One episode had Meg snap at her whole family and gives the biggest "The Reason You Suck" Speech to them, blasting them for their flaws and how badly they had treated her over the years. One would think Meg finally catches a break as her family breaks down in tears from the revelation, but Meg later realizes that the reason her family treats her like shit is because they need someone to expel all their negative energy into and without Meg for that, they would turn on each other. Meg decides to apologize for what she said and lets her family abuse her again for the sake of keeping everyone slightly sane. Some fans may see this as a cheap in-universe reason for why Meg is abused in nearly every episode.
Meg's increasing and obvious Sanity Slippage. For example, she wishes she had softer voices in her head.
Or when she dated a corpse and pretended that it was still alive.
Much of the Meg-bashing. Face it, it sucks to be her!
Some episodes depict her dabbling into Self Harm, probably as a result of all of the abuse.
All of the times Peter's gotten raped. It's quite disturbing.
Some of the collateral damage and injuries during the Giant Chicken fights. Many civilians get injured or killed. One of the later fights has the chicken, in this order: falling from a great height and getting strangled by a chain. Luckily for him, the chain breaks... which leads to him falling and getting impaled through the ass by a giant spike, which then bursts out through his neck!You'd think that be enough, but no. The spike bends, putting the chicken's body next to a rocket engine, which activates, essentially cooking him. Finally, in the aftermath, we see the chicken's impaled, cooked corpse floating through the ocean.... and his eyes open. At THIS point, the viewer actually feels sympathy for the chicken, because regardless of his feud with Peter, he didn't deserve what he just went through.
The one from Yug Ylimaf begins with Brian and Stewie looking at all the damage after the plane crashed, before the reverse Giant Chicken fight.
Stewie: My God, look at all this devastation!
Brian: What the Hell happened?
Pre-Cancellation: Seasons 1- 3
The "Super-Griffins" segment of Viewer Mail #1, due to the implied and outright stated amount of collateral damage. In short, NEVER give any of the Griffins super-powers. Unless it's Meg.
The post-apocalyptic episode, Da Boom. The whole episode was scary, especially where Stewie mutates into a head with octopus arms, then lays eggs, which hatch into MORE Stewie heads with octopus arms, that take over the town.
Stewie nightmare about being kidnapped by Santa in "A Very Special Family Guy Freakin' Christmas".
The inside of Stewie's mouth at near the end of "Mind Over Murder".
Being a parody of Poltergeist, the episode Petergeist had some genuinely disturbing moments, such as when Peter starts shaving, parts of his face start falling off in bloody chunks, then his face morphs into Hank Hill and he says: "Hehehe, propane."
From "Barely Legal," Joe is training Peter, Glenn, and Cleveland to be cops. They are locked in a room together, Joe, who can see them through the window, says: "One of you is on PCP. In a few seconds, one of you will go completely insane." Quagmire calmly looks at his wrist, and says nonchalantly: "Ugh... How'd all this skin get on here?" and proceeds to RIP THE SKIN OFF OF HIS HAND as Peter and Cleveland scream bloody murder.
Meg's obsession over Brian, which led to her kidnapping him and trying to seduce him.
The ending of "Chick Cancer." Stewie killing Olivia and Victor by fire?
Season 6Season 7
A minor one in Road to Germany, where Brian and Stewie travelled back in time to find Mort and are attending the wedding of one of Mort's ancestors. As the (Jewish) music plays the scene switches between happy wedding guests dancing with the couple and the Nazis rolling out tanks and aircraft ready to begin attacking Poland. Then the bombing starts and the music stops, the dancers stop and look at the doors. It's just... creepy...
In the subplot of "Quagmire's Baby", Stewie creates a retarded clone of himself (dubbed Bitch-Stewie). Later, he creates a "Bitch-Brian" even more dumb than "Bitch-Stewie." At the end of the episode, both clones slowly begin to decay— Bitch-Brian loses his jaw, and his upper stair of teeth— gums too. And Bitch-Stewie has an eyeball hanging out. Suddenly, Bitch-Brian melts extremely graphically, with his muscles and bones visible (the bones melt too). And Bitch-Stewie melts, too. Afterwards, Brian comments he has an urge to lick the bloody puddle of ex-clones.
In "Dog Gone", Brian unties a dog, which then viciously attacks and kills a smaller dog before being shot to death by cops. Not before biting one of the cops in the neck. The fact that there are dogs like that in Real Life just makes it worse.
Stewie: I think that's why it was tied up.
Stewie's head injury in Brian Griffin's House of Payne. He is unconscious, his brain is visible, starts to rot, even a raccoon starts mauling it.
"The Splendid Source", since it was based off a short story, is pretty dark and unusual. One moment that stands out is when the gang is caught by The Men in Black and have burlap sacks put over their heads while The Men in Black whack them unconscious with their guns.
Also, when Peter stabs Cleveland with a pencil (and Cleveland returning the favor a bit later).
Brian & Stewie has Brian and Stewie getting drunk on scotch. Then Stewie asks Brian to pierce his left ear. However, Brian's not too careful with it and causes the ear to bleed. Then Brian says that it's too thick to go all the way through and yanks it out. Stewie's ear is open and bleeding profusely.
