In Cube Zero Canadian actor Michael Riley is completely hamming it up as Jax, the main bad guy the controllers upstairs send down. He's basically an over-the-top caricature who just revels in his evil and is clearly enjoying himself thoroughly.
Colin Farrell's scene-chewing role as Bullseye in Daredevil (2003) takes this trope and just runs with it to its funniest extent.
The Dark Knight Trilogy: Although there were quite sober villains (such as the softly spoken Ra's al Ghul or the deadly serious Two-Face); The Joker and Bane, however, are conspicuous for their peculiar eccentricities:
The Dark Knight: Between laughing, gesturing, and grand speeches; The Joker's presence is exceptionally over-the-top and grandiloquent, at least by the standards of your ordinary Nolan antagonist.
The Dark Knight Rises: Bane, mainly during his public speeches. It also helps to see that everything he's saying are Blatant Lies and he doesn't believe a word of them. It's almost as if he's mocking the very people he's trying to agitate.
Downfall: Hitler, who's going on a movie-long Villainous Breakdown. "THAT WAS AN ORDER! STEINER'S ASSAULT WAS AN ORDER!'' Who do you think you are to disobey an order I give?! So this is what it has come to... The military has been lying to me... Everyone has been lying to me, even the SS!"
Baron Vladimir Harkonen from Frank Herbert's Dune is already listed below under Literature, but Kenneth McMillan's portrayal in David Lynch's adaptation is so insanely over-the-top it deserves an extra mention.
"Ha-ta-ta-ta-ta-ta" "Myyyyyyyy DESTINNNYYYY!" "You can run your Ladyship, but YOU'LL NEVER RUN FAR ENOUGH!" "Let their blood RAAAAIIIIIN FRROOOMMMM THE SKKKKKAAAAHHHHHHH!"
The first two acts of Enemy Mine have No Antagonist and deal with the main characters working together to survive being marooned on a Death World. We do get an actual villain much later in the movie in the form of Stubbs, a vicious and brutal slavedriver who makes up for lost time by being cartoonishly over-the-top evil, and shouts almost every line through a huge mouthful of scenery.
Face/Off: Castor Troy, whether played by Nicolas Cage or John Travolta, is a being made of pure ham, jumping from memetically insane grins, creepily sexy comments, and dramatic one-liners within an instant. Troy is a terrorist who does things For the Evulz and to be as ridiculous as possible. Admittedly there's a bit of Ham-to-Ham Combat going on in the film, but Castor Troy is still at least a level above his rival Sean Archer in terms of hamminess.
"You Fool!! You fail to realize that, with your armor gone, my ship will tear through yours like tissue paper."
"Prepare a tear-harness! For the Female."
The Doctor from G.I. Joe: The Rise of Cobra. Even before he becomes Cobra Commander, he had his hammy moments, as Joseph Gordon-Levitt puts in a weird voice and spouts overly dramatic lines to compensate the mask in his face.
The Hobbit has Smaug, much like in the source material. Along with overly dramatic dialogue lifted from the book, he's voiced by Benedict Cumberbatch. Going further than the book he manages to some theatrical gestures, despite being a giant snake-like creature with no hands, like Circling Monologue and shows off his sheer size in the most show-offy way he can.
Darwin Mayflower: If da Vinci were alive today, he'd be eating microwave sushi, naked, in the back of a Cadillac with the both of us! History! Tradition! Culture! Are not concepts! These are trophies I keep in my den as paperweights!
In The Hunger Games: Mockingjay Part 1, Snow's conversation with Katniss doesn't involve him shouting or gesticulating or anything like that, but now that he's dropped his facade, his stoic expression and soft monotone have been replaced with openly evil sneering and sadism.
In Jack the Giant Slayer Stanley Tucci is in non-stop ham mode as Roderick. For the giants, being hammy is almost a requirement.
Aeetes, the Sorcerous Overlord of the nation of Colchis in the 1963 Jason and the Argonauts. Jack Gwillim probably never ate a single thing ever again, he devoured the scenery.
Aeetes: DESTROY THEM! KILL! KILL, KILL, KILL THEM ALLLLLLLLLLLL!
This trope is seen in a nutshell in the famous "I am the law!" scene in Judge Dredd. The good guy spits out the ultra-hammy "You betrayed the law!", and just to show that evil goes one step further, the bad guy responds with an even louder and hammier "LAAAWW!".
