U.S./Canadian Comics

Since the medium of comics arguably originated in the USA, it should come as no surprise that a whole lot of comics are American. Also included here are Canadian comics, as they are for the most part pretty similar to their southern counterparts due to the large amount of intermingling between the two cultures, businesses and talents, and often see distribution in both regions regardless of origin.
Companies prolific enough to have their own pages:

12-Gauge

Aardvark-Vanaheim

Abrams ComicArts

AC Comics

ACC Studios

Ace Comics (1940-1956)

  • All Love
  • All Romances
  • Andy Comics
  • Atomic War
  • Baffling Mysteries
  • Banner Comics
  • Beyond
  • Captain Courageous Comics
  • Challenge of the Unknown
  • Complete Love Magazine
  • Crime Must Pay The Penalty
  • Dotty
  • Ernie Comics
  • Four Favorites
  • Four Teeners
  • Fun Time
  • Glamorous Romances
  • The Hand of Fate
  • Hap Hazard Comics
  • Heroes of the Wild Frontier
  • Indian Braves
  • Lightning Comics
  • Love At First Sight
  • Love Experiences
  • Men Against Crime
  • Monkeyshines Comics
  • Mr. Risk
  • Our Flag Comics
  • Penalty!
  • Real-Life Secrets
  • Real Love
  • Real Secrets
  • Revealing Romances
  • Science Comics
  • Scream Comics
  • Space Action
  • Super-Mystery Comics
  • Sure Fire Comics
  • Ten-Story Love
  • Trapped!
  • Vicky
  • War Heroes
  • Web of Mystery
  • Western Adventures Comics
  • Western Love Trails
  • World War III

Action Labs Comics

Ait / Planet Lar

Ajax-Farrell Publications (1951-1958)note 

  • All True Romance
  • Apache Trail
  • Battle Report
  • Billy Bunny
  • Black C Obra
  • Brenda Starr
  • Bride's Diary
  • Bride's Secrets
  • Bruce Gentry
  • Bughouse
  • Captain Flight Comics
  • Captain Jet
  • Daffy Tunes Comics
  • Dark Shadows
  • Dear Heart
  • Eva the Imp
  • Fantastic
  • Fantastic Fears
  • The Fighting Man
  • The Flame
  • Frisky Animals on Parade
  • Frontier Trail
  • Full of Fun
  • Funny Fables
  • G-I in Battle
  • Great Exploits
  • Gunsmoke Trail
  • Happy Jack
  • Haunted Thrills
  • High Adventure
  • Hi-Ho Comics
  • Kiddie Kapers
  • Linda
  • Lone Eagle
  • Lone Rider
  • Lonely Heart
  • Madhouse
  • Men In Action
  • Midnight
  • Mighty Bear
  • Mighty Ghost
  • My Personal Problem (1955-1957)
  • Oklahoma Kid
  • Phantom Lady
  • The Rider
  • Rocketman
  • Samson
  • Secret Love
  • Spunky the Smiling Spook
  • Strange
  • Strange Fantasy
  • Strange Journey
  • Super Cat
  • Super Spook
  • Sweetie Pie
  • Swift Arrow
  • Swift Arrow's Gunfighters
  • Terrific Comics/Wonder Boy
  • Today's Brides
  • True Life Romances
  • Vooda
  • Voodoo
  • War Report
  • War Stories
  • Wild Western Roundup

American Comics Group/ ACG (1943-1967)

  • Adventures into the Unknown
  • Blazing West
  • The Clutching Hand
  • Commander Battle and the Atomic Sub
  • Dizzy Dames
  • Forbidden Worlds
  • Funnybone
  • Funny Films
  • Giggle Comics
  • Ha Ha Comics
  • Hi-Jinx
  • The Hooded Horseman
  • The Kilroys
  • Lovelorn / Confessions of the Lovelorn
  • Milt Gross Funnies
  • Moon Mullins
  • Operation Peril
  • Out of the Night
  • Romantic Adventures
  • Search For Love
  • Skeleton Hand
  • Soldiers of Fortune
  • Spencer Spook
  • Spy and Counterspy
  • Spy-Hunters
  • Teepee Tim
  • Young Heroes

Antarctic Press

Ape Entertainment

Arcana Studio

Archaia

Archie Comics

Aspen MLT

Avatar Press

Black Bull

Bongo Comics

Boom! Studios/KaBOOM! Comics

Broadsword Comics

Broadway Books

Caliber

Charlton

Comico

Comics Interview

Comix Tribe

Continuity Comics

CrossGen

Dell Comics

Dark Circle (an imprint of Archie Comics formerly known as Red Circle)

