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"I don't know what happened to Antonio Bay tonight. Something came out of the fog and tried to destroy us. In one moment, it vanished. But if this has been anything but a nightmare, and if we don't wake up to find ourselves safe in our beds, it could come again. To the ships at sea who can hear my voice, look across the water, into the darkness. Look for the fog."
This isn't the normal mist that comes at a bad time, obscuring vision or providing dramatic tension. It's certainly not that serene mist that comes just after a gentle rain... no, this fog is malevolent and evil and out to get you.
Everyone knows that an Ominous Fog is a bad sign in movies, books, and television shows. One of the most sure-fire ways of generating that edgy feeling of paranoia is to enshroud the setting in a dense, opaque mist. Because anything could be hiding in there...
An Ominous Fog turns into a Fog of Doom when it is trying to bite you. Sometimes the fog itself is the threat. No mere mist, the Fog of Doom is often poisonous, or acidic, or causes men to go mad. Other times, the Fog of Doom conceals other threats that come out of the mist to take and devour you so quickly that your friends don't even know you're gone until they look around and see you're just not there.
Either way, you better avoid walking into a mist at all costs.
This trope also can include other sight obscuring conditions such as dust storms (seen in the Mummy), supernatural darkness, or smoke; fog is simply the most common mechanism to achieve the effect.
For things who can turn themselves into smoke, see Super Smoke. For ordinary poisons, see Deadly Gas.
For better clarification the mist is a stand called Justice controlled by the old lady at the bottom, Enya Gail. Justice can control the body, living or dead, through wounds created by Enya.
The ninjas of Kirigakure (meaning "Hidden Mist") in Naruto use fog for their silent killing techniques. So, it's not the fog trying to kill you, but ninjas in control of the fog trying to kill you.
The Godaime Mizukage takes this a step further. Like the village she leads, she can use mist-like techniques. The difference is, hers can fill a room and literally melt people.
Somewhat, in one of the Pokémon manga there was a Haunter called the "Black Fog". Yeah, he wasn't friendly.
In Sailor Moon, Sailor Mercury can produce this with her Mercury Aqua Mist attack (Sabăo Spray in The Ninetiesanime) producing a concealing fog that gives comrades an opening to attack an enemy unawares. (The fog itself had no special properties; she was The Smart Guy rather than having much in the way of offensive power. She gets more direct means of attack as once or twice per season the gang gets more powers.)
An industrial acccident in Cloudsdale produces the titular fog in Flash Fog. It's a miles-wide sphere of cloud that simply can't be manipulated and will eventually set "solid". Plus, the interior of it is cold enough that prolonged exposure can freeze Earth Ponies to death. Since it's spread itself over a large area of farming country, it's become very disruptive and has to be gotten rid of as quickly as possible.
Creepy fog-cloaked areas called "thinnies" are a rare, but deadly and unpredictable hazard in King's The Dark Tower series.
In Larry Niven's For A Foggy Night, the mist isn't actually mist, but is rather times when the various alternate timelines intermesh. When you walk out into a fog, you're actually walking into an alternate world... its just that most of the time the "alternate" is so close to your original world you never notice. But sometimes, just sometimes, you cross over into a world that's completely different...
Michael Moorcock's Elric of Melniboné has the Groaning Mist, which after enveloping its victims attempts to drive them insane with hallucinatory voices whispering of their fears and inadequacies.
The Wheel of Time has a city full of murderous mist. Touching the corrupted fog of Shadar Logoth will either kill you outright or infect you with an eventually-lethal Hate Plague. Originally, the fog was contained in the city, but once one of the infected escaped into the countryside, it came with him, and is now (under the command of the aforesaid infectee) capable of forming spontaneously in unexpected places and ripping apart everyone within.
In William King's Warhammer 40,000Space Wolf novel Grey Hunters, the Chaos forces cause a green and yellow fog to boil up. It obscures vision, allows their enemies to sneak up, and contains some kind of poison.
The Fog from James Herbert back in 1975, not related to the John Carpenter film of the same name. In this novel, a fog descends over Britain that turns almost the entire population insane.
M.P. Shiel's 1901 novel The Purple Cloud has nearly the entire human and animal population of Earth being killed off by the mysterious title cloud.
The Tales From Camp Crystal Lake series of books by Eric Morse note Mother's Day, Jason's Curse, The Carnival and Road Trip all feature a yellow fog which seems to make everyone feel more negatively, lubricating the lethal intentions of whomever finds the hockey mask as well as the Final Girl.