Eve Mauro clearly relishes her role as the psychotic Morgan in Killer Dream Home.
"This house will be mine." "Looks like we have moles all over the place, don't we? Guess I'm going to have to bury them." "I refuse to entertain your husband's lapdog." "He was going to leave this house to me when he died. I loved him, and he left everything to his selfish wife. And now you're trying to take what's mine!"
During the climax Morgan outlines an elaborate and utterly barmy frame-up plot.
"It is going to be the affair of the century. Hot blonde Bliss Leary gets caught banging boss Josh. Wavy jules goes wild, ends up bashing hubby's head in with a hammer. Then kills anxious neighbour before strangling Miss Bliss to her untimely death."
In The Last Airbender, Commander Zhao, played by Aasif Mandvi. Averted with Fire Lord Ozai, who is somewhat of a Large Ham in the original cartoon but is soft-spoken and contemplative in the film.
Given that Mad Max is a World of Ham, virtually all the villains fit this. The warlords of Mad Max: Fury Road deliberately exploit this, along with their Conspicuous Consumption, to come across as larger than life to their fanatically devoted followers, who in turn work themselves into a frenzy and commit suicidal acts in order to impress them.
Then there's Ultron, who is Tony Stark turned into an evil robot, along with uncannily puppet-like exaggerated movements and even singing a Disney song.
Honestly, it's easier to name the Big Bads who aren't hammy. The Winter Soldier is fairly low key and has barely any lines in the movie (the only time he's Suddenly Shouting, it's played for drama), Alexander Pierce is a Soft-Spoken Sadist and Helmut Zemo never raises his voice above slightly loud as he's a soldier on a revenge quest, he's not a cackling villain. The Vulture is understated, except when yelling at his sidekicks. Yellowjacket only has a few hammy lines once in full costume, and everyone in Ant-Man and the Wasp is subtle, in contrast to the movie being outlandish.
The franchise's Greater-Scope Villain Thanos manages to ham without even talking in his scene in The Stinger of The Avengers'. It only goes up from there when he actually gets a speaking role in Guardians of the Galaxy. And then Avengers: Infinity War is basically two hours of Thanos showing off no one can be as grandiose as him.
As soon as Mysterio is revealed as a bad guy, he drops the serious façade he had built for a cheerfully smug personality, with subsequent interactions with Spider-Man in particular getting very theatrical.
Dreykov, a Fat Bastard who wants to taunt, gloat and overall be the biggest presence in the room.
Pam Ferris as The Trunchbull in Matilda devours the scenery with so much aplomb you have to wonder if that's her real Trademark Favorite Food rather than chocolate cake.
Freddy Krueger in the later A Nightmare on Elm Street films, as he started to have more fun tormenting his victims and became a theatrical wisecracker.
Whenever someone gets possessed in Night of the Demons (1988) and its sequels, you can bet they'll start chewing the scenery as well as faces.
The Wicked Witch of the West in Oz the Great and Powerful is supposed to be terrifying, but instead, she is incredibly hammy, complete with Narm and Scenery Chewing.
In The Pink Panther Strikes Again, Dreyfus seems fully aware that he has turned into a Bond villain and he is clearly loving every minute of it.
In Power Rangers, Rita is clearly having a lot of fun being evil. It especially stands out in this Darker and Edgier, more 'grounded' version. Everyone else is more subdued, more angsty, even characters who were a lot hammier originally. Alpha goes from an excitable worrywart to a Deadpan Snarker, and Zack goes from a quippy, show-offy Dance Battler to a brooding loner. Meanwhile, every scene of Rita's is every bit as much scenery-chewing fun as the original.
The hamminess is been disputed between Jellon Lamb (John Hurt), who drunkenly chews every piece of the bar's scenery, and the Burns family led by Arthur (Danny Huston) in The Proposition. Then Arthur kills Lamb for trying to kill Charlie, leaving the hammy niche to him.
Rhys Wakefield as the "Polite Leader" of the gang trying to invade Ethan Hawke's house in The Purge. Right away, he gives a Slasher Smile similar to the one in his mask and continues mugging while speaking in an Affably Evil tone that just shows he's full of himself.
Retroactive: The murderous Frank, as played by Jim Belushi, is constantly cracking bad jokes and chewing up the scenery around him.
