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- In Fruits Basket, Tohru regrets not saying "take care" before her mother left on the day she died. She had pulled an all-nighter for a test and simply couldn't wake up when Kyouko went to work...
- There's the implication that she feels responsible for her death. She said it everyday, except for the day her mom died...
- In Bleach, Orihime regretted not giving her brother Sora her usual fond farewell when he left for work on the day he died because they had an argument earlier. When Sora came back as a Hollow and was defeated/purified by Ichigo and Rukia, Orihime took the chance to say farewell to his departing spirit.
Orihime: "Brother... Have a nice day!"
- In Digimon Adventure 02, a very young Ken Ichijouji yelled at his older brother Osamu that he wished he'd disappear. The same day, Osamu was hit by a car...
- In Attack on Titan, shortly before Wall Maria is breached and the Titans enter his hometown, Eren has an argument with his mother Carla about wanting to join the Survey Corps. Minutes later, he is forced not just to flee, but to leave the seriously injured Carla behind to be devoured by a Titan lest they would all perish. He bitterly regrets spending his final moments with Carla having a foolish argument, while furiously vowing to eradicate the Titans.
- Elfen Lied: Kohta's last words to his little sister Kanae were a threat that he'd "hate her forever" unless she apologized to his friend Lucy, who Kanae had just accused of murdering people at the festival they were at. He then sees her bifurcated in front of him... by Lucy herself. He shows clear regret in present times for fighting with her just before she died... although the trauma of witnessing such a thing resulted in repressed memories, so he's convinced himself for much of the series that his little sister actually died of a long illness, and feels regret for not being nicer to her in general.
- In Your Lie in April, Kousei's last words to his abusive and ill mother were that he wanted her dead. His guilt over it is an important part of the trauma that keeps him from playing piano.
- A varation occurs in Yakitate!! Japan, where Pierrot spends a few moments ranting about his parents, who had abandoned him as a baby, while drinking with the King of Monaco, not realizing that the King is his father. When he finally realized that he was essentially insulting his father in his face, the latter passed away before he could apologize. Made even worse when Pierrot found out that Daddy Had a Good Reason for Abandoning You and that his father died a Heroic Sacrifice to save his life.
- Implied in Tokyo Ghoul: in their last conversation, Touka got into a fist-fight with Kaneki and concluded by calling him "trash" and telling him not to come back to Anteiku. Soon afterwards, Anteiku is raided by CCG and Kaneki is defeated by Arima, with his ultimate fate ambiguous.
- Victor Alvarez the second Powerman after Luke Cage gave up the name has this in his origin story. Victor's parents were getting ready to divorce, and Victor was upset that his dad wasn't trying harder to make the marriage work. Victor accused his father of not being strong enough to fight for his own family. When Victor saw how much his words hurt his dad, he immediately tried to apologize... and that's when the bombs Bullseye set in Hell's Kitchen exploded. Victor survived by somehow absorbing chi from the other victims, including one of Iron Fist's students but he could never forget his dad's wounded expression.
- One Batman story had a flashback that showed 8 year old Bruce getting angry at his parents for some reason and saying that he hated them. In an effort to cheer up Bruce, his parents took him to watch Zorro the very next night. Bruce was about to apologize to them on the way home right when they entered Crime Alley...
- Inverted in Runaways with Gertrude Yorkes' death. Chase Stein was about to be sacrificed to the Gibborim by Geoffrey Wilder when Gert showed up and bluntly informed Wilder that Chase was a selfish, cheating bastard whose death was unlikely to earn Wilder any points with the Gibborim. So Wilder killed Gert instead, and Chase was left wondering if Gert truly meant what she'd said.
- In pre-New 52 continuity, the last words of Slade Wilson's oldest friend and Battle Butler Wintergreen when Slade who was possessed by a maddened Jericho at the time though Wintergreen didn't know that murdered him were "well, I suppose it was only a matter of time." After being freed of Jericho, Slade was haunted by those words, realizing that his closest friend genuinely expected Slade to murder him someday.