Features in The Hunger Games. The fog in question is a kind of nerve gas that burns the skin and causes seizures and muscle failure.
In Septimus Heap, the bank of Fog surrounding the House of Foryx conceals an Abyss.
Tales of the Magic Land (a series of loose Russian translations of the Wizard of Oz books) has a book aptly named The Yellow Fog where a witch named Arachna who attempts to subdue the Magic Land with the titular fog. While not lethal (it's meant to subdue rather than exterminate, after all), it has several negative effects: it's toxic, for one, and it also blocks off the sun leading to intense cold in the usually winterless Magic Land.
In Mistborn, the mysterious threat called the Deepness is actually the normally benign mists, which Ruin intensified until they form a crop-killing particulate winter.
An early example can be found in The War of the Worlds. The Martians use a weapon called Black Smoke that acts very much like a semi-sentient, malevolent killing black mist. It's described in the book as moving almost like a living thing to cut off escape and trap its victims.
The Smog in Un Lun Dun is effectively a sentient version of the smog that covered most of industrial-revolution London, and as such, is very lethal. It is also able to possess people to an extent, creating hideous creatures known as 'Smombies' and has been possessing Unstible for some time.
The mist-loving Sea Zombies in the Dungeons & DragonsGreyhawk Adventures supplement were a ripoff of inspired by John Carpenter's zombies.
Dungeons & Dragons also features air elementals, crimson deaths, vampiric mists, and mist dragons.
Ravenloft's most iconic set-piece is The Mists that hang over most of the Land, and this is often used as a means to pluck players out of their home world. It gets to a point where experienced players will run screaming from the slightest sign of mist. One of the nastiest salient powers mentioned in the Ravenloft supplement Van Richten's Guide To Vampires was the possibility of a Patriarch vampire using its energy-drain ability while in mist-form. This was a particularly terrifying prospect under 2nd Edition rules, when there was virtually no way to fight back against a gaseous-form opponent.
There was also a spell call Murderous Mist, which was a druid spell that created hot steam that could boil your eyes. Then again, there are the more classic Stinking Cloud, Cloudkill, and Acid Fog spells.
In the Villains And Vigilantes adventure Devil's Domain, killing demons released a cloud that caused humans to go insane and attack you.
London in Unhallowed Metropolis is cloaked in heavily toxic smog. Going outside without a gas mask or at least a damp cloth to cover your mouth and nose causes unconsciousness in short order, and death not too long after. Direct sunlight penetrating the smog layer is rare, and on the worst days, it blots out the sun entirely. There's nothing supernatural or actively malevolent about it, but that's a small comfort.
Legend of Legaia provides a misguided Big Bad who creates the Fog of Doom, which warps the titular Utopia into a Crapsack World. But otherwise, the fog was harmless. Unless you were wearing a Seru, as the fog turned those, and anyone who was wearing one, into a horrible monster. And given that, before the fog, everyone was using them non-stop to do everything, it was a fog of doom. Oh, and if you ran into one of those previously mentioned monsters that were lurking in the mist just outside of the few remaining safe havens, you were screwed, since ordinary weapons were worse than useless against them.
In City of Heroes, Dark Astoria is a zone covered in a frustratingly opaque mist, filled with arcane and supernatural enemies. For extra points, all of the neighborhoods and landmarks in Dark Astoria are named after old school horror authors, filmmakers, and characters. Adding to the creepy lethality of the zone, players can see vague images of the zone's long-dead inhabitants in the mist... who fade upon approaching.
Final Fantasy IX's Mist was the source of many a scary monster. On the other hand, it was also the source of many a black mage. The Mist was created by the Iifa Tree, which processed the souls of the dead into Mist. This then was to clear Gaia of life to make room for the denizens of Terra. It had the bonus effect of making people bloodthirsty, accelerating the whole process.
There was a fog in Blue Dragon that inebriates its inhalers. And it's at sea. Close to rocks to run into.
Some of the early pre-release materials for Silent Hill Origins suggested that the town's Ominous Fog would cross the line to become an active, amorphous enemy. The game switched production teams midway through development, and though a later sequel, Silent Hill: Homecoming, did feature an otherwise corporeal monster named "Smog", the Fog of Doom idea never panned out.