Brian: Oh, wow! Oh, [bleep].
Stewie: Wha-wha-wha-what is it?
Brian: There's so much blood.
This line in particular, when Brian is looking at Stewie's left ear and we see a close-up of it, with the bottom cut open:
Brian: I don't think it's gonna close.
The season 9 opener. After Lois figured out it was Diane Simmons who did it, the scene where Lois' eyes go wide and then Diane slowly tilts her head, could send shivers down anyone's spine.
In "Trading Places", Peter is prepared to go to high school armed with a gun for a parody of Columbine-style shootings. When Lois tells him to go to school as a regular kid, Peter calls a guy to tell him the shooting's off. But then we heard guns going off and people screaming on the other end. The joke is even more depressing thanks to what happened at Sandy Hook Elementary in Decemeber 2012.
Chris screaming in pain from the pain in his stomach (in reality he was experiencing the signs of a heart attack), its just unnerving to hear someone like Chris scream in that type of pain.
Santa, the elves, the reindeer from "Road to the North Pole."
Think about this; Lois's opponent in "Baby, You Knock Me Out", murdered three of her opponents in the ring and planned to make Lois her fourth victim. Let that sink in for a minute; I'm pretty sure some boxers have murdered some of their opponents in the ring in real life, and somehow went on their lives knowing they can take a life with just a few, skilled punches.
The scenes of the episode "Seahorse Seashell Party" pictured above, when Brian is hallucinating from drugs, contain the most horrible, grotesque and terrifying scenes in the history of Western Animation EVER. Among them, Stewie becoming a kind of snake-demon. After that, comes something even worse: Brian is transported to a hallucinogenic trip where everything is dark and horrible, and there observe Peter Griffin naked, tortured and roasted by monsters and demons (the image on the right, so here, draw your own conclusions), Lois twisting the head and leaving two snakes in his eyes and looking like demon in Stewie in two sequences more. The laughter makes the devil while Brian falls into a bottomless pit in hell is very disturbing too.
The explanation of James Woods' return in "Tom Tucker: The Man And His Dream", where doctors drain the life force out of a 17 year old girl into his body.
And apparently, Chris doesn't take bad news very well.
"Killer Queen" has Chris being strangled to near death. And it's not Patrick!
Plus the flashback shots of Patrick strangling fat people and his entrance to Lois and the others.
Those who were strangled at the fat camp have discolored skin, veins popping out of their necks, and their are mouths wide open (probably with looks of horror). The thing is they all had similar features like Chris, mainly blond hair.
Stewie notices the Uncanny Valley that is Queen's News of The World's Robot.
"Leggo My Meg-O". It's not suprising if you're familiar with the film it's based on.
Some parts of the climactic fight between Stewie and Penelope, including where Stewie stabs Penelope right through the arm. See the entire fight here.
Penelope giving a kid a cyanide pill.
"Amish Guy" has Peter doing the really old cartoon gag where the steam coming off a freshly baked pie forms beckoning fingers and tries to go up Peter's nose, which is supposed to draw Peter into eating the pie. When Peter refuses, the steam somehow starts ripping off Peter's clothes so it can rape him. We then see the steam is also holding Quagmire's eyes open, forcing him to watch.
Family Guy Viewer Mail 2:
The ending of the "Fatman and Robin" sketch in Family Guy Viewer Mail #2. We have a twist on the classic Midas Touch story. After made angry by a Robin Williams roast, he shouts to God that he wishes everyone was Robin Williams. He's struck by lightning, and when he wakes up in the hospital, discovers he has the power to turn whoever he touches into Robin Williams. He starts out having fun, turning his kids, Tom Tucker, various patrons at the Drunken Clam, Joe's legs, and several others into Robin Williams. Then he wakes up, and discovers that Lois has been turned into Robin Williams. He comes down to Brian for help, shaking him in panic, turning him into Robin Williams. A tea kettle he picks up gets the face of Robin Williams.. He tries to blow his brains out, the revolver turns into Robin Williams. He runs out the door (which turns into Robin Williams) running with all the Robin Williams' around, jumps in front of a car to kill himself, the car turns into Robin Williams and he's fine. He's chased by a mob of Robin Williams' to a cliff, and they're all telling jokes. He jumps and notices the large rock below him, closing his eyes and smiling, as he'll be released from this nightmare. The rock turns into Mrs. Doubtfire and he's unscathed. After convincing all but 5 Robins to leave Quahog, we cut to the Griffin's kitchen, with the Robin's dressed as Peter's family members (Stewie actually wasn't turned since he disguised himself, but Peter didn't know that) with Peter, who's hair and clothes are a mess, with a disturbed looking grin on his face.. Brian Robin asks for coffee, which Peter passes him, revealing that HE CHOPPED OFF HIS OWN HANDS, LEAVING STILL BLEEDING STUMPS. Now THAT's messed up.
Brian!Robin: Hey Peter, can you pass the coffee?
Peter:(disturbingly calm) Sure, Brian the Dog. Anything for my family.
In the "Point of Stew" segment. Brian chases a squirrel down with his car on the road. When he kills it, we see the squirrel squished and smeared all over his car tire. Just...ugh.