- Soul Chess: "Look if you want to go and get yourself killed that's fine by me. Don't expect me to be at your funeral." -Shinji Hirako to Hiyori
- In the Katawa Shoujo fic Second Beats, Hanako is implied to have faced this fear when Hisao suffers a heart attack immediately after the events of her bad ending, in which she tells him she hates him for pitying her.
- In the Gensokyo 20XX Series, we have this a couple of times. In 20XXI, we have it where Eirin commits suicide and the other characters wishing they didn't treat her as badly, with Ran explicitly wishing she didn't say what she said to her. Later in 20XXV, we have it where Yume Ni dies of illness, in the aftermath Chen's "Reason You Suck" Speech, leaving the latter very upset and wishing she could have taken it back and never let that be the last thing she's said to her.
Chen: The last thing I said to her wasn't "I love you" or anything to the effect, the last thing I had said to her was so scathing that it had broken her will and I wish I could take it back.
- From Kill la Kill AU, A Broken Heart, an Untold Story, and a Sister's Regret, Nui and Satsuki has a fight while Ryuuko (who's narrating) was a asleep and it ends with a guilt-ridden Satsuki running away. From what is made clear later, it had something to do with the fact Ragyou almost died giving birth to Satsuki, something in which she regrets later, especially when she actually learns to truth about what happened at the time her sister was born and when she has this pointed out to her, leading to her to go to Sagamihara to look for her, which lands her in the hospital for injuries. However, this is subverted in that Satsuki doesn't die, actually, she is just fine, as she had just run away.
Ryuuko (to Nui): You had better watch what you say to people 'cause it could be the last thing they've heard! If we don't find Sats and or get a call from the morgue, then she will have died remembering what you've said to her!
- Blood and Spirit: As revealed in a flashback, the last thing Terminus ever said to Hylia before she cast off her divinity was a condemnation of her decision to become a mortal for the sake of being reborn alongside her chosen hero as foolish. She only comes to truly understand why Hylia did so after losing her own hero, whom she had fallen in love with, to Majora, and regrets her final words to her sister to this day.
- Averted in Raindrops, as before she dies, Ryuuko tells Satsuki that she loved her and Satsuki responds in turn, enabling the two sisters to part on rather bittersweet terms.
- In Guardian, Lulu snaps at Yuna just before departing on her second pilgrimage—as her sole intention was to save Yuna from going on one herself, and Yuna was too eager to listen to Lulu's patient explanations for why she couldn't join her. Lulu is instantly aware of this and says on the next page that her last goodbye to her sister-figure may have been to yell at her.
- Finding Nemo: The last words Nemo says to his Overprotective Dad Marlin are the words "I hate you." before he is suddenly taken by divers.
- Ice Age 4: Continental Drift After her father embarrasses her in front of all the teen Mammoths, Peaches furiously states to Manny "I wish you weren't my father!". Shortly afterwards, the continent plates divides and separate Manny, Sid, and Diego away from Ellie and Peaches. As the iceberg holding her father drifts from the view, Peaches sobs and blames herself for getting separated from her father since the last thing they did was argue.
Manny: STAY ALIVE! No matter how long it takes, I WILL FIND YOU!
Peaches (sobbing): Mom, this is all my fault! If I had just—
Ellie: Peaches, this is NOT your fault. Okay?
Peaches: What if I never see him again? And the last thing we did was fight!
Ellie: Hey, your father is the toughest, most stubborn mammoth I've ever met! He'll come back for us. (wraps her trunk around Peaches) That's a promise.
- A variant, seeing as no one dies, but in The Wild Thornberrys Movie, Eliza laments that the last thing she said to Darwin before her ability to talk to animals was taken away was "Darwin, for once in your life can you just stop talking!?"
