Done in a more sensible fashion in Magical Girl Lyrical Nanoha. It's more along the lines of "Have you tried not being a group of morally-devoid combat cyborgs?" At the end of her fight with Nove, Wendi and Deed, Teana tells Nove that if she cooperates, she will be able to start over and enter rehabilitation, prompting Nove to respond that they, being combat cyborgs, are made to do battle. Teana responds that Subaru is a case of someone who was made as a combat cyborg but nevertheless became a kind person. Teana's three opponents get the message and enter rehabilitation, with Wendi and Nove crediting Teana as the one who inspired them to change.
X-Men, to the point of extreme Lampshade Hanging, where people (like Spider-Man) in some issues get gays and mutants confused. Mutants who can pass for human are sometimes referred to being "in the closet". The biggest group of people rallying against mutants are conservative Christians, who think their existence is a sin against God. There have been numerous attempts to "cure" mutants, as well as to kill them off as "abominations". Basically, after the racial civil rights of the 60s and 70s cooled down, the franchise was adapted to mirror the gay rights struggle, which it actually fits better in many respects (since mutants can be born to anyone, don't become different until puberty and you cansometimes tell their condition by looking at them, but notalways.).
This is taken to its logical extreme in Dark Avengers-X-Men: The Beginning, where it's revealed that the San Francisco neighborhood known as the Castro is a mutant neighborhood instead of a gay community like in real life. Vote no on Prop X and all that. Goddammit, Marvel, there are actual gay people in your universe. This is especially baffling when you consider that M-Day and other events eliminated all possible similarities between gay people and mutants. There are, at a maximum, 500 mutants alive worldwide. Theirs is the last generation; no more are being born. So, among other things, the idea of mutants as an even somewhat visible minority anymore is insanely ridiculous.
And then changed again in Generation Hope. With Hope's return and survival? Mutants begin being born again, thus becoming a minority again.
A special issue that dealt with a teenage boy being "outed" as a mutant. After training to control his powers, he went home to find that his parents, originally rejecting him, have finally accepted him; that the girl he had a secret crush on is now interested in him; and that his oldest friend since they were babies has shut him out completely. Hmmm...
Many real-life minority-rights groups are beginning to find the association a bit condescending, considering comics' ongoing problem with diversity, seeing it as the co-opting of a struggle for characters that are overwhemingly straight and white.
Runaways played with the trope with Karolina, who felt different all her life without ever knowing why, and there eventually comes the major revelation that she is an alien. However, it turned out she was an alienandgay, and she asked herself this question. When the team had unknowingly let a vampire into their hideout, before Karolina came out to her friends, she mentions to the newcomer how she hates always feeling different and abnormal, and she decides that she wants to feel like a normal teenage girl (And since she is sixteen, and he is cute, and they are alone...). Of course, it is never that simple, and in a very Real Life way (except for the vampire and alien bits) she falls into a suicidal depression when she can not fit in like she wants to, but she also learns to accept herself, and is accepted by her friends, and eventually becomes proud and unapologetic of her heritage and sexuality.
This is later used when Karolina begins to date Xavin, who willingly spends time as a girl with her after finding out she is a lesbian. Some Majesdonians (Karolina's alien species) later track her down and, upon hearing that she and Xavin are in a relationship, say that it is "disgusting"...because a Majesdonian is dating a Skrull.
In Luminosity, vampires do simply change upon turning in a few key ways. Most of them are hard to understand, and after a few questions from her father about stuff that's perfectly normal for a vampire, Bella thinks:
I half expected him to ask if I'd ever tried to stop being a vampire.
The Blue Rajah, a cutlery throwing superhero from Mystery Men, is mortified to be caught by his mother rummaging through her cutlery drawers, and desperately tries to brazen it out by daring her to disapprove of his superhero lifestyle. She turns out to be far more supportive and loving than he expected.
One of the jocks in Cursed assumed that this was what the newly-infected werewolf was concealing. As the jock in question had been hiding his own sexual orientation, confusion ensues.
Trope Namer. In X2: X-Men United, Bobby Drake's parents find out that he's a mutant and have pretty much exactly this reaction. Complete with his mother asking him “if he’s tried...notbeing a mutant?”. The filmmakers consulted Ian McKellen for the scene due to his experience being gay during much less forgiving times. Many viewers consider it narm, but this is likely the point, as many a homosexual who have endured the 'real' version of the line have likely wondered how close family could seriously ask such an ignorant question.