Stewie: He can't hurt you anymore. (closes the squirrel's eyes)
Back to the Pilot, anyone? The CG sequence in particular. Surreal animation and froggy Quagmire getting blown apart by Terminator Joe, in particular...
Plus the alternate Brian with the slit throat, and the alternate Stewie and Brian who are infused with barber poles. "This is life for some reason!"
Also the Fridge Horror that the only alternative to 9/11 in the [[FamilyGuy FG]]/[[AmericanDad AD]]/[[TheClevelandShow TCS]]-verse was apparently a second civil war going nuclear. Crapsack World, much?
Peter ripping a guy's face off in "Grumpy Old Man"
Also Stewie getting his ears impaled with knitting needless after a car crash.
In "Quagmire And Meg" the girls going crazy at the Teen Choice Awards(I.E. smashing their heads on the stage, ripping out their eyeballs) and then Wilford Brimley going on a shooting rampage with a shotgun.
For those too afraid to look, it starts out with the four of them laughing at a bad joke about dessert, which quickly follows into Laughing Mad as they're laughter becomes shriller and their eyes slightly unfocused, and then they just start taking large bites out of each other's faces without stopping their laughter.
The entire "Yug Ylimaf" episode. Brian's shenanigans with Stewie's time machine forces the flow of time to go in reverse, meaning everything that happened in the past is now going to happen once more but from the end to the beginning. At first it starts of funny, such as showing the infamous Peter VS The Giant Chicken fights and the bathtub gags with Cleveland going in reverse and the one scene where Peter, Chris, Stewie, and Brian wind up reverse vomiting. Horror sets in when Stewie realizes that with time accelerating in the backwards direction, he will be unborn! Stewie goes through his painful experiences of body development once again, which are teething (reversed so now he loses his teeth) and walking (he loses his body strength to stand up so he can no longer walk). Stewie then gets stuffed back into Lois' body as his birth scene goes backwards. If Brian hadn't fixed things, Stewie would have experienced becoming a sperm again and then all life in the world would have been non existent thanks to time reversing.
Sheldon the turtle from "Lois Comes Out of Her Shell", who messes with the family's lives before trying to kill Stewie at all costs.
Meg's heart in "Friends Without Benefits". It's on her head, which is the reason why she wears a hat all the time — though Meg has gone hatless before, and that heart was not there. What's worse is that Dr. Hartman doesn't bother doing anything about it nor does Lois beg Dr. Hartman to do something about it.
And the fire shooting the fireman before killing himself.
"Joe's Revenge" has Peter doing making a "scalding hot asphalt angel" in Mexico, which causes his back to burn and leave only muscle and backbone.
Peter: Second-degree burns, first-degree fun!
The ending to "Twelve and a Half Angry Men". Stewie says that since Mayor West was found not guilty of the murder, he says that there's a maniac still on the loose cutting peoples' power and killing them. Then the lights go off...
Stewie: We're dead.
Chris getting his face removed at the end of "Save the Clam."
"Vestigial Peter". Just the idea that Peter not only had a vestigial twin, but there's also the fact that it was fully developed and that it could talk is somehow disturbing.
"Quagmire's Quagmire" has the scene where Sonja beats Quagmire into submission with brass knuckles and locks him in the trunk of his car, intending to make him her sex slave.
Brian after he shaves himself in "A Fistful Of Meg." He looks like a real life naked mole rat. Not only that, but actually making Peter cover in fear, and then forces him into touching his nipples.
Peter: Why do you have so many nipples?! Its like touching a plastic bag filled with chicken bones!
Chris clawing out his own eyeballs after seeing the aforementioned naked Brian.
"Mental Mike" in general. A screaming, animalistic lunacy clearly capable of killing somebody whose Hair-Trigger Temper is treated dead seriously by the rest of the cast. He's basically Jeff Fecalman 2.0!
Plus the scene where Meg sends four tough guys to beat him up. Next time we see them, they're all blood-riddled corpses, and Meg sees the words "YOU'RE NEXT" written on the wall in their blood.
The bully melting after he sees Meg's boobs.
When Chris gives Meg "her back".
Peter cutting his own penis, then gives it to Brian in a package, and then appearing and laughing while bleeding in his lower parts because of the mutilation.
"Bobba-Dee Babba-Dee". When Peter announces that the family is staying in Italy forever, Stewie decides to do what Italians go and murder their brothers. Stewie then puts a garrote around Chris' neck as blood comes out.
Brian's death in "The Life of Brian" with Stewie witnessing the whole thing. Anybody whose ever lost a pet like this will probably feel very uncomfortable.
It becomes even more jarring in the sense that this episode starts off like a typical episode (with a bonding moment between Brian and Stewie, to boot, as they prepare for a game of street hockey). Mere seconds later, Brian suffers one of the most violent deaths ever seen on the show, and just like that....he is gone. The very concept that death can come so suddenly and completely snuff out a person's presence becomes more apparent when Vinny is introduced, because all you can think of at that point is that Brian, a character you've become familiar and comfortable with every time you tune into an episode of Family Guy, is gone for good.