is a rapist who plied a teenage girl with alochol-laced lemonade.
- In The Stone Prince, the prince is very reluctantly preparing for an Arranged Marriage, gets drunk with his bride-to-be, and they have sex. She remembers, he doesn't. Later, after they're married and he's inherited the throne, he's totally flabbergasted when she announces she's pregnant and furiously tells him off while both their Companions are watching.
- In Colby Rodowsky's Lucy Peale the title character was given a Pepsi with unspecified alcohol in it, and the combination of blurred reflexes and the seatbelt prevented her from physically resisting being raped in the backseat.
Live Action TV
- Massive case of ValuesDissonance is OntheBuses. Upon seeing that the home made brew they've put together has caused Stans sister and brother in law, who normally don't get along, to become so out if it they actually forget they forget they hate each other and start having sex. Stan and Jack decide to brew some more and get some women round with the plan to trick them into becoming so inebriated they don't know what they're doing so will have sex with them. This is depicted as harmless fun as opposed to sexual abuse.
- In Smallville, Clark is immune to the effects of alcohol just like all other earthly toxins, but he has his own personal replacement: red kryptonite. In Rush and Unsafe, he has some heavy making out with Chloe and Alicia respectively, but the red kryptonite is luckily (or unfortunately, if you prefer the relevant characters with Clark) removed before he does any irreparable damage.
- A more literal version in Fortune when everyone got drunk on enchanted alcohol, although most of what happened is left to imagination. Other than Tess and Emil's Home Porn Movie.
- From some of the bad dating advice Dave is giving Quentin in Grace Under Fire.
- Used by the doctor in Picket Fences. His date did try to sue him for rape, but the judge threw it out, noting what the guy did was stupid, but not illegal (in that jurisdiction.)
- Kennedy, from Buffy the Vampire Slayer, describing the lesbian dating scene:
"It's like flirting in code, it's using body language, and laughing at the right jokes. And looking into her eyes and knowing she's still whispering to you, even though she's not saying a word. And that sense that if you can just touch her, just once, everything will be okay. For both of you... [suddenly flippant] Or, if she's really hot, you get her drunk and see if she comes on to you."
- From The Inbetweeners:
Jay: If we're in charge of the alcohol, then we get our pick of the birds! The DRUNK birds!
Will: That sounded just a little bit rapey.
- In an episode of Chuck, a suave Bond-like spy attempts to teach Chuck how to seduce women as part of his spy training. A mission requires Chuck to seduce a very dangerous Russian woman. His first attempt is botched when he attempts to buy her a drink (as per the spy's instructions), only to find out that she doesn't drink. This prompts the spy to exclaim, "How is he supposed to seduce her without alcohol?" This either indicates his low faith in Chuck's charm or a limitation of his own seduction skills.
- In Community, the ill-advised decision is made to serve alcohol at an STD fair offering free condoms, leading to the expected consequence of a lot of horny, drunk young people planning on having sex with each other and with plenty of contraceptives available which, unfortunately, turn out to be faulty. Dean Pelton is apparently unaware that alcohol can remove inhibitions: "It makes me sleepy!"
- In Glee, Quinn gives her reason for sleeping with Puck as "[he] got me drunk on wine coolers and I felt fat that day." Getting her drunk in order to have sex with her was definitely Puck's intention.
- Has happened many times on Law & Order: SVU, sometimes in combination with date-rape drugs
- On My Name Is Earl, Joy (six months pregnant, with no idea who the father is It's Earl) is out with her friends at a bar, worried about how she's going to survive without a man since her parents kicked her out of the house. Joy then notices Earl, and knowing that he probably won't go for a pregnant lady on his own, she conspires with her friends to get him wasted, which they do. Then they introduce Earl to Joy. The next morning, Earl wakes up in a hotel room in Las Vegas, completely naked, with Joy...and a new wedding ring.
- How I Met Your Mother often portrays drunken hook-ups. In particular, in "Shelter Island" Barney sets out to get Robin drunk at Ted's wedding so that she'll sleep with him again. When he finds out the wedding only serves non-alcoholic beverages, he freaks out.
- Monica and Chandler's first hookup on Friends lampshades this trope to perfection:
Chandler: How drunk are you?
Monica: Drunk enough that I wanna do this. Not so drunk you should feel guilty for taking advantage.
Chandler: [beat] Well that's the perfect amount!
- The Flanders and Swann song "Madiera, M'Dear" is about a sly old man who attempts to get a young maiden drunk to sleep with her.
Unaware of the wiles of the snake in the grass,
Of the fate of the maiden who topes,
She lowered her standards by raising her glass,
Her courage, her eyes, and his hopes.