Department Of the Army

Desperado Publishing

Devil's Due

Different Mousetrap Press

Disney

Dork Storm Press

Dragon

Dreamwave Productions

Dynamite

EC Comics

  • Animal Fables (1946–1947) #1-7
  • Animated Comics (1947) #1
  • Blackstone the Magician Detective Fights Crime (1947) #1
  • Crime Patrol (1948–1950) #7-16 (continued as The Crypt of Terror)
  • Dandy Comics (1947–1948) #1-7
  • Fat and Slat (1947–1948) #1-4 (continued as Gunfighter)
  • Gunfighter (1948–1950) #5-14 (continued as The Haunt of Fear)
  • Happy Houlihans (1947) #1-2 (continued as Saddle Justice)
  • International Comics (1947) #1-5 (continued as International Crime Patrol)
  • International Crime Patrol (1948) #6 (continued as Crime Patrol)
  • Land of the Lost (1946–1948) #1-9
  • Modern Love (1949–1950) #1-8
  • A Moon, a Girl...Romance (1949–1950) #9-12 (continued as Weird Fantasy)
  • Moon Girl (1947–1949) #2-6 (continued as Moon Girl Fights Crime!)
  • Moon Girl and the Prince (1947) #1 (continued as Moon Girl)
  • Moon Girl Fights Crime! (1949) #7-8 (continued as A Moon, a Girl...Romance)
  • Picture Stories from the Bible (1944–1946) #1-3 (New Testament edition, Old Testament edition published by DC Comics)
  • Picture Stories from American History (1945–1947) #1-4
  • Picture Stories from Science (1947) #1-2
  • Picture Stories from World History (1947) #1-2
  • Saddle Justice (1948–1949) #3-8 (continued as Saddle Romances)
  • Saddle Romances (1949–1950) #9-11 (continued as Weird Science)
  • Tiny Tot Comics (1946–1947) #1-10
  • War Against Crime! (1948–1950) #1-11 (continued as The Vault of Horror)
  • The Crypt of Terror/Tales from the Crypt (April/May 1950 to February/March 1955, 27 issues)
  • The Vault of Horror (April/May 1950 to December/January 1955, 29 issues)
  • The Haunt of Fear (May/June 1950 to November/December 1954, 28 issues)
  • Weird Fantasy (May/June 1950 to November/December 1953, 22 issues)
  • Weird Science (May/June 1950 to November/December 1953, 22 issues)
  • Crime Suspen Stories (October/November 1950 to February/March 1955, 27 issues)
  • Two-Fisted Tales (November/December 1950 to February 1955, 24 issues)
  • Frontline Combat (July/August, 1951 to January 1954, 15 issues)
  • Shock Suspen Stories (February/March 1952 to December/January 1955, 18 issues)
  • MAD (October–November 1952, ongoing to this day)
  • Three Dimensional E.C. Classics/Three Dimensional Tales from the Crypt of Terror (Spring 1954 to March 1954, 2 issues)
  • Panic (February–March 1954 to December/January 1956, 12 issues)
  • Weird Science-Fantasy (March 1954 to May/June 1955, 7 issues)
  • Piracy (October/November 1954 to October/November 1955, 7 issues)
  • Impact (March/April 1955)
  • Valor (March/April 1955)
  • Extra! (March/April 1955)
  • Aces High (March/April 1955)
  • Psychoanalysis (March/April, 1955)
  • M.D. (April/May 1955)
  • Incredible Science Fiction (July/August 1955)
  • Confessions Illustrated (1955-1956)
  • Crime Illustrated (1955-1956)
  • Shock Illustrated (1955-1956)
  • Terror Illustrated (1955-1956

Eastern Color Printing Company (1933-1955)

  • Famous Funnies: The series that is generally considered to be the first true comic book. It mainly published reprints of newspaper comics, but it eventually added original material. It also had a oneshot precusor called "Famous Funnies - A Carnival Of Comics".
  • Big Chief Wahoo
  • Buck Rogers
  • Buster Crabbe
  • Century of Comics
  • Club "16"
  • Dickie Dare
  • Mickey Finn
  • Movie Love
  • Personal Love
  • Daisy Comics
  • Heroic Comics
  • Jingle Jangle Comics
  • Juke Box Comics
  • New Heroic Comics
  • Reg'lar Fellers Heroic Comics
  • Steve Roper
  • Sugar Bowl Comics
  • Tales From The Great Book

Eclipse Comics

Eros Comix

Event Comics

Evil Twin Comics

Fantagraphics

Fiction House

First Comics

First Second

Fishwrap

Gold Key

Graphic Universe

Hannagram

Harper Teen

Harvey Comics

Heroic Publications

Horndog Studios

Innovation

Kenzer

King Features

LEGO

Malibu

Mariner Books

Minx

Mirage Publishing

National Hockey League

NEC

Nedor Comics

Nuage Editions

Octopus

Oni Press

Pantheon Books

Paradox Press

Paws

Platinum Studios

Radical Comics

Random House

Red 5

Revolutionary Comics

Rip-Off Press

Roaring Book Press

Sega

Scholastic

Shanda Fantasy Arts

Simon & Schuster

Slave Labor Graphics

Studio Foglio

Tekno Comix

Titan Publishing Group

Top Shelf

Topps

Tower Comics

Tundra Comics

UDON

United Feature Syndicate

Villard

Viper Comics

Wildstorm Productions

Zenescope

Zondervan Graphic Novels

Independently published