South Park: Bigger, Longer & Uncut. After the Baldwin family's home gets bombed by the Canadian Air Force, all of them are dead except for a single survivor. He triumphantly boasts "Ha ha! You missed me!" right before the last plane drops a bomb on his head as well.
Films — Live-Action:
A crooked police lieutenant to Jack Napier near Batman's beginning: "The future? You mean when you run the show? You ain't got no future, Jack!" (This culminates in an Ironic Echo at the factory, when Napier kills the lieutenant with a single shot.)
High Priestess: Mr Gorsky, when I kill, I kill for good. Gorsky: Are you threatening me? High Priestess: Bless your soul. Gorsky: You'll need a nuke to kill me! (Gorsky's security system detects an incoming missile) Gorsky: Bitch...
Alfalfa:Then the clouds opened up and God said, "I hate you, Alfalfa!"'''
Die Hard 2: The first person to be killed is the church custodian. Baker and Thompson, two of Colonel Stuart's men (disguised as airport maintenance workers) trick him into letting them into the church, and he starts musing about the current proposals to shutter the church. He says, "Yeah, I kinda feel like a piece of me is dying along with this church." Baker immediately says, "Well, you're right about that," then pulls out a pistol and shoots the custodian.
In The Film of the Book of A Clockwork Orange, Alex is being interviewed while being fed by the widower of the woman he raped in front of him. During the interview, he says, "I get the feeling something bad is going to happen." Two seconds later, he's out like a light.
In The Dark Knight, the Joker is shooting at an armored truck using handguns and a shotgun when someone on the inside remarks that he's going to need something a lot bigger to get through it. Cue the rocket launcher.
Later in that same scene, the Joker's semi and the Batpod are playing chicken when Batman fires something. The Joker says, "He missed!" — except what Batman fired was a cable, which he uses to pull a snowspeeder and jackknife the truck into the air.
Batman: One man or the entire mob? He can wait. Maroni: Some two-bit whackjob, wears a cheap purple suit and makeup. He's nobody, he's not our problem....
Though the rest of the cast are hardly innocent of this, Juno tempts fate at least five times in The Descent:
"Everything's going to be fine. Better — it's going to be great!" "You want adventure Holly, when have I ever let you down? Tomorrow's going to be awesome." "Relax, I've never been lost in my life!" "We'll be fine." "It's about us. Getting back to what we used to be."
After Sarah becomes stuck in a tight cave tunnel, Beth tries to calm her down by essentially telling her that this is the worst thing that will happen to her, and everything will be alright after she calms down and works herself free. Things get MUCH worse.
Particularly cruel of fate in this instance, as when Beth says "the worst thing that could've happened to you has already happened" it seems like she's referring to the brutal deaths of her husband and daughter. Fate looks at this poor woman and says "Nope. Better kill all of her friends too."
"Not by the hand of man shall he fall." Oh, that makes him sooo much safer. They only left out, let's see, women, children, hobbits, elves, wizards, An ear infection, giant eagles, Ents, Sauron, other Nazgûl, dragons...in short, many, many things that are more likely to kill him than a puny man and a few that aren't.
Pearl Harbor. A Japanese bomb lands next to a sailor and doesn't go off. Not realising the tiny spinning propeller at the back of the bomb is the fuse, he shouts "It's a dud... IT'S A DUD!" KA-BOOOOM!
In The Princess Bride, Westley and Buttercup are discussing the final dangers of the fire swamp:
Buttercup:(while in the Fire Swamp) Westley, what about the R.O.U.S.'s? Westley: Rodents of Unusual Size? I don't think they exist... (Westley is attacked by a R.O.U.S.)
To be fair, Wesley had already seen the R.O.U.S.'s, he was just trying to make sure Buttercup didn't freak out.
In the Cold WarAlternate History movie Red Dawn 1984, Soviet paratroopers have just landed in an American town. We see a bumper sticker saying "THEY CAN HAVE MY GUN WHEN THEY PRY IT FROM MY COLD DEAD HANDS!" The camera then moves down to the owner of the car lying dead with a Colt .45 in his hands, which is then souvenired by an enemy paratrooper.
Star Trek (2009): Scotty says he's going to beam Kirk and Spock into what he thinks is a cargo hold "where there shouldn't be anyone around". It's no surprise at all when they materialize in the midst of a control room full of armed Romulans.