This pops up a second time. When Nightcrawler asks Mystique why she doesn't use her shapeshifting powers to blend in with normal humans, she replies, "Because we shouldn't have to."
The LGBT metaphor is admittedly less subtle. Charles and Erik look like average humans and have passing privilege, but have still strongly affected their lives. Raven, on the other hand, can pass for "normal" at the cost of it being very exhausting and undermines her self-confidence, making her somewhat of a metaphor for a transgender person. Raven's comparison is even blatantly explained through a conversation with Erik — she doesn't have to perfectly "pass" as a non-mutant woman to be beautiful and have worth.
This crops up in Muppets from Space when Gonzo discovers he's an alien; "But I didn't choose to be one. I mean, I've always had alien tendencies, and this just makes sense to me."
Jack feels this way about Greg being a nurse in Meet the Parents. Even as he's extending an olive branch to Greg and trying to be less intimidating and close-minded, he basically paraphrases the page quote.
Rowling has said that werewolves and Lupin in particular were actually a metaphor for segregation in general, but also for society's negative reactions to the disabled. Lupin's lycanthropy forces him to need many special accommodations just to live day to day, such as a potion he has to take for the rest of his life, or the more elaborate quarantine Hogwarts had to set up for him as a child.
The movie version of Azkaban is particularly anvilicious about this. In the book, Lupin has no problem talking about being a werewolf at the end-of-the-book wrapup with Harry, whereas in the movie he hesitates and uses lots of euphemisms that make it sound like he's talking about something else entirely...
Lupin: This time tomorrow, the owls will start arriving, and parents will not want a wer... er, someone like me teaching their children.
Lupin: Besides, people like me are... Well, let's just say that I'm used to it by now.
He lampshades his heavy use of euphemisms somewhere along the line, saying, "James used to call it my 'furry little problem'. Many of my classmates were under the impression that I owned a very badly behaved rabbit."
This was likely done on purpose, as David Thewlis, the man who played Lupin, was convinced his character was gay and professed to be disappointed when he married Tonks. A sizeable chunk of the fandom concurs.
The world of the Mercy Thompson series plays around with this trope. There's a lot of religious opposition, especially toward the fae, but it's quickly demonstrated to be a lot more reasonable than it seems at first glance. Sticking those fae forced out of the closet onto literal reservations, however, certainly fits a version of this trope. On the other hand, there are gay werewolves, who are discriminated against both as they would be in the real world, and by werewolves that have their own discriminatory beliefs on the matter.
Homophobia among werewolves is partially explained by the near immortality of the species. Many or most are centuries old, born when homosexuality was unacceptable, and as they grow older they find it harder to change with the times. The Columbia Basin pack, which does have a gay member, is explicitly stated to have accepted him in large part because many of the other members were only a few decades old. In addition, werewolves can smell arousal, so having a gay man among many others who are good-looking, straight and short-tempered makes violence near unavoidable. An Alpha may deny a gay werewolf membership not based on his personal homophobia, but because he isn't strong enough to prevent the fights caused by inadvertent flirting.
In the fantasy novel Weavers of Saramyr, people born with magical powers are called "Aberrant." Veteran Aberrant Asara gives protagonist Kaiku what can only be described as a "coming out of the closet speech", urging her to accept her powers and be proud of them... moments before a big Les YayShip Tease moment.
The Dresden Files invokes this trope, as wizards are supposed to maintain secrecy at all times and not reveal to the rest of the world that they exist, lest non-wizards become terrified and kill them. Averted in the case of the series protagonist, who not only puts "HARRY DRESDEN, WIZARD" on his office door and is listed in the Yellow Pages under "Wizards," but also goes on his universe's equivalent of Jerry Springer to talk about magic and promote his business. Twice.
Amusingly, Harry's association with White Courtvampireand his half-brother Thomas Raith has led people to assume he is gay. They tend to have a Not That There's Anything Wrong with That attitude to it, and when they're prejudiced, Harry has used that to his advantage. And Murphy won't shut up about it, so he's probably never going to live it down.
A mild version of this is in The House of Night series. In the first book, when Zoey gets the Mark of a vampyre, all she knows is that vampyres often disappear. She then discovers that there is a school for them (the titular "House of Night") and that many celebrities are vampyres. Being a vampyre is treated similar to being gay in this universe. Because of this, her strict Christian stepfather disowns her. Vampyres also have to cover up their Mark in public to avoid being harassed.
