While all of the main characters on the series indulge from time to time, "Doc" Hartford of the Galaxy Rangers could practically license his snark as a deadly weapon. Even the AI "Tweakers" he created are sarcastic.
Doc:(while jailed up in a dungeon) Dear Miss Etiquette. I'm a Galaxy Ranger with a serious problem. I'm about to be executed on a distant planet, and I have no idea about the proper attire. Can you advise me? Signed, Embarrassed.
Simon in the 1980s cartoon version of Alvin and the Chipmunks, though very subtly in The Alvin Show then when the 80’s series came around, got deadpan snarkier as the series went on, from occasionally snarky in the first couple of seasons to practically every response being sarcastic.
Tyrone from The Backyardigans plays this role both audibly and more often visually. Somehow, despite him not wearing pants, he manages to give the impression he's slouching with his hands stuck in his pockets.
(from "To the Center of the Earth", after Tyrone loses his penny a second time because of Uniqua's invention) Tyrone: See? I could have just walked over to get it. Now it's lost! Professors Uniqua & Pablo: Poppycock! Inventions are always the way! Tyrone: The way to drop my penny.
Jen from Downtown is this almost all of the time. She also gets the aforementioned deconstruction, admitting that her constant sarcasm comes from her own insecurities, and that the reason she picks on Alex the most is because he's her best friend.
Ben: So... you're my father's receptionist. You know, I mean, in a way, we're sort of related, you and I, like siblings or something, because we both work for my Dad. I mean, you're his receptionist, and I'm his son. So, you know, fantastic, super. Laura: Could you go now?
Though quite a few characters engaged in snark on Dungeons & Dragons, it was a particular specialty of Eric's: "Now why didn't I think of that? A game of patty-cake will stop an army of raging orcs any day!"
Norm the Genie from The Fairly OddParents.Every sentence is a Deadpan Snark. In the episode "Back to the Norm", Norm teams up with Crocker and constantly Deadpan Snarks him. An example is when Crocker is doing his trademark "FAIRY GOD-PARENTS!" spazzing, and Norm makes him hold a chocolate shake in a glass container. When Crocker finishes, Norm says, "That's how I like my shakes. Spazzed, not stirred." From the same episode, Norm asks Crocker, "That thing on your neck...is that your ear?"
Brian and Stewie from Family Guy, but especially Brian.
Brian: What's it called?
Brian: Wow, a song named after a girl. There aren't a million of those already.
Sometimes Stewie manages to outsnark Brian, though.
Brian: I didn't even know I even had a son until today, and besides, it's not like Tracey ever asked for my help.
Stewie: Yeah, it seemed like they were all set without you, she's done a fine job creating a child-friendly environmen-ta-re-mi-ooh, buh de buh boo, buh buh buh THPTHPTHPTHPT...
Pip in Kerwhizz is a voiceless example, growling in frustration at Ninki's wrong answers.
Shego from Kim Possible. In fact, she considers Drakken to be little more than mocking gold.
Shego: Okay, let's get Plan Too-Complicated-To-Actually-Work over with. ... Drakken: Would it hurt you to show a little enthusiasm? Shego:(deadpan) Woohoo, extra hoo. Happy? ... Shego: Y'know, for someone who's supposedly a mad genius, I'm not seeing much of the "genius". Dr. Drakken: Keep it up Shego, and you'll see plenty of the "mad". Shego: Ooh, scary man.
Fun-fact: Shego wasn't originally planned to be like this, but after the directors realized how much talent her voice actress had in doing the Deadpan Snarker, they changed her whole script.
Kim herself also has her moments.
Also Monkey Fist.
Monkey Fist(said menacingly to a child-hostage staring at him): "Take a picture. It'll last longer."
In the show Liberty's Kids, both Sarah and James switch off in playing this role. More often than not, it's James snarking about how stuffy the high society that Sarah was born into is. Though Sarah has been known to throw a great deal of snark right back at him about how infantile Americans in general — and James specifically — can be.
Cutman: Almost got him! Protoman: "Almost" only counts in horseshoes, Cutman.
Jamie from Megas XLR is, while being a strong coward and womanizer, a decent example of the trope. He is often well aware of and comments on the lunacy and danger of Coop's actions and, sometimes, dialogue. That being said however, he seems to enjoy the destruction Coop's actions brings, so may or may not comment if it doesn't directly affect him.
