- Creator Backlash: Screenwriter Alexander Payne disowned the finished film, saying that Adam Sandler changed too much of his and Jim Taylor's script from a tasteful Black Comedy about homophobia into something "offensive, homophobic, and generally stupid." He even unsuccessfully attempted to get his name removed from the credits.
- Creator Couple: Adam Sandler's wife Jackie appears as the school teacher when Larry goes to his daughter's career day.
- Executive Meddling:
- Mid-Development Genre Shift: The original script was planned as more of a Black Comedy with more sincere socio-political commentary on homophobia and gay marriage. After Adam Sandler signed on, he rewrote it to downplay all of the social commentary and be more of a generic buddy comedy.
- Real-Life Relative: Steve Buscemi was actually a New York City Firefighter before he became an actor. His brother is an actor, Michael Buscemi, who plays a firefighter — "Higgy" in the credits, "Higgins" on his uniform.
- Wag the Director: Dan Aykroyd approached Adam Sandler and respectfully requested to change some of his lines. Sandler thought the material Aykroyd came up with was hilarious, so he was allowed to do so.
- What Could Have Been
- When the film was in production in its original Black Comedy form, Tom Shadyac was attached to direct, with Will Smith and Nicolas Cage or James Gandolfini as the leads. Budget issues resulted in this version falling through.
- At one point, the film was considered for a Vince Vaughn and Owen Wilson vehicle.
- Working Title: I Now Pronounce You Joe and Benny
Trivia / I Now Pronounce You Chuck and Larry