In Robert Jordan's Wheel of Time, male channelers are treated like this... at the very best. Justified, though, as they are doomed to go insane, which will have disastrous effects to anything and anyone in vicinity, and at the end die a horrible death.
Bella pulls this pretty much straight (in wording, at least) on Jacob when confronting him after figuring out that he's a werewolf.
Bella:Could you...well, try to not be a...werewolf?
In the film Jacob responds: "This isn't a lifestyle choice, I was born like this."
One of the most Anvilicious examples is Raxtus, the "fairy dragon" from the Fablehaven series. These quotes make it pretty obvious:
"I was incubated and hatched by fairy magic, and I came out...unique."
"I'm the pretty dragon. The funny dragon. Problem is, dragons are supposed to be fearsome and awe-inspiring. Not witty. Being the funny dragon is like being the bald mammoth. Being the pretty dragon is like being the ugly fairy."
"My father is...the king of dragons....And I'm his greatest disappointment. Raxtus the fairy dragon."
"Guess what my breath weapon does? Helps things grow! And the only magic I can do is defensive stuff like hiding, or else healing. Again, like a fairy."
"I can't manage to look like a person....I look like a boy fairy with butterfly wings."
In Hero by Perry Moore, Thom is an extreme example of this. He has healing powers, but his father, a former (non-superpowered) superhero who left in disgrace, now hates anyone with powers. Then there's the fact that Thom's also gay...
In Bill Brittain's book, Wings, the main character grows a pair of batlike—and ultimately functional—wings. He is forced to have them surgically removed in the end, however, at the insistence of his father.
Dwarfs in Discworld are suddenly going through a period of this. The series parodies Our Dwarves Are All the Same by having the genders be identical. Females have beards, dress the same as males, and dwarfish courtship consists largely of trying to tactfully find out what the other dwarf's gender is. But ever since Feet of Clay, a few dwarfs (mainly the younger ones) have started wearing dresses and makeup, and admitting they don't actually like beer all that much (they keep the beards, though). Older, more conservative dwarfs are horrified to find that some of their sons may actually be daughters.
It's also entirely possible that some of the dwarfs doing this are biologically male (their culture doesn't even really recognize the concept of gender; dwarfs are dwarfs), making this seem even more like a metaphor for gender identity; it's not about what they were born as, but what they want to live as.
According to Robert M. Price, H. P. Lovecraft's "The Outsider" has compelling parallels to a coming-out story. Though the implications are probably unintentional, this story may be one of the oldest examples of this trope.
Vampires in True Blood are very analogous to gays. They "come out of the coffin" to demand civil rights and are mostly opposed by members of fanatical religious sects who spout catchphrases such as "God Hates Fangs". Also, the show sometimes casts the vampires like racial minorities, made more overt due to its setting in the American South. During one scene, a bigoted policeman repeatedly calls Bill "boy" while treating him unfairly. However, due to the high number of murderous vampires in the show, there's a fair bit of Broken Aesop and Strawman Has a Point going on. Actually, for all that he is "nice" now, this used to include Bill just as much.
While many viewers find that it fits the trope, the creators have outright denied that vampires are allegory for homosexuals and Alan Ball calls this interpretation "lazy." If anything, the show, and the books, are preaching the _opposite_ moral, targeting the "everyone should all just get along" and "society is victimizing me for being _special_" memes from the '90s and ripping them down mercilessly. After all, even in the case of "good" vampires, the people that treat their condition as a NTTAWWT thing are dead wrong, often literally.
Some have criticized the implied metaphor, pointing out that gays generally have neither the urge to rip people's throats open nor superpowers to allow them to do so with impunity.
Although that doesn't stop it from being used to awesome effect.
Protester: Hey Fang-Banger!
Hoyt: You better not be talking to me.
Protester: What if I was?
Hoyt: See that woman right there? Not that Devil, but that Woman, yeah, she got fangs. And yeah, you can bet your ass that we are doing it all the time because we are in love! And there is not one damn thing wrong with being in love! Now, how can you do this, and still call yourself a Christian?
Protester: I am a Christian, god damn it!
Hoyt: I am clearly more of an Christian than you. Because I got love in my heart. And you got nothing but hate.