- In The Karate Kid (2010), Mr. Han recalls he was arguing with his family before they died. He doesn't remember what it was about, but he hopes it was important.
- In the first Spider-Man film, Peter laments the argument he had with Uncle Ben, just hours before Uncle Ben gets shot.
"I can't help thinking about...the last thing I said to him. He tried to tell me something important, and I threw it in his face."
Uncle Ben: You're a lot like your father. You really are, Peter, and that's a good thing. But your father lived by a philosophy, a principle really. He believed that...that if you could do good things for other people, you had a moral obligation to do those things. That's what at stake here. Not a choice, responsibility.
- In particular, the very last thing he said to Uncle Ben before he was shot, was yelling at him to stop pretending to be his father... something which visibly upset Ben. This actually comes back at the end of the movie in a more redeeming way.
Norman Osborn: I've been like a father to you... be a son to me now.
Peter: I have a father. His name was Ben Parker.
- In The Amazing Spider-Man:
Peter: That is nice. That's really...that's great. That's all well and good, so where is he?
Uncle Ben: What?
Peter: Where is he? Where's my dad? He didn't think it was his responsibility to be here and tell me this himself?
Uncle Ben: Oh, come on! How dare you?
Peter: How dare I? How dare you?!
- In particular, the very last thing he said to Uncle Ben before he was shot, was yelling at him to stop pretending to be his father... something which visibly upset Ben. This actually comes back at the end of the movie in a more redeeming way.
- In Upstream Color, a man is revealed to be constantly rehashing the last words he had with his wife before she lapsed into a coma. She was trying to reconcile, but he was angry and dismissive.
- In Forrest Gump, In Vietnam after Forrest carries a heavily wounded Bubba to safety.
Narration: If I’d a known this was gonna be the last time me and Bubba was gonna talk, I’d a thought of something better to say.Forrest: Hey Bubba...Bubba: Hey Forrest. Forrest, why'd this happen?Forrest: You got shot.
- A subtle version in Thor: The Dark World: Loki tells Frigga that she's not really his mother. That is the last time he ever sees her. He doesn't even get an invitation to her funeral. It's slightly alleviated by the fact both of them knew he didn't mean any of it, but it still clearly tore him apart and shows when Thor comes for him.
- In Avengers: Age of Ultron, Pietro Kill Steals Clint's robots and him casually insults him, calling him a slow old man. Clint half-heartedly draw his bow in his general direction, muttering "Nobody would suspect a thing... 'Last I saw him he was under a robot. Yes, such a great loss...'". Then at the climax, after Clint had prepared to use his body as an Human shield, in order to save an innocent child, only for Pietro to dive in front of both of them at the last second. The look in Clint's eyes said it all.
- Jurassic Park III: When Dr. Grant discovers that Billy stole a set of Velociraptor eggs for the sake of funding their research, he gives him a scathing "The Reason You Suck" Speech, outright telling Billy that he's "no better than the people that built this place." Shortly afterwards, Billy pulls off a Heroic Sacrifice to save Eric from a flock of hungry Pteranodons, and Grant is shown regretting that that was the last thing he said to him.
- In Harry Potter and the Goblet of Fire, after Harry and the Weasley children have a brush with Death Eaters, Mrs. Weasley mentions that she'd never forgive herself if Fred and George had died when the last time they'd talked she was chewing them out for their bad grades.
- A variation of this happens in the A Series of Unfortunate Events second book the Reptile Room when the night before Dr. Montgomery's murder the Baudelaires are too preoccupied trying to guess Count Olaf's plan to tell him anything after the movie. The following morning when they see his corpse, Violet feels guilty for never getting to say thank you for the movie and tries to remember if at least they said it earlier.
