Eye trauma is a mainstay in the manga by Suehiro Maruo: people are blinded (sometimes self inflicted, always bloodily) with anything from needles to katana; eyeballs are dug out of their sockets with spoon and fork. On a more gentle side, licking of eyeballs during sexual acts is his trademark.
The Ryugu Shelter arc from 7 Seeds includes a disease carried that involves parasitoids that feast off the host's body for as long as possible. Once the incubation time is through, the parasitoids eat their way out through the eyeballs!
In Afro Samurai, Brother Two is forever using a pair of digital binoculars. He dies when Afro pulls his eyes out and shoves the binoculars into his skull — complete with one last shot of the binocular viewpoint, blood oozing over the lenses.
Angel Core. A 2 episode hentai OVA. There's this disturbing scene with some militia guys ready to torture and rape two girls. One of them takes a knife and gouges out the eye of one of them. In pain she begs them to give it back to her, but the soldier simply smash it with his boot and says "oops!". Not happy with that, one of them suddenly gets the idea of raping her through the empty and still bleeding eye socket. Thankfully, it didn't happen, thanks to the other girl begging for her.
In Another, Mei Misaki lost an eye as a little girl due to illness so she has a fake one behind an Eyepatch of Power. In the manga, however, she gets stabbed through her empty eye by Izumi Akazawa
In Attack on Titan, one unlucky scout lost his eyes (among other injuries) when his team was overwhelmed by Titans summoned by the Female Titan. As a Titan prepares to devour him, he spends his last moments begging someone to warn the other scouts of the Female Titan, unable to see that he is the last survivor of his team (for a few seconds anyway).
Gouging a Titan's eyes out is a fairly viable tactic, as they recoil in pain and are blind until they regenerate them. This presents humans with a window of opportunity to go for the neck and put the abomination down for good.
Let's cut the chase: She played with gunpowder as a child. She hasn't learned her lesson, either — she keeps a spare bomb in her empty eye socket!
In the light novels, Firo takes one of Huey's eyes as part of a plan orchestrated by Renee. Huey actually is willing to accept this, as long as he gets one of Renee's eyes in return. Furthermore,Huey's daughter Leeza gets revenge on Firo by taking one of his eyes. "An eye for an eye" was in full force during those novels.
Shouko does that even on the slightest instant she suspects Yuuji to be a little sexually liberated.
Hitagi Senjougahara from Bakemonogatari nearly stabs Koyomi Araragi in the eye with a mechanical pencil after he so much as talks about another female using her first name without an honorific.
Araragi-kun, your wounds heal very quickly, don't they? So I bet it'd be okay if I just took out an eyeball.
She also jabbed him in the eyes with her fingers once for referring to her as Senjougahara-chan rather than Senjougahara-sama like she wanted.
Baki the Grappler has a lot of attacks aimed to the eyes, but most are avoided. Early on the series, Baki fights against a giant, intelligent and vicious ape, and pops its eye with his bare hands. The beast screams... and then it completely rips the eye and eats it.
Inverted in a later chapter when Baki breaks someone's fingers hitting them with his own eyeballs. He was also crying blood after it, but still...
The manga version of Battle Royale has several, mostly courtesy of Kiriyama. The first comes in a flashback scene where a bullying Judo teacher made the mistake of pushing Kiriyama around, and Kiriyama simply stuck a finger into his eye, then dragged him around by the stalk for a bit before squashing the eyeball between his fingers. Later in a fight with Sugimura, Kiriyama stabs Sugi in one eye with a handmade wooden throwing dagger…
The movie version has Kiriyama walking out of a burning house with bleeding eyes... Well, those used to be his eyes, anyway. It's heavily implied his eyes were either pulped in the explosion, or were sizzled out of his head by the flames. Granted, he still puts up a fight, blindly firing an uzi at the main characters before having his head a-splode.
During the horrific finale of the Berserk anime, Guts gets his right eye clawed out by a demon as he is held down by said demon and forced to watch as his former commander Griffith, who has become the fifth member of the Godhand Femto, rapes Casca.
What's worse is that Guts remaining eye gets repeatedly threatened in the following arcs.
Chakrams can cut eyes in half…
One of Bishop Mozgus' disciples uses red-hot pliers to pull eyeballs out…
According to the manga, a good solid punch to the head will make your eyes pop right out. Every time.
Also, Miura seems to have a fondness of drawing people's heads getting cut in half, right at eye level. Graphically.
And getting stabbed or shot in the eye with an arrow takes the eyeball with it.
Also, in the very beginning when Guts is fighting the Baron of Koka Castle. First, the Baron loses his left eye when Guts blows his head in half, then he loses his right eye when Guts shoots it with his crossbow during wholly unnecessary but well-deserved torture.
Casca stabbing one of her would-be rapists in the eye with a stick and then the same guy gets his remaining eye gouged by one of Judeau's knives a moment later (only in the anime). The guy had it coming, but still. *shudder*
Serpico stabs a kelpie through the head, and then next page we see its left eyeball dangling from the socket.
In the first episode of the second season of the Black Butler anime, Alois suddenly stabs his maidservant Hannah in the left eye. With two of his fingers. Why? "A maid should never look directly at her master!" The other servants understandably have an Oh Crap! moment, but are then commanded to clean up the bloody mess.
And at the end of episode 8 it appears that Hannah stabs out Alois's left eye as well.
In episode 9, a boy goes around stabbing out the eyes of several young boys.
In the manga, Freckles aka Doll has bangs that fall over a majority of one side of her face to cover some sort of disfigurement or scarring and a very damaged eye.
Ciel himself was subject to this when he made the contract with Sebastian. Getting that insignia on his eye was not without screams and blood.
"I've noticed that's a thing, with anime that likes to be violent; they really like having eyeballs squish out of skulls."
