Sonic: You know if it weren't for my awesome touchdowns you guys wouldn't have gotten away with it so... where's my Gatorade dunk?
Earthworm Jim: I got your dunk right here.(Zip)
Sonic: What are you talkin abou—Nooooo!
"When you're in Las Vegas and eat chicken Caesar salad, and find out that it gives you the shits, but you're stuck walking the strip and almost crapped behind some bushes, then you run into a casino and bust down the stall door, and SHIT ALL OVER THE PLAAAAAACE!"
Sonic and Tails trying to destroy the Alien Queen that turns out to be Alf. Tails keeps on being attacked by Facehuggers while Sonic keeps on trying to find food. And gets jealous when Tails gets attacked.
Two Words: Destroy Venom
Tails listening to Gangman Style.
Eggman deep-frying a wallet and then eating it.
Soniqua herself on top of an arwing. Also, "AVOTACO!"
We also get this dialogue after Frank the Worm dies.
Tails (Still listening to Gangnam Style and sees that Frank's Arwing got destroyed): HOLY SHIT!!! Hey you guys better not be going to Espacios Tacos Locos!
"EGGMAN RUSH!" ....it's all the Zerg can say...
"Dryin' and dyin'!!"
Sonic killing Sparkster out of annoyance for his inconsistent sequels.
Pig Soldier: Yaaaaaay!
Sonic tries to stop himself from having children with Lucca, so what does he do? Call Eggman to dress up as Sonic.
Lucca: "Hurry up Sonic, I'm waiting for you!"
Eggman: "I'm on my way, *sticks head out of the door* sugar tits!
Due to time travel, the president is Princess Potato.
Sonic: Oh sweet! Bacon, Egg, and Cheese!! ...Oh, and BJs!
Tails: Hey!! Get away from there!! THAT'S MY PISS JAR!!
Sonic: Oh my god! Kathleen Turner ate Eggman! You crazy bitch!
The taco sandwich. Two tacos for bread, and between that, ten tacos.
The Butterfly Effect in action.
Crash: Whatever that fatty fat Eggman did in the past made me the most popular thing since Torn-Apart-With-Your-Hands-Bread!
Sonic: You mean sliced bread?
Crash: What is a, "sliced bread"?
Gilius Thunderhead posing as Sonic. Sonic challenges Thunderhead to prove he's the real Sonic by spindashing, but Thunderhead thinks that it involves "tripping on bath salts and dry-humping J.C. Penney mannequins".
Sonic fooling Mario's initial hitmen that Eggman is Sonic.
Eggman believing that there is food. His expression is priceless.
Sonic turning into Wario in "Things Get Messy".
Lucca's "new" child. Eggman says "that is one ugly little kid". (The child has Eggman's face and wears underwear).
Sonic and Co getting high from the Toejam and Earl hallucination is funnier than the first time.
Eggman's reaction to the idea of rebuilding the entire world using his shit.
Eggman: "This sounds smart. Hm. I like this."
When a pixel appears out of nowhere because Sonic called for help, Eggman asks for a sandwich. Sonic says he has to be sensible, and asks for fifty kajillion pixels.
One particular scene from "Kung Fu" stands out - Kirby comes to the place to live a life of peace. Sonic and Tails talk him into killing just one guy. The altercation happens offscreen, and when it cuts back the place is filled with blood and guts, with Sonic and Tails staring in disbelief.