Coop's button of doom would occasionally get in a good one. For example, it was once labeled "Do Something Stupid, Coop".
Reverend Putty, and possibly Ms. Sculptham, on Moral Orel are this. Putty because he's bitter at being a virgin and possibly annoyed at God, as judged by his "I Hate My Boss" mug.
Doyle from The Secret Saturdays. After the family finds out that the Kid Hero is the ultimate evil monster they were all trying to hunt down, the patriarch of the family forbids them to tell anyone about this.
Doyle: Yeah, I was planning on a radio jingle, but I can cancel that.
His sister is the same. But then, what else can you expect from the voice actress of Shego?
Comic Book Guy to the point where he causes a sarcasm detector to self-destruct.
Lisa often fills this role occasionally, especially when interacting with the severely less intelligent Bart and Homer. While Lisa fought for things that she believed in the earlier seasons and actual took concern in Homer or Bart's dilemmas, she has been reduced to a pure example of this in the current seasons. "Beware of My Cheating Bart" is a text book example of this◊.
Bart can also act in this role when dealing with Homer.
Deconstructed briefly in "Homerpalooza" when Homer gets up on stage to perform his newfound skill of taking cannonballs to the gut:
Teen #1: Oh, here comes that cannonball guy. He's cool.
Teen #2: Are you being sarcastic, dude?
Teen #1: I don't even know anymore...
Yoyo from Simsala Grimm is known for all sorts of sarcastic one-liners.
In the latter episodes, Stan from South Park has a habit of pinching the bridge of his nose and sigh, when other character does something stupid. He often exclaims "Dude, this is pretty fucked up right here" and, in "Child Abduction is Not Funny", he remarks to Kyle, "Dude, sometimes I think our parents are really stupid," and as they rejoin their families at the conclusion of the episode, "Jesus Christ, dude, they've done some stupid crap before, but, Jesus Christ...".
And there's Craig, who is the personification of this trope.
Craig: ''Do you guys know why nobody else in School likes hanging out with you? ... Because you are always doing stuff like this. You are always coming up with a stupid idea to do something, and then it backfired, and then you end up in some foreign country, or in outer space, or something. ... That's why nobody likes hanging out with you guys.
Craig: This is fun. Let's walk for miles through a spooky jungle. It just keeps getting better and better.
Craig: Let's see what's in there. That's why you guys get into these situations. Because when you come across a spooky, ancient ruin, you say: "Let's see what's in there."
By the end of the episode, the four becomes very annoyed with his remarks and tell him things happen you just run with it.
Even Optimus Prime gets in on this from time to time. It's sometimes hard to resist, given the state of cartoon villainy in the 80's.
"Amazing. A booby trap that actually catches boobies."
Rodimus Prime is prone to this.
Rodimus: Don't panic yet. Stay calm until we know what's going on. Then we'll panic.
It goes beyond Deadpan Snarking and straight into Gallows Humor and Black Comedy. For instance, when the Autobots and their two human allies appear to be stranded in space...
Ultra Magnus: It could be months until we're found.
Spike: Aw swell. What do Daniel and I do when the air runs out?
Rodimus: Basically you'll have two choices: suffocate or smother.
Rattrap from Transformers: Beast Wars fits this role perfectly. He is snide, cynical, and sarcastic. He's notable for his frequent use of the phrase "We're all gonna die.", and constantly bickers with Dinobot, and, later, Depth Charge. He is, however, a capable soldier and, if need be, leader.
Rattrap: Eh, command's a pain in the tail... especially with this pack of hyenas. You can keep it.
Blackarachnia, as the show's resident Dark Action Girl, also qualifies. Especially when dealing with Silverbolt.
Slapper, Gas Skunk, and Dark Scream do this a lot to their boss, Sky-Byte, in Transformers: Robots in Disguise.
(a girl who humiliated Carver is waving at him at the beach) Carver: She's waving at me? Is there a law against this kind of thing? Tino:(deadpan) Oh yeah, they're enforced by the Federal Bureau of Waving.
The main characters of W.I.T.C.H. all have their moments. Irma Lair is the resident queen of snark.
Raimundo from Xiaolin Showdown, although not exactly deadpan, is still very snarky.
Basically every teenaged hero from Young Justice- and quite a few of the adults and villains, too. Probably the most obvious ones are Artemis and Robin I/Nightwing, the latter of which will snark even in the darkest situations.