Used then averted in Bleach when Kenpachi uses this against Nnoitra. He stabs his opponent's eyepatch as he's going to attack, saying that the eye socket is the most vulnerable place, something he knows from experience on account of having killed other people who claim their skin is too tough cut by just stabbing them in the eye. It turns out that Nnoitra's eyepatch is actually to cover up his complete lack of eye; where his left eye is supposed to be is his Hollow hole.
Kenpachi himself could qualify. He has both his eyes, but the one deliberately covered by the eyepatch has some kind of thing on the inside, with teeth, devouring Kenpachi's overflowing spiritual pressure. Developed by the 12th division, indeed.
At least one ability of Ulquiorra's requires him to pull out his own eye and then crush it in his hand. Made less disturbing by the fact that it grows back later. Made more disturbing by him spending the rest of the scene standing around unconcernedly with a gaping eye socket, though in the anime he closes his eyelid.
And in chapter 450 of the manga, Ginjo seriously injures Ichigo's eyes during their fight. Lampshaded by the chapter's name "Blind Solitude". Though Ichigo gets better in the following chapters.
And later, during Ichigo's fight with Ulquiorra, Loly and Menoly show up again, torture Orihime, and try to kill her again. When Ichigo notices this he charges after them in anger, and Loly threatens to tear out Orihime's eye. She didn't get the chance to, but clearly wanted to, given her irrational jealousy towards the girl.
In 664, Askin subjects Urahara to this by using his Vollstanding to create a Poison Ring, grafting said Ring in Urahara's eye, and then imploding it.
In Busou Renkin, Tokiko tries twice to gouge out her enemy's eyes with her fingers. As Watsuki says in the liner notes, "Tokiko loves to go for the eyes."
She even does it to Kazuki in the last chapter, when he's looking at her funny.
Happens twice so far in Cage of Eden. First, the characters fall victim to poisonous berries that cause their eyes to become bloodshot, until the are swollen with blood and they burst. Squick. Later, a large bird rips out and swallows the eye of its still-living prey.
Happens when the fact that some of Index's bites are apparently going for Touma's eye sockets.
Shiage gouges out Mugino's eye. She gets an artificial one later.
Othinus gave up her right eye for the power of Odin. She reveals that if her eye is returned to her, she will lose her powers and become human.
Episode 11 of Charlotte features Yuu getting his right eye slashed by one of the terrorists.
Also just barely subverted in episode 7, where Yuu considers doing this to a guy he fights, though there's still an extended shot of him holding a skewer over the guy's eye.
Choujin Sensen: Readers should expect a few eyeballs being gouged out during each fight.
CLAMP seems to have a definite eye fetish for all the times characters end up losing/going blind in one eye. Depending on how dark the particular series is, the event may be a comparatively gentle loss of sight in the eye while the eye itself remains intact; in other cases, however, the eye itself may be physically damaged or even violently torn out. There's generally a "loss of innocence" or "uncomfortable revelation" motif tied to the loss of an eye, but it's also often played as a dramatic sign of devotion. This trope, along with another trope they're known for has become so prevalent in their works, in fact, that their fanbase's motto is "every time you deny a shounen-ai pairing, CLAMP put another eye out."
Seishirou Sakurazuka in Tokyo Babylon loses an eye while protecting his special friend Subaru, and it was implied that he would likely go blind in the other eye as a result.
Subsequently in X1999, Subaru gets his eye torn out by Fuuma during their fight. Since Fuuma's gig at that time was granting people's darkest innermost wishes, it turns out that Subaru wanted to lose his eye out of a feeling of guilt for Seishirou losing his eye back in Tokyo Babylon. (He even briefly sees Fuuma as Seishirou, ffs!)
In the manga, Fuuma finds and then gives Seishirou's good eye to Subaru after the other's death. It seems Seishirou's wish was to eliminate any mark left by another man on Subaru. By accepting the eye Subaru also accepts Seishirou's powers and title as the Sakurazukamori, AND his role as a dragon or earth. It is later revealed that he does not wish do die anymore because it would mean that Seishirou's eye would die with him.
Doumeki and Watanuki go back and forth over this one in Xxx HO Li C. After Doumeki brushes a demonic spiderweb off Watanuki, he starts to go blind in one eye as a result of the spider demon's vengeance. Watanuki then makes a deal to take the spider demon's vengeance on himself, resulting in him going blind in one eye. Doumeki gets pissed off when he finds out that Watanuki has done this, and strikes a deal that he will share half his eye with Watanuki, giving them both oddly colored but functional eyesight.
Kokuyo in Wish gives Hisui his left eye as a sign of their lovers' bond.
In the Tsubasa Reservoir ChronicleWham Episode, Fai uses magic openly for the first time when attempting to prevent the clone of Syaoran from losing his soul and turning evil. When he fails, the clone rips out his eye and eats it. He intended to go on and eat the other one as well, but he got interrupted.'
In episode 5 of Blood-C, Saya fights an Elder Bairn that has an eyeball for a head, which leads to this. And in the end of Episode 12, Big Bad Fumito blasts Saya in her left eye, also blowing off quite a part of her head. Good thing that Saya has a massive Healing Factor and thus lives to tell, but it still takes her a while to heal; in the meantime, she rips her skirt and uses the piece of cloth as an Eyepatch of Power.
Another fan (or possibly detractor) meme riffs on an old American proverb: "It's all fun and games until someone loses an eye... and then, it's a CLAMP manga."
In the first episode, Jet grabs a thug in a headlock and threatens to jab him in the eye with a broken beer bottle (after having smashed the thug's buddy in the face with the bottle). Also in that episode, after dropping his injector, Asimov attempts to squeeze the bottle carrying the drug he's been using directly into his eye only to shatter it, getting glass shards in his eye.