Christopher Lee occasionally indulges in this. Although fully capable of being subtle and understated, he knows what's expected of him. His performance in The Return of Captain Invincible especially showcases this.
In Scanners II: The New Order, The Dragon Peter Drak is by far the most melodramatic of the villains, gleefully killing people with his mind and laughing about it afterwards. By contrast, during his most evil act (murdering David's elderly mother for no reason) he is deliberately calm and quiet.
Cristal Connors in Showgirls is one of the hammiest characters in this film from her campy mannerisms and lines to her strange obsession with doggy chow. And she is the main antagonist, besides Andrew Carver. In fact, this was very much intentional as her actress Gina Gershon admitted that she was campy on purpose, once she realized just what kind of film she was making.
Jim Carrey as Dr. Robotnik in Sonic the Hedgehog. He's clearly having the time of his life bringing Robotnik to the big screen, combining his penchant for loud and manic characters with the already bombastic nature of the source character. Whether it's him dancing while preparing his vehicles, to screaming about his love of lattes with steamed Austrian goat milk, his portrayal is definitely one to be remembered. Then there's the moment Robotnik has a Freak Out, complete with exaggerated movements after Sonic destroys his robots on the highway.
The Green Goblin. You can't really go subtle when you're flying around dressed as a green storybook monster, and Willem Dafoe wisely didn't bother.
"I've watched you from deep behind Norman's cowardly eyes. Struggling to have everything you want, while the world tries to make you choose. Gods don't have to choose. We take."
Whenever Doctor Octopus tries to be menacing, he talks as hammily as possible.
"Find him. Or I'll peel the flesh off her bones..." (while a tentacle opens and closes akin to a biting gesture)
Eddie Brock after bonding with the Venom symbiote.
"Ooh, my Spider-Sense is tingling, if you get what I talking about. Tiger."
The later Venom solo movie takes it one step further, with the symbiote itself spouting evil phrases in a cavernous voice, and Tom Hardy even adding in weird acting moments playing Eddie Brock to show it's contagious, like a parasite (PARASITE?!!!!). And its sequel brings in two hammy villains on its own, Carnage and his lover Shriek.
Star Trek VI: The Undiscovered Country: the Shakespeare-spewing General Chang, to the point where he actually spins around in his chair while yelling "Cry havoc and let slip the dogs of war!!" in the midst of battle. Dr. McCoy lampshades it:
Dr. McCoy: I'd give real money if he'd shut up.
Star Wars: Palpatine/Sidious is notably hamtastic in Revenge of the Sith after his secret Sith identity is revealed. Other villains who fit this trope include General Grievous, Darth Vader, and Darth Maul (the latter two of which are moreso Cold Hams).
M. Bison in Street Fighter, OF COURSE!!!. He's a tinpot wannabe dictator supervillain who makes several grandiose speeches about his plans to conquer the world, makes Chun-Li's attempted revenge fall flat with his But for Me, It Was Tuesday retort, and in the climax, he finally loses it completely and declares himself a god while flying around his base shooting electricity at Colonel Guile. Raúl Juliá certainly gave himself a DELICIOUS send-off. (Sagat is also a ham; he just pales in comparison to Bison.)
90% of Tim Curry's roles fall under this. If he's playing a villain, there's a good chance it'll be an awesomely hammy performance. Tim Curry does not know any other way to act other than completely over the top, chewing every piece of scenery in sight. And we love him for it.
Almost every villain in TRON: Legacy is a Large Ham (with the exception of Rinzler), but especially the Big Bad. CLU uses his hamminess to make our world open and available to all of his programs. Yes! TO ALL OF THEM!!! And that's before you get to his agent, Zuse, who chews the scenery with his Bowie-esque nature. A yin and yang of hams, if you think about it.
Virtuosity has a young Russell Crowe as villain SID 6.7, a virtual assassin who once in the real world is having fun like nobody cares. One scene even has a criminal psychologist noting he likes to show off, "like a child to its parents".
Komodo, oh dear sweet Komodo from Warriors of Virtue. The man is a giant ham and cheese sandwich, as these clips prove.
Magneto, played by Ian McKellen, has a few moments of this, but he's calm the rest of the time. His younger self, portrayed by Michael Fassbender, also overacts whenever he's overtly threatening.