- A gender reversed version of this is in KISS' "Cold Gin".
- The Christmas song "Baby, It's Cold Outside" has this as an Unfortunate Implication when the female part of the duet inquires as to what else might be in her drink after trying to leave her date's house and being pleaded with to stay.
- The Bad Idea Bears in Avenue Q:
"Take her home! She's wasted!"
- In Guys and Dolls, Sky takes Sarah to Havana and gets her drunk. Since Sarah is a missionary who gives sermons on drunkenness, Sky needs to use a little finesse:
Sarah: Dulce de Leche... What's in it, besides milk?
Sky: Oh, sugar, and—sort of native flavoring.
Sarah: What's the name of the flavoring?
Sarah: It's very good. I think I'll have another one.
(several drinks later)
Sarah: Doesn't Bacardi have alcohol in it?
Sky: Only enough to act as a preservative.
- In La Ronde, the married gentleman seduces the young girl with wine. There may be something else in there too.
- The prevalence of this trope raises some Unfortunate Implications in Leisure Suit Larry: Magna Cum Laude. As Larry Loveage, your overall goal is to score with as many women on the college campus as possible. With several girls, especially Luba, this is done by getting them drunk via one or more minigames. However, it notably fails to work each time, because Larry is a Casanova Wannabe and has no luck whatsoever.
- A Dance with Rogues requires your character to be at least a little drunk to get into bed with Pia. Then again, the entire scene was staged for your "benefit"...
- In The Sims and its sequels, you can give a drink to a Sim your Sim is interested in. Said drink makes it more likely the target will accept certain social interactions that would be rejected sober. Giving more drinks increases the receptiveness.
- In the Mass Effect 3 Citadel DLC Shepard can resort to this to romance Vega.
- In 8-Bit Theater, Black Mage attemptes to further loosen-up the already confused White Mage with liquor. He ends up having to settle for paint thinner. The Black Comedy that might have ensued is only barely avoided by White Mage's Heel Face Turn.
- In Groovy Kinda, when she's closest to being sober (a relative term), Edison Lighthouse calls to mind a 1950s television housewife. As her day and her drinking progress, she begins to lose both her buttons and her inhibitions.
- A recurring incident in Girls With Slingshots is Hazel and Jamie getting wasted. Naturally, at one point it ends with Hazel seducing the bouncer, and Jamie waking up in bed with the (female) bartender. This leads into the storyline of Jamie exploring her possible bisexuality.
- Out There: In a slight tweaking of the trope, Rod gets falling-down drunk while attempting to seduce Miriam, who is spending a rare evening abstaining from alcohol.  Miriam doesn't want Rod to attempt to drive in his condition, so she insists he come home with her. Not wanting to be tempted, she gives him her bed while she sleeps with Sherry. It is not until the morning, when both Miriam and Rod are completely sober, that she succumbs to his advances. 
- May have caused a Broken Base for Sailor Sun when the much-debated origin of the gender-bent heroine's Kid from the Future was finally revealed as "Got drunk, woke up pregnant".
- June pretty much uses this method to take advantage of Pembroke in Femmegasm
- Chydossa tricks Graham into getting completely trashed in Wizard School with the line: "My God. I get so horny when a man has money and I drink lots of alcohol." (Bear in mind, she didn't exactly have to force him...)
- In Bob and George, the Author, drunk, sets out in search of a female.
- Quagmire of Family Guy is always trying to get the girls he meets drunk, though in general that also involves other date rape drugs. His favourite bar serves roofie coladas specifically for him.
- Phil from Harvey Birdman, Attorney at Law was in the court isle during the episode "Death By Chocolate", in which charges are pressed against Boo Boo Bear. He says to a bunch of monks, "You know what I always say. Gandhi is dandy, but liquor is quicker. Ha ha HA! ...Quicker." The monks then begin to ponder on the subject.
- On Clone High USA, Abe and Gandhi want to provide the beer for a party to loosen up Cleopatra. But, because they are underage, they are only able to get nonalcoholic near beer and lie to everyone.
- Dr. Krieger often cheerfully drugs people for various unsavory reasons, sex and dating among them.
Pam: And that's the reason I never have sex with my coworkers. That, and...nobody lets me.
Krieger: I've had good results with ether.
- In a later episode, he has this to add:
: Trust me, you can't control a person's heart. Krieger
: You can with a little something I like to call a deep cycle marine battery
] Or LSD. Cheryl
: IS THAT WHAT YOU'VE BEEN GIVING ME?! Krieger
? Point is, emotions like love don't come from the heart, they come from— Archer
: (Gasps) The brain! Krieger
: Yeah. [Beat
] Or LSD.