In the Code Geass spin-off Manga Suzaku of the Counterattack, Schneizel prevents Lelouch from using his Geass on him by puncturing his left eye.
In Chrono Crusade, Jenai had his eyes sliced out during a battle with Pandaemonium. Later in the series he takes off the visor he wears over his blind eyes and reveals the badly stitched-up eye sockets, explaining how the Greeks used to put coins in the eyes of the dead to help pay for their fare on the River Styx...and then proceeds to pull out bloody coins he keeps in his eye sockets, offering to pay the heroine's way to the afterlife. It's a very, very creepy scene that establishes him firmly as a villain, although his blindness is also portrayed sympathetically in a later scene.
In the "Conclusion: God's War" manga arc of Cyborg 009, Francoise aka 003 get subjected to this andloses an arm. She's outfitted with new ones, but is so traumatized by the shit that's going on that she comes to hate them and tears those ones out after a while, and spends the rest of the arc completely blind.
Ayumi's standin for Yuki being eyepoked and murdered in a flashback is also very explicit compared to the game.
In D.Gray-Man, Road Kamelot directs several sharpened candles towards Allen. All of them miss except one, which lands straight into his left eye. Doesn't help that's the eye that detects Akuma either… It gets better, though.
And then we get to see his partially regrown-but-still-not-there eye-socket!
How he got the curse on his eye: in the backstory, when the resurrected Mana was ordered to kill Allen, he sliced up his face all around his left eye, leaving a very obvious scar and an Akuma-detecting curse that another character quickly ceases to think of as lucky for Allen when he briefly ends up sharing it.
From the manga Dead End: (paraphrased) "Do I look okay? I have needles where my eyes are supposed to be!"
In Deadman Wonderland, participants who lose in the Carnival Corpse matches have to play a game of roulette to determine which body part of theirs will be removed. After Senji is defeated by Ganta, his right eye is torn out in consequence for research (though he gets better within a couple of chapters.)
In The Demon Ororon, Othello decides he likes Mitsume's third eye, so he rips it out and swaps one of his own eyes with it.
In the Non-Serial MovieThe Last Wizard of the Century, the three murder victims are shot through their left eyes. The killer, a Dark Action Girl named Seiran "Scorpion" Hoshi, does so because she's a descendant of Rasputin, whose post-Rasputinian Death body was found without its left eye. She attempts to do it to Conan, but his new bulletproof glasses save him. Oh, and one of the victims survived — he was Kaito KID and he was wearing a special High-Class Glass.
Also, one of the VERY few hints about the Number Two of the Black Organization's identity is that they lack an eye. (The others are that he's a man and anoher is that he uses a cane.) Among those who fit in are the aforementioned Inspector Yamato and his boss, Hyoue Kuroda, a Badass Grandpa who has half his face horribly scarred around his eyes.
The Digimon Tamers movie "Runaway Locomon" features a battle against several big eyed digimon. What is disturbing (but not surprising) is to see the main character impale several of them through the eye, cutting them with the tip of his lance, complete with green slimy liquid coming out of it. This aired on Disney which edited just the graphical cutting and impaling of the first monster; the others though...
In Dog Days, Adelaide shoots Valerio in the eyes. Played for Laughs, as they heal up instantly and Valerio has a comical reaction.
In Dogs: Bullets & Carnage, one of Heine's flashbacks shows Lily reaching up to caress Giovanni's face... and then gouging both his eyes out with her thumbs.
Badou also had an eye cut out years before the current storyline.
Iris and Anemone of Dokuhime are identical twins belonging to a group in which perfect beauty is a prized attribute. Anemone loses an eye falling from a cliff, and being no longer perfect, must be removed from the group, either voluntarily becoming an assassin or being killed. Iris, her face still perfect, is allowed to remain, but instead chooses to poke out her own eye with a glowing branch from the fire, in order to remain a reflection of Anemone.
"I am Iris's right eye." "I am Anemone's left eye."
Vegeta got an eye taken out in his battle with Goku in Dragon Ball Z. It got better.
Vegeta(after getting hit for the third time in the right eyesocket):"The Eye! The Eye! Why is always that goddamned eye!?"
According to Yoshihiro Tatsumi's autobiography, A Drifting Life, his older brother never lost a fight with the local bullies, despite his crippling Tuberculosis, because he'd always go straight for their eyes.
The manga Durarara!!, depicts Erika and Walker torturing a man by imitating a scene from Black Butler, by branding his eye. It's a very disturbing reveal of just how devoted they are to their anime and manga - although they're also quick to note that if it wasn't anime and manga, it would be something else that they would take their inspiration from. In the anime, it's Played for Laughs, by just seeing comical struggling from outside the van, just barely skimming over how twisted these kids are.
In Elfen Lied, Bando, after getting his limbs mangled by Lucy's strong-enough-to-split-a-tank-in-two psychic powers, vows revenge by saying, "The next time I see you, you're dead." Being the amoral, violent sociopath she is, Lucy quicklysees a way around that…
Given the general dark, gory tone of Elfen Lied, he was practically Tempting Fate.
When she was younger, Lucy killed another girl who betrayed her by slamming two of her vectors through the girls head, with only bloody eye sockets remaining where her eyes had been.
Tears of blood are one of the first signs that you are a victim of the virus in Emerging. It quickly progresses into blood gushing from your eye sockets, as well as your other bodily orifices. To top it off, just before your death your eyes start melting.
End of Evangelion loves this. Unit 02 takes a Lance of Longinus replica to the face, causing Asuka to have her left eye put out. Later, Shinji causes Instrumentality to fail by bursting through Lilith/Rei's eyeball with the Lance of Longinus after being absorbed through a vagina-eye in her forehead. Dead fucking serious.