Tremors: Earl and Valentine have resisted temptation (free beer) and left Perfection, Nevada for a new life. As they're driving along Valentine says, "Now there's nothing, and I mean nothing, between us and Bixby!" Seconds later, they see Edgar Deems high up on a power pylon. They stop to help him, and later events force them into a battle to the death against the Graboids.
One of the best examples is evil hacker Boris Grishenko in , who, after surviving the destruction of the Janus Base and his boss's demise, delivers his Catch Phrase "I am invincible!" — scant seconds before huge vats of liquid nitrogen decide to disgorge their contents in his direction, flash-freezing him to death on the spot.
The opening of the movie with the Dam infiltration:
Alec Trevelyan: Half of everything is luck, James. James Bond: And the other half? (alarm goes off) Alec Trevelyan: Fate.
Goldfinger. While talking to the gangsters Goldfinger boasts that "My plan is foolproof!" Not with James Bond around it isn't.
Vader saying "There'll be nothing to stop us this time!" The subsequent cut to two pathetic droids trekking through the desert hardly seems to contradict this, but...
A bit of EU information on The Empire Strikes Back has it that Admiral Ozzel, that mustached guy in the beginning, says to an aide that with the control of the Executor, he has become the ultimate power in the universe. Moments later, Vader contacts him to deliver his "letter of termination".
Caddyshack: During his Bizarre and Improbable Golf Game in the middle of a rainstorm, Bishop Pickering says to his caddy, Carl, "The Good Lord would never disrupt the best game of my life. I'm infallible, young fella!"
"I'm here! There's nothing to worry about!" Cue Tim Curry.
Lampshaded thoroughly in the first few minutes of Walk Hard:
Nate: There's nothing I won't do with this long, long life of mine... That's what's great about being young. So much time to do great things. (later) Dewey: You know how mad Pa gets when we play with his machetes. Nate: Come on. There's nothing wrong with a little machete-fighting.
The machete fight was after they played catch with live snakes and jousted on tractors.
Back To The Future Part II: The future has been saved, and Doc is trying to land the DeLorean during a very heavy lightning storm. Marty warns him to be careful: "You don't want to get struck by..." Guess what happens next.
A pretty blatant example occurs in Battlefield Baseball. The Gedo coach wonders out loud, while looking around, if there is a Worthy Opponent that was brave enough to assault his headquarters. Cue Jubeh, arriving at the scene with an explosion, followed by The Cavalry to do exactly that.
The first Resident Evil. Right after entering the code to open a door, J.D. says "See how easy that was?" Seconds later he's dragged to his death by zombies behind the door.
The raptors in Jurassic Park are contained, right? "Unless they figure out how to open doors." Guess what happens. Taken to ridiculous extremes in the Rifftrax.
Ministry of Fear (1944), the Film Noir spy movie by Fritz Lang. The Nazi spy says "You wouldn't shoot your own brother" to his sister as he escapes out the door. There's the crack of a shot and a hole appears in the door; moments later his dead body tumbles through.
The Great Race. While Max and Professor Fate are on a small iceberg, Max thinks there may be a storm.
Professor Fate: You thimble-headed gherkin, do you realize the odds against a storm in this part of the ocean at this time of year? 100-to-1. (thunder, immediately starts to rain)
Lloyd Cramden: We've just had our first break. According to this dispatch I just received, our team of agents has them cornered! At any second... (gets another message) It was a trap. We just lost another team of agents.
The Golden Child. When Jarrell is taking the test to obtain the Dagger he says, "This is a piece of cake!" Not long after that he almost falls to his death and a rope bridge explodes.
Ocean's Twelve: Tess has to bail out most of the cast by impersonating her own actress. Matt Damon's character tries to reassure her that no-one she's going to run into actually knows Julia Roberts, and the last thing anyone will be is personal. In walks Bruce Willis, As Himself. Their reactions are priceless.
In the rather bad action movie Titanic 2 someone had the brilliant idea to name a ship Titanic and set it on the same route as the original. Things get worse not too long after.
Bob Hoskins delivers the line "I tell you: this is gonna be one lovely day," just before his car gets T-boned by a garbage truck and then riddled with bullets in the movie Unleashed.
And at the end of the movie, he gives us the second instance of this trope when he has his nice car parked in an alley during the final battle, saying "This will keep her out of harm's way." Guess what happens.
Randy: Never, ever, ever, under any circumstances, say "I'll be right back." 'Cause you won't be back. Stu: I'm gettin' another beer, you want one? Randy: Yeah, sure. Stu:I'll be right back! Randy: You see, you push the laws, and you end up dead, okay? I'll see you in the kitchen with a knife.