The fog that appears in the TV World in Persona 4. It causes fatigue for those not wearing special glasses that allow them to see in it. It crosses over to the real world every so often and when it recedes, corpses are found in high places. Near the finale of the game, the fog starts seeping into the real world, and it's revealed that those exposed to the fog for too long will eventually turn into Shadows — which is how Izanami, the Big Bad behind it all who you fight in the True Ending, wants things.
The Kvaldir, also known as the walkers of the fog, from World of Warcraft are ghostly sea raiders who only show up in areas of very heavy fog. There's also the noxious orange mist that passes for atmosphere in the zombie-infested Plaguelands. In high enough concentrations, it's a vector for the Scourge.
In Lost Kingdoms, the black mist contains monsters and is the influence of the Big Bad. A Side Quest reveals a scientist who tried to save his hometown, but ended up creating a white mist containing weird monsters.
In Castlevania: Symphony of the Night, Alucard can actually change into a playable Fog of Doom once you've found the right items: with the "Form of Mist" and "Gas Cloud" relics, his mist form is invincible and causes damage to any enemies within it, while constantly draining a small amount of MP. It's every bit the Game Breaker it sounds like, though you can only get it near the end of the game.
The creepy fog in Sei-an City in Ōkami is slowly killing everyone in the city. Turns out it's caused by a monster called Blight, which is living in the Emperor's Stomach.
The Legend of Zelda: Twilight Princess, once you head to the Forest Temple in human form with Midna, you have to go through a mass of purple fog following a monkey with your lantern. The fog doesn't affect your enemies, sadly, making it very annoying when you're running along and the monkey suddenly stops in terror and you careen into purple death. The mist in the Earth Temple of The Legend of Zelda: The Wind Waker is infamous for not only robbing you of your item use, but also for concealing none other than the dreaded Floormasters.
In Dwarf Fortress the surfaces of evil regions have a variety of clouds of randomly named materials ("execrable soot", "accursed gloom", etc) which cause randomly determined symptoms, ranging from mild dizziness to all of your internal organs rotting to becoming a zombie.
Rescue on Fractalus!: The acidic atmosphere of the eponymous planet both reduces visibility and dissolves the flight suits of exposed pilots.
The cloud of Joker Venom that The Joker doses Gotham with in one Batman: The Animated Series episode could qualify as the 'insanity-inducing' variant... But you had to be exposed to it for a long time in order for the insanity to take effect.
Code Lyoko has XANA entering the real world as a gas/liquid when its schemes involve possessing something, which sometimes ends up being even more gas.
This is also XANA's final form upon being defeated. After being destroyed in Lyoko, William is depossessed and XANA formulates in a gaseous fog before dissolving.
The Legend of Korra has a somewhat chilling example for a kids' show with the "Fog of Lost Souls'', which eternally imprisons its victims in their most traumatic memories.
London is known for its Ominous Fog, thanks to much of the city being in a large river valley kn own as the Thames Basin. Combine that with extensive industrialisation and a lack of environmental regulations and you have a recipe for this trope. Smog conditions got bad enough to be a public health hazard fairly regularly, but the last and worst incident was in 1952: From Friday the 5th of December to Tuesday the 9th of December, London was enshrouded with what has come to be called the Great Smog of 1952. One of the worst pollution episodes in history, the Great Smog killed nearly 4000 people, and hospitalized nearly 100,000 more from respiratory tract infections and hypoxia (the inability to get enough oxygen). This finally convinced the government that enough was enough, and the UK's first Clean Air Act was passed soon after.
A nearly identical situation happened in the mill town of Donora, PA in 1948 which led to the death of 20 and the infection of nearly 7,000, nearly half of the town's population, from respiratory illness. The smog also left many survivors with lasting illness. The event is still considered one of the worst environmental disasters in US history.
Take the inherent danger of driving in thick fog with some Californians' infamous driving habits...and you have a recipe for disaster.
Time and medical statistics have made it increasingly clear that the dust-clouds from the World Trade Center attacks constituted a slow-acting example of this, given the number of rescue personnel who have succumbed to respiratory disease and cancer after breathing in those dust particles.
The 2010 forest and peat fires in Central Russia caused a Smoke Of Doom in many Russian cities including Moscow. Carbon monoxide is quite a dangerous gas.
Many chemical weapons take on this feature when released, from the viewpoint of the victims. This sometimes crosses over with Deadly Gas.