Also in the series itself: In the very first fight with the 3rd angel, Unit 01 gets shot repeatedly in the eye by the angel's laser at point blank range. The result? Unit 01 flies back about 100 yards and bleeds profusely out of both sides of its head where it was shot.
In End of Evangelion, during Asuka's "I don't want to die" bit, the viewer is treated with several flashing images including a picture of a decaying Asuka with a sewn-up mouth and maggots crawling out of her hollow eye sockets. Long story short Evangelion has a thing for horrifying people.
Fist of the North Star has a handful, not counting the dozens of Mooks who experience this just before (or when) they die. Spade is the first named victim of this after Kenshiro deflects his own arrow back at him.
Airi (Rei's sister) blinded herself after being subject to forced prostitution. Kenshiro cures her of this, however.
Shuh (almost) completely blinded himself in order to save a young Kenshiro's life.
"I offer you my light."
Akashachi lost an eye when he tried going to the Land Of Asuras.
Shachi rips out one of his own eyes in order to protect a wounded Kenshiro.
HOKUTO: ZANKAI KEN! it may not seem, depending on the angle... But, considering his thumbs pierce the flesh and might as well be BEHIND one's eyes doesn't make it any easy...
Added to the fact he presses two pressure points that actually increases the flow of blood on the had causing one to bleed to death after some time. And the location of the points? Yes, behind the eyes.
Fruits Basket: In Hatori's backstory, when he tried to get permission from Akito to marry Kana, Akito's violent disapproval ended with Hatori's left eye getting badly injured, while Kana was watching. The event traumatized Kana to the point where Hatori decided to suppress her memories of their time together so that she wouldn't be in any more pain.
Bootsvorz loses his left eye (along with his left arm) in a serious crash during an F1 test with Osamu in their backstory. He gains a modulation eye as well as a cybernetic arm after the accident.
Also happens to Osamu when Smith attacks his car from behind with his helicopter missile which results in injuring his eye. He didn't notice the effects of it until he returns to racing — it gets to the point where he nearly goes blind and he retires from racing because of that incident.
Boville of Gankutsuou has a glass eyeball which he cleans at one point before putting it back into his empty eye socket.
In Ga-Rei -Zero-, Yomi is pierced by 108 magical spikes. Not only were they targeted at every tendon and nerve cluster in her body, but two of them end up in her right eye. After the attack, there's a lingering closeup of her face...
Our hero does this to Junnosuke (both eyes, horizontal slash) and later Baian (one eye, vertical slash) of the Tengen Ryuu. The elite swordmaster Gensai Kizaki has a penchant for chopping the arms and eyes of those who get too close to him.
Misaku Nikaido took an interest in a young Shinnojo Sakura when the latter, despite being beaten, managed to slice his right eye. Several years later, when they settle things up, Shin finishes him off by stabbing his other eye (the tip of the sword was jutting out of his head) and slicing it off.
Later, both Iori and Shin tends to finish their opponents off by cutting their heads in half slicing the eyes as well.
Gangsta: Worick's father burned out his left eye with a cigarette during a drunken rage. What a dick.
In Gate, the Flame Dragon's hide is nigh-invulnerable, but its eyes are not. Tuka's father takes out the left one with an arrow. Later, the JSDF targets the right one with their guns, but it manages to block the bullets with its hands.
In the Get Backers manga, Kazuki tears out his eye with the Stigma on it. You get a nice view of the optic nerve, too.
New Getter Robo's Sociopathic Hero Jin Hayato deals with one of his dissenting henchmen by slashing his eyes out with his razor-sharp fingernails.
Thanks to Gohei Takeda shooting a bullet into his eye, Akakabuto's nervous system gets damaged and the bear becomes incapable of hibernating in winter. This leads to him becoming insane and somehow also causes him to grow to enormous size by the time for the final battle. Also, during said battle, Akatora sacrifices himself to put out Akakabuto's other eye.
Speaking of Akatora, he also loses his other eye during the final battle. In the manga, the exact reason is not shown, but in the anime, Akakabuto is the one who puts it out with a swipe of his paw.
The mother bear Daisuke and Gin fight gets one of the boy's arrows through her eye.
A flashback shows Kurotora losing his eye thanks to a hungry weasel's bite.
Kurojaki learns the hard way that running with a scythe in your mouth is not the best of ideas when, thanks to Gin, said scythe gets stuck in its owner's eye.
Kisaragi puts out Terry's eye during their battle, blinding the dog since he was missing one eye to begin with. In the anime, Kisaragi simply takes a swipe at Terry's face with his claws, but in the manga, you can actually see two of his toes go inside the eye socket.
In the wolf arc of the manga, Mukonga gets a bone of one his former victims stuck in his eye. He, too, only had one eye as it was and thus became blind.
In Gintama, Housen gets a cigarette holder to the eye.
God Child: Volume 6 has the Scold's Birdle chapters where girls are infected with parasites that collect around the eyeballs after a month of incubation. The eyeballs burst, and the parasites die at contact to oxygen, so to prevent losing specimen Dr. Jezebel and Cassian make sure to cut the eyes out of the (usually still alive) girls.
In Gungrave Brandon Heat takes a bullet point-blank in his left eye, and is killed. He gets better... ish... when he is revived as the gunslinging techno-zombie Beyond the Grave. Although he still doesn't get his eye back.
The eponymous girls from Gunslinger Girl are extremely resilient to physical attacks, to the point that they can't be shot down by just a few bullets. Their only true weak point is their eyes, which gets addressed in a rather gruesome way in Elsa's story, when she gets fed up with her handler Lauro's extreme neglection, shoots him dead, and then commits suicide by shooting herself in an eye.