- In The Shattering Prelude to Cataclysm, Thrall, while leaving for Outland, finds his old friend Cairne Bloodhoof waiting for him, who bitterly complains about his choice of Garrosh as Warchief. The two have an argument, and Thrall's last words are telling his friend that he has made his decision and it's up to him whether he helps Garrosh or undermines the Horde by being stubborn. Thrall considers apologizing, but the next thing he hears about Cairne is his death, which is partly Garrosh's fault.
- In The Last Guardian, book 8 of the Artemis Fowl series, as Foaly is racing to save his wife, he tries desperately to remember his last words to her. He thinks it was "I love you", but he isn't sure. Fortunately, he's able to save her.
- In If I Stay, Adam broke up with Mia before the crash because she couldn't promise to spend New Years the next year with him. When he finally talks to her in the hospital, he's in tears.
- The businessman in Station Eleven who didn't get to speak to his family at all before the outbreak; the last phone call he ever made was a meaningless business call full of corporate jargon.
- In Divergent, the last thing that Tris says to Al is that if he comes near her again, she'll kill him. He commits suicide the evening after, and Tris wonders if she was too hard on him.
- Bruce Coville's The Ghost Let Go has a young woman whose last words to her mother where "I HATE YOU!", before the mother and the girl's boyfriend (the cause of the argument) were killed in a car crash, while the girl was horribly disfigured. The regret at those words, and the fact that ghosts can't communicate with the living (except the protagonists), is what is causing them to stay, hence the title.
- In Burn Notice, Fiona and her sister had a fight before her sister was killed in a shooting and she's always regretted it. Her sister's death motivated her to join the IRA.
- Inverted in How I Met Your Mother. After Marshall's dad dies, his family decides to have the funeral eulogies based around the last words he said to each of them. Marshall gets distressed because the last thing his dad said to him was that he should rent Crocodile Dundee 3, whereas everyone else has profound, meaningful moments to talk about. But then it turns out there was a rather touching message waiting for Marshall on his voicemail... And he still goes with the Crocodile Dundee story when talking at the funeral.
- An episode of Home Improvement has Jill telling her father that she was too sick for him to visit. He dies shortly thereafter, and the rest of the episode focuses on how Jill regrets lying to him and not being able to spend his last moments with him.
- The George Lopez Show:
- There is a tear-jerking scene where Angie remembers that the last time she spoke to her mother before her death, she said she would never forgive her for cheating on her father and called her a "selfish tramp".
- Parodied in "The Trouble with Ricky", where he blames Ricky for the burning of his garage and bemoans the "death" of his golf clubs, saying that the last words to his lucky putter were "I hate you".
- In Criminal Minds, Elle's father died when she was eight and the last thing she said to him was "I hate you, Daddy!" (she was angry that he didn't have time to teach her to ride her bike). Years later, she still regrets this.
- Cold Case:
- In the episode Disco Inferno, the father of the murder victim the detectives investigate confesses to this, for the last words he said to his son, in reaction to said son's future life choice, were "I... renounce... you." The son died later that night.
- In the episode "Shuffle, Ball Change", the victim and his brother got into a shoving match that resulted in the brother injuring his knee, possibly derailing his wrestling career. Their infuriated father told the victim, "God help you, Maurice". The boy disappeared soon afterwards, leaving the father thoroughly haunted by the thought that his son had run away from home thinking that his father hated him, and even more torn up when he learned that his son had in fact been murdered, and that either way, those were the last words that he said to him.
- In That '70s Show, Red's mother dies as Eric is driving her home. Because she was being a heartless crow (like usual), no one had anything good to say about her, but were still heartbroken when she was gone.
Red: I didn't say "I love you," or even "See you later." No, the last thing I said to her was "Show me tail lights."Eric: ...Dad, the last thing I said to Grandma was "It wouldn't kill you to be nice once in a while." But I guess it did, because then she died.
- In 8 Simple Rules, the last thing that Bridget said to her father before he died was "I hate you."
- Played for Laughs in Community when the group worries that Pierce is dead after he's late for a meeting:
Troy: Oh, man, the last thing I said to him was 'suck it'.Britta: Me too.