This trope is featured prominently in the short film from the Nestle Philippines Anthology entitled Sign Seeker, where the protagonist spends the entire morning tempting fate, looking for specific "Signs" from the universe to signal to him if today is the day he will ask the girl he likes if she would like to go on a date with him. This is one of the rare, positive examples of this trope: it plays the trope straight and is still funny while NOT making the person who is tempting fate miserable in the process.
G.I. Joe: The Rise of Cobra offers a classic example of an enemy who appears to be retreating, but is actually just getting out of the way of something worse. At the climax of the rather lengthy Paris chase scene, Snake Eyes abruptly lets go of the Cobra operatives' car after hanging on to it for the entire chase.
Baroness: He gave up!
Storm Shadow: He never gives up.
WHAM! [their car gets brutally T-boned by an oncoming train]
From the first Harry Potter movie: When Harry's abusive uncle claims "there's no such thing as magic!"
Later in the same movie, when the same character claims that because it's Sunday, they're not going to have to deal with any letters. Cue several owls swarming the house and filling it with letters.
Willy Wonka and the Chocolate Factory. Grandpa Joe and Charlie are in the Fizzy Lifting Drink room. Grandpa Joe says "A swallow won't hurt us!". After they each take a swallow, they float into the air and almost get chopped to pieces by a huge exhaust fan in the ceiling. Laser-Guided Karma kicks in when it's revealed at the end that the only reason why they survived is because out of all the 5 kids, 4 of whom lost by their own vices, Charlie was the only one who refused to give Arthur Slugworth, ostensibly a rival confectioner, a sample of the Everlasting Gobstopper—and as it turns out, Slugworth was actually a Wonka employee used for this Secret Test of Character.
DEBS. While the protagonists are investigating a bank vault, Amy says "See? That wasn't so hard." Then a Trap Door opens under her, sending her down a secret underground slide.
In Paul, the statement "I doubt we'll ever see those guys again!" just ensures that 'those guys' show up at a random bar to delay our heroes as the feds are closing in. They also give one of the agents final confirmation that they're really chasing an alien.
Played with in the beginning of Raiders of the Lost Ark, when Indy and his Peruvian guide are at a temple chamber containing an ancient idol.
Satipo: There is nothing to fear here.
Indy: That's what scares me.
In Indiana Jones and the Last Crusade, Indy and his father are spying on the Nazi villains from a nearby ridge. After they notice that the Nazis have recently acquired a tank, Indy's father warns him to get behind cover before the Nazis spot him. Indy's response: "Dad, we're well out of range." Seconds later, a shot from the tank blows up the Jones's car parked a few feet away.
One of the best exchanges from Men In Black: a bad-tempered farmer named Edgar is investigating the flying saucer that just crash-landed on his pickup truck. As he peers into the smoking crater where the truck used to be, shotgun in hand, the unseen (by the audience) alien orders:
Alien: Place... projectile weapon ... on the ground.
Edgar: You can have my gun *racks shotgun* when you pry it from my cold, dead fingers.
Alien: Your proposal ... is ... acceptable. *eats him*
In Honey, We Shrunk Ourselves, Wayne and Gordon land in a bowl of dip and Gordon worries about getting eaten during a party going on in the house. Wayne assures him that "They're teenage girls, how much can they eat?". Guess what happens next.
In Juan Of The Dead, the protagonist and his band of freelance zombie-killers find themselves backed into a room by a swarm of the dead. Someone is stupid enough to ask "How can this be worse!?" which of course causes the lights to go out. Juan is understandably annoyed with the speaker.
In Film/Dogma, Azrael and his Quirky Mini Boss Squad has cornered Bethany, Jay, Silent Bob, Rufus and Serendipity in a bar and are planning to kill them. Silent Bob has the golf club he swiped from the bishop of the church they were at and, not thinking of it, Azrael tempts Silent Bob into hitting him with it, telling everyone "Please! I'm a fucking demon.". Silent Bob shrugs, winds up... and smashes in Azrael's chest in. Looking down at the gaping hole in his chest, he can only croak out "But...I'm a fucking demon..." before dying. Turns out the bishop blessed the driver so he can have a better golf game.
At the end of the second Wishmaster, the casino owner can't believe that hundreds of people just dropped dead in his establishment (the Djinn claimed their souls), causing him to say "What's next?! Frogs and locusts?!". Guess what the Djinn conjures up when the owner inadvertently makes a wish.