A fact that the professional assassin Pinocchio also seems to understand, as demonstrated when he attempts to finish his fight with Triela by shoving a key through her right eye. More incredibly, Triela counters (and kills) him by stabbing her fingers through his throat.
And again invoked when right before dying, Jose kills Henrietta via shooting her in the eye.
There is a manga adaptation of Hamlet where Ophelia swings her locket at Hamlet, catching him in the eye and leaving it horrifically bloodshot for the rest of the story. It does make for a neat bit of symbolism.
In Hell Teacher Nube, the local Ojou is possessed by an obake that takes the form of a monstrous eye erupting from her hand. She tries to remove it by using this trope and stabbing it out. Unfortunately, not only does it keep growing back, the monster takes over her body more and more, extending the eyes all over her.
A flashback shows a young Seras putting a fork through the eye of an assailant. Zorin Blitz, who forced her to re-experience that memory presses her eyes against her scythe's blade afterward, brutally slashing both eyes. Seras gets better.
The scene with Jan Valentine in Ultimate Hellsing OVA 2. During his infamous "I highly recommend pissing yourselves, followed by a course of praying to your impotent God!" spiel, he places his thumb atop the eye of the decapitated head he's playing with and presses down hard causing the eyeball to burst and blood to shoot out.
It actually happens at least once per OVA to the point that it's become a Running Gag. Whenever Alucard shoots his opponents in the head or impales them, we're treated to a nice shot of their eyeballs flying out of the sockets.
In the first chapter of High School Of The Dead Takashi saves his friend who was being attacked by one of them by slamming the thing on the top of the head so hard with his baseball bat that one of its eyes get knocked out of its head and falls to the ground.
In Higurashi: When They Cry there's a scene where Rena beats Rina to death with a lead pipe. We don't see the actual beating but after Rina dies the camera pans over her mutilated face to reveal that one of her eyeballs was smashed. Another scene had Rika spray Shion in the eyes with pepper spray.
Used in the Matsuribayashi-hen manga when a young orphan girl ( Miyo Takano's best friend Erika) gets her eye punctured by a chicken while being tortured in the Orphanage of Fear.
Also, it's revealed that the incident that caused Keiichi and his family to move into Hinamizawa was him snapping after all the school bullying he went through, starting to shoot passer-bies with a model gun, and then shooting a little girl in the eye.
The villain of Hunter × Hunter: Phantom Rogue steals human eyes for his collection of dolls. He does this through nen, so there's no blood, and only dolls or (briefly) corpses are shown with empty sockets, but the way his power creeps into a victim's eyes is clearly meant to evoke this. Plus, the idea that one (later two) of the main characters spends the entire movie wandering around with their eyes plucked out is very unsettling.
In Ikki Tousen, Kakuton (Xiahou Dun) loses an eye thanks to the assassin Koushaji (Hu Che Er), when he was fighting her to protect his friend and leader Sousou (Cao Cao) and she spits a needle into his eye. Sousou goes SO apeshit at this that his Superpowered Evil Side takes control and bloodily kills Koushaji by crushing her head against a wall.
InuYasha has more than one invocatuion of this trope:
Kaede was subjected to this when she was a little girl, and this had already happened before her sister Kikyou's death. The anime and the manga difer on how this happened: in the first the culprit is Kikyo's old rival Tsubaki, while in the latter it's implied Inuyasha's attack was responsible. Now that she's a Cool Old Lady, she covers her empty socket with an Eyepatch of Power.
Inuyasha has a portal that leads to his father's grave in his pupil, which Sesshomaru decides to pull out in order to use it. In the anime, Sesshoumaru grabs Inuyasha in a Neck Lift and forcibly pours his magic into a screaming Inu's eye to dig out the black pearl sealing it. In the manga, on the other hand, Sesshomaru does it the good old-fashioned way by stabbing him in the same eye and taking out the pearl with his fingernails (Good Thing You Can Heal).
In the arc dealing with Tsubaki the Dark Miko, there is more than one eye-related injury. When Kagome deflects an attack from Tsubaki's snake familiar with her bow, it's absorbed into a screaming Tsubaki's left eye, and soon it's shown that Kikyou once did exactly the same to her in their fight for the right to hold the Shikon Jewel. And in the anime, not only does Tsubaki merge with a powerful unsealed demon via having it enter her body through her eye, but when Naraku gets fed up and sends one of his insects to collect Tsubaki's Shikon shards, it's done via having said insect pass through her head, collect the shard, and then leave through Tsubaki's eye. OUCH.
There are several examples in Part 3 as well: the possessed nurse in Kakyoin's introduction arc, Silver Chariot's opening salvo on Devo, and N'Doul's incapacitation of Kakyoin.
In Part 2, Wham/Wam/Waam/Whamuu damages his own eyes so he'll take a fight more seriously. He can regenerate them, being a super-vampire, although he never gets a chance to before he's killed.
In Part 4, Hazamada attempts to do this to Josuke with his Stand ability. It doesn't work, but it would have if the wound had been just a few millimeters deeper (previously, Hazemada inflict this to his ex-friends only because has argued with him).
In Part 8, Josuke (a different one, it's complicated) uses his Stand to steal Joshu's eyesight. While the intent is to make Joshu blind, what results is Joshu's eyes exploding. He gets better.
In Kaiji, the titular character at one point has to bet an eye or an ear in a card game. This is accomplished by way of a small machine with a tiny drill that attaches over the organ in question — every time he loses, the drill point will move a little bit closer... This would be bad enough, but the animation does us the questionable favor of explaining this by graphically animating, in cross-section, how the drill would move in and destroy his eye! Perhaps unsurprisingly, Kaiji chooses to bet his ear instead. (Then we're treated to repeated graphic demonstrations of how it would destroy his ear, just in case we weren't traumatized enough yet.)