- In the season 3 premiere of The Borgias, Rodrigo is dying of poison (although he eventually pulls through), and Lucrezia feels guilty because the last thing she said to him was that she was glad her brother Juan (Rodrigo's favorite) was dead.
- Supernatural: Bobby became a hunter after his wife, Karen, was possessed by a demon, but what really eats at him is the last conversation they had.
"Biggest regret of my life, this fight. You’d think it was when I had to stab her to death, but...no. All through that - I was thinking we never got to get past this. If I’d have known, I’d have said anything she wanted to hear."
- Invoked by Phil on Modern Family to get Claire to tell the truth. As he falls asleep before his surgery he points out that the dangers and says "And if I never wake up, I'd hate for the last thing you ever said to me to be a lie".
- A late episode of Barney Miller depicts the murder of Mr. Cotterman, a recurring guest star throughout the series. A stunned Det. Harris says he can't even remember if he'd said goodbye to the man or wished him well when he last saw him. (For the record, he did.)
- One episode of Law & Order: Special Victims Unit features Munch confessing that he told his dad that he hated his guts just before his dad committed suicide. Naturally, he regrets this.
- In Dead Like Me, Joy's last words to George before her daughter's death are (in response to George's comment about "those are funeral clothes"): "There's going to be a funeral if you don't get your ass out of bed! Now move it!" George even remarks in the narration, "Boy, is she going to be sorry." Joy does regret being so hard on George.
- Daredevil: One of Frank Castle's final moments with his daughter was refusing to read her favorite book to her before bed. She was killed by criminals the following night:
Castle: I said, "No, Daddy's too tired, see. But I...I'll read to you tomorrow night." I'll read to you tomorrow night. I promised.
- The song "The Last Thing She Said" is all about this trope, except that the woman with regrets is actually the one in danger of dying.
- Adventures in Odyssey: After her boyfriend Mitch is killed during the Novacom Saga Connie spends part of an episode trying to remember what the last thing she said to him was, believing that it was "probably something really stupid". She also expresses regret for not telling Eugene how much she cared for him as her best friend before he and his wife went on the run from Andromeda. At the end of the episode she talks about this with Whit, who tells her that they have to trust that "God will fill in the blanks for all the things we should have said"; Connie counters that they shouldn't expect Him to before telling Whit that she loves him.
- The World Ends with You: Eri regrets not being able to apologize to her friend Shiki before her death; she had offended Shiki by telling her she wasn't meant to be a designer, when she meant she was much better as a seamstress. Shiki, playing the Reaper's Game, was listening as Eri told someone about this, and hearing this renews her resolve to win the game and see Eri again.
- Late in one route of Blaze Union, Siskier and Jenon playfully make fun of each other while rescuing Distressed Dude King Ordene before splitting up in hopes of getting him out of danger faster, culminating in Siskier calling Jenon an idiot. Jenon winds up gravely injured, then falling into and being washed away by the castle waterways. Siskier discusses this with protagonist Garlot while the two are trying to find Jenon later on.
- Inverted in Osu! Tatakae! Ouendan with the song "Over the Distance". While no doubt the lady regrets the big fight see had with her loved one before he died, the story takes the perspective of the ghost, who was given a chance to contact her one last time to apologize.
- In Fire Emblem Awakening, during the Bad Future, a girl named Severa and her Action Mom Cordelia have an argument about Cordelia's thoughts on her First Love, Chrom. In the height of the fight, Severa accuses Cordelia of not loving her father enough and still being hung up on Chrom, and isn't convinced even when Cordelia tells her it's not true... The day later, Cordelia dies in battle. And Severa never forgives herself for that.
- Final Fantasy XIII: In their last conversation, Lightning chewed Serah out for expecting her to believe her story about becoming a l'Cie and harshly drove her out of the house. The next time they see each other, Serah crystallizes in Lightning's arms before the latter can actually apologize.