Buffy the Vampire Slayer pulls this a few times. First and foremost, Joyce's reaction to learning about Buffy and vampires was, literally, "Have you tried...not being the Slayer?" She later describes herself as "marching in the Slayer Pride parade." To be fair, Joyce's reaction is a lot more understandable than most examples on this page, since her biggest concern is that Buffy could get seriously hurt or killed being the Slayer.
In "Phases," Larry is suspected of being a werewolf, and Xander has a talk with him about having urges and desires he can't control...but it turns out Larry's not a werewolf, he's just gay.
Angel then reverses that: Cordelia misreads the signals she's been getting from the new vampire Harmony, and ends up thinking Harmony's a lesbian. She calls Willow to ask "why didn't you tell me?" and the conversation is full of mixed signals. Finally:
Not to mention Willow and Tara's "witchcraft = lesbian awakening" subplot. Lanterns were still being hung on that one in the final season.
Anya: (about to do a spell with Willow) This isn't gonna get all sexy, is it?
The Vampire Diaries hilariously discusses and plays with this trope upside down and sideways. Caroline, a young vampire, is seriously discriminated against and tortured by her father who is trying to cure her of her vampirism through punishment. Her mother's explanation for her father's behavior? Her parents were "raised a certain way to believe certain things" about vampires that aren't necessarily true. He even chooses to die instead of becoming a vampire because his beliefs are all he has. Irony of ironies? Her father is gay and left his wife because he could no longer live a lie. Needless to say, extremely Genre Savvy vampire Damon points out the incredible...quirkiness of the situation.
The live-action series The Tick had an episode of this trope, centered around Arthur coming out as a superhero to his mom and sister. Tick is referred to as Arthur's "Partner" and "Special friend". In one scene the mom and sister, upon first entering the restaurant Arthur and Tick frequent, notice a superhero leaving and ask, "Is this one of those kind of places?"
Creator Ben Edlund later regretted putting this in people's minds when they made the episode about the relationship between superhero and sidekick, which he described as "very marriage-like" in the commentary.
Deep Space Nine also invoked it with respect to Dr. Bashir's genetic enhancement. Bashir was outed as having a trait that is not only considered revolting and wrong by the general public but is also illegal and can lose his military job and even his citizenship, even though Bashir wasn't the one who chose the trait in the first place. That episode read as if it were a metaphor for forced outing of gays. To make matters worse, it creates an Unfortunate Implication with respect to future references to other genetically enhanced characters.
Dinosaurs has an episode where Robby suspects that he mights be (GASP) an herbivore! Herbivores are treated the same way in dinosaurs society as gays are, complete with "herbivore bars" and being called "Vego" as a slur.
Fridge Logic makes this weird once you realize that several of the dinosaurs characters are based on (B.P. Richfield's Triceratops comes to mind, although he did try to eat Robby once) are herbivores.
Dexter use this trope. And in that case, when they say 'monster', they mean killer.
In Merlin, Camelot's oppression of magic users can be read as allegory for homophobia. Part of the prejudice against sorcery is based on the belief that it's a learned skill, mirroring the real life debate over whether homosexuality is innate or a "lifestyle choice". In the series four finale, Merlin even tells Agravaine that he "was born with it" (meaning magic). And there's the constant Arthur/Merlin Ship Tease...
Completely inverted in Swedish comedy show Hjälp (Help), whenever resident sissy Benjamin tries to explain to his family that he's just an average guy. When came out to them and told them he was straight, his sister called him revolting, his mother started crying and his father disowned him. Causing Benjamin to meekly tell them that he was only kidding, of course he's really gay.
Taken to ridiculous extremes in the third season;
When he accidentally become a bank robber, his father gave him his old Luger that he used to rob the post office with and offered him to come along to Denmark for a hit ("some pesky witness that needs shutting up"). Then there's the family tied up in the bathroom...
When he ends up being recruited by some Nazis, his parents start recollecting how they first met at a Nazi rally and how proud they are of him following in their footsteps.
When he's forced to convert to Islam (as part of a knife-point marriage), his parents proudly reveal that they are actually part of an Al Qaeda terrorist cell and asks him for help in bombing the local Danish hotdog stand.
In Glee, the character of Bryan Ryan crusades against show choir, because he's resentful that his time in New Directions didn't turn into lifelong stardom. It turns out that he's "living a lie," and tells his wife he goes on business trips but instead goes off to New York to see Broadway plays, and has a stack of playbills in his basement which are "like porn." Possibly a parody of the trope, since Glee features openly homosexual characters and has dealt directly with gay issues in other plotlines.