In the fourth movie, where Shiki crushes her eyes when her mind cannot handle Eyes of Death Perception. She also tries to do it again another time, but is stopped. She got better.
In the fifth movie "Paradox Spiral": near the beginning, when Enjou Tomoe beats off a delinquent chasing him by shoving a thumb through his eye, and near the end, a scene... which probably shouldn't be described for reasons of Squick.
And in the seventh movie, Mikiya is attacked by Rio with a knife wound to his face, losing his left eye in the process. He got better despite losing his eye; Rio intended to kill him after all.
In the anime series Karas, the main character gets his sword broken, and small shards of it goes into his eyes. And it all happens in a zoomed-in slow-motion shot.
Karneval: One chapter had a Varuga that went around collecting people's eyes (i.e. ripping them out of people's heads). He tries to do the same to Nai, but the latter is saved by a sheep.
Rokudo Mukuro from Katekyo Hitman Reborn! jams his finger into his right eye to activate the Fifth Path, the State of Humans. Apparently, he recovers.
Also, during their fight together, after Mukuro pretends that what was lunging at Tsuna was just an illusion, he quickly reveals that it was actually a stone after smashing it into Tsuna's eye area in order to catch him off guard and attempt to possess his body.
In Kill la Kill, when Uzu Sanageyama realizes that he relied too much on his sight fighting Ryuko, he has his eyelids sewn shut to correct this "mistake". He takes the stitches off almost at the end of the series.
Before his death, Isshin Matoi manages to take Nui Harime's eye out.
Kongoh Bancho: Iai Bancho cuts his eyes so he won't have to see his immodestly-dressed female opponents. It makes about as much sense in-context as it sounds, but judge for yourself.
In an early chapter of The Kurosagi Corpse Delivery Service, the gang runs afoul of a crooked insurance agent who kills people with probability, and who suffers a Karmic Death from getting stabbed in the eye with a screw that fell off a passing airplane. A story arc in Volume 4 involves a parasite that infects certain species of snail mutating to infect humans as well, causing the victim's eyes to swell grotesquely and bulge out of their eye sockets. A later villain in Volume 13 ends up annoying a fertility goddess, who causes a tree to grow from inside his body and branches to sprout out of his head through his eye holes.
During one battle in Legend of Galactic Heroes, several scenes depicting the brutality of war are shown. In one case, a man is killed by an explosion in his ship, and we are treated to a visual of his eyes boiling and subsequently bursting. Pleasant stuff.
In episode 63, Olivier Poplin hurls a hypodermic syringe straight into the eye of a Terraist doctor while he and his companions are trapped on Earth.
One of the suggested methods for dealing with an intruder in Litchi Hikari Club was to put out his eyes. As this was highly symbolic, it was approved. Much later the reader discovers that Litchi's eyes were donated from Niko and Dafu, explaining the scar and the eyepatch respectively.
Alluded to in Loveless when Seimei plucks out not one, but both of Ritsu's eyes.
It's made worse when we learn that he did it to write 'RITSUKA I'M BACK' on the wall...with the blood from the eyeballs.
And in chapter 81 or something like that, some random dude tears out one of his eyes, and then afterwards sits there smoking a cigarette with blood streaming down his face.
When confronted by Mai, Natsuki and Midori in a late Mai-HiME episode after Yukariko's Wounded Gazelle Gambit, local Dark Magical Girl Nao Yuuki catches a stinger right into her left eye from her own CHILD, Julia. After pulling out the stinger, she notices her hand covered in blood, and gets extremelypissed off.
Mazinger Z: In the Mazinger vs Great General of Darkness feature, Kouji shot Mazinger's drilling missiles right in the eye of a Mykene Warrior Beast. The tiny missiles drilled through its eye and exploded inside its brain, and the monster screamed in pain as it happened. Ouch. And in another episode, Sayaka blew up with her Humongous MechaTorpedo Tits the only weak points of the Mechanical Beast Gumbina M5… its eyes. Double ouch.
Medaka Box: Kumagawa calmly blinds Zenkichi with two fingers. Then he heals the eyes.... but not the eyesight.
It is later revealed in episode 7 of season 2 that Allelujah didn't lost his right eye, he was actually hit in the forehead and the reason he covered his right eye was because of the blood flowing. His Alter ego is just "sleeping".
Though but one of the many gruesome, horrifying things that the mushi from Mushishi can do to your body, but the author seems to have a special love of strange things living in, feeding off, or bursting out of peoples' eyes. (Thematically, this may be linked to the fact that mushi are Invisible to Normals.) Just be glad that they don't exist. Maybe.
The author admits that eye trauma freaks her out, hence the giant blob of stuff oozing out of a little girl's eyes, a blind singer's eyes crawling away! and Ginko's eye being eaten by a powerful mushi which will eventually claim the rest of him.
In Naruto Kishimoto is a BIG fan of the trope, as well as eye transplants. To start, we have the part where Itachi uses the Tsukoyomi to simulate popping Sasuke's eye out of its socket. He freaking PLUCKED IT OUT.
In the anime, it's not pretty either. You see Sasuke's eye slowly bulge out of its socket as Itachi removes it. Thank GOD for the Gory Discretion Shot. That said, we get the same thing with Izuna and Madara, only Sasuke gets splattered with Izuna's blood. Nice.
Madara Uchiha actually stabs out his own brother's eyes in order to transplant them into his own eye sockets to counteract the effects of his Deadly Upgrade.
In chapter 551 this is how Itachi nullifies the Rinnegan's "shared vision" ability: By throwing kunai into the eyes of Nagato's summoned creatures.
Kakashi Gaiden: Kakashi got his one Sharingan eye when his old, regular eye was damaged in a fight, and Obito, after getting mortally wounded and recently unlocking his Sharingan, has Rin surgically replace Kakashi's with one of his while they're both conscious.