Lightning: Serah... I should have listened to you.
- In Get Medieval, Asher spends the whole story arc regretting that his last words to his girlfriend before ending up stranded on medieval Earth were to tell her to buy cat food.
- In this Buttersafe comic, a sailor realizes ahead of time that this is the last time he'll ever see Claire, and somehow he still manages to screw up his goodbye.
- The Simpsons:
- Ned Flanders regrets that the last thing he said to Maude was "No footlongs."
- Implied with Homer and his mother Mona. During Mona's final appearance, Homer blew up at Mona for never being there for him and putting her various agendas ahead of him. Later that night, Homer cooled down and made an apology card for her. Only to find that she died sometime in the night.
- Marge once worries that her last words to Homer would be "Clip your toenails; they look like Fritos!".
- In the 500th episode, when the family is going to the bomb shelter for an emergency drill, Homer says if anyone has to fart, do it now. When Marge asks what if those were his last words, he replies that his last words will be "I can outrun that lion!".
- In the first episode of the twenty-sixth season, Rabbi Krustofsky's last words to his son Krusty before dying are "I always thought you were just ehh..." This sends Krusty into a deep depression.
- In Gargoyles, after Demona (apparently) sacrifices herself to save Angela, the daughter she had just recently met, Angela immediately regrets that the last thing she said to her was that she hated her.
- In Batman Beyond, Terry bitterly regrets his last conversation with his father:
"I yelled at him, Mom. He grounded me and I wouldn't listen. The things I said—!"
- Batman: The Brave and the Bold has Bruce himself being bratty on Christmas Morning after getting his father's nutcracker soldier instead of a "Swashbuckler" toy. His parents bring him to the "Swashbuckler" movie and he still refuses to lighten up. Doesn't take a genius to think of what happens next...
- In the God, the Devil and Bob episode "Bob's Father" Bob visits his father in the hospital and just as Bob's leaving the room his father imitates the flatline noise as a joke just to see how he would react. Bob angrily tells him he can go to Hell and his father dies a second later. Initially Bob is afraid that just by saying that he condemned him to Hell, but God tells him it doesn't work that way. Later God arranges one last meeting between Bob and his father so they can part on better terms.
- Jerrica from Jem has some regrets about acting mean towards her mother the day she died in an airplane crash. She didn't even properly say goodbye to her because she was upset.
- Referenced in this article published December 15, 2012, the day after the mass shooting at Sandy Hook elementary school, in which the author describes how she made a vow that the last words that she said to her children before going to bed at night would always be "I love you," and encourages others to do the same.
Hey! Get back in your bed. I love you
- Mike Starr, the former bassist of Alice in Chains, admitted to having this during his appearance on Celebrity Rehab. He told those in attendance, which included Layne Staley's mother, that the last time he talked to Layne, he urged him to call 911 due to his ailing condition from drug use. Layne refused, and this sparked an argument that ended with Starr storming out. As he left, he heard Layne call out to him "Not like this, don't leave like this." Since Layne is believed to have died the next day, this was the last conversation they had. Starr blamed himself for Layne's death until he died nearly a decade later in 2011.
- Waylon Jennings lost a coin flip with Buddy Holly, and was forced to take a bus to Minnesota while Holly took a plane. When Holly joked "Well, I hope your ol' bus freezes up." Jennings joked back "Well, I hope your ol' plane crashes." Tragically, the plane did crash, killing everyone aboard. Waylon was haunted by those words for the rest of his life.
- Many Nintendo fans suffered this and a case of My God, What Have I Done? after Satoru Iwata passed away on July 11, 2015. Their last communication with him was anger and disappointment towards Nintendo's E3 2015 presentation, which included the divisive Metroid Prime: Federation Force. Iwata apologized and promised next year would be better. He never got the chance to do it and many fans are now upset that this was the last thing they said to him before he died.