Heroes originally had this as a major plot point. Claire's friend Zach was going to embrace his homosexuality, mirroring Claire's embrace of her new powers. Although Executive Meddling nixed the gay reveal, which is perhaps why Claire ends up wangst ridden for the rest of the series.
Dryer Jigen tries to be a terrifying menace, but can't resist helping people in need. By the end of the episode he gives up evil and becomes a hairdresser. Really.
Gomi Jigen was the same. He never wanted to do no harm to anyone in the first place, because the main part of his mind comes from a teddy bear which Ako used to care a lot for when she was a child. Anyway, he came back to his senses thanks to Ako, only to have a disgusted Maria kill him, inadvertently hitting a Berserk Button in Blue Swallow in the process.
The Police's Roxanne. Essentially telling a prostitute to not be a prostitute.
After Elton, a gay entertainment site, addresses this trope:
Especially the Changelings of Changeling The Dreaming, since the other supernatural creatures are born or turned from sires or parents, but Changelings may be born to any family, love theater, sex, and the artsnote PS: the Nockers say "fuck that.", and have a miserable time fitting in with "banal" normal society. Changelings also either come into their fae identities in early childhood (realizing they're "different" from the other neighborhood kids) or during puberty (dealing with this new rush of sensations and body issues).
Although in that case, lycanthropy seems to be more related to puberty itself, especially considering the whole monthly-cycle connection (for further exploration of this theme, see Ginger Snaps).
There's also the minor detail (at least in Apocalypse) that the rate of Garou births in their established families, one in ten, is the same as the oft-cited estimate of the percentage of gay people in the general population.
Traveller (the old SF RPG) balanced psionic characters by making psionics illegal in the Imperium.
And there's Paranoia, of course, where everyone (EVERYONE!) has an unregistered mutant power but having an unregistered mutant power means a death sentence from the Computer...you COULD register your power but that puts you under suspicion. Get your clone warmed up.
Not to mention everyone also belonging to highly treasonous secret societies.
And it being entirely possible to be a secret member of the anti-mutant league while being a secret mutant...
Something that at least one edition of the game compared to "passing for white as a member of the Ku Klux Klan."
There's a comedic short play called Jimmy the Antichrist about a boy coming out to his parents as, well, the Antichrist (though he's not as evil as that title would suggest). It's all very Does This Remind You of Anything?, complete with the parents saying "Have you tried not being the Antichrist?" This is lampshaded several times by Jimmy's sister, who keeps asking him whether he's sure he didn't mean to say he was gay.
In Blaze Union, Baretreenu was so adamant that her young son Gulcasa never realize that he was a demon that she placed a powerful, permanently damaging seal on his powers and concealed his true identity even from himself. Over a decade later, when he realizes he has demon blood anyway, a very big deal is made out of his choosing to live as the person he was born as. Gulcasa points out that demon blood in and of itself isn't a bad thing, and what's important is whether he personally makes good or bad choices with his life; his mentor Medoute retorts that his demonhood is absolutely an inherently evil thing, and that she can't forgive his decision to be true to himself. This, among other things, makes the scenario read very much like a Coming-Out Story.
Mass Effect touches on this with biotics - people who gain Gravity Master powers from exposure to Element Zero while in utero. To make the most of their abilities, they need special implants attached during puberty (unless they're asari). As humans are still new to the galactic community, many human biotics face discrimination due to fear, religious reasons or false ideas of their abilities. This also applies to the turians, who've been around a lot longer - their military mistrusts biotics due to their use as spies or assassins during the Unification War. Turian biotics are grouped together in 'cabals', with mixed results.
In the Dragon Age series mages are basically magical mutants born to elves and humans with a stronger connection to the Fade than others. Untrained mages are vulnerable to Demonic Possession and are taken to Circles to be trained and watched by Templars who also double as Mage Killers if they do become possessed or "apostates" that try to run away from their Circles. Besides the legitimate danger of having a magic-user around to unsettle parents there is also the undercurrent of "magic equals sin" courtesy of the creation of the Darkspawn and other magical transgressions of The Magocracy that once ruled Thedas; many parents are happy to be rid of their "tainted" children despite the fact that magic ability is universally acknowledged as hereditary and not due to the mage's actions. Of course, there are also examples of parents and families that subvert this: Isolde in Origins makes some really bad choices to keep her mage son from being taken away, Finn in the Witch Hunt expansion pack is loved by his parents enough for them to give him an Overly Long Name and a crappy yet lovingly made hat (that actually has good stats) while the Hawke family in Dragon Age II chose to stick together and risk persecution by the Templars despite having at least two apostate mages among them.