Pain tried to kill Kakashi by shooting a nail into his eye. It didn't work.
Also, in a final act of defiance against Madara, Danzo destroyed Shisui's Sharingan eye which he had implanted to prevent Madara from using it. This was thankfully offscreen.
In chapter 590 in Itachi's memory after Shisui says Danzou stole his right eye he literally takes out his other eye and gives it to Itachi to prevent Danzou from having it.
The last but not least example: in The Last: Naruto the Movie, Big Bad Toneri (who already is eye-less) rips out the eyes of Hinata's little sister Hanabi, so he can use them to activate the Tenseigan after marrying Hinata. Fortunately, Hinata rips the stolen eyes off him and gives them back to her sister.
Boruto: Naruto the Movie has an unusual example due to the Big Bad having a Rinnegan in each hand in addition to the two Byakugan and forehead Rinnegan on his face, and only the eye in his right hand is stabbed because the heroes needed to get past its ninjutsu absorbing abilities.
Ninja Scroll: This is the result when Jubei determines that Tessai is not quite “hard as rock all over.”
Xerxes Break in Pandora Hearts has one eye. The other one was ripped out by the Will of The Abyss and put in someone else's head. In addition to witnessing this event with no detail spared, he is sometimes seen scratching at his empty eye socket in moments of extreme mental or physical stress, to the point of drawing lots of blood.
Vincent has a scissors and eyeballs motif going there too. Usually Vincent's just stabbing stuffed animals' eyes out (along with necks, stomachs, etc.). There was that one time, however, that he decided to screw with Alice and jab his scissors into her pet cat's eyes. This eventually leads to the first example; Break's eye was meant for her cat.
Perfect Blue: The corpses of each murder victim are shown to have their eyes gouged out. One man is killed from being stabbed in the eye and his crotch followed by repeated stabbing all over his body.
In The Prince of Tennis, what prompted Tachibana's jump from Knight Templar to The Atoner was him hitting his best friend Chitose in the eye and almost making him completely lose sight in it. We also have Ryoma getting hit in the eye with the handle of his own broken racket, and later Fuji playing almost blind against Kirihara.
In Princess Mononoke, when Ashitaka's village is threatened by a boar-demon covered in big wriggly tentacles, he at first tries to reason with it. When said demon starts charging toward his little sister, he puts an arrow directly into the monster's eye, shown in close-up. The inhuman scream it lets out when the arrow makes contact accurately sums up the feelings of the audience.
In Project ARMS, Kei's ARMS are for her eyes. This means that when she was a child, she went through a horrible accident that involved having her eyes put out, made slightly less traumatic probably because the ARMS completely mimicked her old set of eyes (in the manga her eyes were stabbed out by a psychotic murderer and in the anime they were burned out while she and some kids tried to escape a burning building).
In chapter 96 of Psyren it's revealed why Grana has the Eyepatch of Power. Miroku gouged it out in their fight as his finishing move.
In Rurouni Kenshin, Usui of the Jupon Gatana was blinded in his back-story when Shishio slashed him across the eyes during a fight; this, in turn, led to Usui developing his extremely refined sense of hearing and becoming a Handicapped Badass. Also, in a filler arc, Shura the pirate punched her first mate in the eye when he tried to seduce her and wouldn't take no for an answer; the first mate subsequently wore an eye-patch and led most of the crew to revolt against Shura. In Shin Kyoto Hen, Chou loses an eye when Kenshin stabs him there with his sword-scabbard.
Something similar to the Saiyukiexample above happens when Cygnus Hyoga allows/begs Kraken Isaac to hit his eye... since Isaac lost an eye because of him, after getting impaled through it with a stalactite while saving Hyoga's life.
During the anime's rendition of the Galactic Tournament, right before his death Black Cygnus took off the swan ornament from his helmet and crushed it to send information to his boss (a still not Heel Face Turned Ikki). In the manga, he plucked one of his eyes instead.
Cho Hakkai from Saiyuki plucked out his own eye (almost both of them) and offered it to the relative of a youkai whose eyes he had gouged out during the mass murder he committed.
We're not sure about the extent of the damage yet, but in the last chapter of Saiyuki Reload, Ukoku apparently had his eyes shot out.
In the climax of the Sengoku Basara anime (first season), Nobunaga performs a Neck Lift on Masamune using only his palm under Masamune's neck and threatens to jam his thumb into Masamune's remaining eye. Honda Tadakatsu interferes before he can go through with it, however.
Sgt. Frog: Kululu gets drills for eyes in the infamous drill episode.
Violent fight comic Shamo is chock full of cringe-inducing, vision-averting Eye Scream moments, including how Ryo Narushima won a qualifying match, as well as how a later seen character made himself blind. The worst part? No weapons assisted in these blinding moments, just fingers and toes involved.
In the Shigurui manga, Irako Seigen gets slashed across the eyes (no spoiler because that's how he was shown in the first chapter). At first you just see a line across the bridge of his nose; then it starts to bleed, with clear fluid coming out of the cuts in his eyes. Then it gets really freaky.
In SHUFFLE!, as a child, Kaede is seen standing at the top of a flight of stairs and coldly orders Rin to pick up some writing utensils she had dropped at the bottom. Rin busies himself with the task so he doesn't notice when Kaede secretly takes out a boxcutter, stretches her arm out and (somehow) drops it directly above Rin. Rin looks up at the moment when the knife comes careening down and it slices his right eye. He gets better.
Subverted. Sakuragi elbows Hanagata in the side of his head and breaks his glasses, but doesn't damage his eyes. As much, Hanagata gets a cut on his forehead.
Played straighter later, when Minami hits Rukawa in the head and causes him to play half-blind.
In Souten Kouro We have this nice scene of Xiahou Dun losing his eye. He pulled the arrow along with his eyeball and then ATE HIS OWN EYE! Two for the price of one!
Made scarier by the fact that Xiahou Dun allegedly did that when he lost his eye in Real Life. Hope it's just a legend.
Saiga Tatsumi of Speed Grapher has a love for photography which develops into a sexual fetishism. While investigating a secret club where rich and influent people meet to fulfill their most perverted desires, he received a kiss from Kagura and developed the ability to explode whoever and whatever he photographs - Death by Photo. When using his powers his camera gains a black aura, while his right eye (it can be either, but he aims with his right) turns blood shot and the iris bright green while large veins protrude around it. Also, during his final battle with Suitengu, he is ultimately unable to defeat Suitengu before going blind from overusing his power.
In Texhnolyze, Ichise gets poked in the eye in the first episode by a women who hired him for sexual services, causing him to defend himself using his fists.Unfortunately for him, that woman belongs to a major criminal organisation, which retaliates by cutting off two of his limbs.
Shape-ified Hal also suffers one of these when he betrays Shinji. You don't see the actual injury, but you hear it.
Yamori stabbing Kaneki in the eye with a needle to make him more vulnerable to torture.
Furuta using his comrade as a meat shield and jabbing Matsumae's eyes out with his fingers.
Kaneki gets first his left eye, and then his right, taken out by Investigator Kishou Arima. Kaneki promptly has a meltdown after the first blow and it only gets worse as the fight progressed. And why is it especially vicious? Because Arima doesn't just stab out Kaneki's left eye; he stabs Kaneki from behind, through his brain.
In the sequel, Kaneki stabbing Kanae in the eye with a pipe.
Also from the sequel, Eto sewing Kanae's eyes open.
After Takizawa gets through with Sasaki, his upper face is a bloody mess. It's probably better that there's so much blood that it isn't clear what exactly was done to him.
After being captured and imprisoned in Cochlea, the amnesiac Ghoul #240 is seen wearing bandages over his eyes. This is because he repeatedly clawed his own eyes out, to the extent the wounds kept getting infected.
Furuta attempts to gouge out Sasaki's/Kaneki's eyes with his thumbs in chapter 70.
In chapter 74 of re Arima thrusts IXA at Kaneki's eyes, and asks if this is what he wants.
In Tokyo Tribe 2, this happens to Renkon Chef in episode 6 when Jadakings bites his eye off and spits it out.
In episode 17 of the Umineko: When They Cry anime Jessica blames her aunt Eva for the death of Krauss and Natsuhi, her parents. Eva gets defensive and accuses Jessica and Battler of killing her son George. Jessica gets pissed off at Eva's accusation and yells "I'll kill you! I'll kill you!" at her. Eva gets scared and fires a shot from her rifle and the fire from the discharge injures Jessica's eyes.
In the 4rth arc, Eva (or better said, Eva-Beatrice in her form) has a shot gun and threatens Ange with it. Then said gun blows up and destroys Eva's upper face, and she screams and rolls on the floor in utter pain as she covers her destroyed eyes and bleeds all over. Ange has to Mercy Kill her.
In the first volume of the yaoi manga Under Grand Hotel Sen defends himself against a rapist by poking the guy's eye out with a cross necklace he won in a checker game from Swordfish.
In Vampire Hunter D when D breaks into Count Magnus Lee's hideout he tosses a knife into his eye, Magnus casually takes out the knife, pulls his eye out of his socket, and places it back in after healing it.
Vinland Saga: As part of the carnage in chapter 92, a guy is shown with his eyes cut out; later on, another character gets stabbed in the eye, complete with fluid gushing out and his opponent digging his knuckle into the socket.
Yu-Gi-Oh! has a somewhat famous example in Maximillion Pegasus (Pegasus J. Crawford, in Japan). Throughout most of the Duelist Kingdom arc, Pegasus possesses the Millennium Eye, which takes the place of his own left eye. He wasn't born with it... the 4Kids dub removes the blood, but keeps a silhouetted introduction process, right along with Pegasus's agonized screams. At the end of Duelist Kingdom, Bakura rips the Millenium Eye out of Pegasus's head. In the manga, he gives him one of Pegasus's own replica Millenium eyes; not that it does him much good, Bakura having killed Pegasus in the process and all. The Movie later had Pegasus show Kaiba what can only be assumed to be an empty socket or the dummy eye, and we get to see Kaiba squirm in response.
In Yu-Gi-Oh! GX, there are two examples. Jim Cook has one of his eyes replaced by the Orichalcum Eye (though it's done in a discretion shot, it is implied he smashed his original eye out falling into a river. The second one involves Yubel. When Juudai's memories of their past return, his present self hovers over Yubel as she's being worked on by whoever is managing the transformation. It's made fairly clear they're removing or changing her eyes to be the magical ones they are in the present. The viewer isn't actually shown what happens, but Juudai winces at whatever it is he sees.
Played with in Hiei's case. His Jagan Eye transplant, which is a Third Eye in the middle of his forehead, is described as being the most intense, excruciating pain he's ever felt in his entire life. It seems the process involves a drill like machine burrowing into the patient's forehead, then implanting the Jagan, which then proceeds to absorb an assload of the patient's energy.
Doctor gets a jar of acid thrown in his eye in the Chapter Black saga
Played straight with King Yomi, who during a battle in his past had both of his eyes slashed by swords at close range at the orders of his then-partner Kurama, who was pissed off at him for being a Leeroy Jenkins. Ouch! Luckily, he managed to wound his assailant with an accidental stab, thus saving himself from death; he later grows into a massive Handicapped Badass, with a super developed sense of hearing.