Surprisingly, homosexuality itself isn't that big a deal in the setting (or at least not enough for the authorities to bother making laws against it), so the traditional homosexual comparison isn't valid. There is a way to not be a mage through being magically cut off from the Fade by being made "Tranquil" and losing all magical talent andemotion; this is considered either a merciful fate opposed to execution or a Fate Worse than Death.
That doesn't cut down on the analogies, however, such as a romanced Anders in the second game speaking hopefully of those like him (a mage) and Hawke (either a mage like him or a warrior or thief) being able to openly be as they are together some day. Those who are opposed to mages being made "Tranquil" treat it more or less analogous to any kind of "cleansing"/witch hunts (i.e. torture and/or genocide or some kind of unethical treatment) done in real life. There's also questioning of this kind toward Qunari following (or 'failing' to follow) the Qun as well (but with racial and cultural/religious overtones), and the way the mercenary responds to Saemus after killing Ashaad seems to carry both the Fantastic Racism and disgust toward the kind of she might have thought they were having. The reactions of the public to homosexual relationships in Dragon Age aren't entirely explicated on, either, since most of the ones seen are private, or with characters who don't care what anyone thinks of them, though the initial reactions of any other same-sex characters being flirted with seem to imply that homosexuality isn't something openly talked about, at least.
Regardless, the mages are treated horribly for something they can't control, with extremely unreasonable standards. Every mage is thought of as a possible blood mage or someone that could be possessed at any moment. If they leave their Circle for any reason at all they're denounced as apostates, regardless of whether they intended to return or not. Kirkwall is particularly bad about this, as many of the templars that you see are cruel and iron-fisted, continually persecuting the mages and not treating them with any kind of decency.
Though it is worth noting that there is a very real reason why mages are locked up from birth. If a mage cannot learn to control their powers, they can cause great destruction to both themselves and those around them. Magic by itself is very powerful and destructive. But beyond that, mages who cannot control their powers can be possessed by all sorts of demons from the fade, who many times will turn and try to turn other mages into demons. If left unchecked, it can quickly become an epidemic, as you see in the Mage's Tower in Dragon Age: Origins. An untrained mage is a danger to everyone. The religious aspect of the circle, whether true or fake, is just icing on the cake. This does not excuse some of the terrible abuses some Templars have done with their position however.
Also "have you tried not being a Nazi" (about Ervin)
Also played with in a now-defunct super hero webcomic called Queer Nation, where everyone gay got superpowers from radioactive dust given off by a pink comet and was written as X-Men with the subtext changed into text. Oh, and bisexuals got superpowers too, but they only worked half of the time. Asexuals and pansexuals weren't addressed. Transsexuals had powers that were mostly useless until something amazing would happen that would kick them into god-tier. One of the main characters was a male to female transsexual who called herself Miss Thang and started with the ability to manipulate clothes (first just moving them, then morphing them), but it was implied that it would one day extend to complete metamorphic control over all matter.
Used in Darken. A werebear character can suppress the bear inside him by an act of will. But apparently trying to concentrate on not being a bear is hard.
Played for laughs near the beginning of Keychain of Creation, where Marina claims N-Word Privileges for 'anathema', the term Immaculate Dragon-Blooded use to denounce Solars and Lunars like her as soul-stealing demons.
In the South Park episode "Big Gay Al's Big Gay Boat Ride" Stan finds out his dog Sparky is gay and tries to command him to not be gay the same way you would command a dog to do tricks.
Stan: Don't be gay, Spark. Don't be gay.
In the "Bats!" episode of My Little Pony: Friendship Is Magic, Fluttershy is turned into a feral vampire bat-pony due to a magical mishap. When her friends discover her this way hanging from a branch, Rarity asserts "Fluttershy, sweetness. Please come down. And do stop being a vampire bat."
Often happens to people with mental, developmental or social disorders when they are trying to come out. This can in extreme cases result in severe harm and trauma, if the 'not being X' part is forced upon them.